CLEC7A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description C-type lectin domain family 7, member A|This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 64581)
External Link https://ncbi.nlm.nih.gov/gene/64581
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Genes

497 genes differentially expressed following the CLEC7A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.0125594
MAGEA3 melanoma antigen family A3 0.0120396
WDR7 WD repeat domain 7 0.0114778
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.0105127
CHGB chromogranin B 0.0102432
SSBP2 single-stranded DNA binding protein 2 0.0101942
MX1 MX dynamin-like GTPase 1 0.0100894
IGFBP5 insulin-like growth factor binding protein 5 0.0097391
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00953232
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00927549
HSPB1 heat shock 27kDa protein 1 0.00910867
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00905336
IFI44 interferon-induced protein 44 0.00879228
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00869344
MAGEA12 melanoma antigen family A12 0.00863769
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00828485
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00818621
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00818103
ISG15 ISG15 ubiquitin-like modifier 0.00790337
MUC4 mucin 4, cell surface associated 0.00789977
KLK6 kallikrein-related peptidase 6 0.00785576
JUP junction plakoglobin 0.00783718
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00775153
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00775136
EDN3 endothelin 3 0.00772941
MYRF myelin regulatory factor 0.00767686
SEPP1 selenoprotein P, plasma, 1 0.00764994
MTUS1 microtubule associated tumor suppressor 1 0.00762828
MX2 MX dynamin-like GTPase 2 0.0075609
HOXB6 homeobox B6 0.0074313
NCOA3 nuclear receptor coactivator 3 0.00722586
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00722223
HOXC6 homeobox C6 0.00713409
COL15A1 collagen, type XV, alpha 1 0.0071097
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00707803
KLF6 Kruppel-like factor 6 0.00706245
IFI44L interferon-induced protein 44-like 0.00704421
TSPAN8 tetraspanin 8 0.00702826
HSPA2 heat shock 70kDa protein 2 0.00701352
RBBP4 retinoblastoma binding protein 4 0.00688392
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00686475
MBD2 methyl-CpG binding domain protein 2 0.00684927
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00682905
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00682589
MEN1 multiple endocrine neoplasia I 0.00678474
ITGA6 integrin, alpha 6 0.00673488
MAN1A1 mannosidase, alpha, class 1A, member 1 0.00662285
MAB21L2 mab-21-like 2 (C. elegans) 0.00662229
HOXB7 homeobox B7 0.00659805
L1CAM L1 cell adhesion molecule 0.00654181
KLK10 kallikrein-related peptidase 10 0.00652539
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00647716
FKBP5 FK506 binding protein 5 0.00646715
MYO1D myosin ID 0.00645147
DLK1 delta-like 1 homolog (Drosophila) 0.00641798
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00640697
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00638332
IVNS1ABP influenza virus NS1A binding protein 0.00630021
S100A7 S100 calcium binding protein A7 0.00628907
MLXIP MLX interacting protein 0.00621607
NEFM neurofilament, medium polypeptide 0.00619462
MME membrane metallo-endopeptidase 0.00618003
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00616368
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00615609
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00613428
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00612481
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0060986
STX1A syntaxin 1A (brain) 0.0060827
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00605616
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.00602831
HEPH hephaestin 0.00599367
MYH11 myosin, heavy chain 11, smooth muscle 0.00597256
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00596106
LASP1 LIM and SH3 protein 1 0.00595753
LIF leukemia inhibitory factor 0.00592396
QPRT quinolinate phosphoribosyltransferase 0.00591576
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00588693
PRPH peripherin 0.00587931
ITGB4 integrin, beta 4 0.00583909
ATF4 activating transcription factor 4 0.00581477
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00580664
JUNB jun B proto-oncogene 0.00580533
MVP major vault protein 0.00579935
CTSZ cathepsin Z 0.00576532
ELAVL1 ELAV like RNA binding protein 1 0.00575355
SERINC5 serine incorporator 5 0.00575004
ODAM odontogenic, ameloblast asssociated 0.00573255
SYT1 synaptotagmin I 0.00567762
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00564192
WFDC1 WAP four-disulfide core domain 1 0.00563829
DEFB1 defensin, beta 1 0.00563152
CD164 CD164 molecule, sialomucin 0.00562165
ETHE1 ethylmalonic encephalopathy 1 0.00555895
JADE2 jade family PHD finger 2 0.00550852
CXADR coxsackie virus and adenovirus receptor 0.00550225
AMDHD2 amidohydrolase domain containing 2 0.00549511
LGALS4 lectin, galactoside-binding, soluble, 4 0.0054668
