CHD1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chromodomain helicase DNA binding protein 1|The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1105)
External Link https://ncbi.nlm.nih.gov/gene/1105
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Genes

500 genes differentially expressed following the CHD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V 0.0137528
ASPN asporin 0.0136914
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0136716
SFRP1 secreted frizzled-related protein 1 0.0129939
CADM1 cell adhesion molecule 1 0.0117704
TM4SF1 transmembrane 4 L six family member 1 0.0117492
FABP4 fatty acid binding protein 4, adipocyte 0.0117177
TBX3 T-box 3 0.0116533
SOX9 SRY (sex determining region Y)-box 9 0.0116214
DCN decorin 0.0114869
FN1 fibronectin 1 0.0113768
KRT23 keratin 23, type I 0.0109636
LUM lumican 0.0109471
PLAT plasminogen activator, tissue 0.0106882
RRAGA Ras-related GTP binding A 0.0104456
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0104331
SPON2 spondin 2, extracellular matrix protein 0.0102991
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0102761
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0100549
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00996808
PDZRN3 PDZ domain containing ring finger 3 0.0099592
ANXA5 annexin A5 0.00989198
GPNMB glycoprotein (transmembrane) nmb 0.00980585
MT1E metallothionein 1E 0.00974868
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00958566
BMP4 bone morphogenetic protein 4 0.00935923
GPX2 glutathione peroxidase 2 0.00935408
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00922971
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00919278
TGFBI transforming growth factor, beta-induced, 68kDa 0.00916886
COL14A1 collagen, type XIV, alpha 1 0.00914842
PMP22 peripheral myelin protein 22 0.00914787
PLK2 polo-like kinase 2 0.00905744
SNAI2 snail family zinc finger 2 0.00902545
REG3A regenerating islet-derived 3 alpha 0.00897925
CTSK cathepsin K 0.00895011
TOX3 TOX high mobility group box family member 3 0.00889466
GEM GTP binding protein overexpressed in skeletal muscle 0.0088021
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00873335
CRYAB crystallin, alpha B 0.0086798
IFI6 interferon, alpha-inducible protein 6 0.00864071
TNS3 tensin 3 0.00863663
AREG amphiregulin 0.0085883
TGFBR3 transforming growth factor, beta receptor III 0.00846482
MT1X metallothionein 1X 0.008453
TAGLN transgelin 0.00842095
THBS1 thrombospondin 1 0.00833105
CCDC92 coiled-coil domain containing 92 0.00831745
APOD apolipoprotein D 0.00814202
RHOBTB3 Rho-related BTB domain containing 3 0.00806371
SIDT2 SID1 transmembrane family, member 2 0.00805125
GLRX2 glutaredoxin 2 0.00803413
AMIGO2 adhesion molecule with Ig-like domain 2 0.00801522
DUSP5 dual specificity phosphatase 5 0.00801162
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00800925
FBLN1 fibulin 1 0.00792215
EFNB2 ephrin-B2 0.00791164
CCL20 chemokine (C-C motif) ligand 20 0.00787424
LGALS1 lectin, galactoside-binding, soluble, 1 0.0078491
TACSTD2 tumor-associated calcium signal transducer 2 0.00782274
MMP7 matrix metallopeptidase 7 0.00780287
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00775156
JCHAIN joining chain of multimeric IgA and IgM 0.00774194
REG1A regenerating islet-derived 1 alpha 0.00772953
TIMP3 TIMP metallopeptidase inhibitor 3 0.00771702
MIR22HG MIR22 host gene 0.00768039
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00762758
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00759195
MMP1 matrix metallopeptidase 1 0.00754129
HIST1H2AC histone cluster 1, H2ac 0.00753392
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00753115
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00751338
JAG1 jagged 1 0.00750279
IL1RN interleukin 1 receptor antagonist 0.0074893
IFI27 interferon, alpha-inducible protein 27 0.0074636
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00745627
SFRP4 secreted frizzled-related protein 4 0.00737895
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00737772
GPX3 glutathione peroxidase 3 0.00736283
SRPX sushi-repeat containing protein, X-linked 0.00726906
CLGN calmegin 0.00722992
C10ORF10 chromosome 10 open reading frame 10 0.00722901
