CGAS Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Similar Terms
Downloads & Tools

Genes

325 genes differentially expressed following the CGAS gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TNR tenascin R 2.73648
BSPH1 binder of sperm protein homolog 1 2.73648
WNT16 wingless-type MMTV integration site family, member 16 2.73648
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 2.73648
EPPIN epididymal peptidase inhibitor 2.73648
KPNA7 karyopherin alpha 7 (importin alpha 8) 2.73648
DYNAP dynactin associated protein 2.73648
CPO carboxypeptidase O 2.73648
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.73648
ZIC4 Zic family member 4 2.73648
SMIM22 small integral membrane protein 22 2.73648
WFDC8 WAP four-disulfide core domain 8 2.73648
FAM3D family with sequence similarity 3, member D 2.73648
MAGEB17 melanoma antigen family B17 2.73648
YIPF7 Yip1 domain family, member 7 2.73648
GYS2 glycogen synthase 2 (liver) 2.73648
TBX22 T-box 22 2.73648
CNR2 cannabinoid receptor 2 (macrophage) 2.73648
KIF1C-AS1 KIF1C antisense RNA 1 2.73648
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.73648
GOLGA8K golgin A8 family, member K 2.73648
CXORF58 chromosome X open reading frame 58 2.73648
TMEM176B transmembrane protein 176B 2.64727
HCRTR1 hypocretin (orexin) receptor 1 2.64727
IZUMO3 IZUMO family member 3 2.64727
RHD Rh blood group, D antigen 2.64727
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.64727
FAM167B family with sequence similarity 167, member B 2.64727
MYL1 myosin, light chain 1, alkali; skeletal, fast 2.64727
HIC1 hypermethylated in cancer 1 2.64727
GYPB glycophorin B (MNS blood group) 2.64727
LRRD1 leucine-rich repeats and death domain containing 1 2.64727
MYO7B myosin VIIB 2.64727
CCR9 chemokine (C-C motif) receptor 9 2.64727
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.64727
TCP11 t-complex 11, testis-specific 2.64727
ETV2 ets variant 2 2.64727
OSGIN1 oxidative stress induced growth inhibitor 1 2.64727
CRH corticotropin releasing hormone 2.64727
C1ORF141 chromosome 1 open reading frame 141 2.64727
ARSF arylsulfatase F 2.64727
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.64727
FBLN7 fibulin 7 2.64727
BFSP2 beaded filament structural protein 2, phakinin 2.64727
MUSK muscle, skeletal, receptor tyrosine kinase 2.64727
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.64727
IL2RA interleukin 2 receptor, alpha 2.64727
LRG1 leucine-rich alpha-2-glycoprotein 1 2.64727
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.64727
ZNF560 zinc finger protein 560 2.64727
AVP arginine vasopressin 2.64727
MRPL53 mitochondrial ribosomal protein L53 2.64727
SIRPB1 signal-regulatory protein beta 1 2.64727
CCNB3 cyclin B3 2.64727
OR51A7 olfactory receptor, family 51, subfamily A, member 7 2.64727
FOLR1 folate receptor 1 (adult) 2.64727
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.64727
SPATA25 spermatogenesis associated 25 2.64727
MYL10 myosin, light chain 10, regulatory 2.64727
ZC3H11C zinc finger CCCH-type containing 11C 2.64727
KRT86 keratin 86, type II 2.64727
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.64727
SAPCD1 suppressor APC domain containing 1 2.64727
STAT4 signal transducer and activator of transcription 4 2.64727
FYB1 FYN binding protein 1 2.64727
CALHM5 calcium homeostasis modulator family member 5 2.64727
TAFA3 TAFA chemokine like family member 3 2.64727
CBY2 chibby family member 2 2.64727
MYMK myomaker, myoblast fusion factor 2.64727
SMIM35 small integral membrane protein 35 2.64727
LOC124903372 uncharacterized LOC124903372 2.64727
NOTCH2NLB notch 2 N-terminal like B 2.64727
EXOC1L exocyst complex component 1 like 2.64727
FAM240C family with sequence similarity 240 member C 2.64727
LY6K lymphocyte antigen 6 complex, locus K 2.64727
FAM228A family with sequence similarity 228, member A 2.64727
F5 coagulation factor V (proaccelerin, labile factor) 2.64727
OR5P3 olfactory receptor, family 5, subfamily P, member 3 2.64727
FER1L6 fer-1-like family member 6 2.64727
