| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | capicua transcriptional repressor|The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID:21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015] (NCBI Entrez Gene Database, 23152) |
| External Link | https://ncbi.nlm.nih.gov/gene/23152 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CIC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0158785 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0156904 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0154835 |
| XIC | X chromosome inactivation center | 0.0150466 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0147593 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0135191 |
| S100A10 | S100 calcium binding protein A10 | 0.0134116 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0132418 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0125465 |
| KRT19 | keratin 19, type I | 0.0124276 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0122171 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0120305 |
| HIST1H2BK | histone cluster 1, H2bk | 0.0120048 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0118545 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0117449 |
| S100P | S100 calcium binding protein P | 0.0113937 |
| MMP7 | matrix metallopeptidase 7 | 0.0109884 |
| TPD52L1 | tumor protein D52-like 1 | 0.0107719 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0102668 |
| PRAME | preferentially expressed antigen in melanoma | 0.0101636 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0100377 |
| GALC | galactosylceramidase | 0.00997472 |
| ANXA1 | annexin A1 | 0.00977653 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00966566 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00958305 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00950087 |
| MYBPC1 | myosin binding protein C, slow type | 0.0094406 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00936755 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00929012 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00928848 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00927718 |
| UPP1 | uridine phosphorylase 1 | 0.00922512 |
| MICB | MHC class I polypeptide-related sequence B | 0.00915233 |
| STC2 | stanniocalcin 2 | 0.00914272 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00908965 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00902825 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00895722 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00893636 |
| ANXA3 | annexin A3 | 0.0088345 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00877775 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00875751 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00871022 |
| IQCG | IQ motif containing G | 0.00865841 |
| JUNB | jun B proto-oncogene | 0.00863047 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00862443 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00861728 |
| H1-2 | H1.2 linker histone, cluster member | 0.00856094 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00854518 |
| KYNU | kynureninase | 0.00851027 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00843343 |
| TPD52 | tumor protein D52 | 0.00842169 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00842133 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00840321 |
| WASHC4 | WASH complex subunit 4 | 0.00834666 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00834618 |
| NUP58 | nucleoporin 58 | 0.00830518 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00830246 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00826243 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00822148 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00821712 |
| KLK6 | kallikrein-related peptidase 6 | 0.00819925 |
| IL32 | interleukin 32 | 0.00813089 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00812308 |
| KRT81 | keratin 81, type II | 0.00811893 |
| CHPT1 | choline phosphotransferase 1 | 0.00805308 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00804104 |
| KLK10 | kallikrein-related peptidase 10 | 0.0080214 |
| MMP11 | matrix metallopeptidase 11 | 0.008002 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00799981 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00799782 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00799694 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00795648 |
| BCL2A1 | BCL2-related protein A1 | 0.00794175 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00793903 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00789486 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00787534 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00784343 |
| LUM | lumican | 0.00783842 |
| KRT7 | keratin 7, type II | 0.00783031 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00780681 |
| PLAU | plasminogen activator, urokinase | 0.00780184 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00780172 |
| LAMC2 | laminin, gamma 2 | 0.00778679 |
| HMOX1 | heme oxygenase 1 | 0.00768632 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00767968 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00766126 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00761821 |
| RRAGD | Ras-related GTP binding D | 0.00760671 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00759795 |
| EREG | epiregulin | 0.00759776 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00759152 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00758624 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00751406 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00747449 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00746282 |
| ITK | IL2-inducible T-cell kinase | 0.00741486 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00740658 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00740357 |
| OAT | ornithine aminotransferase | 0.0073854 |
| DUSP14 | dual specificity phosphatase 14 | 0.00732803 |
| CLDN7 | claudin 7 | 0.0073222 |
| EVI2A | ecotropic viral integration site 2A | 0.00731699 |
| KRT23 | keratin 23, type I | 0.00729702 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00720996 |
| CHN1 | chimerin 1 | 0.00716114 |
| TFF1 | trefoil factor 1 | 0.0071611 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00714739 |
| KRT8 | keratin 8, type II | 0.00710849 |
| ETNK1 | ethanolamine kinase 1 | 0.00710149 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00707794 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00702895 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00702828 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00702675 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00702489 |
| PLPP2 | phospholipid phosphatase 2 | 0.00701013 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00699965 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0069775 |
| GATA6 | GATA binding protein 6 | 0.00694993 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00693883 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00693388 |
