COLO205 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

521 gene knockdowns changing fitness of COLO205 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
UBE2R2 ubiquitin-conjugating enzyme E2R 2 3.19303
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 3.19064
SOCS4 suppressor of cytokine signaling 4 3.11823
NRIP1 nuclear receptor interacting protein 1 3.11588
IL12A interleukin 12A 3.01502
HRASLS HRAS-like suppressor 2.99036
CLASP1 cytoplasmic linker associated protein 1 2.94936
SRSF4 serine/arginine-rich splicing factor 4 2.43342
ZNF773 zinc finger protein 773 2.4009
TUBB tubulin, beta class I 2.2829
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.28077
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.27129
ELAC1 elaC ribonuclease Z 1 2.20142
NPEPPS aminopeptidase puromycin sensitive 2.17943
SIX6 SIX homeobox 6 2.17342
XBP1 X-box binding protein 1 2.16023
OCM oncomodulin 2.1444
EXOSC8 exosome component 8 2.11551
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.02411
ZNF514 zinc finger protein 514 2.01992
GIPR gastric inhibitory polypeptide receptor 1.99915
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 1.97454
RBM47 RNA binding motif protein 47 1.96713
TAS2R5 taste receptor, type 2, member 5 1.95887
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.95714
ZNF138 zinc finger protein 138 1.95179
SNAPIN SNAP-associated protein 1.93712
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.93612
TLE3 transducin-like enhancer of split 3 1.91016
MORF4L1 mortality factor 4 like 1 1.89948
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.86187
CLEC4D C-type lectin domain family 4, member D 1.85884
ACAT1 acetyl-CoA acetyltransferase 1 1.85457
BCHE butyrylcholinesterase 1.83079
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 1.82808
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 1.82628
MPO myeloperoxidase 1.8214
TUBB4B tubulin, beta 4B class IVb 1.80488
NGF nerve growth factor (beta polypeptide) 1.78681
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.78407
LPP LIM domain containing preferred translocation partner in lipoma 1.75811
BCR breakpoint cluster region 1.75319
CDO1 cysteine dioxygenase type 1 1.74995
CLSTN2 calsyntenin 2 1.74719
CNGA3 cyclic nucleotide gated channel alpha 3 1.74477
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 1.7247
BTK Bruton agammaglobulinemia tyrosine kinase 1.71727
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.71716
EMX2 empty spiracles homeobox 2 1.71426
NEK1 NIMA-related kinase 1 1.70743
NRGN neurogranin (protein kinase C substrate, RC3) 1.7019
TMF1 TATA element modulatory factor 1 1.6994
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) 1.69081
SPINK1 serine peptidase inhibitor, Kazal type 1 1.66889
EMX1 empty spiracles homeobox 1 1.66532
OGFR opioid growth factor receptor 1.66234
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.65207
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 1.64928
DCLK3 doublecortin-like kinase 3 1.64575
ZNF423 zinc finger protein 423 1.63939
GPR183 G protein-coupled receptor 183 1.6248
BCL2 B-cell CLL/lymphoma 2 1.61544
PTDSS2 phosphatidylserine synthase 2 1.61185
VRK3 vaccinia related kinase 3 1.6104
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.60758
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.60656
RANBP9 RAN binding protein 9 1.58227
PRPF38B pre-mRNA processing factor 38B 1.57794
KIF16B kinesin family member 16B 1.57369
USPL1 ubiquitin specific peptidase like 1 1.57269
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 1.56851
NSF N-ethylmaleimide-sensitive factor 1.5618
TIPE2 TNF alpha induced protein 8 like 2 1.56155
ICOS inducible T-cell co-stimulator 1.55075
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.5486
ZNF257 zinc finger protein 257 1.54118
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.535
ZFP36L1 ZFP36 ring finger protein-like 1 1.53194
TAS2R1 taste receptor, type 2, member 1 1.53036
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.52918
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.51096
ZNF681 zinc finger protein 681 1.50756
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.50578
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough 1.49237
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.49208