GUCY2C guanylate cyclase 2C 0.00545729
RAB25 RAB25, member RAS oncogene family 0.00544071
PTBP2 polypyrimidine tract binding protein 2 0.00542923
TGFBR3 transforming growth factor, beta receptor III 0.00538981
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00536338
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00535943
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00535081
MAP2K6 mitogen-activated protein kinase kinase 6 0.00522669
CH25H cholesterol 25-hydroxylase 0.00522312
USP18 ubiquitin specific peptidase 18 0.00518339
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.00517087
RGCC regulator of cell cycle 0.00516502
A2M alpha-2-macroglobulin 0.0051648
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00515686
C9ORF3 chromosome 9 open reading frame 3 0.00514108
AGPS alkylglycerone phosphate synthase 0.00513991
RCAN2 regulator of calcineurin 2 0.00513394
GDE1 glycerophosphodiester phosphodiesterase 1 0.00511811
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.00509955
CLTB clathrin, light chain B 0.00509667
SMYD2 SET and MYND domain containing 2 0.00508779
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0050871
CNN1 calponin 1, basic, smooth muscle 0.00508229
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.00506132
PDZK1IP1 PDZK1 interacting protein 1 0.00505259
LDLR low density lipoprotein receptor 0.00505223
COL18A1 collagen, type XVIII, alpha 1 0.00505148
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00503296
ENO2 enolase 2 (gamma, neuronal) 0.0050297
TRH thyrotropin-releasing hormone 0.00501768
FDX1 ferredoxin 1 0.005017
PRSS21 protease, serine, 21 (testisin) 0.00499358
AKR1C2 aldo-keto reductase family 1, member C2 0.00498873
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00497206
BMERB1 bMERB domain containing 1 0.00496511
CLDN10 claudin 10 0.00496337
TM4SF4 transmembrane 4 L six family member 4 0.00495564
NID1 nidogen 1 0.00495269
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.00494961
OXA1L oxidase (cytochrome c) assembly 1-like 0.00492913
DCTN4 dynactin 4 (p62) 0.00491568
RHOA ras homolog family member A 0.00490918
FA2H fatty acid 2-hydroxylase 0.00490815
FLNA filamin A, alpha 0.00489844
PRAME preferentially expressed antigen in melanoma 0.00489611
PALLD palladin, cytoskeletal associated protein 0.00489171
DENND4C DENN/MADD domain containing 4C 0.0048888
MT2A metallothionein 2A 0.00488441
LY6D lymphocyte antigen 6 complex, locus D 0.00487293
ACTB actin, beta 0.00486474
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00486324
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00485892
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00485338
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.00483991
TESC tescalcin 0.00481396
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00481082
CHGA chromogranin A 0.00479372
INA internexin neuronal intermediate filament protein, alpha 0.00478838
TACC1 transforming, acidic coiled-coil containing protein 1 0.00478729
COL3A1 collagen, type III, alpha 1 0.00478673
HLA-B major histocompatibility complex, class I, B 0.00476786
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.0047452
PLIN3 perilipin 3 0.0047399
IFIH1 interferon induced with helicase C domain 1 0.00473788
EPS8L3 EPS8-like 3 0.00473435
RHCG Rh family, C glycoprotein 0.00472149
NCOR2 nuclear receptor corepressor 2 0.00470569
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.00468608
HDAC1 histone deacetylase 1 0.00468311
PLCL1 phospholipase C-like 1 0.00467249
EGR1 early growth response 1 0.00466894
PFKP phosphofructokinase, platelet 0.00466217
EMP1 epithelial membrane protein 1 0.00464705
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00462484
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00460764
ASF1B anti-silencing function 1B histone chaperone 0.00459596
MAL mal, T-cell differentiation protein 0.00459557
AKR1C1 aldo-keto reductase family 1, member C1 0.00459062
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00456549
ASS1 argininosuccinate synthase 1 0.00456378
ZFP36 ZFP36 ring finger protein 0.00456265
TNIP1 TNFAIP3 interacting protein 1 0.00454866
RTCA RNA 3'-terminal phosphate cyclase 0.00453893
FAM102A family with sequence similarity 102, member A 0.0045337
NT5E 5'-nucleotidase, ecto (CD73) 0.00453328
COMT catechol-O-methyltransferase 0.00453166
MKI67 marker of proliferation Ki-67 0.00451876
AK2 adenylate kinase 2 0.00451571
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00450205
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00449977
HP1BP3 heterochromatin protein 1, binding protein 3 0.00449709
UMOD uromodulin 0.00449618
AATF apoptosis antagonizing transcription factor 0.00448368
ANGPT1 angiopoietin 1 0.00448267
SNAP25 synaptosomal-associated protein, 25kDa 0.00448105
GAB2 GRB2-associated binding protein 2 0.00446879
EGR3 early growth response 3 0.00446293
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.00445491
TP53I3 tumor protein p53 inducible protein 3 0.00444911
ACAA2 acetyl-CoA acyltransferase 2 0.00444257
SATB2 SATB homeobox 2 0.00443836
BMP4 bone morphogenetic protein 4 0.00441094
