COLO-680N Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, squamous cell (Cell Line Ontology, CLO_0002573)
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Genes

258 genes with high or low expression in COLO-680N relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ALPP alkaline phosphatase, placental 2.6252
RNPEP arginyl aminopeptidase (aminopeptidase B) 2.53181
GMPS guanine monphosphate synthase 2.39347
CAPN1 calpain 1, (mu/I) large subunit 2.3291
TRIM17 tripartite motif containing 17 2.30176
RHOBTB3 Rho-related BTB domain containing 3 2.29124
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.16761
CEP57 centrosomal protein 57kDa 1.99883
DIO2 deiodinase, iodothyronine, type II 1.9732
RBL2 retinoblastoma-like 2 1.9475
USF2 upstream transcription factor 2, c-fos interacting 1.94397
ADAMTSL4 ADAMTS-like 4 1.93507
KRT8P12 keratin 8 pseudogene 12 1.89658
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.88748
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 1.87059
TIMP2 TIMP metallopeptidase inhibitor 2 1.86009
BANF1 barrier to autointegration factor 1 1.85728
SIPA1 signal-induced proliferation-associated 1 1.83595
HFE hemochromatosis 1.81268
ZDHHC24 zinc finger, DHHC-type containing 24 1.79926
MRPL11 mitochondrial ribosomal protein L11 1.78993
ITCH itchy E3 ubiquitin protein ligase 1.7366
WFDC2 WAP four-disulfide core domain 2 1.73171
MARCO macrophage receptor with collagenous structure 1.73009
MMRN2 multimerin 2 1.72377
CHD8 chromodomain helicase DNA binding protein 8 1.71111
PLA2G16 phospholipase A2, group XVI 1.70719
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.69442
KDM1A lysine (K)-specific demethylase 1A 1.69231
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.68826
KIF3B kinesin family member 3B 1.65488
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.64971
BCL7C B-cell CLL/lymphoma 7C 1.63294
FAM65A family with sequence similarity 65, member A 1.62528
TP53 tumor protein p53 1.57553
ATXN3 ataxin 3 1.57146
ALPPL2 alkaline phosphatase, placental-like 2 1.56502
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1.55852
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 1.55757
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.55476
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.55148
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.53231
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.53126
GABARAPL1 GABA(A) receptor-associated protein like 1 1.53076
MUC16 mucin 16, cell surface associated 1.52983
EHD1 EH-domain containing 1 1.52293
MMP12 matrix metallopeptidase 12 1.52271
NABP1 nucleic acid binding protein 1 1.51829
THSD4 thrombospondin, type I, domain containing 4 1.51611
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.51505
SASH1 SAM and SH3 domain containing 1 1.51041
PRPF8 pre-mRNA processing factor 8 1.49822
URGCP upregulator of cell proliferation 1.4981
LTBP3 latent transforming growth factor beta binding protein 3 1.49657
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 1.49569
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.49308
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.49117
TEAD3 TEA domain family member 3 1.48826
SERTAD3 SERTA domain containing 3 1.48181
TSKU tsukushi, small leucine rich proteoglycan 1.4747
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.47329
ITGB4 integrin, beta 4 1.45691
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.45622
KDM2A lysine (K)-specific demethylase 2A 1.45338
CLMN calmin (calponin-like, transmembrane) 1.45102
DPP3 dipeptidyl-peptidase 3 1.44575
UPK1A uroplakin 1A 1.44451
SRCAP Snf2-related CREBBP activator protein 1.44432
BCKDK branched chain ketoacid dehydrogenase kinase 1.4435
CHKA choline kinase alpha 1.4338
ZNF204P zinc finger protein 204, pseudogene 1.4326
CIB2 calcium and integrin binding family member 2 1.42949
RAB1B RAB1B, member RAS oncogene family 1.42911
RLN2 relaxin 2 1.42236
PCDH7 protocadherin 7 1.42162

low expression

Symbol Name Standardized Value
SETMAR SET domain and mariner transposase fusion gene -3.53725
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -3.0802
ZNF253 zinc finger protein 253 -3.07865
EXOG endo/exonuclease (5'-3'), endonuclease G-like -3.06044
MBD2 methyl-CpG binding domain protein 2 -3.02857
PARP8 poly (ADP-ribose) polymerase family, member 8 -2.98555
AGTPBP1 ATP/GTP binding protein 1 -2.93868
YTHDC2 YTH domain containing 2 -2.83974
