CHD7 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chromodomain helicase DNA binding protein 7|This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55636)
External Link https://ncbi.nlm.nih.gov/gene/55636
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Genes

498 genes differentially expressed following the CHD7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0139504
IFI44L interferon-induced protein 44-like 0.0138915
MX1 MX dynamin-like GTPase 1 0.0127991
PLK2 polo-like kinase 2 0.0121399
ISG15 ISG15 ubiquitin-like modifier 0.0114753
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0113172
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0113164
S100A9 S100 calcium binding protein A9 0.011053
RSAD2 radical S-adenosyl methionine domain containing 2 0.0110356
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0109605
COG7 component of oligomeric golgi complex 7 0.0109272
ANXA1 annexin A1 0.0107112
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0104257
LITAF lipopolysaccharide-induced TNF factor 0.0103356
TRIM22 tripartite motif containing 22 0.00996052
TACSTD2 tumor-associated calcium signal transducer 2 0.00986728
S100A8 S100 calcium binding protein A8 0.00978015
CXCL8 chemokine (C-X-C motif) ligand 8 0.00932791
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00932759
S100A10 S100 calcium binding protein A10 0.00926789
GNAS GNAS complex locus 0.00924326
FABP4 fatty acid binding protein 4, adipocyte 0.00924322
BAMBI BMP and activin membrane-bound inhibitor 0.00918711
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00888114
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00885021
FXYD3 FXYD domain containing ion transport regulator 3 0.00873665
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.008706
TUBB2A tubulin, beta 2A class IIa 0.00867669
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00860861
DEFB1 defensin, beta 1 0.00850129
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00839021
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0083734
KDM3A lysine (K)-specific demethylase 3A 0.00837121
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00835248
IFI6 interferon, alpha-inducible protein 6 0.00832941
ADM adrenomedullin 0.00827019
MYO1B myosin IB 0.00824976
STOM stomatin 0.00819129
CXCL12 chemokine (C-X-C motif) ligand 12 0.0080697
KYNU kynureninase 0.00795989
ADIRF adipogenesis regulatory factor 0.00793609
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00787532
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00784215
TFRC transferrin receptor 0.00780588
S100A7 S100 calcium binding protein A7 0.00771038
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00770551
RND3 Rho family GTPase 3 0.00768441
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0076266
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0076104
FN1 fibronectin 1 0.00759618
AREG amphiregulin 0.00751411
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00748022
TRIM29 tripartite motif containing 29 0.00747067
ANXA2P2 annexin A2 pseudogene 2 0.00737154
CA2 carbonic anhydrase II 0.0073709
TM4SF1 transmembrane 4 L six family member 1 0.00726288
LCN2 lipocalin 2 0.00723975
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00717629
ATF3 activating transcription factor 3 0.00708382
SPRR3 small proline-rich protein 3 0.00705786
MGLL monoglyceride lipase 0.00704287
LHFP lipoma HMGIC fusion partner 0.00703089
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00701706
MCL1 myeloid cell leukemia 1 0.00699246
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00698299
CD59 CD59 molecule, complement regulatory protein 0.00697423
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00696404
CAST calpastatin 0.00694352
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00691743
NCOA3 nuclear receptor coactivator 3 0.0069118
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00688611
CRABP1 cellular retinoic acid binding protein 1 0.0068602
XAF1 XIAP associated factor 1 0.00684726
KRT23 keratin 23, type I 0.0068002
OAT ornithine aminotransferase 0.00679733
TBX2 T-box 2 0.00674846
IFI44 interferon-induced protein 44 0.00671604
