CIT Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description citron rho-interacting serine/threonine kinase|This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 11113)
External Link https://ncbi.nlm.nih.gov/gene/11113
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Genes

500 genes differentially expressed following the CIT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0180964
STK10 serine/threonine kinase 10 0.0131732
KRT5 keratin 5, type II 0.0129908
LAPTM4B lysosomal protein transmembrane 4 beta 0.0114275
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.0104687
CXADR coxsackie virus and adenovirus receptor 0.0103785
COL4A6 collagen, type IV, alpha 6 0.0103584
OXA1L oxidase (cytochrome c) assembly 1-like 0.00989587
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00975744
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00972903
S100A7 S100 calcium binding protein A7 0.0096554
LTA4H leukotriene A4 hydrolase 0.00930415
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00918754
TYRP1 tyrosinase-related protein 1 0.00916046
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.0090921
NELL2 NEL-like 2 (chicken) 0.00906936
F2R coagulation factor II (thrombin) receptor 0.00902708
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00902327
COCH cochlin 0.00879189
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00876033
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00874847
DIPK1A divergent protein kinase domain 1A 0.00869323
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00839125
NTS neurotensin 0.00837226
PRPF4 pre-mRNA processing factor 4 0.00827869
WFDC1 WAP four-disulfide core domain 1 0.00826008
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00820683
PLXNC1 plexin C1 0.00816002
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00813224
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00809567
DMBT1 deleted in malignant brain tumors 1 0.00807999
CCDC85B coiled-coil domain containing 85B 0.00803151
SEPTIN9 septin 9 0.00800627
GSDME gasdermin E 0.00796998
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0078548
GSTP1 glutathione S-transferase pi 1 0.00776408
MEIS1 Meis homeobox 1 0.00772763
NVL nuclear VCP-like 0.00766018
TOMM34 translocase of outer mitochondrial membrane 34 0.00759485
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00759248
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00755193
LARS1 leucyl-tRNA synthetase 1 0.00754202
INAVA innate immunity activator 0.00753806
PBX1 pre-B-cell leukemia homeobox 1 0.00751129
S100A2 S100 calcium binding protein A2 0.00748167
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00747771
TBX2 T-box 2 0.00744651
PDLIM1 PDZ and LIM domain 1 0.00742936
SRPX sushi-repeat containing protein, X-linked 0.0074198
CLEC11A C-type lectin domain family 11, member A 0.00738722
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00733873
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00726777
KRT17 keratin 17, type I 0.0071788
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00709198
MXRA7 matrix-remodelling associated 7 0.00704888
KDM5D lysine (K)-specific demethylase 5D 0.00701824
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0070169
BCHE butyrylcholinesterase 0.00698606
C3ORF14 chromosome 3 open reading frame 14 0.00695628
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00691016
GMDS GDP-mannose 4,6-dehydratase 0.0068564
SFTPD surfactant protein D 0.00684998
NAP1L1 nucleosome assembly protein 1-like 1 0.00684258
NPR3 natriuretic peptide receptor 3 0.00683799
ADGRG2 adhesion G protein-coupled receptor G2 0.00678702
TMEM204 transmembrane protein 204 0.00675326
SPRY4 sprouty homolog 4 (Drosophila) 0.00673523
TMC5 transmembrane channel-like 5 0.00673027
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene 0.00672914
TUBA1A tubulin, alpha 1a 0.00664399
MUC16 mucin 16, cell surface associated 0.00664255
IFITM2 interferon induced transmembrane protein 2 0.00663016
MACF1 microtubule-actin crosslinking factor 1 0.00658376
KRT14 keratin 14, type I 0.00653123
SLC44A4 solute carrier family 44, member 4 0.0065171
MYH11 myosin, heavy chain 11, smooth muscle 0.00651637
NUP85 nucleoporin 85kDa 0.0065024
