CLC Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
External Link https://ncbi.nlm.nih.gov/gene/1178
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Genes

497 genes differentially expressed following the CLC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 0.0134014
RB1 retinoblastoma 1 0.013286
CD36 CD36 molecule (thrombospondin receptor) 0.0132183
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0131607
TYRP1 tyrosinase-related protein 1 0.0123397
ARG1 arginase 1 0.012119
S100A7 S100 calcium binding protein A7 0.0119551
PRR7 proline rich 7 (synaptic) 0.011583
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0114203
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0110906
BCL2A1 BCL2-related protein A1 0.0109354
IFI27 interferon, alpha-inducible protein 27 0.0108977
HLA-DRA major histocompatibility complex, class II, DR alpha 0.0108361
GREM1 gremlin 1, DAN family BMP antagonist 0.0107976
NID1 nidogen 1 0.0107706
CALML5 calmodulin-like 5 0.01061
EGR3 early growth response 3 0.0104416
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0102621
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0102498
GREB1 growth regulation by estrogen in breast cancer 1 0.0102265
GCH1 GTP cyclohydrolase 1 0.010204
TSPAN8 tetraspanin 8 0.0101325
MAP7 microtubule-associated protein 7 0.00999026
COL15A1 collagen, type XV, alpha 1 0.00997896
KYNU kynureninase 0.00997556
NPTX2 neuronal pentraxin II 0.00989413
SGK1 serum/glucocorticoid regulated kinase 1 0.00979067
PDZRN3 PDZ domain containing ring finger 3 0.0097902
SPARCL1 SPARC-like 1 (hevin) 0.00968995
HP haptoglobin 0.00962023
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00959338
DAXX death-domain associated protein 0.0095469
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00954259
CLEC2B C-type lectin domain family 2, member B 0.0094612
ADGRG6 adhesion G protein-coupled receptor G6 0.00944428
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00943983
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00942805
ALCAM activated leukocyte cell adhesion molecule 0.00929852
LEF1 lymphoid enhancer-binding factor 1 0.0091252
F12 coagulation factor XII (Hageman factor) 0.00911462
PI3 peptidase inhibitor 3, skin-derived 0.00905004
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00897778
DCN decorin 0.00885946
CD93 CD93 molecule 0.00883983
SERINC5 serine incorporator 5 0.0088311
TDO2 tryptophan 2,3-dioxygenase 0.00880046
GPX2 glutathione peroxidase 2 0.00872168
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00865388
CHP1 calcineurin-like EF-hand protein 1 0.00861196
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00855261
TOX3 TOX high mobility group box family member 3 0.00854592
FABP1 fatty acid binding protein 1, liver 0.00842674
ALDOB aldolase B, fructose-bisphosphate 0.00838357
VNN1 vanin 1 0.00835268
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00833762
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00833348
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00829693
IRS1 insulin receptor substrate 1 0.00818212
SORD sorbitol dehydrogenase 0.00812831
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00812463
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00805749
IVNS1ABP influenza virus NS1A binding protein 0.00805122
HEPH hephaestin 0.00803558
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.00797125
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.00794718
COL3A1 collagen, type III, alpha 1 0.00784625
CADM1 cell adhesion molecule 1 0.00783754
TBX2 T-box 2 0.0078038
CXCL8 chemokine (C-X-C motif) ligand 8 0.00778863
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00777987
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00776903
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00774692
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0077456
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00774273
KIAA0100 KIAA0100 0.00772805
COL18A1 collagen, type XVIII, alpha 1 0.00762728
KLK11 kallikrein-related peptidase 11 0.00759207
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00755792
PLXNC1 plexin C1 0.0075443
SST somatostatin 0.00752342