ALG1L ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 1.49077
TUBGCP3 tubulin, gamma complex associated protein 3 1.48287
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 1.47649
EGFL6 EGF-like-domain, multiple 6 1.46956
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.46752
MTA3 metastasis associated 1 family, member 3 1.46438
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 1.45855
USP9X ubiquitin specific peptidase 9, X-linked 1.45191
SAE1 SUMO1 activating enzyme subunit 1 1.44945
PM20D1 peptidase M20 domain containing 1 1.44909
MTL5 metallothionein-like 5, testis-specific (tesmin) 1.44834
ZNF728 zinc finger protein 728 1.44549
LDHA lactate dehydrogenase A 1.44355
AHCYL2 adenosylhomocysteinase-like 2 1.43595
ADAM22 ADAM metallopeptidase domain 22 1.43419
DCT dopachrome tautomerase 1.42956
OR7A5 olfactory receptor, family 7, subfamily A, member 5 1.42461
PPAP2A phosphatidic acid phosphatase type 2A 1.42441
ZNF600 zinc finger protein 600 1.41885
SCN1A sodium channel, voltage gated, type I alpha subunit 1.41862
IL22 interleukin 22 1.41758
UBQLNL ubiquilin-like 1.40853
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.40758
HIST1H3A histone cluster 1, H3a 1.40708
FOXK1 forkhead box K1 1.3996
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 1.39884
SNRPA small nuclear ribonucleoprotein polypeptide A 1.3901
SULF1 sulfatase 1 1.38683
GPR160 G protein-coupled receptor 160 1.38358
AVIL advillin 1.38339
GSC goosecoid homeobox 1.38174
ZNF729 zinc finger protein 729 1.3804
JMJD1C jumonji domain containing 1C 1.37125
NOP16 NOP16 nucleolar protein 1.37081
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 1.36736
MUC7 mucin 7, secreted 1.36558
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 1.35814
EIF6 eukaryotic translation initiation factor 6 1.35624
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.35564
CD274 CD274 molecule 1.35316
KIAA0430 KIAA0430 1.35155
OR51T1 olfactory receptor, family 51, subfamily T, member 1 1.35093
ZBTB17 zinc finger and BTB domain containing 17 1.34919
ZNF79 zinc finger protein 79 1.34548
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.34531
IFNA2 interferon, alpha 2 1.33388
TRIB3 tribbles pseudokinase 3 1.33309
PLXNB1 plexin B1 1.31358
ZNF222 zinc finger protein 222 1.31356
CDH20 cadherin 20, type 2 1.309
ALDOA aldolase A, fructose-bisphosphate 1.30301
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.30097
PGAM1 phosphoglycerate mutase 1 (brain) 1.29435
PRKCE protein kinase C, epsilon 1.29424
PAPOLG poly(A) polymerase gamma 1.29208
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.29023
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 1.28729
OR52W1 olfactory receptor, family 52, subfamily W, member 1 1.28727
PBK PDZ binding kinase 1.28479
ERBB3 erb-b2 receptor tyrosine kinase 3 1.27942
ZBTB40 zinc finger and BTB domain containing 40 1.27854
DCST1 DC-STAMP domain containing 1 1.27395
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.26817
EFCAB2 EF-hand calcium binding domain 2 1.26722
KCMF1 potassium channel modulatory factor 1 1.2623
ANXA4 annexin A4 1.26204
EDA ectodysplasin A 1.26014
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.25817
IGF1 insulin-like growth factor 1 (somatomedin C) 1.24933
TRA2A transformer 2 alpha homolog (Drosophila) 1.24851
PSAT1 phosphoserine aminotransferase 1 1.24037
COX7C cytochrome c oxidase subunit VIIc 1.23599
KRTAP5-2 keratin associated protein 5-2 1.22911
INHBC inhibin, beta C 1.2289
SIN3B SIN3 transcription regulator family member B 1.22648
TOM1 target of myb1 (chicken) 1.22546
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.21602
LEPROT leptin receptor overlapping transcript 1.20771
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 1.20146
OAZ1 ornithine decarboxylase antizyme 1 1.19892
TARBP1 TAR (HIV-1) RNA binding protein 1 1.19832
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 1.19602
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.19535
CLEC2D C-type lectin domain family 2, member D 1.19191
RNF144A ring finger protein 144A 1.18924
AHCTF1 AT hook containing transcription factor 1 1.18888
TRPV5 transient receptor potential cation channel, subfamily V, member 5 1.18474
CRYAA crystallin, alpha A 1.18202
ELF5 E74-like factor 5 (ets domain transcription factor) 1.17676