SYNM synemin, intermediate filament protein 0.00721983
CD9 CD9 molecule 0.00713719
MT1G metallothionein 1G 0.00713614
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.00708354
LMNA lamin A/C 0.0070822
C3 complement component 3 0.00706543
TRPS1 trichorhinophalangeal syndrome I 0.00706235
CKM creatine kinase, muscle 0.00706229
MXRA5 matrix-remodelling associated 5 0.00706055
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00705939
NPY1R neuropeptide Y receptor Y1 0.00702496
CCR1 chemokine (C-C motif) receptor 1 0.00702333
CCL4 chemokine (C-C motif) ligand 4 0.006988
HIST1H2BK histone cluster 1, H2bk 0.00697137
CFD complement factor D (adipsin) 0.00696239
HSPH1 heat shock 105kDa/110kDa protein 1 0.00695699
NOTCH2 notch 2 0.0069542
MITF microphthalmia-associated transcription factor 0.00694972
LIF leukemia inhibitory factor 0.00691809
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00688465
HMOX1 heme oxygenase 1 0.00688222
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00685647
PLIN2 perilipin 2 0.00682531
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00679574
LIPG lipase, endothelial 0.00677943
RIN2 Ras and Rab interactor 2 0.00674734
CCN2 cellular communication network factor 2 0.00672389
PDLIM4 PDZ and LIM domain 4 0.00670615
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00669986
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00669928
IDO1 indoleamine 2,3-dioxygenase 1 0.00667962
OLFM4 olfactomedin 4 0.00666142
LAMC2 laminin, gamma 2 0.00665849
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00665075
C8ORF4 chromosome 8 open reading frame 4 0.00663854
PDLIM5 PDZ and LIM domain 5 0.00662423
CNN3 calponin 3, acidic 0.00661167
COL16A1 collagen, type XVI, alpha 1 0.00658472
DYNLL1 dynein, light chain, LC8-type 1 0.00658162
PLAU plasminogen activator, urokinase 0.00657609
KRT19 keratin 19, type I 0.00657572
BIK BCL2-interacting killer (apoptosis-inducing) 0.00656274
MCAM melanoma cell adhesion molecule 0.00653533
MOSPD1 motile sperm domain containing 1 0.00651275
MAGED1 melanoma antigen family D1 0.00650724
SH3BP4 SH3-domain binding protein 4 0.00650437
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00649932
PDGFRL platelet-derived growth factor receptor-like 0.0064783
IL1B interleukin 1, beta 0.00647749
COL9A3 collagen, type IX, alpha 3 0.00645412
CD36 CD36 molecule (thrombospondin receptor) 0.00644217
TGM2 transglutaminase 2 0.00639962
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00637672
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00636355
MAPK6 mitogen-activated protein kinase 6 0.00634875
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00634841
PBX3 pre-B-cell leukemia homeobox 3 0.00634786
ADIRF adipogenesis regulatory factor 0.00634458
S100A2 S100 calcium binding protein A2 0.00633493
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00632251
MX1 MX dynamin-like GTPase 1 0.00631472
CHIC2 cysteine-rich hydrophobic domain 2 0.00630478
CCNA1 cyclin A1 0.00630084
CLCN4 chloride channel, voltage-sensitive 4 0.00629617
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00629199
IGFBP6 insulin-like growth factor binding protein 6 0.00626195
CXCL11 chemokine (C-X-C motif) ligand 11 0.00625161
SCPEP1 serine carboxypeptidase 1 0.00620734
DOCK4 dedicator of cytokinesis 4 0.00620112
MLPH melanophilin 0.00619585
TGIF1 TGFB-induced factor homeobox 1 0.00617481
RND3 Rho family GTPase 3 0.00616959
CD93 CD93 molecule 0.00616665
PEG10 paternally expressed 10 0.00616562
GSDME gasdermin E 0.00616551
GREM1 gremlin 1, DAN family BMP antagonist 0.00616218
G0S2 G0/G1 switch 2 0.00615818
NOTCH1 notch 1 0.00613967
ANKRD12 ankyrin repeat domain 12 0.00613364
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.00609974
LRRC17 leucine rich repeat containing 17 0.00609347
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00608989
KLHL21 kelch-like family member 21 0.00606803
H1-2 H1.2 linker histone, cluster member 0.0060529
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.0060491
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00603984
TUBB2A tubulin, beta 2A class IIa 0.00603648
QDPR quinoid dihydropteridine reductase 0.00601019
SDCBP syndecan binding protein (syntenin) 0.00600706
