| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ceroid-lipofuscinosis, neuronal 3|This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1201) |
| External Link | https://ncbi.nlm.nih.gov/gene/1201 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CLN3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.016694 |
| CLU | clusterin | 0.0124689 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0118439 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.0107395 |
| ANXA3 | annexin A3 | 0.0107389 |
| LTA4H | leukotriene A4 hydrolase | 0.0106998 |
| WASHC4 | WASH complex subunit 4 | 0.0103224 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00999804 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00983425 |
| SELL | selectin L | 0.00970596 |
| HHEX | hematopoietically expressed homeobox | 0.00963216 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00955883 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.0094759 |
| CAV2 | caveolin 2 | 0.0094032 |
| STOM | stomatin | 0.00937893 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00930798 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00927452 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00905657 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00879827 |
| ACTB | actin, beta | 0.0087598 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00873943 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00870511 |
| NEBL | nebulette | 0.00868841 |
| OPHN1 | oligophrenin 1 | 0.00856595 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00850513 |
| FGF13 | fibroblast growth factor 13 | 0.00835965 |
| TLR4 | toll-like receptor 4 | 0.00835284 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00828916 |
| COG7 | component of oligomeric golgi complex 7 | 0.00824122 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 0.0082234 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00821519 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00819132 |
| BEX1 | brain expressed, X-linked 1 | 0.0081503 |
| LTF | lactotransferrin | 0.00814264 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00808785 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00806631 |
| ZNF652 | zinc finger protein 652 | 0.00792494 |
| MT1H | metallothionein 1H | 0.00788422 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00780177 |
| PRDX2 | peroxiredoxin 2 | 0.00780004 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00776975 |
| CTSS | cathepsin S | 0.00768019 |
| TADA2A | transcriptional adaptor 2A | 0.0076461 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00764124 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00763176 |
| RHOB | ras homolog family member B | 0.00762789 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00761749 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00761599 |
| KRT1 | keratin 1, type II | 0.00748857 |
| DNTT | DNA nucleotidylexotransferase | 0.00743912 |
| COMMD10 | COMM domain containing 10 | 0.00743723 |
| MPO | myeloperoxidase | 0.00742533 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00741883 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00740921 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00739225 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00738673 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00735672 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.00735481 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00732793 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00730532 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00729546 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00726941 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.00722672 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00717396 |
| TSPAN31 | tetraspanin 31 | 0.00717203 |
| S100A7 | S100 calcium binding protein A7 | 0.00713761 |
| MRPL33 | mitochondrial ribosomal protein L33 | 0.00709382 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00699782 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00699438 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00698813 |
| CTSG | cathepsin G | 0.00696736 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.0069585 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00687265 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.0068586 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00685607 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00684879 |
| IL18 | interleukin 18 | 0.00682615 |
| XPO7 | exportin 7 | 0.00681873 |
| CTSC | cathepsin C | 0.00681501 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00678337 |
| BMP4 | bone morphogenetic protein 4 | 0.00678192 |
| TG | thyroglobulin | 0.00665824 |
| CA9 | carbonic anhydrase IX | 0.00659647 |
| TARP | TCR gamma alternate reading frame protein | 0.00650643 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00649828 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0064892 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00648781 |
| NKX2-1 | NK2 homeobox 1 | 0.0064715 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00646211 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00644863 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00641275 |
| MT2A | metallothionein 2A | 0.00641076 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00640933 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00640713 |
| SRP72 | signal recognition particle 72kDa | 0.00640493 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00637444 |
| EDN3 | endothelin 3 | 0.00637397 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00636944 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00634765 |
| MT1G | metallothionein 1G | 0.00627793 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 | 0.00627196 |
| CDC42 | cell division cycle 42 | 0.00626424 |
| MAL | mal, T-cell differentiation protein | 0.00626401 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00626232 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00625492 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00623882 |
| ELANE | elastase, neutrophil expressed | 0.00623637 |
| SCEL | sciellin | 0.00623392 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00622522 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00622021 |
| GAP43 | growth associated protein 43 | 0.00620349 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.0061779 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00617052 |
| PLA2G2D | phospholipase A2, group IID | 0.00615712 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00615351 |
| NMB | neuromedin B | 0.00615106 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.00613514 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00612114 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00612083 |
| RPL36AL | ribosomal protein L36a-like | 0.00610028 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00609967 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00608476 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00607482 |
