| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | collagen, type IV, alpha 3 (Goodpasture antigen)|Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 1285) |
| External Link | https://ncbi.nlm.nih.gov/gene/1285 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the COL4A3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | 0.0169712 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0152428 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0128835 |
| NTS | neurotensin | 0.0114684 |
| NMU | neuromedin U | 0.0112679 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.011192 |
| PRDX2 | peroxiredoxin 2 | 0.0111414 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0111102 |
| NRN1 | neuritin 1 | 0.0109693 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.0107799 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0107299 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0106296 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0104412 |
| OIP5 | Opa interacting protein 5 | 0.0103552 |
| CNN3 | calponin 3, acidic | 0.0103344 |
| HBB | hemoglobin, beta | 0.0103115 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0102919 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0102391 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0102178 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00998502 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00984424 |
| CLU | clusterin | 0.00976481 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00955831 |
| CHKB | choline kinase beta | 0.00955822 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00955776 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00950854 |
| KIF20A | kinesin family member 20A | 0.00947261 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00944792 |
| DHFR | dihydrofolate reductase | 0.00943871 |
| RPA3 | replication protein A3, 14kDa | 0.00935875 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00923162 |
| LMNB1 | lamin B1 | 0.00921304 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00915097 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00909538 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00900601 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0089516 |
| CA9 | carbonic anhydrase IX | 0.00893431 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00890806 |
| HPF1 | histone PARylation factor 1 | 0.00890409 |
| LBR | lamin B receptor | 0.0088829 |
| FASN | fatty acid synthase | 0.00887932 |
| CCNA2 | cyclin A2 | 0.00884944 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00880714 |
| TMSB15A | thymosin beta 15a | 0.00879032 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00877194 |
| KIF18B | kinesin family member 18B | 0.00871108 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00868582 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00859865 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00857379 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00855734 |
| RAPSN | receptor-associated protein of the synapse | 0.00851147 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00850597 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00848195 |
| TMEM38B | transmembrane protein 38B | 0.00840912 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00840428 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00839536 |
| BRCA1 | breast cancer 1, early onset | 0.00837375 |
| MGAM | maltase-glucoamylase | 0.00834579 |
| TMEM14B | transmembrane protein 14B | 0.00831451 |
| LRRC17 | leucine rich repeat containing 17 | 0.00830345 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00828512 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00828181 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00826397 |
| PLPBP | pyridoxal phosphate binding protein | 0.00822921 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00822397 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00820699 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00820294 |
| RHOB | ras homolog family member B | 0.00817435 |
| NEK2 | NIMA-related kinase 2 | 0.00816417 |
| OLFM4 | olfactomedin 4 | 0.00809913 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00807297 |
| LTA4H | leukotriene A4 hydrolase | 0.00806431 |
| HDDC2 | HD domain containing 2 | 0.00805016 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00803592 |
| TMEM106C | transmembrane protein 106C | 0.00803277 |
| SRP9 | signal recognition particle 9kDa | 0.00800456 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00799165 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0079355 |
| ACO1 | aconitase 1, soluble | 0.00793156 |
| KIF4A | kinesin family member 4A | 0.00792481 |
| WASHC4 | WASH complex subunit 4 | 0.00783327 |
| LTF | lactotransferrin | 0.00782466 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00779878 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00778683 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00774246 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00772091 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00771266 |
| HP | haptoglobin | 0.00771111 |
| CST3 | cystatin C | 0.00766763 |
| RPS5 | ribosomal protein S5 | 0.00760312 |
| TSNAX | translin-associated factor X | 0.00758604 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.0075426 |
| FABP1 | fatty acid binding protein 1, liver | 0.0075416 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00752587 |
| AURKB | aurora kinase B | 0.00752271 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00751244 |
| IL7R | interleukin 7 receptor | 0.00747352 |
| C1R | complement component 1, r subcomponent | 0.00746932 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00745639 |