MTRF1L mitochondrial translational release factor 1-like 2.64727
SLC22A10 solute carrier family 22, member 10 2.64727
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.64727
H2BW1 H2B.W histone 1 2.64727
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 2.64727
PTTG2 pituitary tumor-transforming 2 2.64727
GGT5 gamma-glutamyltransferase 5 2.64727
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.64727
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.64727
HAPLN2 hyaluronan and proteoglycan link protein 2 2.64727
RNF113B ring finger protein 113B 2.64727
CHEK2 checkpoint kinase 2 2.64727
C7 complement component 7 2.64727
FRK fyn-related Src family tyrosine kinase 2.64727
PXDC1 PX domain containing 1 2.64727
SMIM32 small integral membrane protein 32 2.64727
LYZ lysozyme 2.64727
HPGDS hematopoietic prostaglandin D synthase 2.64727
C2ORF66 chromosome 2 open reading frame 66 2.64727
NOX1 NADPH oxidase 1 2.64727
GCOM1 GRINL1A complex locus 1 2.64727
CPSF4L cleavage and polyadenylation specific factor 4-like 2.64727
DEFB107B defensin, beta 107B 2.64727
POF1B premature ovarian failure, 1B 2.64727
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.64727
CCL27 chemokine (C-C motif) ligand 27 2.64727
IL1A interleukin 1, alpha 2.64727
LMX1B LIM homeobox transcription factor 1, beta 2.64727
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.64727
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.64727
ALOX15B arachidonate 15-lipoxygenase, type B 2.64727
CHRM4 cholinergic receptor, muscarinic 4 2.64727
FKBP1C FK506 binding protein 1C 2.64727
APOC2 apolipoprotein C-II 2.64727
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.64727
PLA2G12B phospholipase A2, group XIIB 2.64727
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.64727
ADGRD1 adhesion G protein-coupled receptor D1 2.64727
LRRC19 leucine rich repeat containing 19 2.64727
TEX12 testis expressed 12 2.64727
ZCCHC12 zinc finger, CCHC domain containing 12 2.64727
KISS1 KiSS-1 metastasis-suppressor 2.64727
BCL2L15 BCL2-like 15 2.64727
TAT tyrosine aminotransferase 2.64727
QRFP pyroglutamylated RFamide peptide 2.64727
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.64727
EFCC1 EF-hand and coiled-coil domain containing 1 2.64727
NT5C1A 5'-nucleotidase, cytosolic IA 2.64727
PCDHGA7 protocadherin gamma subfamily A, 7 2.64727
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.64727
C2CD4D C2 calcium-dependent domain containing 4D 2.64727
MMP3 matrix metallopeptidase 3 2.64727
HES2 hes family bHLH transcription factor 2 2.64727
TMEM255A transmembrane protein 255A 2.64727
NLRP6 NLR family, pyrin domain containing 6 2.64727
NLRP3 NLR family, pyrin domain containing 3 2.64727
ICAM2 intercellular adhesion molecule 2 2.64727
GOLGA8O golgin A8 family, member O 2.64727
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.64727
PADI4 peptidyl arginine deiminase, type IV 2.64727
AMPD1 adenosine monophosphate deaminase 1 2.64727
TMEM52B transmembrane protein 52B 2.64727
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.64727
ARSH arylsulfatase family, member H 2.64727
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.64727
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.64727
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.64727
TEX29 testis expressed 29 2.64727
SFTA2 surfactant associated 2 2.64727
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.64727
CIB4 calcium and integrin binding family member 4 2.64727
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.64727
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.64727
TMPRSS12 transmembrane (C-terminal) protease, serine 12 2.64727
FGF10 fibroblast growth factor 10 2.64727
DCAF8 DDB1 and CUL4 associated factor 8 2.63608
PHKA2 phosphorylase kinase, alpha 2 (liver) 2.6168
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.6168
C8ORF76 chromosome 8 open reading frame 76 2.58645
GSDMB gasdermin B 2.53748
POLD2 polymerase (DNA directed), delta 2, accessory subunit 2.53323
SNX17 sorting nexin 17 2.50068
RAI14 retinoic acid induced 14 2.49184