| RND1 | Rho family GTPase 1 | 0.00689616 |
| TMEM59 | transmembrane protein 59 | 0.00689407 |
| MSMB | microseminoprotein, beta- | 0.00689074 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00688229 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00687241 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00684153 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00683506 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00683229 |
| IL1B | interleukin 1, beta | 0.00683157 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00683137 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00682288 |
| TSPAN8 | tetraspanin 8 | 0.00680671 |
| KRT15 | keratin 15, type I | 0.00680161 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00677234 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00677082 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00677006 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00676834 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00676599 |
| MX1 | MX dynamin-like GTPase 1 | 0.00676167 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00675069 |
| GPR137B | G protein-coupled receptor 137B | 0.00673822 |
| IFI35 | interferon-induced protein 35 | 0.0067168 |
| USP18 | ubiquitin specific peptidase 18 | 0.00670783 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00670403 |
| KLHL24 | kelch-like family member 24 | 0.00666838 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00665929 |
| GPR65 | G protein-coupled receptor 65 | 0.00664591 |
| GALE | UDP-galactose-4-epimerase | 0.00664142 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00663074 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00662181 |
| IFI44 | interferon-induced protein 44 | 0.00660984 |
| TWF1 | twinfilin actin binding protein 1 | 0.00659121 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0065581 |
| MARCKSL1 | MARCKS-like 1 | 0.00654758 |
| IL6 | interleukin 6 | 0.00653177 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00651434 |
| GLRX | glutaredoxin (thioltransferase) | 0.00649869 |
| SDCBP | syndecan binding protein (syntenin) | 0.00647435 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00646954 |
| IFI44L | interferon-induced protein 44-like | 0.00646133 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00645141 |
| ATF3 | activating transcription factor 3 | 0.00642675 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00642565 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00642137 |
| CHMP5 | charged multivesicular body protein 5 | 0.00640509 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00639703 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00639596 |
| ZNF267 | zinc finger protein 267 | 0.00638895 |
| HEPH | hephaestin | 0.00637384 |
| IL1R2 | interleukin 1 receptor, type II | 0.00637171 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00635072 |
| CCNA1 | cyclin A1 | 0.00635057 |
| GUCY2C | guanylate cyclase 2C | 0.00634381 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00634157 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00633611 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00632428 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0063018 |
| MLPH | melanophilin | 0.00629659 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00629542 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.00628846 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00628431 |
| DUSP5 | dual specificity phosphatase 5 | 0.00626981 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00626911 |
| GLRX2 | glutaredoxin 2 | 0.00625317 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00624219 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00623492 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00623337 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00622612 |
| MMP12 | matrix metallopeptidase 12 | 0.00621864 |
| OLFM4 | olfactomedin 4 | 0.0061911 |
| CYB5R4 | cytochrome b5 reductase 4 | 0.00618991 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00617633 |
| CTH | cystathionine gamma-lyase | 0.00612402 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00611779 |
| CA2 | carbonic anhydrase II | 0.00611201 |
| TARP | TCR gamma alternate reading frame protein | 0.00608714 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00606802 |
| REEP5 | receptor accessory protein 5 | 0.00606751 |
| COCH | cochlin | 0.00606719 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.0060604 |
| RFK | riboflavin kinase | 0.00605827 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00605722 |
| STAT4 | signal transducer and activator of transcription 4 | 0.00604047 |
| ACTN1 | actinin, alpha 1 | 0.00603156 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00601829 |
| LBH | limb bud and heart development | 0.00601637 |
| SNAI2 | snail family zinc finger 2 | 0.00600476 |
| IRS2 | insulin receptor substrate 2 | 0.00600132 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00598361 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00597707 |
| TDRD7 | tudor domain containing 7 | 0.00597536 |
| LY96 | lymphocyte antigen 96 | 0.00597087 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00596036 |
| GOLM1 | golgi membrane protein 1 | 0.00594631 |
| MYO1C | myosin IC | 0.00594423 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00593981 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00593513 |
| ATF4 | activating transcription factor 4 | 0.00590841 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00590635 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00590138 |
| KLK11 | kallikrein-related peptidase 11 | 0.00590111 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00589286 |
| GTF2B | general transcription factor IIB | 0.00588015 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00586693 |
| CLIC4 | chloride intracellular channel 4 | 0.005866 |
| PSEN1 | presenilin 1 | 0.0058635 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00586267 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00583443 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.00583061 |
| IRF1 | interferon regulatory factor 1 | 0.00578901 |
| CD38 | CD38 molecule | 0.00578416 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00577453 |
| CHI3L2 | chitinase 3-like 2 | 0.00577214 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00576601 |
| HK2 | hexokinase 2 | 0.00576227 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00575809 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00574744 |
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.00573199 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00572892 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | 0.00572045 |
| REG1A | regenerating islet-derived 1 alpha | 0.005717 |