| RANBP1 | RAN binding protein 1 | 0.00744407 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00743491 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00742678 |
| KLHDC3 | kelch domain containing 3 | 0.00741933 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00740216 |
| EREG | epiregulin | 0.00737916 |
| B3GNT1 | 0.00736986 | |
| FAM162A | family with sequence similarity 162, member A | 0.00736373 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.0073535 |
| CST7 | cystatin F (leukocystatin) | 0.0073524 |
| PITX1 | paired-like homeodomain 1 | 0.00734627 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00733407 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00729785 |
| KIF11 | kinesin family member 11 | 0.00729716 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00729053 |
| GLO1 | glyoxalase I | 0.0072807 |
| KRT13 | keratin 13, type I | 0.00725851 |
| CCNF | cyclin F | 0.00724483 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.00723847 |
| TRMT5 | tRNA methyltransferase 5 | 0.00723826 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.0072381 |
| CEP70 | centrosomal protein 70kDa | 0.00721627 |
| CLC | Charcot-Leyden crystal galectin | 0.00718047 |
| RXRA | retinoid X receptor, alpha | 0.00715955 |
| SELL | selectin L | 0.00714784 |
| TMEM14A | transmembrane protein 14A | 0.00714145 |
| DUT | deoxyuridine triphosphatase | 0.00711759 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00711754 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00711687 |
| WDR7 | WD repeat domain 7 | 0.00711542 |
| THYN1 | thymocyte nuclear protein 1 | 0.00711274 |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.00710998 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00709995 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00709677 |
| INSIG1 | insulin induced gene 1 | 0.00709104 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00707257 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00707158 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.007053 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00702827 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00702229 |
| NUP37 | nucleoporin 37kDa | 0.00701765 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00698844 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00697653 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00697315 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00693804 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00691183 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00689699 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00689391 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00689102 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.006882 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.00687567 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00686065 |
| AUTS2 | autism susceptibility candidate 2 | 0.00685826 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00682318 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00681787 |
| CFI | complement factor I | 0.00678421 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00677932 |
| CDCA3 | cell division cycle associated 3 | 0.00677882 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00676259 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00674326 |
| COPS4 | COP9 signalosome subunit 4 | 0.00674046 |
| NDC80 | NDC80 kinetochore complex component | 0.00672346 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00672255 |
| COMMD10 | COMM domain containing 10 | 0.00668587 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00668309 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00665822 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00665249 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00664492 |
| PLBD1 | phospholipase B domain containing 1 | 0.00664315 |
| QDPR | quinoid dihydropteridine reductase | 0.00662477 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00659862 |
| LIN28A | lin-28 homolog A (C. elegans) | 0.00655812 |
| NANOG | Nanog homeobox | 0.00655525 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.006543 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00653746 |
| ABHD10 | abhydrolase domain containing 10 | 0.00653665 |
| CDK1 | cyclin-dependent kinase 1 | 0.00653577 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00651728 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00650873 |
| PLK1 | polo-like kinase 1 | 0.00650797 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00650345 |
| EXTL2 | exostosin-like glycosyltransferase 2 | 0.00649986 |
| FOXM1 | forkhead box M1 | 0.00649153 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00647981 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00647133 |
| TROAP | trophinin associated protein | 0.00646354 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00644249 |
| CLIC3 | chloride intracellular channel 3 | 0.00644151 |
| E2F8 | E2F transcription factor 8 | 0.00643057 |
| DDHD2 | DDHD domain containing 2 | 0.00638845 |
| PIMREG | PICALM interacting mitotic regulator | 0.00636268 |
| AURKA | aurora kinase A | 0.00636232 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00635239 |
| SELENBP1 | selenium binding protein 1 | 0.00634016 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.0063396 |
| PCP4 | Purkinje cell protein 4 | 0.00630724 |
| APMAP | adipocyte plasma membrane associated protein | 0.00630199 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 0.00630047 |
| TMEM106B | transmembrane protein 106B | 0.00629957 |
