CLN3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ceroid-lipofuscinosis, neuronal 3|This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1201)
External Link http://www.ncbi.nlm.nih.gov/gene/1201
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Genes

92 interacting proteins for CLN3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ADGRL2 adhesion G protein-coupled receptor L2
AFG3L2 AFG3-like AAA ATPase 2
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARMC6 armadillo repeat containing 6
ATG7 autophagy related 7
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
AUP1 ancient ubiquitous protein 1
C19ORF70 chromosome 19 open reading frame 70
CALU calumenin
CAND1 cullin-associated and neddylation-dissociated 1
CCDC47 coiled-coil domain containing 47
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CKAP4 cytoskeleton-associated protein 4
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPT1A carnitine palmitoyltransferase 1A (liver)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYC1 cytochrome c-1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
ERLIN2 ER lipid raft associated 2
ESYT2 extended synaptotagmin-like protein 2
FADS2 fatty acid desaturase 2
FANCI Fanconi anemia, complementation group I
FAR1 fatty acyl CoA reductase 1
FKBP8 FK506 binding protein 8, 38kDa
GANAB glucosidase, alpha; neutral AB
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GEMIN4 gem (nuclear organelle) associated protein 4
HACD3 3-hydroxyacyl-CoA dehydratase 3
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
ILVBL ilvB (bacterial acetolactate synthase)-like
IMMT inner membrane protein, mitochondrial
IRAK1 interleukin-1 receptor-associated kinase 1
KCNIP3 Kv channel interacting protein 3, calsenilin
KIAA0368 KIAA0368
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPEPPS aminopeptidase puromycin sensitive
NUP205 nucleoporin 205kDa
NUP93 nucleoporin 93kDa
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RIF1 replication timing regulatory factor 1
RPN1 ribophorin I
RPN2 ribophorin II
SAMM50 SAMM50 sorting and assembly machinery component
SBDS Shwachman-Bodian-Diamond syndrome
SCAMP3 secretory carrier membrane protein 3
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFXN1 sideroflexin 1
SFXN3 sideroflexin 3
SFXN4 sideroflexin 4
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SSR4 signal sequence receptor, delta
STRA6 stimulated by retinoic acid 6
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TECR trans-2,3-enoyl-CoA reductase
TELO2 telomere maintenance 2
TFRC transferrin receptor
TMEM33 transmembrane protein 33
TMPO thymopoietin
TRIP13 thyroid hormone receptor interactor 13
UBC ubiquitin C
UNC45A unc-45 homolog A (C. elegans)
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VDAC2 voltage-dependent anion channel 2
XPO1 exportin 1
XPO5 exportin 5
XPOT exportin, tRNA