| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | conserved helix-loop-helix ubiquitous kinase|This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1147) |
| External Link | https://ncbi.nlm.nih.gov/gene/1147 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CHUK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0155369 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.014374 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0141996 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0122098 |
| THBS1 | thrombospondin 1 | 0.0115502 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0109809 |
| PEG10 | paternally expressed 10 | 0.0108414 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.0107376 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0102814 |
| NXN | nucleoredoxin | 0.00996312 |
| PLIN1 | perilipin 1 | 0.00988043 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00986589 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00984822 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00980869 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00965484 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00939861 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00933606 |
| MECOM | MDS1 and EVI1 complex locus | 0.0092803 |
| FBLN1 | fibulin 1 | 0.00924195 |
| CIDEC | cell death-inducing DFFA-like effector c | 0.00920233 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00910413 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00905501 |
| MEIS2 | Meis homeobox 2 | 0.0090188 |
| REG1A | regenerating islet-derived 1 alpha | 0.00881291 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00859062 |
| ASPH | aspartate beta-hydroxylase | 0.00845495 |
| ODC1 | ornithine decarboxylase 1 | 0.00844253 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0084382 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00840623 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00830719 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00829746 |
| SST | somatostatin | 0.00829621 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00807663 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00792199 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00787808 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00781971 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00767201 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00761105 |
| RGS4 | regulator of G-protein signaling 4 | 0.00746044 |
| L1CAM | L1 cell adhesion molecule | 0.00731534 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0072354 |
| MAOA | monoamine oxidase A | 0.00722793 |
| ASPN | asporin | 0.00721733 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00719437 |
| ADIRF | adipogenesis regulatory factor | 0.00718321 |
| BICC1 | BicC family RNA binding protein 1 | 0.00714641 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00713684 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00711074 |
| ABHD3 | abhydrolase domain containing 3 | 0.00709471 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00708802 |
| HTRA1 | HtrA serine peptidase 1 | 0.00699996 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00697086 |
| AXL | AXL receptor tyrosine kinase | 0.00696967 |
| ACKR3 | atypical chemokine receptor 3 | 0.00692875 |
| JAG1 | jagged 1 | 0.0068357 |
| GLS | glutaminase | 0.0068145 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00679971 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00677013 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00674508 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00671308 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.0066889 |
| STXBP2 | syntaxin binding protein 2 | 0.00667328 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00659948 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00656464 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00656299 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00656073 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00655241 |
| CPE | carboxypeptidase E | 0.00653101 |
| CD200 | CD200 molecule | 0.00652689 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00647921 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0064534 |
| RTN1 | reticulon 1 | 0.00641179 |
| FST | follistatin | 0.00641073 |
| MAGEA3 | melanoma antigen family A3 | 0.00640415 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00639138 |
| MIR22HG | MIR22 host gene | 0.00639054 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00638129 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00637905 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0063453 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00634054 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.0063232 |
| SGCE | sarcoglycan, epsilon | 0.00631829 |
| FZD6 | frizzled class receptor 6 | 0.00630978 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00628595 |
| PFN2 | profilin 2 | 0.00628102 |
| PLN | phospholamban | 0.00627701 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00626995 |
| EVI2A | ecotropic viral integration site 2A | 0.00626682 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00623942 |
| FAM13A | family with sequence similarity 13, member A | 0.00623936 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00622139 |
| STK39 | serine threonine kinase 39 | 0.00616274 |
| CLGN | calmegin | 0.00607783 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00607399 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00607282 |
| HES1 | hes family bHLH transcription factor 1 | 0.00607062 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00604464 |