KRT17 keratin 17, type I 0.0060014
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00599401
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.00594875
IRS1 insulin receptor substrate 1 0.00593573
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00593432
NCAM1 neural cell adhesion molecule 1 0.00593136
GYG1 glycogenin 1 0.00592757
ZCCHC24 zinc finger, CCHC domain containing 24 0.00592559
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00592377
CCL8 chemokine (C-C motif) ligand 8 0.00591365
COL6A2 collagen, type VI, alpha 2 0.00591241
CAV1 caveolin 1, caveolae protein, 22kDa 0.00591205
LPAR6 lysophosphatidic acid receptor 6 0.00586369
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.0058491
IFI44L interferon-induced protein 44-like 0.00582442
COPS7A COP9 signalosome subunit 7A 0.00579794
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00578689
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00577695
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00577245
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00577044
HNMT histamine N-methyltransferase 0.00576826
CHN2 chimerin 2 0.00575361
CHRDL1 chordin-like 1 0.00574727
NELL1 NEL-like 1 (chicken) 0.00574334
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00574
FMOD fibromodulin 0.00571183
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00568134
PLAAT3 phospholipase A and acyltransferase 3 0.00566151
THBD thrombomodulin 0.00565233
MIA melanoma inhibitory activity 0.00564691
ZNF232 zinc finger protein 232 0.00564324
F3 coagulation factor III (thromboplastin, tissue factor) 0.00564233
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00564168
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00562986
TNNI2 troponin I type 2 (skeletal, fast) 0.00562879
GOLGA4 golgin A4 0.00561596
ARMCX3 armadillo repeat containing, X-linked 3 0.00560078
POSTN periostin, osteoblast specific factor 0.00559457
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.00558992
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00558329
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00558026
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00557616
LPXN leupaxin 0.00556145
PLD3 phospholipase D family, member 3 0.00555755
TSPAN4 tetraspanin 4 0.00555213
LY96 lymphocyte antigen 96 0.00554129
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00554104
INHBB inhibin, beta B 0.00552569
CD163 CD163 molecule 0.00552083
ALOX5 arachidonate 5-lipoxygenase 0.00551114
CXCL5 chemokine (C-X-C motif) ligand 5 0.005503
C1QB complement component 1, q subcomponent, B chain 0.00547056
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0054693
ITGAV integrin, alpha V 0.00546709
FXYD3 FXYD domain containing ion transport regulator 3 0.00546107
ACTA1 actin, alpha 1, skeletal muscle 0.00545735
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00545734
OSBPL10 oxysterol binding protein-like 10 0.00544576
ZNHIT6 zinc finger, HIT-type containing 6 0.00544335
MMP11 matrix metallopeptidase 11 0.00543973
AHNAK2 AHNAK nucleoprotein 2 0.00543472
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00541835
XIC X chromosome inactivation center 0.00541133
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00540355
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00539344
REXO2 RNA exonuclease 2 0.00537472
MED13 mediator complex subunit 13 0.00537258
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00536236
MFAP5 microfibrillar associated protein 5 0.00536039
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00535722
C1R complement component 1, r subcomponent 0.005342
HIST1H2BD histone cluster 1, H2bd 0.00533267
C1S complement component 1, s subcomponent 0.00532688
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00532669
ANGPTL2 angiopoietin-like 2 0.00530914
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.00530743
DPP4 dipeptidyl-peptidase 4 0.00530072
TBK1 TANK-binding kinase 1 0.00529162
OGN osteoglycin 0.00527594

decreased expression

Symbol Name Standardized Value
PSIP1 PC4 and SFRS1 interacting protein 1 -0.0138047
CA12 carbonic anhydrase XII -0.0123678
CIAO3 cytosolic iron-sulfur assembly component 3 -0.0118959