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00645016
MID1 midline 1 0.00643218
MOXD1 monooxygenase, DBH-like 1 0.0064265
COG7 component of oligomeric golgi complex 7 0.00642102
SLPI secretory leukocyte peptidase inhibitor 0.00641387
KRT6A keratin 6A, type II 0.00636036
PRSS21 protease, serine, 21 (testisin) 0.00626342
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00623751
MEIS2 Meis homeobox 2 0.00623112
RUNX3 runt-related transcription factor 3 0.00623029
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00621757
LAMP5 lysosomal-associated membrane protein family, member 5 0.00620943
FBLN5 fibulin 5 0.0061827
SFTPC surfactant protein C 0.00617085
ALCAM activated leukocyte cell adhesion molecule 0.00615422
AEBP1 AE binding protein 1 0.00614015
SMYD3 SET and MYND domain containing 3 0.00613343
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.00612009
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00611318
ZW10 zw10 kinetochore protein 0.00611053
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00609184
MFSD10 major facilitator superfamily domain containing 10 0.00608156
FERMT1 fermitin family member 1 0.00606634
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00605988
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00603505
CIRBP cold inducible RNA binding protein 0.00602351
SLIT1 slit homolog 1 (Drosophila) 0.00601077
MSLN mesothelin 0.00601069
SFRP1 secreted frizzled-related protein 1 0.00600467
NSG1 neuron specific gene family member 1 0.00598968
RRBP1 ribosome binding protein 1 0.0059895
KYNU kynureninase 0.00598538
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00598352
PWP1 PWP1 homolog (S. cerevisiae) 0.00598159
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00596251
PODXL podocalyxin-like 0.00594289
MME membrane metallo-endopeptidase 0.00591919
MED22 mediator complex subunit 22 0.00590384
TKTL1 transketolase-like 1 0.00589612
SSRP1 structure specific recognition protein 1 0.00589463
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00587738
PRPF6 pre-mRNA processing factor 6 0.00587182
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00585396
LGALS1 lectin, galactoside-binding, soluble, 1 0.00583581
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00582731
C7 complement component 7 0.0058233
USP11 ubiquitin specific peptidase 11 0.00581802
SFTPA2 surfactant protein A2 0.00581551
ADD3 adducin 3 (gamma) 0.00581217
HAUS2 HAUS augmin-like complex, subunit 2 0.00580038
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.00579752
ENO1 enolase 1, (alpha) 0.0057112
CA9 carbonic anhydrase IX 0.00568812
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.00567652
FKBP9 FK506 binding protein 9, 63 kDa 0.0056414
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00563899
CES1 carboxylesterase 1 0.00563256
TSPAN4 tetraspanin 4 0.00563116
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00561017
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00559408
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00559176
MAGED1 melanoma antigen family D1 0.00558155
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00558039
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00557511
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00557287
GAS1 growth arrest-specific 1 0.00556618
THBS2 thrombospondin 2 0.00554489
RIPK4 receptor-interacting serine-threonine kinase 4 0.0055396
CAPN3 calpain 3, (p94) 0.00552031
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00550885
SORBS3 sorbin and SH3 domain containing 3 0.00548044
ZNF160 zinc finger protein 160 0.00545824
SRPRA SRP receptor subunit alpha 0.00544797
BTG3 BTG family, member 3 0.00544686
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00543727
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.00543239
COL10A1 collagen, type X, alpha 1 0.00543189
GTPBP8 GTP-binding protein 8 (putative) 0.00543166
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00539935
NXN nucleoredoxin 0.00539311
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.00538752
MAST4 microtubule associated serine/threonine kinase family member 4 0.00537096
BPIFA1 BPI fold containing family A, member 1 0.00536735
RNF144A ring finger protein 144A 0.0053603