| LOXL2 | lysyl oxidase-like 2 | 0.00603191 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00601894 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00599705 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00598782 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00593645 |
| PDGFC | platelet derived growth factor C | 0.00592419 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00591674 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00591471 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00586203 |
| CCN3 | cellular communication network factor 3 | 0.00583297 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00583122 |
| DCT | dopachrome tautomerase | 0.00583042 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00580403 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00576437 |
| CBX6 | chromobox homolog 6 | 0.00575047 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00574644 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00572612 |
| MDFIC | MyoD family inhibitor domain containing | 0.00571895 |
| LAMA5 | laminin, alpha 5 | 0.00569267 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00567235 |
| PRKCI | protein kinase C, iota | 0.00567107 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00566637 |
| PMP22 | peripheral myelin protein 22 | 0.0056599 |
| BBX | bobby sox homolog (Drosophila) | 0.0056277 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0056091 |
| FADS3 | fatty acid desaturase 3 | 0.00560187 |
| CIDEA | cell death-inducing DFFA-like effector a | 0.00553464 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0055111 |
| WTAP | Wilms tumor 1 associated protein | 0.00550798 |
| COMP | cartilage oligomeric matrix protein | 0.00550148 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00547947 |
| MITF | microphthalmia-associated transcription factor | 0.00546415 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00545896 |
| PLS3 | plastin 3 | 0.00544703 |
| PCP4 | Purkinje cell protein 4 | 0.00544356 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00544192 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00544074 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00542377 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00540188 |
| CTSA | cathepsin A | 0.00540187 |
| SV2B | synaptic vesicle glycoprotein 2B | 0.00539943 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00539397 |
| ATG2A | autophagy related 2A | 0.00537234 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00536524 |
| MFAP5 | microfibrillar associated protein 5 | 0.00536501 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00535724 |
| MYO1B | myosin IB | 0.00534787 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00533888 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00533588 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00532226 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00528484 |
| MXRA8 | matrix-remodelling associated 8 | 0.00527292 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00527033 |
| ANGPTL2 | angiopoietin-like 2 | 0.00525385 |
| ELN | elastin | 0.00525018 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00524399 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00524333 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00523767 |
| USP3 | ubiquitin specific peptidase 3 | 0.00523206 |
| EGR1 | early growth response 1 | 0.00522712 |
| GPX2 | glutathione peroxidase 2 | 0.0052172 |
| IRS1 | insulin receptor substrate 1 | 0.00521659 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00521572 |
| RPS27L | ribosomal protein S27-like | 0.00521361 |
| IFT57 | intraflagellar transport 57 | 0.00520458 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00520254 |
| ANXA4 | annexin A4 | 0.00520014 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00518143 |
| CD2AP | CD2-associated protein | 0.00517428 |
| FGL2 | fibrinogen-like 2 | 0.00517126 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00514755 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.00513328 |
| IPO13 | importin 13 | 0.00512065 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00511831 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00511611 |
| CERK | ceramide kinase | 0.00510102 |
| HDAC9 | histone deacetylase 9 | 0.00509282 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0050927 |
| DGKA | diacylglycerol kinase, alpha 80kDa | 0.00507857 |
| CFB | complement factor B | 0.00506907 |
| FN1 | fibronectin 1 | 0.00506887 |
| TSPAN14 | tetraspanin 14 | 0.00505977 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00504958 |
| MMD | monocyte to macrophage differentiation-associated | 0.00504354 |
| NBEA | neurobeachin | 0.00504318 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00503549 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00503466 |
| CCNA2 | cyclin A2 | 0.005024 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00501927 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00501898 |
| CCNG2 | cyclin G2 | 0.00500958 |
| GAS6 | growth arrest-specific 6 | 0.00500843 |
| TMEM165 | transmembrane protein 165 | 0.00500752 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.00500097 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00497098 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00496342 |
| NNMT | nicotinamide N-methyltransferase | 0.00495744 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00495426 |