GUSBP3 glucuronidase, beta pseudogene 3 0.00670867
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00669958
ABLIM1 actin binding LIM protein 1 0.00667766
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.00664389
SELL selectin L 0.0066401
PI3 peptidase inhibitor 3, skin-derived 0.00663794
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.00663588
LAMP3 lysosomal-associated membrane protein 3 0.00662887
TRIB2 tribbles pseudokinase 2 0.0066162
ACKR3 atypical chemokine receptor 3 0.00660837
DAXX death-domain associated protein 0.00658369
EMP1 epithelial membrane protein 1 0.0065567
XIC X chromosome inactivation center 0.00654156
IL1RN interleukin 1 receptor antagonist 0.00652792
IFIH1 interferon induced with helicase C domain 1 0.00645471
SGK1 serum/glucocorticoid regulated kinase 1 0.00642487
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00641546
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00640815
NPY1R neuropeptide Y receptor Y1 0.00640744
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00639269
RIPK2 receptor-interacting serine-threonine kinase 2 0.00635783
KLF2 Kruppel-like factor 2 0.00634219
NT5E 5'-nucleotidase, ecto (CD73) 0.00633239
KRT13 keratin 13, type I 0.00631726
DYNLL1 dynein, light chain, LC8-type 1 0.00630093
FGF1 fibroblast growth factor 1 (acidic) 0.00628137
KRT5 keratin 5, type II 0.00627805
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00619112
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00615543
TUBB6 tubulin, beta 6 class V 0.00607506
ADD3 adducin 3 (gamma) 0.00607188
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00606558
CSTA cystatin A (stefin A) 0.00605868
IER5 immediate early response 5 0.0060514
TMEM140 transmembrane protein 140 0.00604623
IFITM1 interferon induced transmembrane protein 1 0.00601833
CLEC3B C-type lectin domain family 3, member B 0.0059916
BSDC1 BSD domain containing 1 0.0059856
DNM1L dynamin 1-like 0.00596495
NMRK1 nicotinamide riboside kinase 1 0.00595298
CFB complement factor B 0.0059526
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00594975
KRT15 keratin 15, type I 0.00593418
THBS1 thrombospondin 1 0.00592534
MIR22HG MIR22 host gene 0.00591792
ISG20 interferon stimulated exonuclease gene 20kDa 0.00589658
HSPA1A heat shock 70kDa protein 1A 0.00587844
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00585305
CD58 CD58 molecule 0.00582991
CSRP2 cysteine and glycine-rich protein 2 0.00580336
TPBG trophoblast glycoprotein 0.00580112
GPM6B glycoprotein M6B 0.00576656
ASS1 argininosuccinate synthase 1 0.00576341
EFHD1 EF-hand domain family, member D1 0.00574212
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00573154
HLA-F major histocompatibility complex, class I, F 0.00572383
NIBAN1 niban apoptosis regulator 1 0.00570932
ASXL2 additional sex combs like transcriptional regulator 2 0.00570894
CCNG1 cyclin G1 0.00570125
HLA-B major histocompatibility complex, class I, B 0.00569269
CLINT1 clathrin interactor 1 0.00567469
TMEM255A transmembrane protein 255A 0.0056737
SLPI secretory leukocyte peptidase inhibitor 0.00564513
LGMN legumain 0.0056405
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00562994
CTSD cathepsin D 0.00561157
DUSP5 dual specificity phosphatase 5 0.0056019
PRPF4 pre-mRNA processing factor 4 0.00559072
PPL periplakin 0.00558323
RAB9A RAB9A, member RAS oncogene family 0.00557791
ANXA2 annexin A2 0.00556532
OSBPL9 oxysterol binding protein-like 9 0.00556072
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00554495
PSIP1 PC4 and SFRS1 interacting protein 1 0.00553019
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00552925
SAT1 spermidine/spermine N1-acetyltransferase 1 0.0055152
HMBOX1 homeobox containing 1 0.00551236
ZNF512B zinc finger protein 512B 0.00551202
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00551143
LXN latexin 0.00549215
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00549127
SH3YL1 SH3 and SYLF domain containing 1 0.00548276
LPAR6 lysophosphatidic acid receptor 6 0.00548255
MX2 MX dynamin-like GTPase 2 0.00547108
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00544805
PELI1 pellino E3 ubiquitin protein ligase 1 0.0054468
YPEL5 yippee-like 5 (Drosophila) 0.00544299
