CLPP_KO_GDS4791_537_mouse_testis Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation]_[GEO accession]_[perturbation ID]_[organism]_[cell or tissue] (Gene Expression Omnibus)
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441 genes differentially expressed following the CLPP_KO_GDS4791_537_mouse_testis gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABHD2 abhydrolase domain containing 2
ACRV1 acrosomal vesicle protein 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL7A actin-like 7A
ACTL9 actin-like 9
ACTRT2 actin-related protein T2
ACVR1C activin A receptor, type IC
ADAM21 ADAM metallopeptidase domain 21
ADAM7 ADAM metallopeptidase domain 7
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AIF1 allograft inflammatory factor 1
AKAP3 A kinase (PRKA) anchor protein 3
AKAP4 A kinase (PRKA) anchor protein 4
ALLC allantoicase
ANGPTL1 angiopoietin-like 1
ANKRD35 ankyrin repeat domain 35
ANKRD45 ankyrin repeat domain 45
ANKRD61 ankyrin repeat domain 61
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
ARMC12 armadillo repeat containing 12
ARR3 arrestin 3, retinal (X-arrestin)
ARRDC5 arrestin domain containing 5
ASB17 ankyrin repeat and SOCS box containing 17
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
BANF2 barrier to autointegration factor 2
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BPIFA3 BPI fold containing family A, member 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BSND barttin CLCNK-type chloride channel accessory beta subunit
CABS1 calcium-binding protein, spermatid-specific 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALB1 calbindin 1, 28kDa
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CARTPT CART prepropeptide
CATSPER1 cation channel, sperm associated 1
CATSPER3 cation channel, sperm associated 3
CCDC159 coiled-coil domain containing 159
CCDC63 coiled-coil domain containing 63
CCDC67 coiled-coil domain containing 67
CCDC70 coiled-coil domain containing 70
CCDC81 coiled-coil domain containing 81
CCDC85A coiled-coil domain containing 85A
CCER1 coiled-coil glutamate-rich protein 1
CCRL2 chemokine (C-C motif) receptor-like 2
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD180 CD180 molecule
CD96 CD96 molecule
CDC123 cell division cycle 123
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDRT4 CMT1A duplicated region transcript 4
CEP295NL CEP295 N-terminal like
CFHR1 complement factor H-related 1
CHGA chromogranin A
CIB4 calcium and integrin binding family member 4
CLDN6 claudin 6
CLDND2 claudin domain containing 2
CLEC4C C-type lectin domain family 4, member C
CLIC6 chloride intracellular channel 6
CNPY1 canopy FGF signaling regulator 1
COL20A1 collagen, type XX, alpha 1
COL22A1 collagen, type XXII, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CPOX coproporphyrinogen oxidase
CREB3L4 cAMP responsive element binding protein 3-like 4
CSNK1D casein kinase 1, delta
CTNNA3 catenin (cadherin-associated protein), alpha 3
CUZD1 CUB and zona pellucida-like domains 1
DCLK1 doublecortin-like kinase 1
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DGKK diacylglycerol kinase, kappa
DLX1 distal-less homeobox 1
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DPYSL3 dihydropyrimidinase-like 3
DQX1 DEAQ box RNA-dependent ATPase 1
DUSP13 dual specificity phosphatase 13
DYDC2 DPY30 domain containing 2
EFCAB6 EF-hand calcium binding domain 6
EFCAB9 EF-hand calcium binding domain 9
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF3H eukaryotic translation initiation factor 3, subunit H
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENO2 enolase 2 (gamma, neuronal)
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
FAM110A family with sequence similarity 110, member A
FAM166A family with sequence similarity 166, member A
FAM170B family with sequence similarity 170, member B
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
FAM209B family with sequence similarity 209, member B
FAM217A family with sequence similarity 217, member A
FAM221B family with sequence similarity 221, member B