| CD2 | CD2 molecule | 0.00629074 |
| FBXO5 | F-box protein 5 | 0.00628744 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0062868 |
| TYRO3 | TYRO3 protein tyrosine kinase | 0.00628203 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00626232 |
| CD320 | CD320 molecule | 0.00624632 |
| PTCH1 | patched 1 | 0.00623913 |
| SET | SET nuclear proto-oncogene | 0.00623255 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00622883 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00622244 |
| CASC3 | cancer susceptibility candidate 3 | 0.00621387 |
| COL1A2 | collagen, type I, alpha 2 | 0.00620918 |
| TK1 | thymidine kinase 1, soluble | 0.00619968 |
| FLOT2 | flotillin 2 | 0.00619897 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00618818 |
| LMNB2 | lamin B2 | 0.00616557 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00616026 |
| RNF130 | ring finger protein 130 | 0.00614674 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00614515 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.00614144 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00613493 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00613201 |
| DEK | DEK proto-oncogene | 0.0061132 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00609571 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00608386 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00607243 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | 0.00606546 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00605762 |
| SLC2A4RG | SLC2A4 regulator | 0.00604124 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00604001 |
| RPA2 | replication protein A2, 32kDa | 0.00602721 |
| UBE2N | ubiquitin-conjugating enzyme E2N | 0.00602677 |
| GCHFR | GTP cyclohydrolase I feedback regulator | 0.00602343 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00602029 |
| MRPS27 | mitochondrial ribosomal protein S27 | 0.00601669 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00601018 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00600307 |
| C21ORF33 | chromosome 21 open reading frame 33 | 0.00598738 |
| GLB1 | galactosidase, beta 1 | 0.00595222 |
| NELL2 | NEL-like 2 (chicken) | 0.00595131 |
| CDC6 | cell division cycle 6 | 0.00595088 |
| PLP1 | proteolipid protein 1 | 0.00594591 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00593837 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00593102 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 0.00592763 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00591885 |
| MRTFB | myocardin related transcription factor B | 0.00590328 |
| BTBD2 | BTB (POZ) domain containing 2 | 0.00588907 |
| DEPDC1 | DEP domain containing 1 | 0.00588408 |
| PARK7 | parkinson protein 7 | 0.00588079 |
| USP1 | ubiquitin specific peptidase 1 | 0.00586739 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00585991 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MX1 | MX dynamin-like GTPase 1 | -0.0228426 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0209385 |
| IFI44L | interferon-induced protein 44-like | -0.0196081 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0187108 |
| COG7 | component of oligomeric golgi complex 7 | -0.0185466 |
| KRT14 | keratin 14, type I | -0.0179687 |
| PROM1 | prominin 1 | -0.0175997 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0173286 |
| KRT7 | keratin 7, type II | -0.0164827 |
| HMOX1 | heme oxygenase 1 | -0.0159523 |
| KRT17 | keratin 17, type I | -0.0159047 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0155628 |
| ASS1 | argininosuccinate synthase 1 | -0.0153229 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0148775 |
| CCN2 | cellular communication network factor 2 | -0.0147436 |
| APOD | apolipoprotein D | -0.0145018 |
| IER5 | immediate early response 5 | -0.0144322 |
| LAMC2 | laminin, gamma 2 | -0.0136446 |
| TRIM29 | tripartite motif containing 29 | -0.0132269 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0131075 |
| INHBA | inhibin, beta A | -0.012933 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0128444 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0127562 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0125916 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0125006 |
| JMJD1C | jumonji domain containing 1C | -0.0123928 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0121625 |
| MVP | major vault protein | -0.0121595 |
| HSPA2 | heat shock 70kDa protein 2 | -0.0121531 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0120957 |
| MMP7 | matrix metallopeptidase 7 | -0.0120269 |
| IFI44 | interferon-induced protein 44 | -0.011973 |
| MFAP5 | microfibrillar associated protein 5 | -0.0119353 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0119073 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0118119 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0117191 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0116376 |
| TPBG | trophoblast glycoprotein | -0.0115522 |
| DUSP5 | dual specificity phosphatase 5 | -0.0114833 |
| KLF6 | Kruppel-like factor 6 | -0.0113727 |
| SIK1 | salt-inducible kinase 1 | -0.0112482 |
| MGLL | monoglyceride lipase | -0.0112016 |
| IRF9 | interferon regulatory factor 9 | -0.0111962 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.0111495 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.010913 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.0108262 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.010818 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.010792 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0107913 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0107517 |