WNT1 wingless-type MMTV integration site family, member 1 1.17658
PLA2G4B phospholipase A2, group IVB (cytosolic) 1.16978
GAB1 GRB2-associated binding protein 1 1.16964
FBXW2 F-box and WD repeat domain containing 2 1.16832
DTNB dystrobrevin, beta 1.15762
ZNF568 zinc finger protein 568 1.15737
POC1A POC1 centriolar protein A 1.15724
IL2RB interleukin 2 receptor, beta 1.15419
ZNF407 zinc finger protein 407 1.15401
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.1523
ZNF560 zinc finger protein 560 1.14773
CREG1 cellular repressor of E1A-stimulated genes 1 1.14515
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.13663
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.13436
FGF17 fibroblast growth factor 17 1.13189
ZBTB22 zinc finger and BTB domain containing 22 1.11544
INPP5F inositol polyphosphate-5-phosphatase F 1.11261
METAP1 methionyl aminopeptidase 1 1.11033
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 1.10811
ZMYM1 zinc finger, MYM-type 1 1.10759
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.10525
BRCA1 breast cancer 1, early onset 1.10197
LCK LCK proto-oncogene, Src family tyrosine kinase 1.10044
ZNF737 zinc finger protein 737 1.09893
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.09651
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.095
CDK4 cyclin-dependent kinase 4 1.09492
COX7B2 cytochrome c oxidase subunit VIIb2 1.09457
EGFL7 EGF-like-domain, multiple 7 1.09449
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.09003
TRIP4 thyroid hormone receptor interactor 4 1.08871
NUPL1 nucleoporin like 1 1.08675
STK32A serine/threonine kinase 32A 1.08439
PRDX1 peroxiredoxin 1 1.08117
TIGD6 tigger transposable element derived 6 1.08116
G6PC2 glucose-6-phosphatase, catalytic, 2 1.07815
GYS2 glycogen synthase 2 (liver) 1.07556
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.0727
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 1.07222
DBNL drebrin-like 1.06192
POLL polymerase (DNA directed), lambda 1.06152
VN1R5 vomeronasal 1 receptor 5 (gene/pseudogene) 1.06098
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.05993
NUCB1 nucleobindin 1 1.05986
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 1.0597
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.0495
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.04732
SMAD4 SMAD family member 4 1.03937
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.0362
PCDHA2 protocadherin alpha 2 1.03473
HIATL1 hippocampus abundant transcript-like 1 1.03454
FRK fyn-related Src family tyrosine kinase 1.03428
FFAR2 free fatty acid receptor 2 1.03376
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.03276
GOLGA4 golgin A4 1.03037
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 1.02712
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 1.02115
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.02103
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.01835
DTX3L deltex 3 like, E3 ubiquitin ligase 1.01729
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.01446
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 1.0143
ABR active BCR-related 1.01269
H1FOO H1 histone family, member O, oocyte-specific 1.01256
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 1.00838
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.00706
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1.00331
OCRL oculocerebrorenal syndrome of Lowe 1.00265
ZNF154 zinc finger protein 154 1.00049

decreased fitness

Symbol Name Standardized Value
PRSS55 protease, serine, 55 -3.15868
TRIM62 tripartite motif containing 62 -3.09726
PPP6C protein phosphatase 6, catalytic subunit -2.99864
BRAF B-Raf proto-oncogene, serine/threonine kinase -2.85252
ARF4 ADP-ribosylation factor 4 -2.71547
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.57156
OIT3 oncoprotein induced transcript 3 -2.56523
CCND3 cyclin D3 -2.55123
ZNF81 zinc finger protein 81 -2.51278
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.47136
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.45257
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 -2.42445
FBXO27 F-box protein 27 -2.38789
ATF6 activating transcription factor 6 -2.37045
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.36916
CDX4 caudal type homeobox 4 -2.36256
IRF1 interferon regulatory factor 1 -2.30149