TMPRSS4 transmembrane protease, serine 4 0.00441091
TUBB3 tubulin, beta 3 class III 0.00440614
NNT nicotinamide nucleotide transhydrogenase 0.00439958
PER1 period circadian clock 1 0.00439933
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00439236
CLDN8 claudin 8 0.00438316
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.00438286
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00437948
ZMAT3 zinc finger, matrin-type 3 0.00437217
RIMBP2 RIMS binding protein 2 0.00436927
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.00436823
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00436024
ALDOB aldolase B, fructose-bisphosphate 0.00435569
AKTIP AKT interacting protein 0.00434885
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00434537
IL15RA interleukin 15 receptor, alpha 0.00433176
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00432957
MAST4 microtubule associated serine/threonine kinase family member 4 0.00432936
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.00432022
BCL3 B-cell CLL/lymphoma 3 0.00430861
GMDS GDP-mannose 4,6-dehydratase 0.00430175
SCAMP1 secretory carrier membrane protein 1 0.00429302
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00429141
FAM198B family with sequence similarity 198, member B 0.0042911
FAF1 Fas (TNFRSF6) associated factor 1 0.00427614
RCAN1 regulator of calcineurin 1 0.00427383
CAPNS1 calpain, small subunit 1 0.00426747
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.00426425
PFKL phosphofructokinase, liver 0.00426093
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.004239
KLK11 kallikrein-related peptidase 11 0.00423806
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.00422981
GBP2 guanylate binding protein 2, interferon-inducible 0.00422771
CIZ1 CDKN1A interacting zinc finger protein 1 0.00422504
PHF11 PHD finger protein 11 0.00422061
MUC13 mucin 13, cell surface associated 0.00420587
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00420266
DNM1L dynamin 1-like 0.00420047
ACVR1B activin A receptor, type IB 0.00418741
MED6 mediator complex subunit 6 0.00417523
KIF3B kinesin family member 3B 0.00416336
TPM4 tropomyosin 4 0.00415911
EIF3K eukaryotic translation initiation factor 3, subunit K 0.00415631
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00414937
MAOA monoamine oxidase A 0.00413373
DES desmin 0.00413172
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00413068
TUBB2A tubulin, beta 2A class IIa 0.00412822
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00411996
AIM2 absent in melanoma 2 0.00411793

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0128455
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0122024
GPX1 glutathione peroxidase 1 -0.0111865
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.010782
CD320 CD320 molecule -0.010702
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0103255
ADIRF adipogenesis regulatory factor -0.010164
IL7R interleukin 7 receptor -0.0100683
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00983526
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00980658
S100A8 S100 calcium binding protein A8 -0.00978705
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00943557
NIBAN1 niban apoptosis regulator 1 -0.00923968
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00858836
TSPAN13 tetraspanin 13 -0.0085739
TARP TCR gamma alternate reading frame protein -0.00846598
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00834765
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00822389
G0S2 G0/G1 switch 2 -0.00803672
IDO1 indoleamine 2,3-dioxygenase 1 -0.0079899
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00797448
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00792625
CPA3 carboxypeptidase A3 (mast cell) -0.00791679
CLU clusterin -0.00784056
SDCBP syndecan binding protein (syntenin) -0.00774304
GZMK granzyme K (granzyme 3; tryptase II) -0.00763102
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00757329
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00753787
P3H2 prolyl 3-hydroxylase 2 -0.00743929
FTH1 ferritin, heavy polypeptide 1 -0.00740615
TFPI2 tissue factor pathway inhibitor 2 -0.00737696
AUTS2 autism susceptibility candidate 2 -0.00733977
GSPT2 G1 to S phase transition 2 -0.00731603
BASP1 brain abundant, membrane attached signal protein 1 -0.0072225
STK26 serine/threonine protein kinase 26 -0.00709205
ZBTB18 zinc finger and BTB domain containing 18 -0.0070505
ANXA3 annexin A3 -0.00704917
MXRA7 matrix-remodelling associated 7 -0.00696086
APMAP adipocyte plasma membrane associated protein -0.00693195
MMP9 matrix metallopeptidase 9 -0.00690576
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00688065
PHACTR2 phosphatase and actin regulator 2 -0.0067936
MMP1 matrix metallopeptidase 1 -0.00674318
CSRP2 cysteine and glycine-rich protein 2 -0.0066956
SOX11 SRY (sex determining region Y)-box 11 -0.00667327
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00665102
ZBTB20 zinc finger and BTB domain containing 20 -0.00663161
PTN pleiotrophin -0.00651868
GSTM3 glutathione S-transferase mu 3 (brain) -0.00643276