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00535025
MMP1 matrix metallopeptidase 1 0.00532615
DACH1 dachshund family transcription factor 1 0.00532491
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.00532096
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00531622
ZGPAT zinc finger, CCCH-type with G patch domain 0.00530981
LAMB1 laminin, beta 1 0.00529258
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00526768
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.00526349
PI3 peptidase inhibitor 3, skin-derived 0.0052584
LIG1 ligase I, DNA, ATP-dependent 0.00519481
CPNE1 copine I 0.00519319
GPR143 G protein-coupled receptor 143 0.00518247
TP53I3 tumor protein p53 inducible protein 3 0.00517619
PNMA8A PNMA family member 8A 0.00516016
COL9A2 collagen, type IX, alpha 2 0.00515869
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00515543
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00514901
TMSB15A thymosin beta 15a 0.00514897
RCAN1 regulator of calcineurin 1 0.00512986
ASB9 ankyrin repeat and SOCS box containing 9 0.00512259
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00512198
SPRED2 sprouty-related, EVH1 domain containing 2 0.00511775
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.0051122
PDZK1IP1 PDZK1 interacting protein 1 0.00510044
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.0050991
PLS3 plastin 3 0.00508927
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.00507902
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.00505682
CD48 CD48 molecule 0.00505516
MSMB microseminoprotein, beta- 0.00505127
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00502761
FXYD5 FXYD domain containing ion transport regulator 5 0.00501046
GPX2 glutathione peroxidase 2 0.00501038
FUS FUS RNA binding protein 0.00500597
PRKCA protein kinase C, alpha 0.00500246
ADCY3 adenylate cyclase 3 0.00500115
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00499884
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.00499535
ADGRG6 adhesion G protein-coupled receptor G6 0.00499185
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00499094
MAGT1 magnesium transporter 1 0.00498461
INSM1 insulinoma-associated 1 0.00498271
DAPK1 death-associated protein kinase 1 0.00496814
AGR2 anterior gradient 2 0.00495838
COL4A5 collagen, type IV, alpha 5 0.00495225
THY1 Thy-1 cell surface antigen 0.00494278
OCA2 oculocutaneous albinism II 0.00493825
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00493726
PTDSS1 phosphatidylserine synthase 1 0.00493332
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00492794
PLAT plasminogen activator, tissue 0.00492385
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0049201
ITM2A integral membrane protein 2A 0.00488347
CAST calpastatin 0.00484837
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00484531
PTCH1 patched 1 0.00483934
GGCT gamma-glutamylcyclotransferase 0.00482765
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.00481919
ACOX2 acyl-CoA oxidase 2, branched chain 0.00481659
PTTG1 pituitary tumor-transforming 1 0.00481116
ACE2 angiotensin I converting enzyme 2 0.00480879
RPN2 ribophorin II 0.00480565
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00478358
ANXA6 annexin A6 0.00478004
SCGB2A1 secretoglobin, family 2A, member 1 0.00477904
KLK5 kallikrein-related peptidase 5 0.0047681
ASF1B anti-silencing function 1B histone chaperone 0.0047632
CCN2 cellular communication network factor 2 0.00475901
NELFCD negative elongation factor complex member C/D 0.00475674
VCL vinculin 0.00474382
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00473779
PRKCQ protein kinase C, theta 0.00473396
PMEL premelanosome protein 0.00473157
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00472808
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00472687
NDNF neuron-derived neurotrophic factor 0.0047213
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.00471168
DENND2B DENN domain containing 2B 0.00470653
QDPR quinoid dihydropteridine reductase 0.00470475
RHOC ras homolog family member C 0.00470099
ASCL1 achaete-scute family bHLH transcription factor 1 0.00469634
SLC2A4RG SLC2A4 regulator 0.00469236
SHCBP1 SHC SH2-domain binding protein 1 0.00468306
MXRA5 matrix-remodelling associated 5 0.00467793