VCL vinculin 0.00542179
GPNMB glycoprotein (transmembrane) nmb 0.00541388
IRF9 interferon regulatory factor 9 0.00540038
ERAP1 endoplasmic reticulum aminopeptidase 1 0.00539907
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00535056
KRT19 keratin 19, type I 0.00532932
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00532698
AHR aryl hydrocarbon receptor 0.00531494
MSMO1 methylsterol monooxygenase 1 0.00530118
PTPRK protein tyrosine phosphatase, receptor type, K 0.00529956
AQP3 aquaporin 3 (Gill blood group) 0.00529456
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00528038
KRT14 keratin 14, type I 0.00527353
PLS3 plastin 3 0.00524604
STX3 syntaxin 3 0.00524318
SP110 SP110 nuclear body protein 0.00524007
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00523441
TTC9 tetratricopeptide repeat domain 9 0.00523002
OSER1 oxidative stress responsive serine-rich 1 0.00522432
LPAR1 lysophosphatidic acid receptor 1 0.00522116
ZNF652 zinc finger protein 652 0.00520473
SP140L SP140 nuclear body protein-like 0.00520383
C3ORF14 chromosome 3 open reading frame 14 0.00519403
GRB7 growth factor receptor-bound protein 7 0.00518893
RAP1B RAP1B, member of RAS oncogene family 0.00517875
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00516558
AKR1C2 aldo-keto reductase family 1, member C2 0.00516282
WISP2 WNT1 inducible signaling pathway protein 2 0.00515962
GATA3 GATA binding protein 3 0.00515417
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00514552
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00512308
JAG1 jagged 1 0.00511667
ZC3H12A zinc finger CCCH-type containing 12A 0.00510928
MT1E metallothionein 1E 0.00510548
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00510268
TLR4 toll-like receptor 4 0.00510232
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00508738
C1ORF54 chromosome 1 open reading frame 54 0.00508477
KLF6 Kruppel-like factor 6 0.00507635
TCTA T-cell leukemia translocation altered 0.00505879
HBB hemoglobin, beta 0.00504718
CRYBG1 crystallin beta-gamma domain containing 1 0.00502887
PXDN peroxidasin 0.00501774
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00501678
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00500602
IFNGR1 interferon gamma receptor 1 0.00499517
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00499302
RRAGD Ras-related GTP binding D 0.00499177
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00498709
CD52 CD52 molecule 0.00498008
TRIM14 tripartite motif containing 14 0.0049772
THBS2 thrombospondin 2 0.00496606
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00495582
STC2 stanniocalcin 2 0.0049499
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00493722
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00493495
SP100 SP100 nuclear antigen 0.00491518
CHI3L2 chitinase 3-like 2 0.00491166
OXA1L oxidase (cytochrome c) assembly 1-like 0.00491149
PBX3 pre-B-cell leukemia homeobox 3 0.00490862
CTSS cathepsin S 0.00488704
CES1 carboxylesterase 1 0.00488651
HLA-C major histocompatibility complex, class I, C 0.00488377
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00487423
PLSCR1 phospholipid scramblase 1 0.00485554
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00483727
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00483147
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00482937
EIF5A eukaryotic translation initiation factor 5A 0.00481152
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00479848
DCN decorin 0.00479005
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00477111
TJP2 tight junction protein 2 0.00476487
ZMAT3 zinc finger, matrin-type 3 0.00476239
TLE4 transducin-like enhancer of split 4 0.00475133
FRMD4B FERM domain containing 4B 0.00474339
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0047386
C2CD2 C2 calcium-dependent domain containing 2 0.00473278
HBD hemoglobin, delta 0.00473167
JCHAIN joining chain of multimeric IgA and IgM 0.00472992
ARMCX1 armadillo repeat containing, X-linked 1 0.00472582
PDZD2 PDZ domain containing 2 0.00471196
PTHLH parathyroid hormone-like hormone 0.00470067
CAV2 caveolin 2 0.00469731
TSC22D2 TSC22 domain family, member 2 0.00469513