FAM227A family with sequence similarity 227, member A
FAM229A family with sequence similarity 229, member A
FAM3B family with sequence similarity 3, member B
FAM71A family with sequence similarity 71, member A
FAM71B family with sequence similarity 71, member B
FAM71E1 family with sequence similarity 71, member E1
FAM71F1 family with sequence similarity 71, member F1
FANCD2OS FANCD2 opposite strand
FHDC1 FH2 domain containing 1
FHL3 four and a half LIM domains 3
FHL5 four and a half LIM domains 5
FPR1 formyl peptide receptor 1
FSCN3 fascin actin-bundling protein 3, testicular
FTMT ferritin mitochondrial
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
FZD9 frizzled class receptor 9
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GFAP glial fibrillary acidic protein
GJA10 gap junction protein, alpha 10, 62kDa
GJB4 gap junction protein, beta 4, 30.3kDa
GLYAT glycine-N-acyltransferase
GPSM3 G-protein signaling modulator 3
GPX5 glutathione peroxidase 5
GPX6 glutathione peroxidase 6
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSG1 germ cell associated 1
HAS3 hyaluronan synthase 3
HDAC11 histone deacetylase 11
HK1 hexokinase 1
HMGB4 high mobility group box 4
HOOK1 hook microtubule-tethering protein 1
HOXA2 homeobox A2
HSPA1L heat shock 70kDa protein 1-like
ICA1 islet cell autoantigen 1, 69kDa
IFI16 interferon, gamma-inducible protein 16
IL10 interleukin 10
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
INA internexin neuronal intermediate filament protein, alpha
IQCF1 IQ motif containing F1
IQCF5 IQ motif containing F5
IQSEC2 IQ motif and Sec7 domain 2
IRGC immunity-related GTPase family, cinema
ISG20 interferon stimulated exonuclease gene 20kDa
IZUMO1 izumo sperm-egg fusion 1
IZUMO3 IZUMO family member 3
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCTD16 potassium channel tetramerization domain containing 16
KIF17 kinesin family member 17
KIF2B kinesin family member 2B
KLF3 Kruppel-like factor 3 (basic)
KLHL10 kelch-like family member 10
KRT26 keratin 26, type I
LCN8 lipocalin 8
LHX9 LIM homeobox 9
LIPE lipase, hormone-sensitive
LIPN lipase, family member N
LKAAEAR1 LKAAEAR motif containing 1
LOC100505478 uncharacterized LOC100505478
LOC100505841 zinc finger protein 474-like
LOC101929469 uncharacterized protein ENSP00000372125
LOC102723899 uncharacterized LOC102723899
LOC285423 uncharacterized LOC285423
LOC728392 uncharacterized LOC728392
LOC730159 uncharacterized LOC730159
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRRC18 leucine rich repeat containing 18
LRRC69 leucine rich repeat containing 69
LRRIQ4 leucine-rich repeats and IQ motif containing 4
LYPD8 LY6/PLAUR domain containing 8
LYRM7 LYR motif containing 7
LYZL1 lysozyme-like 1
LYZL4 lysozyme-like 4
MAP2 microtubule-associated protein 2
MBD3L1 methyl-CpG binding domain protein 3-like 1
MCTP2 multiple C2 domains, transmembrane 2
MICALCL MICAL C-terminal like
MIPOL1 mirror-image polydactyly 1
MMEL1 membrane metallo-endopeptidase-like 1
MORN3 MORN repeat containing 3
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCR1 natural cytotoxicity triggering receptor 1
NIPAL4 NIPA-like domain containing 4
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOXRED1 NADP-dependent oxidoreductase domain containing 1
NPC2 Niemann-Pick disease, type C2
NT5C1B 5'-nucleotidase, cytosolic IB
ODF1 outer dense fiber of sperm tails 1
ODF3 outer dense fiber of sperm tails 3
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR6A2 olfactory receptor, family 6, subfamily A, member 2
PABPC4L poly(A) binding protein, cytoplasmic 4-like
PAQR9 progestin and adipoQ receptor family member IX
PCDHB11 protocadherin beta 11
PDILT protein disulfide isomerase-like, testis expressed
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PFN3 profilin 3
PGK2 phosphoglycerate kinase 2
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLA2G10 phospholipase A2, group X
PLA2G12B phospholipase A2, group XIIB
PMFBP1 polyamine modulated factor 1 binding protein 1
PNLIP pancreatic lipase
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J
