| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)|This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1080) |
| External Link | https://ncbi.nlm.nih.gov/gene/1080 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CFTR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.0217283 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0147666 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.0116227 |
| CLDN10 | claudin 10 | 0.0110547 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0109786 |
| ANXA1 | annexin A1 | 0.0109185 |
| COPS7A | COP9 signalosome subunit 7A | 0.0108093 |
| ARG1 | arginase 1 | 0.0107804 |
| RGCC | regulator of cell cycle | 0.0106426 |
| RBM34 | RNA binding motif protein 34 | 0.0106119 |
| STOM | stomatin | 0.0105446 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0103964 |
| MT1X | metallothionein 1X | 0.0103775 |
| CSTA | cystatin A (stefin A) | 0.0101574 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.0101452 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0101341 |
| DEFB1 | defensin, beta 1 | 0.0100242 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0099841 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00984041 |
| KRT5 | keratin 5, type II | 0.00981539 |
| DAXX | death-domain associated protein | 0.00936269 |
| ADD3 | adducin 3 (gamma) | 0.00925802 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00914604 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | 0.00911104 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00903974 |
| LBH | limb bud and heart development | 0.00897645 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00891382 |
| ADIRF | adipogenesis regulatory factor | 0.00890701 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00887104 |
| FGF13 | fibroblast growth factor 13 | 0.00878534 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00873073 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00862633 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00850996 |
| FOXG1 | forkhead box G1 | 0.00846194 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.0084459 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00839576 |
| TEX10 | testis expressed 10 | 0.00838618 |
| COCH | cochlin | 0.00834301 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00832244 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00829122 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00821612 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.00813575 |
| METTL7A | methyltransferase like 7A | 0.00812979 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00811614 |
| RAB13 | RAB13, member RAS oncogene family | 0.00809808 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00809415 |
| PON2 | paraoxonase 2 | 0.00806887 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00805266 |
| KRT14 | keratin 14, type I | 0.00804461 |
| TAC1 | tachykinin, precursor 1 | 0.00803948 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00800337 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00796383 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00790165 |
| LRRC23 | leucine rich repeat containing 23 | 0.00787133 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00784826 |
| MT1G | metallothionein 1G | 0.00783307 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00782597 |
| ERGIC3 | ERGIC and golgi 3 | 0.0078096 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00780647 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00779541 |
| CLU | clusterin | 0.00778858 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00777048 |
| GPM6B | glycoprotein M6B | 0.00776633 |
| NRN1 | neuritin 1 | 0.00762032 |
| FBXO11 | F-box protein 11 | 0.00761956 |
| TRIM29 | tripartite motif containing 29 | 0.00758852 |
| KRT13 | keratin 13, type I | 0.00757275 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00756746 |
| S100A2 | S100 calcium binding protein A2 | 0.00752127 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00747713 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00745516 |
| KRT6A | keratin 6A, type II | 0.0074428 |
| EAF2 | ELL associated factor 2 | 0.00740503 |
| PAH | phenylalanine hydroxylase | 0.00735544 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00734649 |
| UPK1B | uroplakin 1B | 0.0073378 |
| NFIB | nuclear factor I/B | 0.00731823 |
| DPYS | dihydropyrimidinase | 0.00728686 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00722951 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00722361 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00719549 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.00716785 |
| GNAS | GNAS complex locus | 0.00716633 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00716328 |
| AK4 | adenylate kinase 4 | 0.0071334 |
| S100P | S100 calcium binding protein P | 0.00712369 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00710898 |
| NEBL | nebulette | 0.00710288 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00710254 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00708723 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00707282 |
| ERGIC2 | ERGIC and golgi 2 | 0.00704563 |
| CHPT1 | choline phosphotransferase 1 | 0.00704315 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00702981 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00702667 |
| NNMT | nicotinamide N-methyltransferase | 0.0069887 |
| RABEPK | Rab9 effector protein with kelch motifs | 0.00698273 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00697431 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.00697238 |
| EPCAM | epithelial cell adhesion molecule | 0.00696457 |
| CD9 | CD9 molecule | 0.00692253 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00687574 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00687452 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00686261 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00685531 |
| AUTS2 | autism susceptibility candidate 2 | 0.00685033 |
| XIC | X chromosome inactivation center | 0.00684995 |
| MT1H | metallothionein 1H | 0.00684838 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00683244 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00681935 |
| PLG | plasminogen | 0.00674643 |
| EAPP | E2F-associated phosphoprotein | 0.00674266 |
| KRT23 | keratin 23, type I | 0.00673926 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00669553 |
| KRT7 | keratin 7, type II | 0.00667781 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.00666042 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00665948 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00664859 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00663924 |
| MLF1 | myeloid leukemia factor 1 | 0.00661108 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00660104 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00657327 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.0065693 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00653743 |