POLI polymerase (DNA directed) iota -2.81847
RBMS3 RNA binding motif, single stranded interacting protein 3 -2.68774
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -2.66475
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.59545
TRAPPC10 trafficking protein particle complex 10 -2.51024
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.41329
PCNT pericentrin -2.40587
RRP1B ribosomal RNA processing 1B -2.39541
ZCCHC10 zinc finger, CCHC domain containing 10 -2.37869
TAS2R4 taste receptor, type 2, member 4 -2.33124
PKNOX1 PBX/knotted 1 homeobox 1 -2.32963
SETD4 SET domain containing 4 -2.32839
HINT1 histidine triad nucleotide binding protein 1 -2.30815
CA5BP1 carbonic anhydrase VB pseudogene 1 -2.30736
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) -2.27618
AK5 adenylate kinase 5 -2.26264
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -2.26099
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -2.25878
GSTM5 glutathione S-transferase mu 5 -2.22344
YY2 YY2 transcription factor -2.22335
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -2.22146
DCLRE1A DNA cross-link repair 1A -2.22118
RPA4 replication protein A4, 30kDa -2.21493
GLRA1 glycine receptor, alpha 1 -2.16535
PRMT2 protein arginine methyltransferase 2 -2.14892
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.14296
RBPJ recombination signal binding protein for immunoglobulin kappa J region -2.14007
CDRT1 CMT1A duplicated region transcript 1 -2.12903
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -2.11453
APC adenomatous polyposis coli -2.09663
DMRT1 doublesex and mab-3 related transcription factor 1 -2.09207
NARS asparaginyl-tRNA synthetase -2.06606
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 -2.04069
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -2.03381
ADAM22 ADAM metallopeptidase domain 22 -2.02879
FEM1C fem-1 homolog c (C. elegans) -2.02778
NEUROD1 neuronal differentiation 1 -2.00819
SMAD2 SMAD family member 2 -2.00599
TLL2 tolloid-like 2 -1.99059
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.97424
HMP19 HMP19 protein -1.94795
ELAVL4 ELAV like neuron-specific RNA binding protein 4 -1.9428
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -1.93861
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.92281
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -1.92081
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.91974
RIOK2 RIO kinase 2 -1.89873
MCM3AP minichromosome maintenance complex component 3 associated protein -1.89328
SKP1 S-phase kinase-associated protein 1 -1.89257
ATG12 autophagy related 12 -1.88841
PARG poly (ADP-ribose) glycohydrolase -1.88577
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -1.86708
ZNF250 zinc finger protein 250 -1.85731
LMAN1 lectin, mannose-binding, 1 -1.85346
PQLC1 PQ loop repeat containing 1 -1.85338
BCL2L10 BCL2-like 10 (apoptosis facilitator) -1.85122
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.84612
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -1.82525
CCL25 chemokine (C-C motif) ligand 25 -1.82338
CFHR2 complement factor H-related 2 -1.82276
ERBB4 erb-b2 receptor tyrosine kinase 4 -1.82275
TAS2R14 taste receptor, type 2, member 14 -1.81858
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -1.80649
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -1.80296
DAPK3 death-associated protein kinase 3 -1.80228
NHEJ1 nonhomologous end-joining factor 1 -1.79546
ZNF24 zinc finger protein 24 -1.79104
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -1.78448
IFNA4 interferon, alpha 4 -1.7633
PRELP proline/arginine-rich end leucine-rich repeat protein -1.76226
GPRASP1 G protein-coupled receptor associated sorting protein 1 -1.76063
GORASP1 golgi reassembly stacking protein 1, 65kDa -1.75732
SNX2 sorting nexin 2 -1.75547
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.74941
KRT38 keratin 38, type I -1.74936
RHOBTB1 Rho-related BTB domain containing 1 -1.74703
DMXL1 Dmx-like 1 -1.74576
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -1.73991
HIST1H2AJ histone cluster 1, H2aj -1.73265
RBBP8 retinoblastoma binding protein 8 -1.73023
ATP8B4 ATPase, class I, type 8B, member 4 -1.72678
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -1.72656
INSL4 insulin-like 4 (placenta) -1.7147
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -1.70972
RNF144A ring finger protein 144A -1.70621