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.0101983
MAP7 microtubule-associated protein 7 -0.00981239
SLPI secretory leukocyte peptidase inhibitor -0.00942853
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00915397
RETREG1 reticulophagy regulator 1 -0.00850724
NELL2 NEL-like 2 (chicken) -0.0083893
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00834265
EMX2 empty spiracles homeobox 2 -0.00823577
GAL galanin/GMAP prepropeptide -0.00819033
AKAP8 A kinase (PRKA) anchor protein 8 -0.00811033
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00810868
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00808959
CA2 carbonic anhydrase II -0.0080588
HOXB7 homeobox B7 -0.00792139
SIRT3 sirtuin 3 -0.00789376
BIRC5 baculoviral IAP repeat containing 5 -0.00780352
CGA glycoprotein hormones, alpha polypeptide -0.00778995
SYT1 synaptotagmin I -0.0077156
SSBP2 single-stranded DNA binding protein 2 -0.00769572
GSTP1 glutathione S-transferase pi 1 -0.0075954
S100A9 S100 calcium binding protein A9 -0.00745006
S100A12 S100 calcium binding protein A12 -0.00733712
MUC4 mucin 4, cell surface associated -0.00723637
ASF1B anti-silencing function 1B histone chaperone -0.00721606
BEX1 brain expressed, X-linked 1 -0.00712654
DHFR dihydrofolate reductase -0.00710607
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00707494
PI3 peptidase inhibitor 3, skin-derived -0.0070376
ELANE elastase, neutrophil expressed -0.00699595
RHOB ras homolog family member B -0.00696404
BRCA1 breast cancer 1, early onset -0.00693043
HSPB1 heat shock 27kDa protein 1 -0.00690619
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00680619
RFC2 replication factor C (activator 1) 2, 40kDa -0.00679043
MPO myeloperoxidase -0.00678018
KIF20A kinesin family member 20A -0.00675577
FBXO11 F-box protein 11 -0.00671701
CCNA2 cyclin A2 -0.00671012
RASA4 RAS p21 protein activator 4 -0.00670476
LIG1 ligase I, DNA, ATP-dependent -0.00668586
SET SET nuclear proto-oncogene -0.00667074
DDR2 discoidin domain receptor tyrosine kinase 2 -0.0066704
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00662313
MKI67 marker of proliferation Ki-67 -0.0066059
SPC25 SPC25, NDC80 kinetochore complex component -0.00659475
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00657984
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00655113
AURKB aurora kinase B -0.00649868
TXN thioredoxin -0.00649512
TPM4 tropomyosin 4 -0.0064851
ELAVL1 ELAV like RNA binding protein 1 -0.00646201
CD200 CD200 molecule -0.00642646
CIT citron rho-interacting serine/threonine kinase -0.00641913
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00641091
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.006363
STX10 syntaxin 10 -0.00635749
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00635101
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00634951
FOLR1 folate receptor 1 (adult) -0.00632885
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.00632324
DNTT DNA nucleotidylexotransferase -0.00629194
NPTX2 neuronal pentraxin II -0.00628869
SPRR3 small proline-rich protein 3 -0.00623545
OIP5 Opa interacting protein 5 -0.00623456
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00622565
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00621404
FKBP5 FK506 binding protein 5 -0.0061886
AKR1C3 aldo-keto reductase family 1, member C3 -0.00614056
LARS1 leucyl-tRNA synthetase 1 -0.00613413
ZNF395 zinc finger protein 395 -0.00613184
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00612783
ARG1 arginase 1 -0.00612688
CSTA cystatin A (stefin A) -0.006113
CDT1 chromatin licensing and DNA replication factor 1 -0.00603348
IFRD2 interferon-related developmental regulator 2 -0.00601331
KIF23 kinesin family member 23 -0.00600704
OLFM1 olfactomedin 1 -0.00597477
RHCG Rh family, C glycoprotein -0.00590005
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00587286
HAUS4 HAUS augmin-like complex, subunit 4 -0.00583527
GYPC glycophorin C (Gerbich blood group) -0.0058325
CCNB2 cyclin B2 -0.00579116
NEFM neurofilament, medium polypeptide -0.00576902
HIGD2A HIG1 hypoxia inducible domain family, member 2A -0.0057459
MAL mal, T-cell differentiation protein -0.00572557
CHIT1 chitinase 1 (chitotriosidase) -0.00572538