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00469432

decreased expression

Symbol Name Standardized Value
PCP4 Purkinje cell protein 4 -0.00982629
CD320 CD320 molecule -0.00975177
STXBP2 syntaxin binding protein 2 -0.00966189
TFF3 trefoil factor 3 (intestinal) -0.00952931
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00915838
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00875257
SEPP1 selenoprotein P, plasma, 1 -0.0083887
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00814125
CHKB choline kinase beta -0.00773031
CDC20 cell division cycle 20 -0.00763944
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00731593
HOXB6 homeobox B6 -0.0072844
CST3 cystatin C -0.00714435
BCHE butyrylcholinesterase -0.00711946
NUSAP1 nucleolar and spindle associated protein 1 -0.00708881
AGR2 anterior gradient 2 -0.00696151
APMAP adipocyte plasma membrane associated protein -0.00693924
COQ8A coenzyme Q8A -0.00681735
TXNIP thioredoxin interacting protein -0.00671112
BIRC5 baculoviral IAP repeat containing 5 -0.00670483
E2F2 E2F transcription factor 2 -0.00653503
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00652266
TPSAB1 tryptase alpha/beta 1 -0.00651814
ZBTB18 zinc finger and BTB domain containing 18 -0.00646578
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00643638
TSPAN8 tetraspanin 8 -0.00631088
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00623084
CNPY3 canopy FGF signaling regulator 3 -0.00622041
KIF20A kinesin family member 20A -0.00619165
TPI1 triosephosphate isomerase 1 -0.00617579
KDM5D lysine (K)-specific demethylase 5D -0.0061454
PTH2R parathyroid hormone 2 receptor -0.00608069
CALCA calcitonin-related polypeptide alpha -0.00607997
TMEM106C transmembrane protein 106C -0.00597434
EFHD2 EF-hand domain family, member D2 -0.00585725
NDRG1 N-myc downstream regulated 1 -0.0057937
SPARCL1 SPARC-like 1 (hevin) -0.005744
NNMT nicotinamide N-methyltransferase -0.00569446
PRUNE1 prune exopolyphosphatase 1 -0.00568976
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00561123
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00560298
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.0055926
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00557953
PIMREG PICALM interacting mitotic regulator -0.00557249
TMEM176A transmembrane protein 176A -0.0055658
TMEM176B transmembrane protein 176B -0.00555561
GLUL glutamate-ammonia ligase -0.00553432
COPS7A COP9 signalosome subunit 7A -0.0055197
SFTPB surfactant protein B -0.00548116
PGC progastricsin (pepsinogen C) -0.00546222
RNASEH2A ribonuclease H2, subunit A -0.00539564
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00539068
NMU neuromedin U -0.00537369
YEATS4 YEATS domain containing 4 -0.00536102
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00534855
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00532838
CIT citron rho-interacting serine/threonine kinase -0.00531505
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -0.00529441
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00526627
WT1 Wilms tumor 1 -0.0052607
LMNB2 lamin B2 -0.00525296
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00516154
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0050929
DLK1 delta-like 1 homolog (Drosophila) -0.00509253
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00507937
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00507696
RHOA ras homolog family member A -0.00507412
CEP55 centrosomal protein 55kDa -0.00507283
TGFB1 transforming growth factor, beta 1 -0.00505183
ASF1B anti-silencing function 1B histone chaperone -0.00504594
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00503764
TBCD tubulin folding cofactor D -0.00503533
DES desmin -0.00503027
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00499511
MAGEA3 melanoma antigen family A3 -0.00494649
CRLF1 cytokine receptor-like factor 1 -0.00494073
SUB1 SUB1 homolog (S. cerevisiae) -0.00493432
MCM5 minichromosome maintenance complex component 5 -0.00493154
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.00492246
CDT1 chromatin licensing and DNA replication factor 1 -0.00490663