| TMEM164 | transmembrane protein 164 | 0.00494725 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00490978 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00490003 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00489532 |
| TRABD | TraB domain containing | 0.00488229 |
| SVIL | supervillin | 0.00488053 |
| HOXD1 | homeobox D1 | 0.00486705 |
| TRIM8 | tripartite motif containing 8 | 0.00485402 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00482094 |
| PLTP | phospholipid transfer protein | 0.00482043 |
| PRB3 | proline-rich protein BstNI subfamily 3 | 0.00481144 |
| NPTX1 | neuronal pentraxin I | 0.0047941 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.00479164 |
| G0S2 | G0/G1 switch 2 | 0.00478417 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00478103 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00477867 |
| BTBD1 | BTB (POZ) domain containing 1 | 0.00477819 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.00477805 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | 0.00477393 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00476996 |
| GNAS | GNAS complex locus | 0.00476721 |
| ATP9A | ATPase, class II, type 9A | 0.00476445 |
| ACAN | aggrecan | 0.00475984 |
| CNN3 | calponin 3, acidic | 0.00475559 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00474551 |
| LAMB1 | laminin, beta 1 | 0.00474271 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00474172 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00473303 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00472848 |
| GSN | gelsolin | 0.00472836 |
| PLEC | plectin | 0.00472355 |
| PDE10A | phosphodiesterase 10A | 0.00472299 |
| SC5D | sterol-C5-desaturase | 0.00471453 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.0047136 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00470903 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00470262 |
| CALD1 | caldesmon 1 | 0.00469387 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00468809 |
| TMEM14B | transmembrane protein 14B | 0.00465914 |
| CD4 | CD4 molecule | 0.0046573 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00465381 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00464989 |
| RIN2 | Ras and Rab interactor 2 | 0.00464919 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00464736 |
| HK2 | hexokinase 2 | 0.00464469 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response | 0.00464441 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00464385 |
| WDR3 | WD repeat domain 3 | 0.0046321 |
| PNPLA2 | patatin-like phospholipase domain containing 2 | 0.00462316 |
| PMEL | premelanosome protein | 0.00461957 |
| LIMD2 | LIM domain containing 2 | 0.00461583 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00460855 |
| PLXNC1 | plexin C1 | 0.00460851 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00460512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FABP7 | fatty acid binding protein 7, brain | -0.0154013 |
| HOPX | HOP homeobox | -0.0150222 |
| LTF | lactotransferrin | -0.0144194 |
| MAP7 | microtubule-associated protein 7 | -0.01349 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0128058 |
| CHI3L2 | chitinase 3-like 2 | -0.0120436 |
| NEBL | nebulette | -0.011719 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.0112841 |
| TCTA | T-cell leukemia translocation altered | -0.0107459 |
| RBM34 | RNA binding motif protein 34 | -0.0107081 |
| FBXO11 | F-box protein 11 | -0.0105188 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.0104309 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.010359 |
| MYBPC1 | myosin binding protein C, slow type | -0.00990683 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00969866 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00935196 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00932701 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0091344 |
| OLFM1 | olfactomedin 1 | -0.00909396 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00907251 |
| RNF167 | ring finger protein 167 | -0.00906437 |
| ITM2A | integral membrane protein 2A | -0.00891325 |
| NES | nestin | -0.00891122 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00871191 |
| S100P | S100 calcium binding protein P | -0.00866846 |
| ANXA6 | annexin A6 | -0.0085962 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00846998 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00844533 |
| S100A7 | S100 calcium binding protein A7 | -0.00838724 |
| KLK6 | kallikrein-related peptidase 6 | -0.00835617 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00830381 |
| GPM6B | glycoprotein M6B | -0.0082413 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00820528 |
| TFF1 | trefoil factor 1 | -0.00797211 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00795246 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00794639 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0079158 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0079111 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00789689 |
| GPM6A | glycoprotein M6A | -0.00786797 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00785944 |
| IL20RA | interleukin 20 receptor, alpha | -0.00784289 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00779955 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00779366 |
| PMP2 | peripheral myelin protein 2 | -0.0076659 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00765076 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00759902 |
| PDZK1 | PDZ domain containing 1 | -0.0075944 |
| NKX2-2 | NK2 homeobox 2 | -0.00758544 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.0075684 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00750115 |