FAM171A1 family with sequence similarity 171, member A1 0.00467148
CCL5 chemokine (C-C motif) ligand 5 0.00467001
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00466689
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00466128

decreased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II -0.0190388
F13A1 coagulation factor XIII, A1 polypeptide -0.0128339
CLU clusterin -0.0125237
TPD52L1 tumor protein D52-like 1 -0.0116493
FABP4 fatty acid binding protein 4, adipocyte -0.0116205
ACKR3 atypical chemokine receptor 3 -0.0114793
CRYAB crystallin, alpha B -0.0114355
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0112073
RTN2 reticulon 2 -0.0111151
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0107032
TMEM176B transmembrane protein 176B -0.0107024
HSPB8 heat shock 22kDa protein 8 -0.0104186
CD36 CD36 molecule (thrombospondin receptor) -0.0103903
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.010186
SLC38A1 solute carrier family 38, member 1 -0.010136
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00996216
TXNDC9 thioredoxin domain containing 9 -0.00992921
ABHD3 abhydrolase domain containing 3 -0.00980866
HIST1H2AC histone cluster 1, H2ac -0.00980324
CD9 CD9 molecule -0.00971014
EIF5A eukaryotic translation initiation factor 5A -0.00955601
ALOX5 arachidonate 5-lipoxygenase -0.00951999
IGFBP5 insulin-like growth factor binding protein 5 -0.00951137
MYBPC1 myosin binding protein C, slow type -0.00936406
LEPR leptin receptor -0.00931439
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00914562
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00910785
F3 coagulation factor III (thromboplastin, tissue factor) -0.00909673
G0S2 G0/G1 switch 2 -0.00908711
STK39 serine threonine kinase 39 -0.00904867
HHEX hematopoietically expressed homeobox -0.00899204
CPE carboxypeptidase E -0.00888289
FUCA1 fucosidase, alpha-L- 1, tissue -0.00885815
CCNG2 cyclin G2 -0.00881912
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00880937
LYZ lysozyme -0.00880799
XIC X chromosome inactivation center -0.00877965
GRB14 growth factor receptor-bound protein 14 -0.008711
PLBD1 phospholipase B domain containing 1 -0.00859082
WTAP Wilms tumor 1 associated protein -0.00858255
SEPP1 selenoprotein P, plasma, 1 -0.00856345
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0084908
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00843981
HAT1 histone acetyltransferase 1 -0.00839
MNDA myeloid cell nuclear differentiation antigen -0.00829827
FADS3 fatty acid desaturase 3 -0.00828438
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00827986
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00826222
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00821578
SDC2 syndecan 2 -0.00819153
TGIF1 TGFB-induced factor homeobox 1 -0.0081763
IL6 interleukin 6 -0.00809961
FOXO1 forkhead box O1 -0.00807481
S100P S100 calcium binding protein P -0.0080493
PPARG peroxisome proliferator-activated receptor gamma -0.00804912
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00803947
EVI2A ecotropic viral integration site 2A -0.00803143
HNMT histamine N-methyltransferase -0.00801821
DEFA4 defensin, alpha 4, corticostatin -0.00801684
SCRG1 stimulator of chondrogenesis 1 -0.00799103
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00792206
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00791176
GLUL glutamate-ammonia ligase -0.00788919
ZBTB18 zinc finger and BTB domain containing 18 -0.00788732
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00787773
SATB2 SATB homeobox 2 -0.00782968
CTSZ cathepsin Z -0.00782276
MT1M metallothionein 1M -0.00781386
DOCK9 dedicator of cytokinesis 9 -0.00772085
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00771273
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00770965
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00768209
H1-0 H1.0 linker histone -0.00764435
FZD5 frizzled class receptor 5 -0.0076278
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00759513
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00748093
MOB4 MOB family member 4, phocein -0.00747648
ZHX2 zinc fingers and homeoboxes 2 -0.00745609
ZFPM2 zinc finger protein, FOG family member 2 -0.00745468