| CCNG1 | cyclin G1 | 0.00606845 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00606774 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00606356 |
| FZD6 | frizzled class receptor 6 | 0.00605874 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.0060561 |
| SFTPA2 | surfactant protein A2 | 0.00605038 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00604164 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00604064 |
| CNPY2 | canopy FGF signaling regulator 2 | 0.0060406 |
| STX1A | syntaxin 1A (brain) | 0.00603825 |
| F2R | coagulation factor II (thrombin) receptor | 0.00601914 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00601865 |
| DAZAP2 | DAZ associated protein 2 | 0.00600916 |
| CD53 | CD53 molecule | 0.00600717 |
| RPS26 | ribosomal protein S26 | 0.00600511 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00600219 |
| AIM2 | absent in melanoma 2 | 0.00599928 |
| GPR171 | G protein-coupled receptor 171 | 0.00598892 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00597351 |
| TGM2 | transglutaminase 2 | 0.00597217 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00596921 |
| RPL36 | ribosomal protein L36 | 0.0059542 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00594016 |
| ZNF430 | zinc finger protein 430 | 0.00593027 |
| ABHD17B | abhydrolase domain containing 17B | 0.00591196 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00589358 |
| SPRR1B | small proline-rich protein 1B | 0.00588954 |
| MYO5C | myosin VC | 0.00584939 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00582871 |
| MT1E | metallothionein 1E | 0.00581714 |
| QDPR | quinoid dihydropteridine reductase | 0.00580574 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00580536 |
| LYZ | lysozyme | 0.00578376 |
| PDE8B | phosphodiesterase 8B | 0.00578196 |
| RHOA | ras homolog family member A | 0.00578064 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.00577928 |
| RELN | reelin | 0.00577863 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00577012 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00576485 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0057627 |
| WDR7 | WD repeat domain 7 | 0.00574916 |
| JADE1 | jade family PHD finger 1 | 0.00573938 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00571449 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00570765 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00570577 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.00570533 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0056952 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00569295 |
| TMEM230 | transmembrane protein 230 | 0.0056732 |
| LY86 | lymphocyte antigen 86 | 0.00567306 |
| PLPBP | pyridoxal phosphate binding protein | 0.00566653 |
| SET | SET nuclear proto-oncogene | 0.00566344 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00566144 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00565633 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00565508 |
| GPR65 | G protein-coupled receptor 65 | 0.00564592 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.0056415 |
| ANOS1 | anosmin 1 | 0.00563663 |
| DENND4C | DENN/MADD domain containing 4C | 0.00563282 |
| OSMR | oncostatin M receptor | 0.00560803 |
| PRKCQ | protein kinase C, theta | 0.00559271 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00558593 |
| MZT2A | mitotic spindle organizing protein 2A | 0.00558445 |
| FOXE1 | forkhead box E1 | 0.00557801 |
| EPAS1 | endothelial PAS domain protein 1 | 0.005559 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00555323 |
| HOPX | HOP homeobox | 0.00554351 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | 0.00553794 |
| RIOX2 | ribosomal oxygenase 2 | 0.00553284 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00553167 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00552149 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00551947 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00551918 |
| SFTPB | surfactant protein B | 0.00551912 |
| PRMT1 | protein arginine methyltransferase 1 | 0.0055168 |
| MED6 | mediator complex subunit 6 | 0.00551185 |
| IL32 | interleukin 32 | 0.0054997 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00549491 |
| RDX | radixin | 0.00549429 |
| EHBP1 | EH domain binding protein 1 | 0.00548901 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.00548896 |
| PITX1 | paired-like homeodomain 1 | 0.00547667 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00547035 |
| CD48 | CD48 molecule | 0.00546944 |
| UTRN | utrophin | 0.00546336 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00544395 |
| SIRPG | signal-regulatory protein gamma | 0.0054397 |
| DMTN | dematin actin binding protein | 0.00543569 |
| EXOC5 | exocyst complex component 5 | 0.00542428 |
| HLA-F-AS1 | HLA-F antisense RNA 1 | 0.00541637 |
| TRIM16 | tripartite motif containing 16 | 0.00540803 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00540609 |
| DCTN4 | dynactin 4 (p62) | 0.00540567 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00540348 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00537586 |
| DEFB4A | defensin, beta 4A | 0.00532177 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00532118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00530352 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00530248 |
| MKI67 | marker of proliferation Ki-67 | 0.00528946 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.0052865 |
| FOCAD | focadhesin | 0.00528279 |
| MRPS18B | mitochondrial ribosomal protein S18B | 0.00527517 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00525868 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00525368 |
| DIXDC1 | DIX domain containing 1 | 0.0052536 |
| PDAP1 | PDGFA associated protein 1 | 0.00525227 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0052501 |
| PON3 | paraoxonase 3 | 0.0052489 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 0.00524432 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00524056 |
| MDFIC | MyoD family inhibitor domain containing | 0.00522811 |
| CNN2 | calponin 2 | 0.00522143 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00521836 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00521501 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.00521363 |
| NUP37 | nucleoporin 37kDa | 0.0052128 |
| SFTPC | surfactant protein C | 0.00521127 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00521033 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00520624 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.0052051 |
| FAM198B | family with sequence similarity 198, member B | 0.00520233 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00518659 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00518248 |
| PLP1 | proteolipid protein 1 | 0.00516829 |
| RPS27L | ribosomal protein S27-like | 0.00516648 |