| RPL14 | ribosomal protein L14 | 0.00652691 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.0065135 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00650458 |
| DAZAP2 | DAZ associated protein 2 | 0.00650225 |
| AQP4 | aquaporin 4 | 0.00649151 |
| IQCG | IQ motif containing G | 0.00649112 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | 0.00647451 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00646218 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00644502 |
| F9 | coagulation factor IX | 0.00644401 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.00639226 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00636308 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00636037 |
| S100A7 | S100 calcium binding protein A7 | 0.00632682 |
| HK1 | hexokinase 1 | 0.00631235 |
| FAM107A | family with sequence similarity 107, member A | 0.00628207 |
| ESD | esterase D | 0.00627155 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00626615 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00626171 |
| MT2A | metallothionein 2A | 0.00625818 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00624768 |
| LTF | lactotransferrin | 0.00624597 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00624242 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00624194 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00623833 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00620215 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00618891 |
| CPB2 | carboxypeptidase B2 (plasma) | 0.00618205 |
| TMEM231 | transmembrane protein 231 | 0.00617334 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00613275 |
| C14ORF105 | chromosome 14 open reading frame 105 | 0.00613096 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00613047 |
| CRIP2 | cysteine-rich protein 2 | 0.00612729 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0061236 |
| AFM | afamin | 0.00608455 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00605703 |
| GTF3A | general transcription factor IIIA | 0.0060478 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00604774 |
| PRKD3 | protein kinase D3 | 0.00603144 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 | 0.0060268 |
| TAGLN2 | transgelin 2 | 0.00602563 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00602026 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00601819 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.0060139 |
| AREG | amphiregulin | 0.00600317 |
| EMP2 | epithelial membrane protein 2 | 0.00600172 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00599983 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00598926 |
| HOPX | HOP homeobox | 0.00597905 |
| KRT17 | keratin 17, type I | 0.0059561 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00595315 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00595132 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00594327 |
| CLDN8 | claudin 8 | 0.00594301 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.00593986 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00593074 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00592896 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00591964 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0059013 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00588237 |
| NGRN | neugrin, neurite outgrowth associated | 0.00588082 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.00587818 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00586152 |
| RPA3 | replication protein A3, 14kDa | 0.00585882 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.00585121 |
| CHEK2 | checkpoint kinase 2 | 0.00584803 |
| ABI1 | abl-interactor 1 | 0.00584219 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.00583885 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00583873 |
| NANS | N-acetylneuraminic acid synthase | 0.00582489 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00581532 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00581256 |
| TFCP2L1 | transcription factor CP2-like 1 | 0.00578859 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | 0.00578295 |
| CADM1 | cell adhesion molecule 1 | 0.00577725 |
| AQP9 | aquaporin 9 | 0.00576539 |
| MT1F | metallothionein 1F | 0.00576133 |
| MPZL2 | myelin protein zero-like 2 | 0.00574739 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00574397 |
| PSPC1 | paraspeckle component 1 | 0.00573902 |
| RCAN1 | regulator of calcineurin 1 | 0.00573881 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00573583 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | 0.00572818 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00571952 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00570859 |
| BCL2A1 | BCL2-related protein A1 | 0.00570762 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.0057069 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.00569843 |
| SERINC5 | serine incorporator 5 | 0.00569014 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00568012 |
| CAMLG | calcium modulating ligand | 0.00567971 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00567025 |
| H1-10 | H1.10 linker histone | 0.00566581 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0056635 |
| FZD6 | frizzled class receptor 6 | 0.00566114 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.00564336 |
| LAGE3 | L antigen family, member 3 | 0.00563025 |
| PTGES | prostaglandin E synthase | 0.00562941 |
| HSBP1 | heat shock factor binding protein 1 | 0.00562657 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00562637 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00562103 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00561755 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00561593 |
| IL6ST | interleukin 6 signal transducer | 0.00560808 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00560238 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00560197 |
| BBX | bobby sox homolog (Drosophila) | 0.00559933 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00559641 |
| PASK | PAS domain containing serine/threonine kinase | 0.00559557 |
| LYRM1 | LYR motif containing 1 | 0.0055933 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00558734 |
| RDX | radixin | 0.00557858 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00557725 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00557528 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 0.00557473 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00557187 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00556776 |
| ENG | endoglin | 0.00556483 |
| CBFB | core-binding factor, beta subunit | 0.00556392 |
| STON1 | stonin 1 | 0.00554344 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00553914 |