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.00752026
S100A12 S100 calcium binding protein A12 0.0075083
FGF13 fibroblast growth factor 13 0.00750597
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00750178
ISG15 ISG15 ubiquitin-like modifier 0.0074133
LY75 lymphocyte antigen 75 0.0074121
KLK10 kallikrein-related peptidase 10 0.0074079
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00739274
NEBL nebulette 0.00737425
CD14 CD14 molecule 0.00733293
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00730999
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00726404
CALML3 calmodulin-like 3 0.0072585
S100A10 S100 calcium binding protein A10 0.00722871
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00720123
ZEB1 zinc finger E-box binding homeobox 1 0.00719305
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00715564
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00711376
ISG20 interferon stimulated exonuclease gene 20kDa 0.00710791
DSG1 desmoglein 1 0.00710689
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00709659
PLSCR4 phospholipid scramblase 4 0.0070776
CFH complement factor H 0.00706648
IGFBP5 insulin-like growth factor binding protein 5 0.00705478
SNAI2 snail family zinc finger 2 0.00702836
LY96 lymphocyte antigen 96 0.00701847
SAR1B secretion associated, Ras related GTPase 1B 0.00700342
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00699624
IL20RA interleukin 20 receptor, alpha 0.0069763
DCT dopachrome tautomerase 0.00696751
C7 complement component 7 0.00695952
MCAM melanoma cell adhesion molecule 0.00688728
GEM GTP binding protein overexpressed in skeletal muscle 0.00688544
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00688129
CA2 carbonic anhydrase II 0.00687703
WASHC4 WASH complex subunit 4 0.00687348
EIF5A eukaryotic translation initiation factor 5A 0.00685921
THBS1 thrombospondin 1 0.00684558
PRAME preferentially expressed antigen in melanoma 0.00683468
KLK6 kallikrein-related peptidase 6 0.00683326
GPM6B glycoprotein M6B 0.00679995
BTN3A3 butyrophilin, subfamily 3, member A3 0.00679978
PLP1 proteolipid protein 1 0.00679963
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00677366
RRAGD Ras-related GTP binding D 0.00674365
ARL4A ADP-ribosylation factor-like 4A 0.00673245
LOR loricrin 0.00672867
FGFR1 fibroblast growth factor receptor 1 0.00670001
C3AR1 complement component 3a receptor 1 0.00669278
DPYD dihydropyrimidine dehydrogenase 0.00668568
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0066498
DLG5 discs, large homolog 5 (Drosophila) 0.00664649
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0066396
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.00663358
COLEC11 collectin sub-family member 11 0.00663004
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00658166
REG3A regenerating islet-derived 3 alpha 0.00657861
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00656171
AADAC arylacetamide deacetylase 0.00654022
BID BH3 interacting domain death agonist 0.00650792
CRIP2 cysteine-rich protein 2 0.00650246
AOX1 aldehyde oxidase 1 0.0064954
SARAF store-operated calcium entry-associated regulatory factor 0.00648353
KDM5D lysine (K)-specific demethylase 5D 0.0064686
S100P S100 calcium binding protein P 0.00646409
RGS5 regulator of G-protein signaling 5 0.00646281
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00641243
TFF1 trefoil factor 1 0.00639825
SPRR2B small proline-rich protein 2B 0.00638701
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0063704
IFI44 interferon-induced protein 44 0.00636206
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00632516
CCNB1 cyclin B1 0.00630661
F5 coagulation factor V (proaccelerin, labile factor) 0.0063014
APOC3 apolipoprotein C-III 0.00628076
MOCOS molybdenum cofactor sulfurase 0.00627655
TM4SF4 transmembrane 4 L six family member 4 0.00627577
TLR4 toll-like receptor 4 0.00627102
HIPK1 homeodomain interacting protein kinase 1 0.00625504
CD69 CD69 molecule 0.00624024
DPYSL3 dihydropyrimidinase-like 3 0.00623104
PPT2 palmitoyl-protein thioesterase 2 0.00621741
WIPF1 WAS/WASL interacting protein family, member 1 0.00620795