MAPK6 mitogen-activated protein kinase 6 -0.0074168
PLIN1 perilipin 1 -0.00739432
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00728878
TMEM70 transmembrane protein 70 -0.00728056
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00726894
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00726824
CDO1 cysteine dioxygenase type 1 -0.00723847
TRPS1 trichorhinophalangeal syndrome I -0.00721953
MRPL13 mitochondrial ribosomal protein L13 -0.00720397
S100A12 S100 calcium binding protein A12 -0.00719468
NT5E 5'-nucleotidase, ecto (CD73) -0.00718647
FGF13 fibroblast growth factor 13 -0.00718115
TNNT1 troponin T type 1 (skeletal, slow) -0.00715497
PDCD10 programmed cell death 10 -0.00715092
TSPO translocator protein (18kDa) -0.00714577
NMD3 NMD3 ribosome export adaptor -0.00714215
IL6ST interleukin 6 signal transducer -0.00714198
TSC22D1 TSC22 domain family, member 1 -0.00702328
MIR22HG MIR22 host gene -0.00702151
ARMT1 acidic residue methyltransferase 1 -0.00701533
GPX3 glutathione peroxidase 3 -0.00698077
STC2 stanniocalcin 2 -0.00696523
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0069461
TRIB3 tribbles pseudokinase 3 -0.0069379
FZD6 frizzled class receptor 6 -0.0069259
UNC50 unc-50 homolog (C. elegans) -0.00690809
TPBG trophoblast glycoprotein -0.00690685
EMP1 epithelial membrane protein 1 -0.00687426
DUSP5 dual specificity phosphatase 5 -0.00685002
CAV2 caveolin 2 -0.00675186
CPD carboxypeptidase D -0.00674808
SC5D sterol-C5-desaturase -0.0067415
PLIN2 perilipin 2 -0.00673975
ANKRD10 ankyrin repeat domain 10 -0.00673446
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0067255
SLN sarcolipin -0.00672359
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0066924
DCK deoxycytidine kinase -0.00662925
TMEM126B transmembrane protein 126B -0.00661991
EGR3 early growth response 3 -0.00661617
TMEM176A transmembrane protein 176A -0.0065981
MAOA monoamine oxidase A -0.00658617
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.0065639
RAD23B RAD23 homolog B (S. cerevisiae) -0.00652445
C1QA complement component 1, q subcomponent, A chain -0.00648157
NUP58 nucleoporin 58 -0.0064792
WASHC4 WASH complex subunit 4 -0.006479
SPARCL1 SPARC-like 1 (hevin) -0.00642941
ACTC1 actin, alpha, cardiac muscle 1 -0.00642677
VAMP8 vesicle-associated membrane protein 8 -0.0064188
MEST mesoderm specific transcript -0.00641673
CD163 CD163 molecule -0.00637583
IRS2 insulin receptor substrate 2 -0.0063677
SCARB2 scavenger receptor class B, member 2 -0.00632776
DLD dihydrolipoamide dehydrogenase -0.00631754
WSB1 WD repeat and SOCS box containing 1 -0.00631191
MRPS28 mitochondrial ribosomal protein S28 -0.00629845
CLIC2 chloride intracellular channel 2 -0.00629209
MICU2 mitochondrial calcium uptake 2 -0.00626326
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00625713
ATAD2 ATPase family, AAA domain containing 2 -0.00624233
RNF6 ring finger protein (C3H2C3 type) 6 -0.00621056
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00617848
ISG15 ISG15 ubiquitin-like modifier -0.00614016
DSE dermatan sulfate epimerase -0.00613291
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.00612695
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00612534
NDFIP1 Nedd4 family interacting protein 1 -0.00610348
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00607532
ABAT 4-aminobutyrate aminotransferase -0.00605356
RIDA reactive intermediate imine deaminase A homolog -0.00605259
RND3 Rho family GTPase 3 -0.00605008
COX5B cytochrome c oxidase subunit Vb -0.00604135
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00603729
ADRA2A adrenoceptor alpha 2A -0.00603592
DEPTOR DEP domain containing MTOR-interacting protein -0.0060169
HSPE1 heat shock 10kDa protein 1 -0.00600893
LTF lactotransferrin -0.00600312
CDA cytidine deaminase -0.00599317
ATF3 activating transcription factor 3 -0.00599074
CFD complement factor D (adipsin) -0.00597406
SRPK2 SRSF protein kinase 2 -0.00596645
CCL4 chemokine (C-C motif) ligand 4 -0.00596484
TOR1A torsin family 1, member A (torsin A) -0.00596258
IFI30 interferon, gamma-inducible protein 30 -0.00595063
MARCHF7 membrane associated ring-CH-type finger 7 -0.00593676
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -0.00591721