KIF15 kinesin family member 15 -0.00570975
PGLYRP1 peptidoglycan recognition protein 1 -0.0056842
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00567399
HOXC6 homeobox C6 -0.00566553
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -0.00566406
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00565926
NCAPG2 non-SMC condensin II complex, subunit G2 -0.00565713
TRIM28 tripartite motif containing 28 -0.00564323
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00564311
GINS3 GINS complex subunit 3 (Psf3 homolog) -0.0056071
S100A7 S100 calcium binding protein A7 -0.00560322
GRAMD1B GRAM domain containing 1B -0.00559365
CCNG1 cyclin G1 -0.00558921
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00558699
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.0055679
CNPY3 canopy FGF signaling regulator 3 -0.00556418
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00552703
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00552632
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -0.00551663
INSR insulin receptor -0.00550296
TOX thymocyte selection-associated high mobility group box -0.00550099
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00548199
MNDA myeloid cell nuclear differentiation antigen -0.00546213
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00543899
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.00543625
PRSS21 protease, serine, 21 (testisin) -0.00542945
HIP1 huntingtin interacting protein 1 -0.00542857
FLOT2 flotillin 2 -0.00542349
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00539808
SNAP25 synaptosomal-associated protein, 25kDa -0.00538439
TRIP13 thyroid hormone receptor interactor 13 -0.00538082
ALDOA aldolase A, fructose-bisphosphate -0.00535691
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00535386
BAALC brain and acute leukemia, cytoplasmic -0.0053512
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00533759
AHCY adenosylhomocysteinase -0.00533701
LMNB1 lamin B1 -0.00533039
SPON1 spondin 1, extracellular matrix protein -0.00532371
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0053237
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00532236
SFTPB surfactant protein B -0.00532069
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00531057
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00530977
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.00530459
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.00528515
MECOM MDS1 and EVI1 complex locus -0.00526916
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00526635
RNASEH2A ribonuclease H2, subunit A -0.00525975
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0052463
FBXO5 F-box protein 5 -0.00524585
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00524317
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A -0.00522659
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00522324
WFDC2 WAP four-disulfide core domain 2 -0.00521986
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.0052004
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00520006
CLEC11A C-type lectin domain family 11, member A -0.0051991
HAL histidine ammonia-lyase -0.00519191
HBB hemoglobin, beta -0.00518259
EPHA1 EPH receptor A1 -0.00518036
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00516465
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -0.0051491
SPRR1A small proline-rich protein 1A -0.00514515
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00514107
STXBP2 syntaxin binding protein 2 -0.00513288
QPRT quinolinate phosphoribosyltransferase -0.0051231
GLTP glycolipid transfer protein -0.00511753
DEAF1 DEAF1 transcription factor -0.00511127
SYT17 synaptotagmin XVII -0.00510544
SFTPA2 surfactant protein A2 -0.00509824
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00506728
NREP neuronal regeneration related protein -0.00506727
TYRO3 TYRO3 protein tyrosine kinase -0.00505078
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00503658
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.0050304
PBK PDZ binding kinase -0.00502758
ADD3 adducin 3 (gamma) -0.00500437
PLIN3 perilipin 3 -0.0050038
NUSAP1 nucleolar and spindle associated protein 1 -0.00500238
P3H2 prolyl 3-hydroxylase 2 -0.00500094