CST1 cystatin SN 0.00620269
ESD esterase D 0.00619455
VTN vitronectin 0.00615063
CRP C-reactive protein, pentraxin-related 0.00612473
IL1R2 interleukin 1 receptor, type II 0.0061015
GPR137B G protein-coupled receptor 137B 0.00609173
HTRA1 HtrA serine peptidase 1 0.00606825
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00606596
LGALS4 lectin, galactoside-binding, soluble, 4 0.00606047
LCN2 lipocalin 2 0.00605149
BTN3A2 butyrophilin, subfamily 3, member A2 0.00605122
MME membrane metallo-endopeptidase 0.00605122
RAB4A RAB4A, member RAS oncogene family 0.00604341
ECI2 enoyl-CoA delta isomerase 2 0.00600997
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.00597883
EVI2A ecotropic viral integration site 2A 0.00594958
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00594683
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00594586
CYB5A cytochrome b5 type A (microsomal) 0.00594277
ADAM28 ADAM metallopeptidase domain 28 0.00594125
SELL selectin L 0.00593336
GMFG glia maturation factor, gamma 0.00592945
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.00591816
C6ORF48 chromosome 6 open reading frame 48 0.00590893
GATA6 GATA binding protein 6 0.00590507
PLN phospholamban 0.0059016
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00589566
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00588231
S100A9 S100 calcium binding protein A9 0.00587709
KCTD3 potassium channel tetramerization domain containing 3 0.0058751
RNASET2 ribonuclease T2 0.00587502
TPH1 tryptophan hydroxylase 1 0.00587456
ACKR3 atypical chemokine receptor 3 0.0058711
COQ8A coenzyme Q8A 0.00584265
POF1B premature ovarian failure, 1B 0.00583422
UBE2D1 ubiquitin-conjugating enzyme E2D 1 0.00582643
PTDSS1 phosphatidylserine synthase 1 0.00582029
MMP12 matrix metallopeptidase 12 0.00581854
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00581216
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00580365
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.00580013
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0057929
MMD monocyte to macrophage differentiation-associated 0.00578835
RGS4 regulator of G-protein signaling 4 0.00578732
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00576298
OXA1L oxidase (cytochrome c) assembly 1-like 0.00575669
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00575154
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00574717
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00574361
RPS5 ribosomal protein S5 0.0057345
WFDC1 WAP four-disulfide core domain 1 0.00572547
DDT D-dopachrome tautomerase 0.00571547
GIMAP6 GTPase, IMAP family member 6 0.00571461
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00567074
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.00566927
INHBB inhibin, beta B 0.00566873
BIRC3 baculoviral IAP repeat containing 3 0.00566844
FDX1 ferredoxin 1 0.00566041
AKR1C3 aldo-keto reductase family 1, member C3 0.00565793
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.0056537
CRIP1 cysteine-rich protein 1 (intestinal) 0.00564619
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00563663
MRPS30 mitochondrial ribosomal protein S30 0.00563294
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00561961
NDN necdin, melanoma antigen (MAGE) family member 0.00561878
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00561763
NELL1 NEL-like 1 (chicken) 0.00561004
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 0.0056051
CD302 CD302 molecule 0.00559277
MPC1 mitochondrial pyruvate carrier 1 0.0055889
SEC31A SEC31 homolog A (S. cerevisiae) 0.00558424
MAOB monoamine oxidase B 0.00556637
IL13RA2 interleukin 13 receptor, alpha 2 0.00556167
CYTIP cytohesin 1 interacting protein 0.0055569
CDSN corneodesmosin 0.00555246
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00554674
ARHGAP15 Rho GTPase activating protein 15 0.00552934
ENOPH1 enolase-phosphatase 1 0.00550074
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00549404
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00549069
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00548533
LUM lumican 0.00548271
PRKCA protein kinase C, alpha 0.00548212
