CINALUKAST Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma. (Chemical Entities of Biological Interest Ontology, CHEBI_126598)
External Link https://dgidb.org/results?searchType=drug&searchTerms=CINALUKAST
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Genes

3 interacting proteins for the CINALUKAST drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CYSLTR1 cysteinyl leukotriene receptor 1 2.03585
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.0425157
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.0199142