CNP Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description 2',3'-cyclic nucleotide 3' phosphodiesterase| (NCBI Entrez Gene Database, 1267)
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Genes

282 genes differentially expressed following the CNP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CYSLTR1 cysteinyl leukotriene receptor 1 2.61209
UPK3B uroplakin 3B 2.61209
F2 coagulation factor II (thrombin) 2.61209
MLN motilin 2.61209
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.61209
GOLGA7B golgin A7 family, member B 2.61209
C2CD4A C2 calcium-dependent domain containing 4A 2.61209
RXFP2 relaxin/insulin-like family peptide receptor 2 2.61209
TULP2 tubby like protein 2 2.61209
LIX1 Lix1 homolog (chicken) 2.61209
ESR1 estrogen receptor 1 2.61209
THSD8 thrombospondin type 1 domain containing 8 2.61209
NOTCH2NLB notch 2 N-terminal like B 2.61209
CD38 CD38 molecule 2.61209
STRC stereocilin 2.61209
MEIOSIN meiosis initiator 2.61209
SKOR2 SKI family transcriptional corepressor 2 2.5626
SOX9 SRY (sex determining region Y)-box 9 2.5626
ARMCX1 armadillo repeat containing, X-linked 1 2.5626
SAV1 salvador family WW domain containing protein 1 2.53423
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.53423
PNPLA1 patatin-like phospholipase domain containing 1 2.53423
TMEM217 transmembrane protein 217 2.53423
OCSTAMP osteoclast stimulatory transmembrane protein 2.53423
HNF1A HNF1 homeobox A 2.53423
PSCA prostate stem cell antigen 2.53423
NDP Norrie disease (pseudoglioma) 2.53423
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.53423
RAX2 retina and anterior neural fold homeobox 2 2.53423
PITX2 paired-like homeodomain 2 2.53423
HOXB3 homeobox B3 2.53423
FGF6 fibroblast growth factor 6 2.53423
FGF3 fibroblast growth factor 3 2.53423
PMCH pro-melanin-concentrating hormone 2.53423
MGAT4D MGAT4 family, member D 2.53423
SPACA7 sperm acrosome associated 7 2.53423
RD3 retinal degeneration 3 2.53423
CLEC14A C-type lectin domain family 14, member A 2.53423
AVP arginine vasopressin 2.53423
CRYGB crystallin, gamma B 2.53423
MUC22 mucin 22 2.53423
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.53423
OR2D3 olfactory receptor, family 2, subfamily D, member 3 2.53423
ZNF503 zinc finger protein 503 2.53423
ASB15 ankyrin repeat and SOCS box containing 15 2.53423
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.53423
FOXD1 forkhead box D1 2.53423
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.53423
OR5P2 olfactory receptor, family 5, subfamily P, member 2 2.53423
FPR1 formyl peptide receptor 1 2.53423
SPDYE6 speedy/RINGO cell cycle regulator family member E6 2.53423
OR51B4 olfactory receptor, family 51, subfamily B, member 4 2.53423
VSX2 visual system homeobox 2 2.53423
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.53423
MTNR1B melatonin receptor 1B 2.53423
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.53423
GPR52 G protein-coupled receptor 52 2.53423
MYOM2 myomesin 2 2.53423
GYPB glycophorin B (MNS blood group) 2.53423
PGLYRP2 peptidoglycan recognition protein 2 2.53423
MTMR9 myotubularin related protein 9 2.53423
TMEM191B transmembrane protein 191B 2.53423
SIM2 single-minded family bHLH transcription factor 2 2.53423
PCDHGB3 protocadherin gamma subfamily B, 3 2.53423
TCHH trichohyalin 2.53423
ZNF467 zinc finger protein 467 2.53423
CATSPER3 cation channel, sperm associated 3 2.53423
FABP1 fatty acid binding protein 1, liver 2.53423
SCGB3A1 secretoglobin, family 3A, member 1 2.53423
PAX2 paired box 2 2.53423
BHLHA15 basic helix-loop-helix family, member a15 2.53423
HBG2 hemoglobin, gamma G 2.53423
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.53423
FBXO47 F-box protein 47 2.53423
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.53423
CER1 cerberus 1, DAN family BMP antagonist 2.53423
VWA3B von Willebrand factor A domain containing 3B 2.53423
MUC13 mucin 13, cell surface associated 2.53423
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.53423
KLF2 Kruppel-like factor 2 2.53423
PTPRH protein tyrosine phosphatase, receptor type, H 2.53423
CCN6 cellular communication network factor 6 2.53423
AQP7 aquaporin 7 2.53423
FYB1 FYN binding protein 1 2.53423
CLXN calaxin 2.53423
UTS2R urotensin 2 receptor 2.53423
CHIT1 chitinase 1 (chitotriosidase) 2.53423
WNT1 wingless-type MMTV integration site family, member 1 2.53423
DENND2C DENN/MADD domain containing 2C 2.53423
CALHM4 calcium homeostasis modulator family member 4 2.53423
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.53423
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.53423
FAIM2 Fas apoptotic inhibitory molecule 2 2.53423
SMIM31 small integral membrane protein 31 2.53423