| WTAP | Wilms tumor 1 associated protein | 0.00570662 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00569612 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00569056 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00568638 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00568603 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00567794 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00565237 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00565068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0212051 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0187488 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0160687 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.016016 |
| PTK2 | protein tyrosine kinase 2 | -0.0139935 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.013673 |
| RGS5 | regulator of G-protein signaling 5 | -0.0134999 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0134706 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0126552 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0119006 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0115284 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0111947 |
| CLU | clusterin | -0.0110796 |
| METTL7A | methyltransferase like 7A | -0.0109249 |
| SYBU | syntabulin (syntaxin-interacting) | -0.0107195 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0106675 |
| DHFR | dihydrofolate reductase | -0.00998118 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00981171 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00977812 |
| TMSB15A | thymosin beta 15a | -0.00962618 |
| CP | ceruloplasmin (ferroxidase) | -0.00946059 |
| FHL1 | four and a half LIM domains 1 | -0.0094174 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00918499 |
| FKBP5 | FK506 binding protein 5 | -0.00901205 |
| SETBP1 | SET binding protein 1 | -0.00899567 |
| CES1 | carboxylesterase 1 | -0.00895054 |
| HOXB2 | homeobox B2 | -0.00894397 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00894302 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00887995 |
| MAOA | monoamine oxidase A | -0.00886604 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00877493 |
| PLN | phospholamban | -0.00869261 |
| CBS | cystathionine-beta-synthase | -0.00862317 |
| CPE | carboxypeptidase E | -0.00859534 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00858264 |
| MGP | matrix Gla protein | -0.00854913 |
| OLFM1 | olfactomedin 1 | -0.00853078 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00852978 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00844401 |
| BEX1 | brain expressed, X-linked 1 | -0.00841809 |
| FASN | fatty acid synthase | -0.00838831 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.008358 |
| C7 | complement component 7 | -0.00834178 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00833403 |
| ADAMTSL3 | ADAMTS-like 3 | -0.00832551 |
| SFTPA2 | surfactant protein A2 | -0.00824299 |
| PER3 | period circadian clock 3 | -0.00819959 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00815134 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00803261 |
| GPC3 | glypican 3 | -0.00800478 |
| NID1 | nidogen 1 | -0.00799587 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.00797739 |
| RBPMS | RNA binding protein with multiple splicing | -0.00795843 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | -0.0079359 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00792486 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00792187 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00784969 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00784876 |
| EXPH5 | exophilin 5 | -0.0078202 |
| RAPSN | receptor-associated protein of the synapse | -0.00781003 |
| WDR7 | WD repeat domain 7 | -0.00780147 |
| HMGB1 | high mobility group box 1 | -0.00776654 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00775994 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00768853 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00767276 |
| SFTPC | surfactant protein C | -0.00766073 |
| HIP1 | huntingtin interacting protein 1 | -0.00763725 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00758292 |
| RCAN2 | regulator of calcineurin 2 | -0.00757607 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00753892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00751216 |
| RTN1 | reticulon 1 | -0.00749987 |
| NRN1 | neuritin 1 | -0.00743059 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00736811 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00732778 |
| NPTX2 | neuronal pentraxin II | -0.00729204 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00728964 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0072753 |
| AUTS2 | autism susceptibility candidate 2 | -0.00727502 |
| PER1 | period circadian clock 1 | -0.00722832 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00720068 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00716351 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00714239 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00711383 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0070646 |
| RETREG1 | reticulophagy regulator 1 | -0.00704758 |
| PRR11 | proline rich 11 | -0.00704616 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00704092 |
| HOPX | HOP homeobox | -0.00702591 |
| INSM1 | insulinoma-associated 1 | -0.00702591 |
| HELLS | helicase, lymphoid-specific | -0.00701054 |
| CSNK1E | casein kinase 1, epsilon | -0.0069635 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00696238 |
| CBX5 | chromobox homolog 5 | -0.00694672 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00692863 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00691065 |
| LRRC17 | leucine rich repeat containing 17 | -0.00690523 |
| SALL2 | spalt-like transcription factor 2 | -0.00687867 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.0068577 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00685099 |
| NREP | neuronal regeneration related protein | -0.00680821 |
| RRM1 | ribonucleotide reductase M1 | -0.00678513 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00677479 |
| CDC20 | cell division cycle 20 | -0.00677273 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00677021 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | -0.00674314 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00672417 |
| KIF20A | kinesin family member 20A | -0.00672149 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.00670234 |
| CA9 | carbonic anhydrase IX | -0.00663147 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.0066266 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00659412 |
| CD302 | CD302 molecule | -0.00656546 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00655492 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00655492 |
| MEN1 | multiple endocrine neoplasia I | -0.00654866 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00653138 |
| NEFM | neurofilament, medium polypeptide | -0.00652981 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00651863 |
| TRMT5 | tRNA methyltransferase 5 | -0.00649974 |
| EHD2 | EH-domain containing 2 | -0.00648841 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00645347 |
| FAM107A | family with sequence similarity 107, member A | -0.00645299 |