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.29717
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -2.28197
OR5AU1 olfactory receptor, family 5, subfamily AU, member 1 -2.19706
CD248 CD248 molecule, endosialin -2.1939
BLOC1S1-RDH5 BLOC1S1-RDH5 readthrough -2.16113
CPB1 carboxypeptidase B1 (tissue) -2.15771
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.15321
ATXN7 ataxin 7 -2.07233
MYLK3 myosin light chain kinase 3 -2.06175
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.05835
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -2.05327
GATA6 GATA binding protein 6 -2.04541
C17ORF75 chromosome 17 open reading frame 75 -2.03004
ZNF322 zinc finger protein 322 -1.94499
USP20 ubiquitin specific peptidase 20 -1.89835
TMOD1 tropomodulin 1 -1.89323
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 -1.86099
DGKQ diacylglycerol kinase, theta 110kDa -1.85976
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -1.84952
OTUD7B OTU deubiquitinase 7B -1.84151
DDIT4 DNA-damage-inducible transcript 4 -1.82781
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -1.80425
CD36 CD36 molecule (thrombospondin receptor) -1.80275
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 -1.80089
NPR2 natriuretic peptide receptor 2 -1.77628
ZNF573 zinc finger protein 573 -1.75946
NHLH2 nescient helix loop helix 2 -1.75848
LYRM7 LYR motif containing 7 -1.74242
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.73746
KLF5 Kruppel-like factor 5 (intestinal) -1.71621
AFP alpha-fetoprotein -1.71161
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -1.71074
NF1 neurofibromin 1 -1.6934
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.68513
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -1.67973
ZNF775 zinc finger protein 775 -1.67341
CALML5 calmodulin-like 5 -1.66646
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.6663
APC adenomatous polyposis coli -1.66499
NUMBL numb homolog (Drosophila)-like -1.66222
NOX4 NADPH oxidase 4 -1.64983
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -1.62491
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -1.62422
WNK3 WNK lysine deficient protein kinase 3 -1.62355
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.60865
BMP7 bone morphogenetic protein 7 -1.58854
SOD3 superoxide dismutase 3, extracellular -1.58395
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -1.58311
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 -1.57787
CDK6 cyclin-dependent kinase 6 -1.57641
GZMM granzyme M (lymphocyte met-ase 1) -1.57327
LAPTM4A lysosomal protein transmembrane 4 alpha -1.56734
ZNF484 zinc finger protein 484 -1.56673
HARS histidyl-tRNA synthetase -1.56636
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -1.55305
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -1.53505
MMP24 matrix metallopeptidase 24 (membrane-inserted) -1.53415
MPPE1 metallophosphoesterase 1 -1.52969
EIF2D eukaryotic translation initiation factor 2D -1.50187
PFN4 profilin family, member 4 -1.49839
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -1.49753
IRS2 insulin receptor substrate 2 -1.48103
TBC1D25 TBC1 domain family, member 25 -1.47542
MGAT4C MGAT4 family, member C -1.47268
ZNF835 zinc finger protein 835 -1.46983
LEFTY2 left-right determination factor 2 -1.46738
USP17L3 ubiquitin specific peptidase 17-like family member 3 -1.46301
BMP8A bone morphogenetic protein 8a -1.46075
PHACTR4 phosphatase and actin regulator 4 -1.45789
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.45413
USP17L4 ubiquitin specific peptidase 17-like family member 4 -1.45323
TRIM33 tripartite motif containing 33 -1.44732
PIAS4 protein inhibitor of activated STAT, 4 -1.44518
MTMR12 myotubularin related protein 12 -1.44378
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.43122
CFLAR CASP8 and FADD-like apoptosis regulator -1.41229
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.41121
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 -1.40948
POMC proopiomelanocortin -1.40868
OR1S1 olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene) -1.4
USP17L5 ubiquitin specific peptidase 17-like family member 5 -1.39572
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -1.39161
POU4F3 POU class 4 homeobox 3 -1.39149
CSK c-src tyrosine kinase -1.39052
ZNF781 zinc finger protein 781 -1.38864