TUBB8B tubulin beta 8B 2.53423
DNAAF6 dynein axonemal assembly factor 6 2.53423
NCR3 natural cytotoxicity triggering receptor 3 2.53423
NOBOX NOBOX oogenesis homeobox 2.53423
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.53423
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.53423
ZC3H10 zinc finger CCCH-type containing 10 2.53423
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.53423
RNF224 ring finger protein 224 2.53423
RERGL RERG/RAS-like 2.53423
ITPKA inositol-trisphosphate 3-kinase A 2.53423
SNTN sentan, cilia apical structure protein 2.53423
MCHR1 melanin-concentrating hormone receptor 1 2.53423
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 2.53423
TEX36 testis expressed 36 2.53423
TGM6 transglutaminase 6 2.53423
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.53423
IL37 interleukin 37 2.53423
LGI1 leucine-rich, glioma inactivated 1 2.53423
GPR179 G protein-coupled receptor 179 2.53423
ZNF407 zinc finger protein 407 2.53423
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.53423
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.53423
GBP2 guanylate binding protein 2, interferon-inducible 2.53423
SPATS1 spermatogenesis associated, serine-rich 1 2.53423
CCL24 chemokine (C-C motif) ligand 24 2.53423
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.53423
APOH apolipoprotein H (beta-2-glycoprotein I) 2.53423
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.53423
KRT15 keratin 15, type I 2.53423
SFTPA1 surfactant protein A1 2.53423
PRND prion protein 2 (dublet) 2.53423
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 2.53423
RUFY4 RUN and FYVE domain containing 4 2.53423
B4GAT1 beta-1,4-glucuronyltransferase 1 2.53423
TBC1D21 TBC1 domain family, member 21 2.53423
MT4 metallothionein 4 2.53423
LTB4R2 leukotriene B4 receptor 2 2.53423
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.4575
EPHA3 EPH receptor A3 2.4575
SYMPK symplekin 2.42424
TM9SF2 transmembrane 9 superfamily member 2 2.4217
ZCCHC24 zinc finger, CCHC domain containing 24 2.41606
FMN1 formin 1 2.41263
AARS1 alanyl-tRNA synthetase 1 2.39544
ZNF776 zinc finger protein 776 2.34869
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 2.33014
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.32727
TF transferrin 2.32727
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.32727
TMC2 transmembrane channel-like 2 2.30146
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.27109
GRPR gastrin-releasing peptide receptor 2.26842
GATA3 GATA binding protein 3 2.25618
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 2.25584
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 2.24408
UPK3A uroplakin 3A 2.23524
ZNF493 zinc finger protein 493 2.22476
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.21973
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 2.21398
CDX4 caudal type homeobox 4 2.2121
LONRF2 LON peptidase N-terminal domain and ring finger 2 2.20512
SELENOW selenoprotein W 2.16695
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 2.16695
GPAT4 glycerol-3-phosphate acyltransferase 4 2.15911
FAM53C family with sequence similarity 53, member C 2.13394
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.12152
PPP6R1 protein phosphatase 6, regulatory subunit 1 2.10581
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 2.09267
DGLUCY D-glutamate cyclase 2.09267
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 2.09267
DNALI1 dynein, axonemal, light intermediate chain 1 2.09225
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 2.09225
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.07148
CIAO2B cytosolic iron-sulfur assembly component 2B 2.06438
IFT43 intraflagellar transport 43 2.05961
DLG1 discs, large homolog 1 (Drosophila) 2.04998
CIC capicua transcriptional repressor 2.04548
ANKRD44 ankyrin repeat domain 44 2.01477
TCHP trichoplein, keratin filament binding 2.01215
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.00427
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.00324
GNA12 guanine nucleotide binding protein (G protein) alpha 12 2.00324

decreased expression

Symbol Name Standardized Value
LMX1B LIM homeobox transcription factor 1, beta -2.61209
H4C6 H4 clustered histone 6 -2.61209
NR1I2 nuclear receptor subfamily 1, group I, member 2 -2.61209
KCNK13 potassium channel, two pore domain subfamily K, member 13 -2.61209
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.61209
CCNA1 cyclin A1 -2.61209
EVPL envoplakin -2.61209
RIT1 Ras-like without CAAX 1 -2.61209
FGF4 fibroblast growth factor 4 -2.61209
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -2.61209
CLC Charcot-Leyden crystal galectin -2.53423