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00488705
GRB14 growth factor receptor-bound protein 14 -0.00488162
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00487905
TOP2A topoisomerase (DNA) II alpha 170kDa -0.00485015
SMTN smoothelin -0.00484768
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00483448
XAB2 XPA binding protein 2 -0.0048317
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00481804
AURKB aurora kinase B -0.00480607
CCNB2 cyclin B2 -0.00480296
NINJ2 ninjurin 2 -0.00478288
COL6A2 collagen, type VI, alpha 2 -0.00478272
CTSZ cathepsin Z -0.0047791
NRGN neurogranin (protein kinase C substrate, RC3) -0.00477428
COMP cartilage oligomeric matrix protein -0.00476227
PNPLA6 patatin-like phospholipase domain containing 6 -0.00475968
MAMLD1 mastermind-like domain containing 1 -0.00475079
PMF1 polyamine-modulated factor 1 -0.00474598
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00473416
NECTIN3 nectin cell adhesion molecule 3 -0.00472438
CCL21 chemokine (C-C motif) ligand 21 -0.00472266
RAB20 RAB20, member RAS oncogene family -0.00471469
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00466255
TECR trans-2,3-enoyl-CoA reductase -0.00465732
NUCB1 nucleobindin 1 -0.00463166
DSP desmoplakin -0.00461752
HMGB3 high mobility group box 3 -0.0046019
KLHDC3 kelch domain containing 3 -0.00460156
MMP2 matrix metallopeptidase 2 -0.00459944
PRR15L proline rich 15-like -0.00459879
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00459408
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00458927
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00458519
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00457675
CNOT3 CCR4-NOT transcription complex, subunit 3 -0.00457408
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00456873
GSTA4 glutathione S-transferase alpha 4 -0.00455951
WDR7 WD repeat domain 7 -0.00454988
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00454498
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00454003
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00453077
NTS neurotensin -0.00453075
TLN1 talin 1 -0.00451751
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00451511
UBE2S ubiquitin-conjugating enzyme E2S -0.00450877
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.00448312
CALR calreticulin -0.00447116
FXYD6 FXYD domain containing ion transport regulator 6 -0.00447066
SFTPA2 surfactant protein A2 -0.00446939
TARDBP TAR DNA binding protein -0.00445673
VWA1 von Willebrand factor A domain containing 1 -0.00445432
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00442596
MAOA monoamine oxidase A -0.00442528
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00441071
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00438801
SF3B4 splicing factor 3b, subunit 4, 49kDa -0.00437791
HDGF hepatoma-derived growth factor -0.00436986
PUF60 poly-U binding splicing factor 60KDa -0.00435724
NEK2 NIMA-related kinase 2 -0.00434929
PGAM1 phosphoglycerate mutase 1 (brain) -0.00433602
CDCA3 cell division cycle associated 3 -0.00432934
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0043241
PAEP progestagen-associated endometrial protein -0.00432054
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00428787
CENPB centromere protein B, 80kDa -0.00428144
MSLN mesothelin -0.00426854
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00426726
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00426217
TRIP13 thyroid hormone receptor interactor 13 -0.00425752
PKN1 protein kinase N1 -0.00424926
FASN fatty acid synthase -0.00424403
PFKL phosphofructokinase, liver -0.00424286
FLOT1 flotillin 1 -0.00424254
C20ORF27 chromosome 20 open reading frame 27 -0.00424136
RRBP1 ribosome binding protein 1 -0.0042387
PTMS parathymosin -0.00423148
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -0.00423121
RAB33A RAB33A, member RAS oncogene family -0.00423099
RAD23A RAD23 homolog A (S. cerevisiae) -0.00421715
RAPSN receptor-associated protein of the synapse -0.00421254
TYMS thymidylate synthetase -0.00420864
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00419987
GNPAT glyceronephosphate O-acyltransferase -0.00419505