AKAP10 A kinase (PRKA) anchor protein 10 -1.38861
ATXN10 ataxin 10 -1.38303
USP54 ubiquitin specific peptidase 54 -1.37927
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -1.37688
TSPAN17 tetraspanin 17 -1.36862
PARP1 poly (ADP-ribose) polymerase 1 -1.35219
PPARG peroxisome proliferator-activated receptor gamma -1.34799
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.3447
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.34314
HSPA2 heat shock 70kDa protein 2 -1.34099
POU2F2 POU class 2 homeobox 2 -1.33781
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -1.33685
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -1.33467
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -1.33242
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -1.33241
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 -1.32482
SOX9 SRY (sex determining region Y)-box 9 -1.32425
ST7 suppression of tumorigenicity 7 -1.32001
APOM apolipoprotein M -1.31579
DPP9 dipeptidyl-peptidase 9 -1.31351
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 -1.31179
SSBP2 single-stranded DNA binding protein 2 -1.30687
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.30668
HOXA4 homeobox A4 -1.30658
VIM vimentin -1.30301
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough -1.30276
LOXL4 lysyl oxidase-like 4 -1.30243
ULBP1 UL16 binding protein 1 -1.29549
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -1.2945
AHR aryl hydrocarbon receptor -1.28813
SERHL serine hydrolase-like (pseudogene) -1.28582
IGFBP5 insulin-like growth factor binding protein 5 -1.28576
ULBP3 UL16 binding protein 3 -1.28557
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma -1.28519
TCF7 transcription factor 7 (T-cell specific, HMG-box) -1.28117
TOX2 TOX high mobility group box family member 2 -1.27783
HSPA8 heat shock 70kDa protein 8 -1.2771
RIMS3 regulating synaptic membrane exocytosis 3 -1.27048
ROGDI rogdi homolog (Drosophila) -1.26651
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -1.26532
EID2 EP300 interacting inhibitor of differentiation 2 -1.26374
GATAD2A GATA zinc finger domain containing 2A -1.25971
POU1F1 POU class 1 homeobox 1 -1.25949
FOXH1 forkhead box H1 -1.25849
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 -1.25428
NRG1 neuregulin 1 -1.25168
PLAGL2 pleiomorphic adenoma gene-like 2 -1.24813
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.2451
SUMO2 small ubiquitin-like modifier 2 -1.24229
GJC1 gap junction protein, gamma 1, 45kDa -1.24165
GGT3P gamma-glutamyltransferase 3 pseudogene -1.24144
DDR2 discoidin domain receptor tyrosine kinase 2 -1.23809
CSNK2B casein kinase 2, beta polypeptide -1.2375
RAB10 RAB10, member RAS oncogene family -1.23645
ACVRL1 activin A receptor type II-like 1 -1.23635
USP6 ubiquitin specific peptidase 6 -1.23579
TRAPPC8 trafficking protein particle complex 8 -1.23463
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.23076
USP34 ubiquitin specific peptidase 34 -1.22806
EYS eyes shut homolog (Drosophila) -1.22544
BCL2L13 BCL2-like 13 (apoptosis facilitator) -1.21333
BCL2L1 BCL2-like 1 -1.2129
CLIC2 chloride intracellular channel 2 -1.21216
IGFBP4 insulin-like growth factor binding protein 4 -1.21008
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough -1.19943
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.195
CCR1 chemokine (C-C motif) receptor 1 -1.19468
CLEC7A C-type lectin domain family 7, member A -1.19436
DPP4 dipeptidyl-peptidase 4 -1.1907
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -1.18737
HOXA9 homeobox A9 -1.18631
KHSRP KH-type splicing regulatory protein -1.18243
PSKH1 protein serine kinase H1 -1.18021
HOMER2 homer scaffolding protein 2 -1.17856
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -1.17837
PKD2 polycystic kidney disease 2 (autosomal dominant) -1.17618
CISH cytokine inducible SH2-containing protein -1.17535
SMAD5 SMAD family member 5 -1.17454
FCRLA Fc receptor-like A -1.16905
ZNF334 zinc finger protein 334 -1.16314
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.16302
RBM17 RNA binding motif protein 17 -1.16228
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -1.16154
TP53 tumor protein p53 -1.1608
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 -1.15728
PPID peptidylprolyl isomerase D -1.15708
GK5 glycerol kinase 5 (putative) -1.15303