SLC16A6 solute carrier family 16, member 6 0.00546348
ANXA6 annexin A6 0.00545827
MMP11 matrix metallopeptidase 11 0.00545231

decreased expression

Symbol Name Standardized Value
KRT7 keratin 7, type II -0.0156008
TLCD3A TLC domain containing 3A -0.0139462
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.0134106
KRT19 keratin 19, type I -0.0130988
PTN pleiotrophin -0.0128388
SIRT3 sirtuin 3 -0.0127954
FBN2 fibrillin 2 -0.0117834
GNAS GNAS complex locus -0.0117465
CTSZ cathepsin Z -0.0108808
FOLR1 folate receptor 1 (adult) -0.0106235
KRT18 keratin 18, type I -0.0105899
TACSTD2 tumor-associated calcium signal transducer 2 -0.0105656
MT1E metallothionein 1E -0.0104833
CRABP2 cellular retinoic acid binding protein 2 -0.00984016
XIC X chromosome inactivation center -0.00982276
SFRP1 secreted frizzled-related protein 1 -0.00979049
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0094198
TFPI2 tissue factor pathway inhibitor 2 -0.00935722
SIX1 SIX homeobox 1 -0.00931215
ELN elastin -0.00926616
PEG10 paternally expressed 10 -0.00924713
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00914957
DIPK1A divergent protein kinase domain 1A -0.00914944
IL17RB interleukin 17 receptor B -0.00908777
TSPAN1 tetraspanin 1 -0.0090277
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00884428
SFTPA2 surfactant protein A2 -0.00853046
SFTPB surfactant protein B -0.00838119
KRT17 keratin 17, type I -0.00834261
XYLT1 xylosyltransferase I -0.00833972
PNMA2 paraneoplastic Ma antigen 2 -0.0083057
IFITM1 interferon induced transmembrane protein 1 -0.00828644
CDC20 cell division cycle 20 -0.00824825
MXRA7 matrix-remodelling associated 7 -0.00822977
FRS2 fibroblast growth factor receptor substrate 2 -0.00820245
PRODH proline dehydrogenase (oxidase) 1 -0.00818117
CAPG capping protein (actin filament), gelsolin-like -0.00814553
CD320 CD320 molecule -0.00807554
MMP7 matrix metallopeptidase 7 -0.00807185
HOXA11 homeobox A11 -0.00805665
OSBPL10 oxysterol binding protein-like 10 -0.00803919
MEF2C myocyte enhancer factor 2C -0.00800475
TCF4 transcription factor 4 -0.00797605
SMAD7 SMAD family member 7 -0.00777202
GSTP1 glutathione S-transferase pi 1 -0.00776382
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00770918
CDK14 cyclin-dependent kinase 14 -0.00760513
CD9 CD9 molecule -0.0075929
CIT citron rho-interacting serine/threonine kinase -0.00748092
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00747967
E2F2 E2F transcription factor 2 -0.00747029
RNF19B ring finger protein 19B -0.00747023
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00737098
PCNA proliferating cell nuclear antigen -0.00734974
AUTS2 autism susceptibility candidate 2 -0.00734509
CDCA4 cell division cycle associated 4 -0.00723008
PLAU plasminogen activator, urokinase -0.00722308
ATP13A3 ATPase type 13A3 -0.0071498
S100A2 S100 calcium binding protein A2 -0.00712691
HMGB1 high mobility group box 1 -0.00712259
PKM pyruvate kinase, muscle -0.00705981
LIMA1 LIM domain and actin binding 1 -0.00700689
CLDN4 claudin 4 -0.00699139
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -0.0069581
LY6E lymphocyte antigen 6 complex, locus E -0.00689885
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.00683093
IRX5 iroquois homeobox 5 -0.00677675
LMNB2 lamin B2 -0.00676571
CD151 CD151 molecule (Raph blood group) -0.00675451
PNMA8A PNMA family member 8A -0.00674063
HEATR1 HEAT repeat containing 1 -0.00670263
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00668686
IGFBP6 insulin-like growth factor binding protein 6 -0.00667563
EFNB2 ephrin-B2 -0.00665595
NLRP2 NLR family, pyrin domain containing 2 -0.00664751
ACTN4 actinin, alpha 4 -0.00663835
PTGES prostaglandin E synthase -0.00662615
DCK deoxycytidine kinase -0.00658422
FXYD5 FXYD domain containing ion transport regulator 5 -0.00648756
SEPTIN10 septin 10 -0.00648645
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00647749
HOXC10 homeobox C10 -0.00646489
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00641328
S100A11 S100 calcium binding protein A11 -0.00641317
OLFM1 olfactomedin 1 -0.00641219
RHOBTB2 Rho-related BTB domain containing 2 -0.00640843