DVL1 dishevelled segment polarity protein 1 -0.00418854
PRKCZ protein kinase C, zeta -0.00418247
CD1E CD1e molecule -0.00418233
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00416214
NPTX2 neuronal pentraxin II -0.00415913
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00415373
C7 complement component 7 -0.00415199
KLHDC2 kelch domain containing 2 -0.00414998
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00414978
TMEM14A transmembrane protein 14A -0.00414844
LOXL1 lysyl oxidase-like 1 -0.00414394
NOVA1 neuro-oncological ventral antigen 1 -0.00414327
ARRB2 arrestin, beta 2 -0.00414265
CCL19 chemokine (C-C motif) ligand 19 -0.00413958
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.00413063
ABHD14A abhydrolase domain containing 14A -0.00412857
LIG1 ligase I, DNA, ATP-dependent -0.00410015
ENO3 enolase 3 (beta, muscle) -0.004097
PSPH phosphoserine phosphatase -0.00409
MAT2A methionine adenosyltransferase II, alpha -0.00408477
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00406648
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00406031
TTC3 tetratricopeptide repeat domain 3 -0.00405008
TRIM28 tripartite motif containing 28 -0.00404646
SAC3D1 SAC3 domain containing 1 -0.00403506
NKX2-1 NK2 homeobox 1 -0.00402978
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00402931
TAGLN transgelin -0.00401519
ENO2 enolase 2 (gamma, neuronal) -0.00401212
INTS1 integrator complex subunit 1 -0.00400773
LMNB1 lamin B1 -0.00399493
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00398519
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0039829
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00398256
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00397912
PRRC2A proline-rich coiled-coil 2A -0.00397305
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00396776
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00396768
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00395428
FOXM1 forkhead box M1 -0.00394683
POMZP3 POM121 and ZP3 fusion -0.00394442
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00393982
FOLR1 folate receptor 1 (adult) -0.00393391
FASTKD3 FAST kinase domains 3 -0.00392519
OIP5 Opa interacting protein 5 -0.003916
EXOSC7 exosome component 7 -0.00391496
ADCY2 adenylate cyclase 2 (brain) -0.00391226
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00390948
VIL1 villin 1 -0.00390414
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00389505
NSG1 neuron specific gene family member 1 -0.00388929
FOXE1 forkhead box E1 -0.00388492
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.00388206
MAGEA12 melanoma antigen family A12 -0.00388153
COL6A1 collagen, type VI, alpha 1 -0.00386867
DEK DEK proto-oncogene -0.00386668
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00386533
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.00386266
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.0038624
IGFBP4 insulin-like growth factor binding protein 4 -0.00385134
SFTPC surfactant protein C -0.00385018
CST4 cystatin S -0.00384793
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.00384521
FLJ22184 -0.00384463
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.00384294
THAP7 THAP domain containing 7 -0.00384137
TIPRL TOR signaling pathway regulator -0.00383611
IGFBP1 insulin-like growth factor binding protein 1 -0.0038336
THOC6 THO complex 6 -0.00383318
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00383285
KRT2 keratin 2, type II -0.00383247
STX1A syntaxin 1A (brain) -0.00382848
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -0.00382051
BRD4 bromodomain containing 4 -0.00381193
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -0.00380695
GRK2 G protein-coupled receptor kinase 2 -0.00380359
COL18A1 collagen, type XVIII, alpha 1 -0.00379171
PMM1 phosphomannomutase 1 -0.0037865
HMGB1 high mobility group box 1 -0.00378275
CAMK1 calcium/calmodulin-dependent protein kinase I -0.0037821
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.003781
PLD3 phospholipase D family, member 3 -0.00377707
TMSB15A thymosin beta 15a -0.00376361
CENPM centromere protein M -0.00375238
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00374551