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -0.0049906
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00497906
TRH thyrotropin-releasing hormone -0.00496976
MXD3 MAX dimerization protein 3 -0.00496404
PER1 period circadian clock 1 -0.00495567
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -0.00494424
ATP5PD ATP synthase peripheral stalk subunit d -0.00493581
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00493383
CBS cystathionine-beta-synthase -0.00493266
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00492965
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00492476
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.00492234
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00491564
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00490238
CDCA3 cell division cycle associated 3 -0.0048944
SPRR2B small proline-rich protein 2B -0.00488972
STMN1 stathmin 1 -0.00488313
GPSM3 G-protein signaling modulator 3 -0.00487674
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -0.00487494
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00486904
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00486463
NPR3 natriuretic peptide receptor 3 -0.00485298
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00485152
COL1A2 collagen, type I, alpha 2 -0.00484351
EDN3 endothelin 3 -0.00483662
GRAMD1C GRAM domain containing 1C -0.00482226
PRPF4 pre-mRNA processing factor 4 -0.00482128
E2F8 E2F transcription factor 8 -0.0048191
TRIM9 tripartite motif containing 9 -0.00481765
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00481526
UBXN7 UBX domain protein 7 -0.00480412
ECI1 enoyl-CoA delta isomerase 1 -0.00480333
KIF11 kinesin family member 11 -0.0048015
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.00479621
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00478249
FABP6 fatty acid binding protein 6, ileal -0.0047792
NHP2 NHP2 ribonucleoprotein -0.00477227
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00476669
MLF1 myeloid leukemia factor 1 -0.00475553
NRN1 neuritin 1 -0.00474922
RAD51 RAD51 recombinase -0.00474205
SFTPC surfactant protein C -0.00474024
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0047389
SEPP1 selenoprotein P, plasma, 1 -0.00473208
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00473028
C19ORF54 chromosome 19 open reading frame 54 -0.00472428
MRPS16 mitochondrial ribosomal protein S16 -0.00472247
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00472169
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00470854
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00470758
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00468757
MAPK14 mitogen-activated protein kinase 14 -0.00468336
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00467756
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00467596
SFXN1 sideroflexin 1 -0.00467132
NABP2 nucleic acid binding protein 2 -0.00467096
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -0.00466814
GAB2 GRB2-associated binding protein 2 -0.00466692
FAR2 fatty acyl CoA reductase 2 -0.00466675
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.00465037
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00464679
ACOX2 acyl-CoA oxidase 2, branched chain -0.00463906
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00463838
RBMX RNA binding motif protein, X-linked -0.00463501
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.0046282
ACOT13 acyl-CoA thioesterase 13 -0.00461063
LY75 lymphocyte antigen 75 -0.004609
TP53 tumor protein p53 -0.00460123
NCAPD2 non-SMC condensin I complex, subunit D2 -0.00460078
MSLN mesothelin -0.00460073
EIF4B eukaryotic translation initiation factor 4B -0.00458649
TESC tescalcin -0.00457941
CERS6 ceramide synthase 6 -0.00457423
CCDC28B coiled-coil domain containing 28B -0.00456995
PCLAF PCNA clamp associated factor -0.00455819
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.00455147
ABHD11 abhydrolase domain containing 11 -0.00454407
PUF60 poly-U binding splicing factor 60KDa -0.00453612
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00453204
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00452477
CCNF cyclin F -0.00452392