ZNF423 zinc finger protein 423 -0.00591605
LYST lysosomal trafficking regulator -0.00590275
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -0.00588088
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00587761
H1-2 H1.2 linker histone, cluster member -0.0058517
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00585006
TYROBP TYRO protein tyrosine kinase binding protein -0.00584938
DHDDS dehydrodolichyl diphosphate synthase -0.00584347
MGLL monoglyceride lipase -0.00582479
RHOB ras homolog family member B -0.00582065
PLPP3 phospholipid phosphatase 3 -0.00581325
S100A4 S100 calcium binding protein A4 -0.00579251
LY96 lymphocyte antigen 96 -0.00578903
SELENOT selenoprotein T -0.00577919
CHI3L2 chitinase 3-like 2 -0.00577448
PHACTR2 phosphatase and actin regulator 2 -0.00577278
MET MET proto-oncogene, receptor tyrosine kinase -0.00575606
ATG5 autophagy related 5 -0.00575316
ADGRL4 adhesion G protein-coupled receptor L4 -0.00573217
MEOX2 mesenchyme homeobox 2 -0.00571991
CLCA4 chloride channel accessory 4 -0.00571138
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00570863
ZNF281 zinc finger protein 281 -0.0056999
PEG3 paternally expressed 3 -0.0056963
EIF5B eukaryotic translation initiation factor 5B -0.00566478
TPD52 tumor protein D52 -0.00565778
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0056569
HIST1H2BK histone cluster 1, H2bk -0.00565637
ZMYM2 zinc finger, MYM-type 2 -0.0056213
RAB2A RAB2A, member RAS oncogene family -0.00561927
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00560237
CGRRF1 cell growth regulator with ring finger domain 1 -0.00557934
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00557645
NIBAN1 niban apoptosis regulator 1 -0.00556857
HBP1 HMG-box transcription factor 1 -0.00556633
CYBB cytochrome b-245, beta polypeptide -0.00556195
SCP2 sterol carrier protein 2 -0.00554954
CCN3 cellular communication network factor 3 -0.00554804
ORM1 orosomucoid 1 -0.00553638
COL14A1 collagen, type XIV, alpha 1 -0.00553593
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00552379
IRS1 insulin receptor substrate 1 -0.00551966
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00550976
ELANE elastase, neutrophil expressed -0.00550039
HSPA1A heat shock 70kDa protein 1A -0.00550011
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.00549497
IFI6 interferon, alpha-inducible protein 6 -0.00548463
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00547041
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -0.00545452
IFRD1 interferon-related developmental regulator 1 -0.00545179
CD14 CD14 molecule -0.00544937
OSBPL11 oxysterol binding protein-like 11 -0.00544914
WBP1L WW domain binding protein 1-like -0.00543944
MAIP1 matrix AAA peptidase interacting protein 1 -0.00543216
MSH2 mutS homolog 2 -0.00542706
MRFAP1L1 Morf4 family associated protein 1-like 1 -0.00541629
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00540945
NAV3 neuron navigator 3 -0.00539155
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00535662
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00535093
BMP2 bone morphogenetic protein 2 -0.00534899
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -0.00534792
GJA1 gap junction protein, alpha 1, 43kDa -0.00534655
LMBRD1 LMBR1 domain containing 1 -0.00534365
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0053394
AMOTL2 angiomotin like 2 -0.00532802
RESF1 retroelement silencing factor 1 -0.00532334
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -0.00532076
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -0.00530285
GTF3A general transcription factor IIIA -0.00530187
NRCAM neuronal cell adhesion molecule -0.00529231
CCL8 chemokine (C-C motif) ligand 8 -0.00528032
CCNC cyclin C -0.00526263
ARID5B AT rich interactive domain 5B (MRF1-like) -0.00525096
DMXL2 Dmx-like 2 -0.00524325
HMOX1 heme oxygenase 1 -0.00523376
CD53 CD53 molecule -0.00522592
LEP leptin -0.00519751
MDFIC MyoD family inhibitor domain containing -0.00519723
ZC3H15 zinc finger CCCH-type containing 15 -0.00519693
TRAM1 translocation associated membrane protein 1 -0.0051934
CANX calnexin -0.0051933
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00519216
FGFR2 fibroblast growth factor receptor 2 -0.00518266