GPX3 glutathione peroxidase 3 -0.00642923
COMP cartilage oligomeric matrix protein -0.00638978
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00635825
EMP3 epithelial membrane protein 3 -0.0063094
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00619673
ADD3 adducin 3 (gamma) -0.00608119
CSTA cystatin A (stefin A) -0.00606433
CLIC3 chloride intracellular channel 3 -0.00604281
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00602732
JCHAIN joining chain of multimeric IgA and IgM -0.00600981
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00599894
NOTCH2NL notch 2 N-terminal like -0.00598243
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00596463
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00596314
FSTL1 follistatin-like 1 -0.00591577
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00591191
GDF15 growth differentiation factor 15 -0.00587146
BCL2A1 BCL2-related protein A1 -0.00587112
SLC38A1 solute carrier family 38, member 1 -0.00585127
CD69 CD69 molecule -0.0058421
ADAM9 ADAM metallopeptidase domain 9 -0.00583061
STC2 stanniocalcin 2 -0.00583048
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00580184
NPY1R neuropeptide Y receptor Y1 -0.00579698
C1ORF54 chromosome 1 open reading frame 54 -0.00577383
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00573562
DCK deoxycytidine kinase -0.00572016
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00568018
RPA3 replication protein A3, 14kDa -0.00567142
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0056532
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00565124
PAQR3 progestin and adipoQ receptor family member III -0.00564561
PF4 platelet factor 4 -0.00562274
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00558223
LRRC17 leucine rich repeat containing 17 -0.00555903
INTS6 integrator complex subunit 6 -0.0055269
MOK MOK protein kinase -0.00549715
CCL19 chemokine (C-C motif) ligand 19 -0.00548744
ZBTB38 zinc finger and BTB domain containing 38 -0.00548189
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00545404
TIPRL TOR signaling pathway regulator -0.00544854
LST1 leukocyte specific transcript 1 -0.00544578
SCAND1 SCAN domain containing 1 -0.00544396
CPB1 carboxypeptidase B1 (tissue) -0.00542638
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00540799
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.00540157
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00539231
TPSAB1 tryptase alpha/beta 1 -0.00536638
TMEM254 transmembrane protein 254 -0.00534189
PAK1IP1 PAK1 interacting protein 1 -0.00532618
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00531871
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00531343
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00529693
DACH1 dachshund family transcription factor 1 -0.00528469
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00528451
TYROBP TYRO protein tyrosine kinase binding protein -0.00527702
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.0052759
TOB1 transducer of ERBB2, 1 -0.00527242
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.00525924
NPC2 Niemann-Pick disease, type C2 -0.00522739
CD8A CD8a molecule -0.00520641
HAUS3 HAUS augmin-like complex, subunit 3 -0.00520443
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00520145
CCL5 chemokine (C-C motif) ligand 5 -0.0052006
LAPTM4A lysosomal protein transmembrane 4 alpha -0.00519388
PLS3 plastin 3 -0.00518916
PDIA3 protein disulfide isomerase family A, member 3 -0.0051756
CLGN calmegin -0.00516869
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00516765
ELOVL5 ELOVL fatty acid elongase 5 -0.00516473
LY96 lymphocyte antigen 96 -0.00516401
SLC16A4 solute carrier family 16, member 4 -0.00515533
TRIP6 thyroid hormone receptor interactor 6 -0.00515391
PLEK pleckstrin -0.00515232
FXYD1 FXYD domain containing ion transport regulator 1 -0.00513793
NKG7 natural killer cell granule protein 7 -0.00513595
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0051207
PARK7 parkinson protein 7 -0.0051181
OAT ornithine aminotransferase -0.00511553
HMGN5 high mobility group nucleosome binding domain 5 -0.00511241
LGMN legumain -0.00510762
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.00507299
CST7 cystatin F (leukocystatin) -0.00506427
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00506399
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.005063
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00502988
KRT19 keratin 19, type I -0.0050192
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00500467
PTPRK protein tyrosine phosphatase, receptor type, K -0.00499267
GPR183 G protein-coupled receptor 183 -0.00498672
TAGLN transgelin -0.00497295
CPVL carboxypeptidase, vitellogenic-like -0.00497228
CYBA cytochrome b-245, alpha polypeptide -0.00497022
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00492255
VCAM1 vascular cell adhesion molecule 1 -0.00490098
LRRC15 leucine rich repeat containing 15 -0.00489364
NOTCH2 notch 2 -0.00488903
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00488084
C12ORF29 chromosome 12 open reading frame 29 -0.00487738