| SMAD2 | SMAD family member 2 | 0.00552861 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00551824 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00551254 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.005509 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00550465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RTN2 | reticulon 2 | -0.016942 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0165727 |
| MMP1 | matrix metallopeptidase 1 | -0.016251 |
| GAS1 | growth arrest-specific 1 | -0.0160714 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0152192 |
| POSTN | periostin, osteoblast specific factor | -0.0145891 |
| CKM | creatine kinase, muscle | -0.0127876 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.011803 |
| MB | myoglobin | -0.0116406 |
| COLEC12 | collectin sub-family member 12 | -0.011444 |
| PDLIM3 | PDZ and LIM domain 3 | -0.0114397 |
| PRDX2 | peroxiredoxin 2 | -0.011294 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.0112759 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0110815 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0110677 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0109921 |
| DES | desmin | -0.0108104 |
| SCG5 | secretogranin V | -0.0107115 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0104496 |
| MXRA5 | matrix-remodelling associated 5 | -0.0103665 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0103514 |
| EGR2 | early growth response 2 | -0.0102972 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.0102128 |
| TTN | titin | -0.00995469 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00984612 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00971647 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00969456 |
| ZWINT | ZW10 interacting kinetochore protein | -0.0096043 |
| DUSP5 | dual specificity phosphatase 5 | -0.00958862 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00949875 |
| TNNC2 | troponin C type 2 (fast) | -0.00944667 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00942125 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00941915 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00936711 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00923848 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00913392 |
| FGL2 | fibrinogen-like 2 | -0.00895642 |
| CDA | cytidine deaminase | -0.00893537 |
| RXRA | retinoid X receptor, alpha | -0.00893017 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0088601 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00885569 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00882778 |
| BMP4 | bone morphogenetic protein 4 | -0.00882293 |
| TYMS | thymidylate synthetase | -0.00880403 |
| FLNC | filamin C, gamma | -0.00879516 |
| NID2 | nidogen 2 (osteonidogen) | -0.00876793 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00876362 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00873585 |
| TGFB3 | transforming growth factor, beta 3 | -0.00871267 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0087024 |
| SLN | sarcolipin | -0.00865753 |
| EMP3 | epithelial membrane protein 3 | -0.00865479 |
| NRCAM | neuronal cell adhesion molecule | -0.00860747 |
| WT1 | Wilms tumor 1 | -0.00856381 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00856114 |
| FBLN1 | fibulin 1 | -0.00854802 |
| KRT19 | keratin 19, type I | -0.00851886 |
| TYMP | thymidine phosphorylase | -0.00850206 |
| PFKM | phosphofructokinase, muscle | -0.00846674 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0084624 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00830781 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00830341 |
| PEG3 | paternally expressed 3 | -0.00827933 |
| NXN | nucleoredoxin | -0.00826393 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00826157 |
| TNNC1 | troponin C type 1 (slow) | -0.00819673 |
| CDC20 | cell division cycle 20 | -0.00813731 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00811493 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00811218 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00808022 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00803021 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00802349 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00801135 |
| KLHL41 | kelch-like family member 41 | -0.00799688 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00797647 |
| ASPN | asporin | -0.00791255 |
| MX2 | MX dynamin-like GTPase 2 | -0.007903 |
| MX1 | MX dynamin-like GTPase 1 | -0.00788129 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00786267 |
| REC8 | REC8 meiotic recombination protein | -0.00785337 |
| IRS1 | insulin receptor substrate 1 | -0.0078275 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.0078251 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00781383 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00778982 |
| TLN1 | talin 1 | -0.00768096 |
| NID1 | nidogen 1 | -0.00764264 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00764199 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00762229 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.00759535 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00759083 |
| MEST | mesoderm specific transcript | -0.0075741 |
| PCLAF | PCNA clamp associated factor | -0.00754889 |
| FST | follistatin | -0.00754296 |
| NELL2 | NEL-like 2 (chicken) | -0.00752326 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00750813 |
| STX3 | syntaxin 3 | -0.00750336 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00740734 |
| REG1A | regenerating islet-derived 1 alpha | -0.00739561 |
| DPT | dermatopontin | -0.00737453 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00736204 |
| MYBPC2 | myosin binding protein C, fast type | -0.00735133 |
| MFAP5 | microfibrillar associated protein 5 | -0.00735041 |
| COL5A1 | collagen, type V, alpha 1 | -0.00734409 |
| CTSZ | cathepsin Z | -0.0072723 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00726983 |
| FLNA | filamin A, alpha | -0.00725822 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00724738 |
| SVIL | supervillin | -0.00722927 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00720462 |
| LRRC15 | leucine rich repeat containing 15 | -0.00720142 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0071839 |
| PLN | phospholamban | -0.00718292 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00716766 |
| RTN3 | reticulon 3 | -0.00712853 |
| GRAMD4 | GRAM domain containing 4 | -0.00712237 |
| TMSB15A | thymosin beta 15a | -0.00707437 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00707016 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.007068 |
| SMTN | smoothelin | -0.00706144 |
| FZD2 | frizzled class receptor 2 | -0.00705284 |
| APOD | apolipoprotein D | -0.00703538 |
| XAF1 | XIAP associated factor 1 | -0.0069938 |
| MTMR11 | myotubularin related protein 11 | -0.00699155 |
| FCGBP | Fc fragment of IgG binding protein | -0.00694377 |
| CD320 | CD320 molecule | -0.00693946 |
| NREP | neuronal regeneration related protein | -0.00693405 |
| PEG10 | paternally expressed 10 | -0.00692995 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00691274 |
