COCAINE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca. (Chemical Entities of Biological Interest Ontology, CHEBI_27958)
External Link https://dgidb.org/results?searchType=drug&searchTerms=COCAINE
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Genes

12 interacting proteins for the COCAINE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.401
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.284581
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.279177
SCN11A sodium channel, voltage gated, type XI alpha subunit 0.133667
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.112144
SCN10A sodium channel, voltage gated, type X alpha subunit 0.096945
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.093851
SCN5A sodium channel, voltage gated, type V alpha subunit 0.0832264
DRD3 dopamine receptor D3 0.0754017
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 0.0723115
OPRK1 opioid receptor, kappa 1 0.0673435
DRD1 dopamine receptor D1 0.0242363