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00487556
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00486419
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -0.00483673
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.0048309
SDS serine dehydratase -0.00481192
GSAP gamma-secretase activating protein -0.00479452
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0047932
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0047873
RPS5 ribosomal protein S5 -0.00476549
GPNMB glycoprotein (transmembrane) nmb -0.00476179
DBF4 DBF4 zinc finger -0.00475245
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00473496
SELL selectin L -0.0047318
ARHGAP29 Rho GTPase activating protein 29 -0.00472908
KRT5 keratin 5, type II -0.00472681
ICAM2 intercellular adhesion molecule 2 -0.00472289
BEX1 brain expressed, X-linked 1 -0.00470513
PFKM phosphofructokinase, muscle -0.00467417
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00466382
PLAAT3 phospholipase A and acyltransferase 3 -0.0046504
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00464421
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00463952
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00463167
CNTN1 contactin 1 -0.00462364
ZNF587 zinc finger protein 587 -0.00461377
LPAR1 lysophosphatidic acid receptor 1 -0.00460566
PLIN1 perilipin 1 -0.00460421
IRX5 iroquois homeobox 5 -0.00460005
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00458932
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00458587
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00457521
NXF3 nuclear RNA export factor 3 -0.00457433
TSPYL5 TSPY-like 5 -0.00456826
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.004567
PRKCZ protein kinase C, zeta -0.00455476
NANOG Nanog homeobox -0.00455445
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.00454539
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -0.00452652
ZNHIT1 zinc finger, HIT-type containing 1 -0.00452123
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00451534
FGFR3 fibroblast growth factor receptor 3 -0.00448919
ENO3 enolase 3 (beta, muscle) -0.00446104
CLEC7A C-type lectin domain family 7, member A -0.00445971
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.00445599
GGT1 gamma-glutamyltransferase 1 -0.00442035
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0044197
ATP13A3 ATPase type 13A3 -0.00441554
LYPLA1 lysophospholipase I -0.00441543
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -0.00440279
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.00440016
MT1M metallothionein 1M -0.00439895
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00438855
CD300A CD300a molecule -0.00438494
ZNF264 zinc finger protein 264 -0.00437885
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00437464
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00436716
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00435884
CRY1 cryptochrome circadian clock 1 -0.00434621
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00434403
C3ORF14 chromosome 3 open reading frame 14 -0.00433692
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00433675
EIF5A eukaryotic translation initiation factor 5A -0.00433198
PTK2B protein tyrosine kinase 2 beta -0.00432921
AXL AXL receptor tyrosine kinase -0.00432214
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.00432207
GJA1 gap junction protein, alpha 1, 43kDa -0.00431706
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00431304
MFAP2 microfibrillar-associated protein 2 -0.00430805
PTHLH parathyroid hormone-like hormone -0.00430248
BBX bobby sox homolog (Drosophila) -0.00430087
THBD thrombomodulin -0.00429979
TNNT1 troponin T type 1 (skeletal, slow) -0.00429107
ANXA10 annexin A10 -0.004278
BAD BCL2-associated agonist of cell death -0.00426564
NADK NAD kinase -0.0042587
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.00425204
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -0.00425089
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -0.0042397
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00423583
RPL26L1 ribosomal protein L26-like 1 -0.00423164
SRI sorcin -0.00423108
FBXO11 F-box protein 11 -0.00422936
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00421843
MCTP1 multiple C2 domains, transmembrane 1 -0.00421245
DSE dermatan sulfate epimerase -0.0042062
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00417982
PDLIM5 PDZ and LIM domain 5 -0.00417889
SNX6 sorting nexin 6 -0.00416963
ACTA1 actin, alpha 1, skeletal muscle -0.00416811
WARS1 tryptophanyl-tRNA synthetase 1 -0.0041652
RAB5IF RAB5 interacting factor -0.00416141
EREG epiregulin -0.00414894
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0041355
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00413266
SEH1L SEH1-like (S. cerevisiae) -0.0041244
RECK reversion-inducing-cysteine-rich protein with kazal motifs -0.00412368
PPIF peptidylprolyl isomerase F -0.00412258
RIDA reactive intermediate imine deaminase A homolog -0.00412232
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00412118
VAV3 vav 3 guanine nucleotide exchange factor -0.00412068