CHUK Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description conserved helix-loop-helix ubiquitous kinase|This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1147)
External Link http://www.ncbi.nlm.nih.gov/gene/1147
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Genes

24 substrates of the kinase CHUK from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
BBC3 BCL2 binding component 3
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ELAVL1 ELAV like RNA binding protein 1
ESR1 estrogen receptor 1
FOXA2 forkhead box A2
FOXO3 forkhead box O3
H3F3B H3 histone, family 3B (H3.3B)
IRS1 insulin receptor substrate 1
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PIAS1 protein inhibitor of activated STAT, 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TRAF4 TNF receptor-associated factor 4