METTL7A methyltransferase like 7A -0.00638979
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00635807
GPR107 G protein-coupled receptor 107 -0.00631463
MB myoglobin -0.00628022
CTPS1 CTP synthase 1 -0.00624344
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00620173
GSDME gasdermin E -0.00617082
UBE2H ubiquitin-conjugating enzyme E2H -0.00614625
RAB14 RAB14, member RAS oncogene family -0.00611661
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00608083
STK32B serine/threonine kinase 32B -0.00607789
TOX thymocyte selection-associated high mobility group box -0.00605276
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00602815
SLPI secretory leukocyte peptidase inhibitor -0.00599924
WFDC2 WAP four-disulfide core domain 2 -0.00596806
PDGFC platelet derived growth factor C -0.00595413
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00595028
PXDN peroxidasin -0.00593778
GNLY granulysin -0.00591987
TUBB4B tubulin, beta 4B class IVb -0.00591753
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00591654
CD81 CD81 molecule -0.00590734
BPGM 2,3-bisphosphoglycerate mutase -0.00590648
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00588282
HIST1H2BK histone cluster 1, H2bk -0.00586431
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00584725
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00584198
PRSS8 protease, serine, 8 -0.00582498
INAVA innate immunity activator -0.00579704
TRIP6 thyroid hormone receptor interactor 6 -0.00578192
MLF1 myeloid leukemia factor 1 -0.00577023
MT1F metallothionein 1F -0.00576143
SDC4 syndecan 4 -0.00575689
PRKCB protein kinase C, beta -0.00573167
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00572926
NT5DC2 5'-nucleotidase domain containing 2 -0.00571806
CADPS2 Ca++-dependent secretion activator 2 -0.00571581
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -0.005714
BMP2 bone morphogenetic protein 2 -0.0057119
GPX4 glutathione peroxidase 4 -0.00568651
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00563962
CAMK1 calcium/calmodulin-dependent protein kinase I -0.00563961
TUSC3 tumor suppressor candidate 3 -0.00563765
STEAP3 STEAP family member 3, metalloreductase -0.00562454
P3H2 prolyl 3-hydroxylase 2 -0.00561542
EHD3 EH-domain containing 3 -0.00559709
BIN1 bridging integrator 1 -0.0055662
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00555631
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00555138
STK38L serine/threonine kinase 38 like -0.00554858
ACAN aggrecan -0.00554063
CA11 carbonic anhydrase XI -0.00553149
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00553128
SMYD3 SET and MYND domain containing 3 -0.00552396
NMU neuromedin U -0.00548683
RABAC1 Rab acceptor 1 (prenylated) -0.0054832
TNNT1 troponin T type 1 (skeletal, slow) -0.00548242
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00548173
ARHGAP22 Rho GTPase activating protein 22 -0.00547641
TYMS thymidylate synthetase -0.00546962
TMEM41B transmembrane protein 41B -0.00546012
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.00544707
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00544282
IFITM3 interferon induced transmembrane protein 3 -0.00544274
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00544263
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00543865
CHRDL1 chordin-like 1 -0.00543088
FAM110B family with sequence similarity 110, member B -0.00542797
DRAM1 DNA-damage regulated autophagy modulator 1 -0.0054241
PRDX2 peroxiredoxin 2 -0.00541367
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00540422
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00537056
PDIA4 protein disulfide isomerase family A, member 4 -0.00536009
OPCML opioid binding protein/cell adhesion molecule-like -0.00535736
CEP70 centrosomal protein 70kDa -0.00535081
MAPK10 mitogen-activated protein kinase 10 -0.0053355
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.0053325
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00533047
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00532557
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -0.00531526
CD8A CD8a molecule -0.00529488