| LAMB3 | laminin, beta 3 | -0.010741 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.010676 |
| CRYAB | crystallin, alpha B | -0.0105922 |
| MSMB | microseminoprotein, beta- | -0.0105736 |
| EGR2 | early growth response 2 | -0.0104801 |
| MYO1B | myosin IB | -0.01045 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.0104442 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0103396 |
| KRT23 | keratin 23, type I | -0.0102157 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0101782 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.0101122 |
| MMP10 | matrix metallopeptidase 10 | -0.0100685 |
| KYNU | kynureninase | -0.0100193 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00999422 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00995712 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00975449 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00974655 |
| MAP7 | microtubule-associated protein 7 | -0.00971341 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00968267 |
| GAS1 | growth arrest-specific 1 | -0.00967585 |
| AHR | aryl hydrocarbon receptor | -0.00966833 |
| MYBPC1 | myosin binding protein C, slow type | -0.00964525 |
| TRIM22 | tripartite motif containing 22 | -0.00955384 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00954843 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00953738 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00952934 |
| RGCC | regulator of cell cycle | -0.00949839 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00948296 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0094732 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00945501 |
| STK26 | serine/threonine protein kinase 26 | -0.00944595 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00942629 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00937832 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00937616 |
| KLHL24 | kelch-like family member 24 | -0.00933629 |
| IRF7 | interferon regulatory factor 7 | -0.00926799 |
| ZNF706 | zinc finger protein 706 | -0.00925658 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00924571 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00924555 |
| YBX3 | Y box binding protein 3 | -0.00922103 |
| TFF1 | trefoil factor 1 | -0.00920877 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00919636 |
| OXTR | oxytocin receptor | -0.00917106 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00909972 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00909858 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00907953 |
| TOX3 | TOX high mobility group box family member 3 | -0.00903606 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00903374 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00896963 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00895053 |
| CCNG2 | cyclin G2 | -0.00892753 |
| PLAU | plasminogen activator, urokinase | -0.00887269 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00880409 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00878998 |
| MIR22HG | MIR22 host gene | -0.00878518 |
| SP100 | SP100 nuclear antigen | -0.00876477 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00876459 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00876057 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0087319 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00869561 |
| PERP | PERP, TP53 apoptosis effector | -0.00865816 |
| PRNP | prion protein | -0.00865125 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00864555 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00864142 |
| ATF3 | activating transcription factor 3 | -0.00859169 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00858247 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00855072 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00854149 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00853788 |
| TSPAN1 | tetraspanin 1 | -0.00853679 |
| MCL1 | myeloid cell leukemia 1 | -0.00853372 |
| PIP | prolactin-induced protein | -0.00853106 |
| INAVA | innate immunity activator | -0.00851156 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00848129 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00845507 |
| KRT81 | keratin 81, type II | -0.0084109 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00838917 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00838529 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00836122 |
| XAF1 | XIAP associated factor 1 | -0.0083223 |
| BSDC1 | BSD domain containing 1 | -0.0083144 |
| GSN | gelsolin | -0.00830037 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00829518 |
| PTHLH | parathyroid hormone-like hormone | -0.00828103 |
| RRAGC | Ras-related GTP binding C | -0.00825876 |
| DUSP10 | dual specificity phosphatase 10 | -0.00820723 |
| CHGB | chromogranin B | -0.00818043 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00815756 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00815363 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00815186 |
| CPM | carboxypeptidase M | -0.00813751 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00809432 |
| BEX4 | brain expressed, X-linked 4 | -0.00808509 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00807406 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00805587 |
| FHL2 | four and a half LIM domains 2 | -0.00805492 |
| GAS6 | growth arrest-specific 6 | -0.00803735 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00801414 |
| RET | ret proto-oncogene | -0.0079776 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00795605 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00795571 |