PPP1R32 protein phosphatase 1, regulatory subunit 32
PRDM14 PR domain containing 14
PRKCQ protein kinase C, theta
PRM3 protamine 3
PROCA1 protein interacting with cyclin A1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRR12 proline rich 12
PRR22 proline rich 22
PRSS46 protease, serine, 46
PRSS54 protease, serine, 54
PRSS55 protease, serine, 55
PTHLH parathyroid hormone-like hormone
PTRH2 peptidyl-tRNA hydrolase 2
PWWP2B PWWP domain containing 2B
PYGO2 pygopus family PHD finger 2
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF133 ring finger protein 133
RNF151 ring finger protein 151
ROPN1 rhophilin associated tail protein 1
SAXO1 stabilizer of axonemal microtubules 1
SCP2D1 SCP2 sterol-binding domain containing 1
SELV selenoprotein V
SFRP1 secreted frizzled-related protein 1
SIRPB1 signal-regulatory protein beta 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC16A4 solute carrier family 16, member 4
SLC22A14 solute carrier family 22, member 14
SLC35G6 solute carrier family 35, member G6
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC51A solute carrier family 51, alpha subunit
SLFNL1 schlafen-like 1
SMIM23 small integral membrane protein 23
SOD2 superoxide dismutase 2, mitochondrial
SPACA4 sperm acrosome associated 4
SPACA7 sperm acrosome associated 7
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPATA19 spermatogenesis associated 19
SPATA21 spermatogenesis associated 21
SPATA25 spermatogenesis associated 25
SPATA3 spermatogenesis associated 3
SPATC1 spermatogenesis and centriole associated 1
SPATC1L spermatogenesis and centriole associated 1-like
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPEM1 spermatid maturation 1
SPERT spermatid associated
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPZ1 spermatogenic leucine zipper 1
SREBF2 sterol regulatory element binding transcription factor 2
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT4 signal transducer and activator of transcription 4
STX3 syntaxin 3
SUN5 Sad1 and UNC84 domain containing 5
SUSD5 sushi domain containing 5
SYNC syncoilin, intermediate filament protein
SYT6 synaptotagmin VI
TAC3 tachykinin 3
TBC1D21 TBC1 domain family, member 21
TEPP testis, prostate and placenta expressed
TEX13A testis expressed 13A
TEX14 testis expressed 14
TEX22 testis expressed 22
TEX33 testis expressed 33
TEX35 testis expressed 35
TEX36 testis expressed 36
TEX37 testis expressed 37
TEX38 testis expressed 38
TEX43 testis expressed 43
TGM5 transglutaminase 5
THEG theg spermatid protein
THSD4 thrombospondin, type I, domain containing 4
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMC5 transmembrane channel-like 5
TMEM210 transmembrane protein 210
TMEM225 transmembrane protein 225
TMEM231 transmembrane protein 231
TMEM247 transmembrane protein 247
TMEM53 transmembrane protein 53
TMPRSS15 transmembrane protease, serine 15
TMPRSS4 transmembrane protease, serine 4
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TP53TG5 TP53 target 5
TPRG1 tumor protein p63 regulated 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM42 tripartite motif containing 42
TRIML1 tripartite motif family-like 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSGA13 testis specific, 13
TSKS testis-specific serine kinase substrate
TSPAN2 tetraspanin 2
TSSK1B testis-specific serine kinase 1B
TSSK2 testis-specific serine kinase 2
TSSK6 testis-specific serine kinase 6
TTC39A tetratricopeptide repeat domain 39A
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
TYRP1 tyrosinase-related protein 1
UBL4B ubiquitin-like 4B
UBQLN3 ubiquilin 3
UBQLNL ubiquilin-like
UPK3BL uroplakin 3B-like
USP50 ubiquitin specific peptidase 50
VIL1 villin 1
VIPR1 vasoactive intestinal peptide receptor 1
VSIG2 V-set and immunoglobulin domain containing 2
VWA3A von Willebrand factor A domain containing 3A
WBP2NL WBP2 N-terminal like
WBSCR28 Williams-Beuren syndrome chromosome region 28
WDR18 WD repeat domain 18
WDR64 WD repeat domain 64
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZAN zonadhesin (gene/pseudogene)