| CFH | complement factor H | -0.00644485 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00642666 |
| THBS4 | thrombospondin 4 | -0.00642311 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00640509 |
| PDZD2 | PDZ domain containing 2 | -0.00637146 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00636309 |
| FBN2 | fibrillin 2 | -0.00632522 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00632153 |
| DCLK1 | doublecortin-like kinase 1 | -0.00629676 |
| GNAS | GNAS complex locus | -0.00628783 |
| HMGB2 | high mobility group box 2 | -0.00628149 |
| DIXDC1 | DIX domain containing 1 | -0.00627652 |
| TADA2A | transcriptional adaptor 2A | -0.00627631 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00627412 |
| ACSM5 | acyl-CoA synthetase medium-chain family member 5 | -0.00626926 |
| ANOS1 | anosmin 1 | -0.00625931 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00625121 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00623894 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00622452 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00620953 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00620738 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00619226 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00617134 |
| EML1 | echinoderm microtubule associated protein like 1 | -0.00616311 |
| NEBL | nebulette | -0.0061597 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -0.00615194 |
| RET | ret proto-oncogene | -0.00615019 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00614516 |
| SFTPD | surfactant protein D | -0.00614272 |
| INSR | insulin receptor | -0.00612302 |
| PER2 | period circadian clock 2 | -0.00611663 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00610952 |
| H2AFV | H2A histone family, member V | -0.00610446 |
| BRCA1 | breast cancer 1, early onset | -0.00610071 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00609586 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.00609582 |
| COL1A2 | collagen, type I, alpha 2 | -0.00608649 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00608127 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00606227 |
| B3GNT1 | -0.00605263 | |
| MPZL2 | myelin protein zero-like 2 | -0.00602629 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00598417 |
| A2M | alpha-2-macroglobulin | -0.00596545 |
| KRT1 | keratin 1, type II | -0.00596473 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00596214 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00595939 |
| STON1 | stonin 1 | -0.0059015 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00590003 |
| DACH1 | dachshund family transcription factor 1 | -0.00589551 |
| MATN2 | matrilin 2 | -0.00584412 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00584088 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00582104 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00582014 |
| FRY | furry homolog (Drosophila) | -0.00581305 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00580541 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.00580134 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.00580126 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00576448 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00576416 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00576234 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00575774 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00575637 |
| LOXL1 | lysyl oxidase-like 1 | -0.00575541 |
| JAM3 | junctional adhesion molecule 3 | -0.00574781 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00574729 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00574133 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00573615 |
| KLF9 | Kruppel-like factor 9 | -0.00572632 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00572284 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00571533 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00570803 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00570205 |
| NVL | nuclear VCP-like | -0.00568503 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00568388 |
| TMEM176B | transmembrane protein 176B | -0.00567967 |
| SFTPB | surfactant protein B | -0.00567908 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00567829 |
| FADS1 | fatty acid desaturase 1 | -0.00567476 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00566989 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00565277 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00564462 |
| SIRT3 | sirtuin 3 | -0.00563863 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00563324 |
| FAM149A | family with sequence similarity 149, member A | -0.00561482 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.005602 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) | -0.00559714 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0055938 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0055818 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00557714 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00555475 |
| FZD4 | frizzled class receptor 4 | -0.0055533 |
| BGN | biglycan | -0.00551179 |
| CD93 | CD93 molecule | -0.00550076 |
| PDGFD | platelet derived growth factor D | -0.00549022 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00548236 |
| CTBP1 | C-terminal binding protein 1 | -0.00545868 |
| NFASC | neurofascin | -0.005458 |
| HYOU1 | hypoxia up-regulated 1 | -0.00544779 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00544686 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00544649 |
| KRT2 | keratin 2, type II | -0.00543935 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00543732 |
| F2R | coagulation factor II (thrombin) receptor | -0.00543096 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00542226 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00541366 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00541075 |
| FGL2 | fibrinogen-like 2 | -0.00540393 |
| PIMREG | PICALM interacting mitotic regulator | -0.00537861 |
| FGG | fibrinogen gamma chain | -0.00537313 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00536422 |
| NBEA | neurobeachin | -0.00535894 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00535809 |
| ZNF160 | zinc finger protein 160 | -0.00535114 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00535111 |
| ASPH | aspartate beta-hydroxylase | -0.00533615 |
| GAA | glucosidase, alpha; acid | -0.00533173 |
| CRMP1 | collapsin response mediator protein 1 | -0.00532185 |
| GPX3 | glutathione peroxidase 3 | -0.00530822 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00530753 |
| ELN | elastin | -0.00530396 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00529213 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00529137 |
| FABP7 | fatty acid binding protein 7, brain | -0.00527765 |
| SCG5 | secretogranin V | -0.00527344 |
| NYNRIN | NYN domain and retroviral integrase containing | -0.00527178 |
| ZNF721 | zinc finger protein 721 | -0.00527016 |
| JUND | jun D proto-oncogene | -0.00526402 |