| ACP1 | acid phosphatase 1, soluble | 0.00514444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0166488 |
| COPS7A | COP9 signalosome subunit 7A | -0.0144036 |
| COMP | cartilage oligomeric matrix protein | -0.0132745 |
| SNAI2 | snail family zinc finger 2 | -0.0129231 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0127294 |
| MX1 | MX dynamin-like GTPase 1 | -0.0125027 |
| KRT19 | keratin 19, type I | -0.0119733 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.0119092 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0118199 |
| HSPA2 | heat shock 70kDa protein 2 | -0.011784 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0115501 |
| G0S2 | G0/G1 switch 2 | -0.01126 |
| APOD | apolipoprotein D | -0.0110943 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0110112 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0109036 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0108879 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0108297 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0108007 |
| INHBA | inhibin, beta A | -0.0106598 |
| HTRA1 | HtrA serine peptidase 1 | -0.0105221 |
| WT1 | Wilms tumor 1 | -0.0104368 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.0104226 |
| PLAT | plasminogen activator, tissue | -0.010224 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0102233 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.010188 |
| TOB1 | transducer of ERBB2, 1 | -0.0100452 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0098348 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00963995 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00956767 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.0094655 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00936963 |
| GAS1 | growth arrest-specific 1 | -0.00935581 |
| KRT5 | keratin 5, type II | -0.00927089 |
| FST | follistatin | -0.00924988 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00912284 |
| SIK1 | salt-inducible kinase 1 | -0.00899082 |
| DIPK1A | divergent protein kinase domain 1A | -0.00892575 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.0089243 |
| KRT23 | keratin 23, type I | -0.00889532 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00885383 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00876259 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00872941 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00870847 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00869601 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00859647 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00858037 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00853792 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00849379 |
| BRD4 | bromodomain containing 4 | -0.00849257 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00847814 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00845442 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.008427 |
| TXLNA | taxilin alpha | -0.00838833 |
| ZIC1 | Zic family member 1 | -0.00836599 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00835525 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0083407 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00827469 |
| SIKE1 | suppressor of IKBKE 1 | -0.008194 |
| ANXA4 | annexin A4 | -0.00818311 |
| CD9 | CD9 molecule | -0.00814357 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00812341 |
| IL1R1 | interleukin 1 receptor, type I | -0.00811641 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00811289 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00806184 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00804967 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00794712 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00792521 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0079016 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00787733 |
| CCND2 | cyclin D2 | -0.00785523 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00782606 |
| AEBP1 | AE binding protein 1 | -0.00771937 |
| CTSK | cathepsin K | -0.00768901 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00768432 |
| ANGPTL2 | angiopoietin-like 2 | -0.00768224 |
| LMNA | lamin A/C | -0.00765683 |
| HOXC10 | homeobox C10 | -0.00760508 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00759984 |
| INAVA | innate immunity activator | -0.00756879 |
| IFI44 | interferon-induced protein 44 | -0.00753037 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00745659 |
| MAP7 | microtubule-associated protein 7 | -0.00735319 |
| MFAP5 | microfibrillar associated protein 5 | -0.00735081 |
| TRIB2 | tribbles pseudokinase 2 | -0.00733187 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00731388 |
| STK26 | serine/threonine protein kinase 26 | -0.0072631 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00724436 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00720867 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00712256 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00711799 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.0071008 |
| DOCK4 | dedicator of cytokinesis 4 | -0.00709331 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00709162 |
| TES | testin LIM domain protein | -0.00705044 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00697865 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00696871 |
| PEX5 | peroxisomal biogenesis factor 5 | -0.0069134 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00686798 |
| STAG2 | stromal antigen 2 | -0.00685944 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.0068547 |
| EPYC | epiphycan | -0.00684828 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00684356 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00684 |
| TSPAN8 | tetraspanin 8 | -0.00681984 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00678966 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.00675776 |
| EFHD1 | EF-hand domain family, member D1 | -0.00675217 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.0067378 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.0067321 |
| MARCKSL1 | MARCKS-like 1 | -0.00672117 |
| NOTCH1 | notch 1 | -0.00671958 |
| MXRA5 | matrix-remodelling associated 5 | -0.00671527 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00670753 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00668387 |
| TARDBP | TAR DNA binding protein | -0.00662251 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00661176 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0066099 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00660653 |
| HIP1R | huntingtin interacting protein 1 related | -0.00657914 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00656281 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00654031 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.00650772 |
| YBX3 | Y box binding protein 3 | -0.00650122 |