ZBTB49 zinc finger and BTB domain containing 49
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC17 zinc finger, DHHC-type containing 17
ZDHHC19 zinc finger, DHHC-type containing 19
ZIK1 zinc finger protein interacting with K protein 1
ZMYND15 zinc finger, MYND-type containing 15
ZNF474 zinc finger protein 474
ZNF580 zinc finger protein 580
ZNRF4 zinc and ring finger 4
ZYG11A zyg-11 family member A, cell cycle regulator

decreased expression

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
AMDHD1 amidohydrolase domain containing 1
ANGPTL7 angiopoietin-like 7
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
AURKAIP1 aurora kinase A interacting protein 1
BFSP2 beaded filament structural protein 2, phakinin
CCDC125 coiled-coil domain containing 125
CD19 CD19 molecule
CDX1 caudal type homeobox 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CROT carnitine O-octanoyltransferase
DEPDC5 DEP domain containing 5
DHRS7 dehydrogenase/reductase (SDR family) member 7
DKK2 dickkopf WNT signaling pathway inhibitor 2
DMGDH dimethylglycine dehydrogenase
DOCK5 dedicator of cytokinesis 5
DPT dermatopontin
DRAM1 DNA-damage regulated autophagy modulator 1
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
ESRRG estrogen-related receptor gamma
FAM101B family with sequence similarity 101, member B
FAM216B family with sequence similarity 216, member B
FAM72A family with sequence similarity 72, member A
FGD3 FYVE, RhoGEF and PH domain containing 3
FOXA2 forkhead box A2
GIMAP6 GTPase, IMAP family member 6
GLRA3 glycine receptor, alpha 3
GPR1 G protein-coupled receptor 1
GPR158 G protein-coupled receptor 158
GPR26 G protein-coupled receptor 26
IER5 immediate early response 5
IL7 interleukin 7
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL28 kelch-like family member 28
KLK11 kallikrein-related peptidase 11
KRT6B keratin 6B, type II
LAX1 lymphocyte transmembrane adaptor 1
LEPR leptin receptor
LONRF2 LON peptidase N-terminal domain and ring finger 2
LRP3 low density lipoprotein receptor-related protein 3
LRRC38 leucine rich repeat containing 38
LZTS2 leucine zipper, putative tumor suppressor 2
MAB21L3 mab-21-like 3 (C. elegans)
MACC1 metastasis associated in colon cancer 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MIOX myo-inositol oxygenase
MMRN1 multimerin 1
MYCT1 myc target 1
MYOT myotilin
NIPAL1 NIPA-like domain containing 1
NPNT nephronectin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OLAH oleoyl-ACP hydrolase
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDH18 protocadherin 18
PCDHB7 protocadherin beta 7
PDAP1 PDGFA associated protein 1
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PPP1R17 protein phosphatase 1, regulatory subunit 17
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTAFR platelet-activating factor receptor
PTBP1 polypyrimidine tract binding protein 1
RAD17 RAD17 homolog (S. pombe)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RET ret proto-oncogene
RGS7BP regulator of G-protein signaling 7 binding protein
RNF183 ring finger protein 183
RNF219 ring finger protein 219
RRM2 ribonucleotide reductase M2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCN3B sodium channel, voltage gated, type III beta subunit
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SFMBT1 Scm-like with four mbt domains 1
SFRP2 secreted frizzled-related protein 2
SHISA6 shisa family member 6
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SMAD9 SMAD family member 9
SMCO3 single-pass membrane protein with coiled-coil domains 3
SOCS2 suppressor of cytokine signaling 2
SSTR2 somatostatin receptor 2
ST7 suppression of tumorigenicity 7
TBC1D30 TBC1 domain family, member 30
TBX15 T-box 15
TFPI2 tissue factor pathway inhibitor 2
THEMIS2 thymocyte selection associated family member 2
TLL1 tolloid-like 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
ULBP1 UL16 binding protein 1
VSTM2B V-set and transmembrane domain containing 2B
WNT16 wingless-type MMTV integration site family, member 16
ZNF546 zinc finger protein 546
ZNF689 zinc finger protein 689