| CLIC3 | chloride intracellular channel 3 | -0.00734278 |
| COL3A1 | collagen, type III, alpha 1 | -0.00733862 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00733668 |
| SELL | selectin L | -0.00733487 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00723947 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0072339 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00718969 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00717123 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00716581 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00711881 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0070873 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00706931 |
| KRT23 | keratin 23, type I | -0.00705553 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | -0.00704383 |
| AQP4 | aquaporin 4 | -0.00698255 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00693831 |
| OXTR | oxytocin receptor | -0.00693793 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00692491 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00691812 |
| RET | ret proto-oncogene | -0.00690084 |
| HHLA3 | HERV-H LTR-associating 3 | -0.00674749 |
| TMEM100 | transmembrane protein 100 | -0.00667871 |
| KLHL41 | kelch-like family member 41 | -0.00666791 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00666568 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00666011 |
| GAL | galanin/GMAP prepropeptide | -0.00664916 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00662512 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00662156 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0065982 |
| RAB25 | RAB25, member RAS oncogene family | -0.00659739 |
| TTN | titin | -0.00659109 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00658253 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00656878 |
| S100A12 | S100 calcium binding protein A12 | -0.00654141 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00649666 |
| KIAA0125 | KIAA0125 | -0.00648864 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.00647921 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00645053 |
| PTHLH | parathyroid hormone-like hormone | -0.00644322 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00643994 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00643852 |
| BEX1 | brain expressed, X-linked 1 | -0.00642676 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0064071 |
| S100A14 | S100 calcium binding protein A14 | -0.00640178 |
| PRF1 | perforin 1 (pore forming protein) | -0.0064001 |
| FAM169A | family with sequence similarity 169, member A | -0.00635628 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00634981 |
| LDB2 | LIM domain binding 2 | -0.00631085 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00629693 |
| TMEM176B | transmembrane protein 176B | -0.00625102 |
| RGCC | regulator of cell cycle | -0.00623368 |
| FNBP1 | formin binding protein 1 | -0.00618023 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0061585 |
| MB | myoglobin | -0.00614222 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00613041 |
| CD99 | CD99 molecule | -0.00611297 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00609816 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00609733 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00607012 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -0.00605406 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00605204 |
| FERMT1 | fermitin family member 1 | -0.00603115 |
| ABLIM1 | actin binding LIM protein 1 | -0.00595669 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00591376 |
| RHOH | ras homolog family member H | -0.00588978 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00585579 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00585548 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00584176 |
| HBB | hemoglobin, beta | -0.00583734 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00581919 |
| MYO1C | myosin IC | -0.0058024 |
| AQP9 | aquaporin 9 | -0.00580157 |
| COL1A2 | collagen, type I, alpha 2 | -0.00578364 |
| ZIC1 | Zic family member 1 | -0.00577656 |
| PRKCA | protein kinase C, alpha | -0.00573067 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0057215 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00571659 |
| COBL | cordon-bleu WH2 repeat protein | -0.00570901 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00567667 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.00566668 |
| NKX2-1 | NK2 homeobox 1 | -0.0056579 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00564132 |
| CD81 | CD81 molecule | -0.0056283 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -0.00561314 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00560379 |
| CST7 | cystatin F (leukocystatin) | -0.00558682 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00558607 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00558071 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00557561 |
| DTNA | dystrobrevin, alpha | -0.00557436 |
| CLCA2 | chloride channel accessory 2 | -0.00556925 |
| EDNRB | endothelin receptor type B | -0.00556654 |
| NEFH | neurofilament, heavy polypeptide | -0.00555607 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00555423 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | -0.00554483 |
| MREG | melanoregulin | -0.00554474 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00554471 |
| GNLY | granulysin | -0.00550772 |
| S100A8 | S100 calcium binding protein A8 | -0.00549908 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00548969 |