ANXA3 annexin A3 -1.15068
ZNF322P1 zinc finger protein 322 pseudogene 1 -1.14923
IFNAR1 interferon (alpha, beta and omega) receptor 1 -1.14921
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -1.1484
INPP5D inositol polyphosphate-5-phosphatase, 145kDa -1.14734
MXI1 MAX interactor 1, dimerization protein -1.14454
ABHD16B abhydrolase domain containing 16B -1.1445
ITPK1 inositol-tetrakisphosphate 1-kinase -1.14273
MT1F metallothionein 1F -1.14104
ABHD16A abhydrolase domain containing 16A -1.14079
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -1.13903
DGKA diacylglycerol kinase, alpha 80kDa -1.13778
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -1.13402
M6PR mannose-6-phosphate receptor (cation dependent) -1.12545
RYR2 ryanodine receptor 2 (cardiac) -1.1218
KIF17 kinesin family member 17 -1.12079
S1PR3 sphingosine-1-phosphate receptor 3 -1.11611
ZNF500 zinc finger protein 500 -1.1145
PFN1 profilin 1 -1.11332
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -1.11225
MECP2 methyl CpG binding protein 2 -1.11178
TPO thyroid peroxidase -1.11108
ZNF320 zinc finger protein 320 -1.10905
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -1.10891
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -1.10667
EIF5B eukaryotic translation initiation factor 5B -1.10272
CARD14 caspase recruitment domain family, member 14 -1.10223
GLUD1 glutamate dehydrogenase 1 -1.1018
AK3 adenylate kinase 3 -1.10069
RICTOR RPTOR independent companion of MTOR, complex 2 -1.10032
SRM spermidine synthase -1.09947
DPEP2 dipeptidase 2 -1.09855
ING2 inhibitor of growth family, member 2 -1.09516
CST2 cystatin SA -1.09302
RGS16 regulator of G-protein signaling 16 -1.09131
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -1.08687
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -1.08667
GGT1 gamma-glutamyltransferase 1 -1.08077
DLX6 distal-less homeobox 6 -1.07854
BCAP29 B-cell receptor-associated protein 29 -1.07808
RNF25 ring finger protein 25 -1.07398
SPRY4 sprouty homolog 4 (Drosophila) -1.07347
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -1.06979
CYSLTR1 cysteinyl leukotriene receptor 1 -1.06254
CAPN2 calpain 2, (m/II) large subunit -1.0607
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1 -1.05894
MFAP1 microfibrillar-associated protein 1 -1.05893
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.0526
CHDH choline dehydrogenase -1.05151
RNMT RNA (guanine-7-) methyltransferase -1.0512
UCK2 uridine-cytidine kinase 2 -1.04983
GAP43 growth associated protein 43 -1.04966
DLG4 discs, large homolog 4 (Drosophila) -1.04959
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -1.04817
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -1.0454
OR1S2 olfactory receptor, family 1, subfamily S, member 2 -1.04498
SP3 Sp3 transcription factor -1.04358
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.03556
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 -1.03464
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -1.03332
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -1.03206
DNM1L dynamin 1-like -1.03196
RYBP RING1 and YY1 binding protein -1.02989
RBP2 retinol binding protein 2, cellular -1.02935
ILF2 interleukin enhancer binding factor 2 -1.02913
QARS glutaminyl-tRNA synthetase -1.02911
RPS4X ribosomal protein S4, X-linked -1.02741
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.02499
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -1.02356
NPC1 Niemann-Pick disease, type C1 -1.02285
CCL24 chemokine (C-C motif) ligand 24 -1.01912
GK glycerol kinase -1.01764
EPHA7 EPH receptor A7 -1.01499
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -1.01482
DPRX divergent-paired related homeobox -1.01464
SLAMF7 SLAM family member 7 -1.01254
JMJD6 jumonji domain containing 6 -1.0115
ADRA2A adrenoceptor alpha 2A -1.01142
CNGB1 cyclic nucleotide gated channel beta 1 -1.0113
ACHE acetylcholinesterase (Yt blood group) -1.01083
RPS9 ribosomal protein S9 -1.01065
MLH1 mutL homolog 1 -1.00931
STX17 syntaxin 17 -1.0074
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -1.00725
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.00598
KRT13 keratin 13, type I -1.00355
ASL argininosuccinate lyase -1.00273
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -1.00206
BNC2 basonuclin 2 -1.0012