DNM1L dynamin 1-like -2.53423
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.53423
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -2.53423
GGN gametogenetin -2.53423
RSPO3 R-spondin 3 -2.53423
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -2.53423
TDRD5 tudor domain containing 5 -2.53423
NFU1 NFU1 iron-sulfur cluster scaffold -2.53423
FOXG1 forkhead box G1 -2.53423
NCKAP1 NCK-associated protein 1 -2.53423
KIF18B kinesin family member 18B -2.53423
PRR22 proline rich 22 -2.53423
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -2.53423
IGFBP7 insulin-like growth factor binding protein 7 -2.53423
RBBP7 retinoblastoma binding protein 7 -2.53423
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -2.53423
PRR4 proline rich 4 (lacrimal) -2.53423
TM4SF19 transmembrane 4 L six family member 19 -2.53423
PEAK3 PEAK family member 3 -2.53423
LRRN4 leucine rich repeat neuronal 4 -2.53423
PCDH11X protocadherin 11 X-linked -2.53423
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -2.53423
ZFTRAF1 zinc finger TRAF-type containing 1 -2.53423
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -2.53423
CXCL16 chemokine (C-X-C motif) ligand 16 -2.53423
KLHL41 kelch-like family member 41 -2.53423
CTXN2 cortexin 2 -2.53423
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.53423
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.53423
C3ORF80 chromosome 3 open reading frame 80 -2.53423
PADI3 peptidyl arginine deiminase, type III -2.48461
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.45803
TET2 tet methylcytosine dioxygenase 2 -2.4562
CCDC158 coiled-coil domain containing 158 -2.44251
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -2.44251
PCDH10 protocadherin 10 -2.42969
RBM20 RNA binding motif protein 20 -2.41606
TNMD tenomodulin -2.41606
UFSP1 UFM1-specific peptidase 1 (non-functional) -2.41606
OR56A3 olfactory receptor, family 56, subfamily A, member 3 -2.41606
KCTD19 potassium channel tetramerization domain containing 19 -2.39112
NRIP2 nuclear receptor interacting protein 2 -2.37415
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -2.28768
LAMC2 laminin, gamma 2 -2.28768
TMEM14A transmembrane protein 14A -2.28768
ACIN1 apoptotic chromatin condensation inducer 1 -2.26278
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -2.24705
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -2.24186
NFIL3 nuclear factor, interleukin 3 regulated -2.24134
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.22353
SHOC1 shortage in chiasmata 1 -2.20169
DIABLO diablo, IAP-binding mitochondrial protein -2.16762
FGFR2 fibroblast growth factor receptor 2 -2.15885
ADORA1 adenosine A1 receptor -2.15885
ZBTB35 zinc finger and BTB domain containing 35 -2.15885
ZSCAN20 zinc finger and SCAN domain containing 20 -2.15885
RBM14 RNA binding motif protein 14 -2.15254
TMEM265 transmembrane protein 265 -2.13394
ELF2 E74-like factor 2 (ets domain transcription factor) -2.13394
RHOV ras homolog family member V -2.11618
INO80C INO80 complex subunit C -2.11618
GAGE10 G antigen 10 -2.11618
HORMAD2 HORMA domain containing 2 -2.11618
BAIAP3 BAI1-associated protein 3 -2.11618
EPSTI1 epithelial stromal interaction 1 (breast) -2.09267
CKS1B CDC28 protein kinase regulatory subunit 1B -2.09267
FKBP8 FK506 binding protein 8, 38kDa -2.09267
TTLL9 tubulin tyrosine ligase-like family member 9 -2.09267
SCP2 sterol carrier protein 2 -2.09267
ACACB acetyl-CoA carboxylase beta -2.09225
SOCS5 suppressor of cytokine signaling 5 -2.09225
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -2.09225
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.09225
CCDC134 coiled-coil domain containing 134 -2.09225
TMEM147 transmembrane protein 147 -2.09225
DISP1 dispatched homolog 1 (Drosophila) -2.09225
AIF1L allograft inflammatory factor 1-like -2.09225
ZNF304 zinc finger protein 304 -2.08232
APOOL apolipoprotein O-like -2.06736
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -2.06736
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.06736
ZNF572 zinc finger protein 572 -2.06736
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -2.06438
CCDC88B coiled-coil domain containing 88B -2.05778
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.04998
SYNPR synaptoporin -2.04998
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.04998
TDG thymine-DNA glycosylase -2.04998
ZNF430 zinc finger protein 430 -2.03166
MRPS18A mitochondrial ribosomal protein S18A -2.02857
PSMC3IP PSMC3 interacting protein -2.02614
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 -2.01411
ZNF573 zinc finger protein 573 -2.01411
IFI27L2 interferon, alpha-inducible protein 27-like 2 -2.01215