| KRT5 | keratin 5, type II | -0.00792051 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.00789577 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00785882 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00784707 |
| FRMD4B | FERM domain containing 4B | -0.00783554 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00781434 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00780813 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0077526 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00771953 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00771223 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00770946 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00768009 |
| SQSTM1 | sequestosome 1 | -0.00767243 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00766069 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00763622 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00763438 |
| GOLGA8H | golgin A8 family, member H | -0.00763293 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0076325 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00760946 |
| NOTCH2NL | notch 2 N-terminal like | -0.00760602 |
| LAMA2 | laminin, alpha 2 | -0.00757747 |
| AHNAK | AHNAK nucleoprotein | -0.00753276 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00752711 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00750031 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.007492 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0074911 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00746751 |
| JAK1 | Janus kinase 1 | -0.00746126 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00743267 |
| PLLP | plasmolipin | -0.00741752 |
| MUC16 | mucin 16, cell surface associated | -0.00741329 |
| BTG2 | BTG family, member 2 | -0.00738079 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00737837 |
| MX2 | MX dynamin-like GTPase 2 | -0.00736112 |
| SPAG9 | sperm associated antigen 9 | -0.00736012 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00735452 |
| SYNM | synemin, intermediate filament protein | -0.00732587 |
| ZNF83 | zinc finger protein 83 | -0.00732323 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00730771 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00730644 |
| OGA | O-GlcNAcase | -0.00728696 |
| TUFT1 | tuftelin 1 | -0.0072831 |
| RRAD | Ras-related associated with diabetes | -0.00726529 |
| MYRF | myelin regulatory factor | -0.00724935 |
| OAT | ornithine aminotransferase | -0.00722332 |
| LIMK2 | LIM domain kinase 2 | -0.00720945 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00720887 |
| SGCE | sarcoglycan, epsilon | -0.00719657 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00718419 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00716351 |
| RSRP1 | arginine/serine-rich protein 1 | -0.00715943 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00714222 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | -0.00712792 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00712626 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00710688 |
| SPAG1 | sperm associated antigen 1 | -0.00710594 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00710451 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00708718 |
| TXLNA | taxilin alpha | -0.00707644 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00707252 |
| HOMER1 | homer scaffolding protein 1 | -0.00705012 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00703179 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -0.0070313 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00702319 |
| DEFB1 | defensin, beta 1 | -0.00700625 |
| EGR1 | early growth response 1 | -0.00699866 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00698486 |
| PTN | pleiotrophin | -0.00697984 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00697716 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00695912 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00695798 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.00694722 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.00693482 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00692763 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00692463 |
| IL6 | interleukin 6 | -0.00692334 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00690433 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00688594 |
| KLK11 | kallikrein-related peptidase 11 | -0.00687404 |
| FN1 | fibronectin 1 | -0.00686661 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00685744 |
| DUSP4 | dual specificity phosphatase 4 | -0.00683671 |
| PLPP2 | phospholipid phosphatase 2 | -0.00683248 |
| PLK3 | polo-like kinase 3 | -0.00682828 |
| CTSL | cathepsin L | -0.00682522 |
| RYBP | RING1 and YY1 binding protein | -0.0068158 |
| KLK5 | kallikrein-related peptidase 5 | -0.00679616 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00679554 |
| POSTN | periostin, osteoblast specific factor | -0.00679109 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00678673 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00678553 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00677868 |
| OGFRL1 | opioid growth factor receptor-like 1 | -0.00673467 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00672604 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00672252 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00670191 |
| TGFA | transforming growth factor, alpha | -0.00668379 |
| NDE1 | nudE neurodevelopment protein 1 | -0.00667581 |
| CAVIN3 | caveolae associated protein 3 | -0.00667143 |