| IRF6 | interferon regulatory factor 6 | -0.00547754 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00547406 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0054672 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | -0.00544518 |
| PEG3 | paternally expressed 3 | -0.00544001 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00543443 |
| TEAD4 | TEA domain family member 4 | -0.00542026 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00540392 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0053926 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00538988 |
| NDRG2 | NDRG family member 2 | -0.00537961 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00534689 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | -0.00532066 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.005315 |
| NRN1 | neuritin 1 | -0.00528964 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00527536 |
| CA3 | carbonic anhydrase III | -0.00527145 |
| ZNF226 | zinc finger protein 226 | -0.0052549 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00525096 |
| HP | haptoglobin | -0.00524318 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00524204 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00524114 |
| IL1A | interleukin 1, alpha | -0.00523894 |
| AUTS2 | autism susceptibility candidate 2 | -0.00523604 |
| FTO | fat mass and obesity associated | -0.00521531 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -0.00520976 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00520302 |
| PLP1 | proteolipid protein 1 | -0.00520007 |
| S100A4 | S100 calcium binding protein A4 | -0.00519503 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00518197 |
| DSG1 | desmoglein 1 | -0.00516358 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00516079 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.0051574 |
| EGR2 | early growth response 2 | -0.00515663 |
| PEX7 | peroxisomal biogenesis factor 7 | -0.00514519 |
| MMP10 | matrix metallopeptidase 10 | -0.00513732 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00511693 |
| ACYP2 | acylphosphatase 2, muscle type | -0.0051137 |
| RPS26 | ribosomal protein S26 | -0.00509368 |
| CAPN6 | calpain 6 | -0.00508138 |
| CUX2 | cut-like homeobox 2 | -0.00506936 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00506628 |
| TMEM255A | transmembrane protein 255A | -0.00505935 |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | -0.0050515 |
| SEPTIN9 | septin 9 | -0.00503937 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00503661 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00503258 |
| TMEM176A | transmembrane protein 176A | -0.00502182 |
| SMPX | small muscle protein, X-linked | -0.00501814 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -0.00501253 |
| CLC | Charcot-Leyden crystal galectin | -0.00500514 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00500192 |
| NLGN4X | neuroligin 4, X-linked | -0.00499397 |
| IL2RB | interleukin 2 receptor, beta | -0.00498548 |
| IFI44L | interferon-induced protein 44-like | -0.0049741 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | -0.00495696 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00495327 |
| PLIN3 | perilipin 3 | -0.00494851 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00494826 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00494742 |
| CHMP2A | charged multivesicular body protein 2A | -0.00494301 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.00494183 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 | -0.00494106 |
| TARP | TCR gamma alternate reading frame protein | -0.00492874 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00492783 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00492218 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.00492075 |
| DAXX | death-domain associated protein | -0.00491501 |
| TAPBP | TAP binding protein (tapasin) | -0.00489053 |
| USP18 | ubiquitin specific peptidase 18 | -0.00488958 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00488693 |
| GLUL | glutamate-ammonia ligase | -0.00488514 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00488138 |
| ANOS1 | anosmin 1 | -0.00487745 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | -0.0048606 |
| DSG3 | desmoglein 3 | -0.00485979 |
| PTN | pleiotrophin | -0.00485284 |
| PRR5L | proline rich 5 like | -0.00484923 |
| TRAF1 | TNF receptor-associated factor 1 | -0.00482653 |
| SAV1 | salvador family WW domain containing protein 1 | -0.0048088 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00479616 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00477824 |
| PAH | phenylalanine hydroxylase | -0.00477542 |
| PON3 | paraoxonase 3 | -0.00477282 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00476262 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00476139 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | -0.00475935 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | -0.00474689 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00474543 |
| ITM2C | integral membrane protein 2C | -0.00473875 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.00473696 |
| CALML5 | calmodulin-like 5 | -0.00473496 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.004726 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00472523 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00471266 |
| CD52 | CD52 molecule | -0.00471117 |
| SALL1 | spalt-like transcription factor 1 | -0.00470684 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00470485 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00470478 |