| PMP22 | peripheral myelin protein 22 | -0.00690424 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00689285 |
| NAV3 | neuron navigator 3 | -0.00688274 |
| COL10A1 | collagen, type X, alpha 1 | -0.00686566 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00686291 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00683706 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00680355 |
| LAMA4 | laminin, alpha 4 | -0.00678831 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00677309 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0067721 |
| CHGB | chromogranin B | -0.00676401 |
| MYRF | myelin regulatory factor | -0.00674674 |
| CALCA | calcitonin-related polypeptide alpha | -0.0067373 |
| HOXB2 | homeobox B2 | -0.00673061 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00672977 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00672011 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00671626 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00668993 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00667877 |
| S100A4 | S100 calcium binding protein A4 | -0.00666617 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0066627 |
| DMXL2 | Dmx-like 2 | -0.00665698 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00664808 |
| PRKCB | protein kinase C, beta | -0.00661417 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00661235 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0065803 |
| TLR4 | toll-like receptor 4 | -0.00656539 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00655852 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00654558 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00651942 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.0065076 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00650055 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0064929 |
| BTG2 | BTG family, member 2 | -0.00646756 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0064588 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.00645636 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00644974 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0064421 |
| GOLGA8A | golgin A8 family, member A | -0.00642872 |
| BCHE | butyrylcholinesterase | -0.00641833 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00640887 |
| VCAN | versican | -0.00640445 |
| ENO3 | enolase 3 (beta, muscle) | -0.00639844 |
| COL9A2 | collagen, type IX, alpha 2 | -0.0063953 |
| ACTN2 | actinin, alpha 2 | -0.00638137 |
| AMOTL2 | angiomotin like 2 | -0.00637955 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00636692 |
| PMM2 | phosphomannomutase 2 | -0.00636668 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00636204 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00635121 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.00634536 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00634179 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00633522 |
| MYOT | myotilin | -0.0063319 |
| PDGFC | platelet derived growth factor C | -0.00632832 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00631067 |
| CCDC86 | coiled-coil domain containing 86 | -0.00629062 |
| ACO2 | aconitase 2, mitochondrial | -0.00628887 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00627527 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00627085 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00627065 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00626455 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0062555 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00625223 |
| SMPX | small muscle protein, X-linked | -0.00622968 |
| CCL11 | chemokine (C-C motif) ligand 11 | -0.00622652 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00622568 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00619737 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | -0.00618976 |
| SLC16A6 | solute carrier family 16, member 6 | -0.006181 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00617482 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00616861 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.00612874 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00612585 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00612426 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00609684 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.0060921 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00608797 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00608261 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00607877 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00606868 |
| DCN | decorin | -0.00606822 |
| STK38 | serine/threonine kinase 38 | -0.00605065 |
| CBS | cystathionine-beta-synthase | -0.00604626 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.00603571 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00603257 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00603079 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00602791 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00602462 |
| OBSL1 | obscurin-like 1 | -0.00600792 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00600147 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00599877 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00599676 |
| DACH1 | dachshund family transcription factor 1 | -0.00599378 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00598941 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00598759 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00597243 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | -0.00596519 |
| TOR4A | torsin family 4, member A | -0.00596472 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00595935 |
| DCHS1 | dachsous cadherin-related 1 | -0.00595771 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | -0.00594709 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00592695 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -0.00589876 |
| PAX6 | paired box 6 | -0.00589694 |
| CA3 | carbonic anhydrase III | -0.00587595 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00586748 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | -0.00586161 |
| PYCARD | PYD and CARD domain containing | -0.00585586 |
| HIC2 | hypermethylated in cancer 2 | -0.00584542 |
| ADORA2B | adenosine A2b receptor | -0.00584287 |
| CFD | complement factor D (adipsin) | -0.00584285 |
| HDC | histidine decarboxylase | -0.00582193 |
| ANGPTL2 | angiopoietin-like 2 | -0.00581777 |
| FILIP1L | filamin A interacting protein 1-like | -0.00580948 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00578752 |
| TXLNA | taxilin alpha | -0.0057743 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00577369 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00576533 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00576018 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0057531 |