| THBS4 | thrombospondin 4 | -0.00650042 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00649928 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00648158 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00648142 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0064546 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00644239 |
| IRF9 | interferon regulatory factor 9 | -0.0064248 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00642471 |
| GPR137B | G protein-coupled receptor 137B | -0.00641649 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0064147 |
| ELN | elastin | -0.00641211 |
| H1-2 | H1.2 linker histone, cluster member | -0.0064055 |
| ZNF395 | zinc finger protein 395 | -0.00640229 |
| CCDC69 | coiled-coil domain containing 69 | -0.0063918 |
| TMEM41B | transmembrane protein 41B | -0.00637584 |
| BRD2 | bromodomain containing 2 | -0.00636342 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00636253 |
| TSPYL5 | TSPY-like 5 | -0.00635495 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00635116 |
| RTN2 | reticulon 2 | -0.00631397 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00630546 |
| MMP19 | matrix metallopeptidase 19 | -0.00625957 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0062542 |
| MIR22HG | MIR22 host gene | -0.00624519 |
| PLLP | plasmolipin | -0.00623565 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00619808 |
| THBS1 | thrombospondin 1 | -0.00619263 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00618897 |
| VEGFA | vascular endothelial growth factor A | -0.00617078 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00616416 |
| PMM1 | phosphomannomutase 1 | -0.00615817 |
| PRKCZ | protein kinase C, zeta | -0.00615729 |
| CDC7 | cell division cycle 7 | -0.00615189 |
| GAS6 | growth arrest-specific 6 | -0.00611481 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00610366 |
| NPEPL1 | aminopeptidase-like 1 | -0.00608866 |
| MMP10 | matrix metallopeptidase 10 | -0.00606899 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00605329 |
| LCN2 | lipocalin 2 | -0.00604349 |
| S100P | S100 calcium binding protein P | -0.00604279 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00604112 |
| FBLN2 | fibulin 2 | -0.00603996 |
| LEFTY1 | left-right determination factor 1 | -0.00602682 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00599994 |
| PRKCI | protein kinase C, iota | -0.00597952 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00596106 |
| TOX3 | TOX high mobility group box family member 3 | -0.00596001 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00593937 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00593834 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00592845 |
| KIF5B | kinesin family member 5B | -0.0058959 |
| AHR | aryl hydrocarbon receptor | -0.00589312 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00589121 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00588269 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00587265 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.005871 |
| MMP9 | matrix metallopeptidase 9 | -0.00586974 |
| TPD52L2 | tumor protein D52-like 2 | -0.00583801 |
| RNF19B | ring finger protein 19B | -0.00582533 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.00581794 |
| GHR | growth hormone receptor | -0.00581516 |
| IRF7 | interferon regulatory factor 7 | -0.00579556 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | -0.00576975 |
| PKP2 | plakophilin 2 | -0.00576574 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00576364 |
| TPP2 | tripeptidyl peptidase II | -0.00575762 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00575053 |
| PDE10A | phosphodiesterase 10A | -0.00574912 |
| WASF1 | WAS protein family, member 1 | -0.00573526 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00573129 |
| KIF13B | kinesin family member 13B | -0.00572325 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00570732 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00570037 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.005696 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.00569556 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00569215 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00568818 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00567948 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00566326 |
| IFI44L | interferon-induced protein 44-like | -0.00564801 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00564544 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00564305 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00564184 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00564091 |
| KIAA0930 | KIAA0930 | -0.00563713 |
| EMP1 | epithelial membrane protein 1 | -0.00563565 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00563374 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00563267 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00562633 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0056255 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00559485 |
| PLXNA1 | plexin A1 | -0.00559448 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00558289 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00556554 |
| GSDMB | gasdermin B | -0.00555726 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00552986 |
| IL6 | interleukin 6 | -0.00551775 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00551353 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00550709 |
| IPO13 | importin 13 | -0.00549231 |
| PROM1 | prominin 1 | -0.00547897 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.0054733 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00547289 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00546961 |
| MMP11 | matrix metallopeptidase 11 | -0.00544704 |
| RAB21 | RAB21, member RAS oncogene family | -0.00543706 |
| PTN | pleiotrophin | -0.00543363 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.0054229 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00540404 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00540018 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00539826 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00539824 |
| KLHL21 | kelch-like family member 21 | -0.00538012 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00537689 |
| KRT14 | keratin 14, type I | -0.00537669 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00537637 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00537213 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00535797 |
| REG1B | regenerating islet-derived 1 beta | -0.00535766 |
| PMP22 | peripheral myelin protein 22 | -0.00535483 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00535362 |
| AOC1 | amine oxidase, copper containing 1 | -0.00534835 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00533541 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00533031 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00532863 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00532154 |