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.46804
GDF15 growth differentiation factor 15 2.44112
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.42603
CPZ carboxypeptidase Z 2.42252
SPIDR scaffolding protein involved in DNA repair 2.39144
TRAF4 TNF receptor-associated factor 4 2.37794
DHCR24 24-dehydrocholesterol reductase 2.37688
SLC30A9 solute carrier family 30 (zinc transporter), member 9 2.37512
NPIPB11 nuclear pore complex interacting protein family, member B11 2.37512
SSC5D scavenger receptor cysteine rich family, 5 domains 2.36393
PCNX1 pecanex 1 2.36393
CXCL14 chemokine (C-X-C motif) ligand 14 2.30249
PARP15 poly (ADP-ribose) polymerase family, member 15 2.30249
AMBP alpha-1-microglobulin/bikunin precursor 2.30217
TARDBP TAR DNA binding protein 2.30217
MYBPHL myosin binding protein H-like 2.30217
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 2.2995
METTL18 methyltransferase like 18 2.28577
SF3A2 splicing factor 3a, subunit 2, 66kDa 2.27222
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 2.22647
ARMCX1 armadillo repeat containing, X-linked 1 2.20929
APOO apolipoprotein O 2.20077
TMCO4 transmembrane and coiled-coil domains 4 2.19424
SARDH sarcosine dehydrogenase 2.16755
COL16A1 collagen, type XVI, alpha 1 2.11393
STRADA STE20-related kinase adaptor alpha 2.11393
PRMT8 protein arginine methyltransferase 8 2.10081
ZNF423 zinc finger protein 423 2.10081
PLD3 phospholipase D family, member 3 2.08315
COPRS coordinator of PRMT5, differentiation stimulator 2.08191
KCNIP1 Kv channel interacting protein 1 2.08136
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.06836
GDF11 growth differentiation factor 11 2.06529
RESF1 retroelement silencing factor 1 2.06529
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.06529
RGS7 regulator of G-protein signaling 7 2.05966
TMEM9 transmembrane protein 9 2.05584
LDB2 LIM domain binding 2 2.04232
ZDHHC21 zinc finger, DHHC-type containing 21 2.04006
AMPD2 adenosine monophosphate deaminase 2 2.02855
SFMBT2 Scm-like with four mbt domains 2 2.02855
RIPOR3 RIPOR family member 3 2.02855
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 2.02099
SETD5 SET domain containing 5 2.02099
ZIC1 Zic family member 1 2.01525
CRHR2 corticotropin releasing hormone receptor 2 2.01525
FAM110D family with sequence similarity 110, member D 2.01525

decreased expression

Symbol Name Standardized Value
RAB9B RAB9B, member RAS oncogene family -2.73648
MYL9 myosin, light chain 9, regulatory -2.73648
C1ORF53 chromosome 1 open reading frame 53 -2.73648
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.65355
CFAP119 cilia and flagella associated protein 119 -2.65355
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -2.65355
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -2.64727
RXRB retinoid X receptor, beta -2.64727
TUBGCP6 tubulin, gamma complex associated protein 6 -2.64727
ANKRD12 ankyrin repeat domain 12 -2.64727
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -2.64727
MVD mevalonate (diphospho) decarboxylase -2.64727
DLEC1 deleted in lung and esophageal cancer 1 -2.64727
LBH limb bud and heart development -2.64727
SLC67A1 solute carrier family 67 member 1 -2.64727
SLC25A39 solute carrier family 25, member 39 -2.64727
GPNMB glycoprotein (transmembrane) nmb -2.64727
FRMPD2 FERM and PDZ domain containing 2 -2.64374
CIMAP2 ciliary microtubule associated protein 2 -2.64374
MOB3C MOB kinase activator 3C -2.64374
CLK4 CDC-like kinase 4 -2.62298
FAR1 fatty acyl CoA reductase 1 -2.6168
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -2.6168
CXCL2 chemokine (C-X-C motif) ligand 2 -2.6168
S1PR1 sphingosine-1-phosphate receptor 1 -2.6168
THPO thrombopoietin -2.6168
SGK2 serum/glucocorticoid regulated kinase 2 -2.6168
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 -2.6168
FXYD3 FXYD domain containing ion transport regulator 3 -2.6168
GPR78 G protein-coupled receptor 78 -2.6168
OIT3 oncoprotein induced transcript 3 -2.6168
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.6168