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -1.69384
TAS2R13 taste receptor, type 2, member 13 -1.68786
ANO2 anoctamin 2, calcium activated chloride channel -1.68185
PRKY protein kinase, Y-linked, pseudogene -1.67953
EIF1AX eukaryotic translation initiation factor 1A, X-linked -1.67901
DNASE1L3 deoxyribonuclease I-like 3 -1.67867
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -1.67464
DCP2 decapping mRNA 2 -1.67416
ZNF208 zinc finger protein 208 -1.66753
CA5B carbonic anhydrase VB, mitochondrial -1.66655
RYR2 ryanodine receptor 2 (cardiac) -1.66171
SDS serine dehydratase -1.64458
COMMD3 COMM domain containing 3 -1.64241
PLCH1 phospholipase C, eta 1 -1.63951
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -1.62853
TRDMT1 tRNA aspartic acid methyltransferase 1 -1.62195
CDC37 cell division cycle 37 -1.61966
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -1.61795
SRP19 signal recognition particle 19kDa -1.61794
ISOC1 isochorismatase domain containing 1 -1.61657
AVIL advillin -1.61645
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.61485
CAPN11 calpain 11 -1.61022
TMEM165 transmembrane protein 165 -1.60191
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.59413
ASPHD1 aspartate beta-hydroxylase domain containing 1 -1.59235
TTC3 tetratricopeptide repeat domain 3 -1.58386
TRPM6 transient receptor potential cation channel, subfamily M, member 6 -1.58218
MRPL34 mitochondrial ribosomal protein L34 -1.57581
COL2A1 collagen, type II, alpha 1 -1.57095
CRTAC1 cartilage acidic protein 1 -1.56563
HSPA4 heat shock 70kDa protein 4 -1.56313
DOCK2 dedicator of cytokinesis 2 -1.56165
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -1.5548
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.55337
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -1.55124
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.5482
CD1B CD1b molecule -1.54733
MYOG myogenin (myogenic factor 4) -1.54602
LOC51145 uncharacterized LOC51145 -1.54152
DCHS1 dachsous cadherin-related 1 -1.53672
ZFP2 ZFP2 zinc finger protein -1.5361
ZNF767P zinc finger family member 767, pseudogene -1.5342
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -1.53052
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -1.52404
SH3GL3 SH3-domain GRB2-like 3 -1.52345
PAX8 paired box 8 -1.5217
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -1.51904
PIAS2 protein inhibitor of activated STAT, 2 -1.51872
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -1.51616
CSNK1G3 casein kinase 1, gamma 3 -1.51561
CCL27 chemokine (C-C motif) ligand 27 -1.51206
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.51018
TPM3 tropomyosin 3 -1.50964
RP2 retinitis pigmentosa 2 (X-linked recessive) -1.50356
AUTS2 autism susceptibility candidate 2 -1.50329
KRT9 keratin 9, type I -1.50067
CREM cAMP responsive element modulator -1.50046
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -1.50042
MBD1 methyl-CpG binding domain protein 1 -1.49804
LOC157562 uncharacterized LOC157562 -1.49781
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -1.49625
CYSLTR1 cysteinyl leukotriene receptor 1 -1.49479
MRPL20 mitochondrial ribosomal protein L20 -1.49425
LTK leukocyte receptor tyrosine kinase -1.48923
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.48767
LRRC6 leucine rich repeat containing 6 -1.48292
AFF4 AF4/FMR2 family, member 4 -1.47391
SLC25A38 solute carrier family 25, member 38 -1.47389
SPON2 spondin 2, extracellular matrix protein -1.46718
GPR27 G protein-coupled receptor 27 -1.46616
MPPED1 metallophosphoesterase domain containing 1 -1.46423
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -1.46099
DSCR3 Down syndrome critical region 3 -1.45977
SEC31B SEC31 homolog B (S. cerevisiae) -1.45886
ASIC2 acid sensing (proton gated) ion channel 2 -1.4581
OXSR1 oxidative stress responsive 1 -1.45452
MAGEA4 melanoma antigen family A4 -1.45426
GPC3 glypican 3 -1.45031
U2AF1 U2 small nuclear RNA auxiliary factor 1 -1.44829
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -1.44286
FCGBP Fc fragment of IgG binding protein -1.44252
OR2F2 olfactory receptor, family 2, subfamily F, member 2 -1.44067
PHF8 PHD finger protein 8 -1.44
GK glycerol kinase -1.43796
PCDHB3 protocadherin beta 3 -1.43765
GPR63 G protein-coupled receptor 63 -1.43737
NPY5R neuropeptide Y receptor Y5 -1.43418
TRHDE thyrotropin-releasing hormone degrading enzyme -1.43135
HCRTR2 hypocretin (orexin) receptor 2 -1.41858