CLEMASTINE Gene Set

Dataset	DGIdb Drug Targets 2026
Category	physical interactions
Type	drug
Description	2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions. (Chemical Entities of Biological Interest Ontology, CHEBI_3738)
External Link	https://dgidb.org/results?searchType=drug&searchTerms=CLEMASTINE
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Genes

9 interacting proteins for the CLEMASTINE drug from theDGIdb Drug Targets 2026 dataset.

Symbol	Name	Standardized Value
P2RX7	purinergic receptor P2X, ligand gated ion channel, 7	0.18972
HRH1	histamine receptor H1	0.121893
THPO	thrombopoietin	0.0763809
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.0269786
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.0201415
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.0192515
TP53	tumor protein p53	0.0127855
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.0123298
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.00663807