BTC betacellulin -2.6168
C8ORF74 chromosome 8 open reading frame 74 -2.6168
LAMP5 lysosomal-associated membrane protein family, member 5 -2.6168
ESR1 estrogen receptor 1 -2.6168
PNLIPRP2 pancreatic lipase-related protein 2 -2.6168
CLDN14 claudin 14 -2.6168
CD52 CD52 molecule -2.6168
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.6168
EPHA10 EPH receptor A10 -2.6168
MISP3 MISP family member 3 -2.6168
MYLK4 myosin light chain kinase family, member 4 -2.6168
SCIN scinderin -2.6168
SPMIP8 sperm microtubule inner protein 8 -2.6168
FSHR follicle stimulating hormone receptor -2.6168
ENDOU endonuclease, polyU-specific -2.6168
PRCD progressive rod-cone degeneration -2.6168
SPTBN5 spectrin, beta, non-erythrocytic 5 -2.6168
PRRT4 proline-rich transmembrane protein 4 -2.6168
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta -2.57644
C2CD4C C2 calcium-dependent domain containing 4C -2.57644
BAIAP3 BAI1-associated protein 3 -2.57644
SOCS6 suppressor of cytokine signaling 6 -2.57065
ZNF239 zinc finger protein 239 -2.55838
WNT3 wingless-type MMTV integration site family, member 3 -2.55776
ZNF774 zinc finger protein 774 -2.51319
COL8A1 collagen, type VIII, alpha 1 -2.48414
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.47722
RBM4B RNA binding motif protein 4B -2.47246
GLYATL1 glycine-N-acyltransferase-like 1 -2.47246
FBXW10B F-box and WD repeat domain containing 10B -2.47246
FUNDC1 FUN14 domain containing 1 -2.43971
RNF19B ring finger protein 19B -2.43971
KSR1 kinase suppressor of ras 1 -2.39144
ZC3H7A zinc finger CCCH-type containing 7A -2.36912
EPN2 epsin 2 -2.35429
YIPF3 Yip1 domain family, member 3 -2.35094
BMP1 bone morphogenetic protein 1 -2.34919
VWA5B1 von Willebrand factor A domain containing 5B1 -2.34919
ART5 ADP-ribosyltransferase 5 -2.31045
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -2.31023
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.30217
RPN1 ribophorin I -2.2995
AGFG2 ArfGAP with FG repeats 2 -2.2995
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -2.2995
SMIM36 small integral membrane protein 36 -2.28577
ANKRD42 ankyrin repeat domain 42 -2.28577
WSCD2 WSC domain containing 2 -2.28577
SOX8 SRY (sex determining region Y)-box 8 -2.28577
ANAPC5 anaphase promoting complex subunit 5 -2.27582
LUC7L2 LUC7-like 2 (S. cerevisiae) -2.2176
SLC67A2 solute carrier family 67 member 2 -2.20929
ZFC3H1 zinc finger, C3H1-type containing -2.20727
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.20271
B2M beta-2-microglobulin -2.1954
KIF9 kinesin family member 9 -2.19424
TSLIG2 tRNA splicing ligase complex subunit 2 -2.17369
RPL23A ribosomal protein L23a -2.12802
PTCH2 patched 2 -2.11575
MARCKS myristoylated alanine-rich protein kinase C substrate -2.11393
SOX10 SRY (sex determining region Y)-box 10 -2.11393
HLA-DMB major histocompatibility complex, class II, DM beta -2.11393
SCN7A sodium channel, voltage gated, type VII alpha subunit -2.1067
TMEM185A transmembrane protein 185A -2.10081
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.09813
BANK1 B-cell scaffold protein with ankyrin repeats 1 -2.09813
KLHL8 kelch-like family member 8 -2.09755
MT1X metallothionein 1X -2.08191
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 -2.07251
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.06836
RPL11 ribosomal protein L11 -2.06836
SMDT1 single-pass membrane protein with aspartate-rich tail 1 -2.06529
AOAH acyloxyacyl hydrolase (neutrophil) -2.06529
FLT4 fms-related tyrosine kinase 4 -2.06529
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -2.06529
SBK2 SH3 domain binding kinase family, member 2 -2.06529
PCDHA4 protocadherin alpha 4 -2.06529
FAM78A family with sequence similarity 78, member A -2.06529
SH3RF2 SH3 domain containing ring finger 2 -2.06529
SIRAL2 SIR2 antiphage like 2 -2.06072
POU6F1 POU class 6 homeobox 1 -2.04804
CGAS cyclic GMP-AMP synthase -2.03558
GUCD1 guanylyl cyclase domain containing 1 -2.02855
SPA17 sperm autoantigenic protein 17 -2.02855
L3MBTL1 l(3)mbt-like 1 (Drosophila) -2.00401