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00528914
CCND2 cyclin D2 -0.00528722
GLRB glycine receptor, beta -0.00525665
CRYAB crystallin, alpha B -0.00523567
SLC35E3 solute carrier family 35, member E3 -0.00522964
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.00521981
TSPAN13 tetraspanin 13 -0.00521633
GOLM1 golgi membrane protein 1 -0.00521512
MEAK7 MTOR associated protein, eak-7 homolog -0.00520746
IFITM2 interferon induced transmembrane protein 2 -0.00520226
DHDDS dehydrodolichyl diphosphate synthase -0.00517377
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00515595
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.00515201
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00514213
MT1H metallothionein 1H -0.00512847
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00512787
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.00512654
NBEA neurobeachin -0.00512289
RTN2 reticulon 2 -0.00510533
ZBTB38 zinc finger and BTB domain containing 38 -0.00509491
CTSB cathepsin B -0.00509366
PDE4A phosphodiesterase 4A, cAMP-specific -0.00509107
SEC62 SEC62 homolog (S. cerevisiae) -0.00508813
PTPRD protein tyrosine phosphatase, receptor type, D -0.00507678
TAOK3 TAO kinase 3 -0.00507548
TMEM259 transmembrane protein 259 -0.00504937
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.00504779
KIF2C kinesin family member 2C -0.00504613
LARS1 leucyl-tRNA synthetase 1 -0.00503674
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00502864
COBL cordon-bleu WH2 repeat protein -0.0050138
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.00501346
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00501338
PLD3 phospholipase D family, member 3 -0.00500549
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00498549
AKAP12 A kinase (PRKA) anchor protein 12 -0.00497444
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00496929
CBX5 chromobox homolog 5 -0.00496012
RRM1 ribonucleotide reductase M1 -0.00494372
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 -0.00492001
S100A6 S100 calcium binding protein A6 -0.0049173
SFTPC surfactant protein C -0.00490257
ERGIC2 ERGIC and golgi 2 -0.00489289
NYNRIN NYN domain and retroviral integrase containing -0.00488725
FEN1 flap structure-specific endonuclease 1 -0.00488652
ZNF22 zinc finger protein 22 -0.00488254
LITAF lipopolysaccharide-induced TNF factor -0.00487897
RUVBL2 RuvB-like AAA ATPase 2 -0.00487497
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00486923
BTG2 BTG family, member 2 -0.00486385
ZNF611 zinc finger protein 611 -0.00485768
TINAGL1 tubulointerstitial nephritis antigen-like 1 -0.00484265
GPX1 glutathione peroxidase 1 -0.00484096
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -0.0048387
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00483693
MCM6 minichromosome maintenance complex component 6 -0.0048333
EIF5B eukaryotic translation initiation factor 5B -0.00482943
VRK2 vaccinia related kinase 2 -0.00480963
ENG endoglin -0.00480233
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00479881
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -0.00479629
DUSP5 dual specificity phosphatase 5 -0.0047961
FAIM Fas apoptotic inhibitory molecule -0.00476736
WNT5B wingless-type MMTV integration site family, member 5B -0.00475362
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.00474749
OBSL1 obscurin-like 1 -0.00474322
UPK1B uroplakin 1B -0.00473183
AK1 adenylate kinase 1 -0.00472844
UBE2S ubiquitin-conjugating enzyme E2S -0.00472655
CSRNP2 cysteine-serine-rich nuclear protein 2 -0.00471983
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00471072
NME5 NME/NM23 family member 5 -0.00470931
MELK maternal embryonic leucine zipper kinase -0.00470877
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 -0.00470582
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00469997
PNKP polynucleotide kinase 3'-phosphatase -0.00469983
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -0.0046991
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -0.00468428
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00468426
CDH18 cadherin 18, type 2 -0.00466617
RBM47 RNA binding motif protein 47 -0.00466044