COR-L105 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

316 genes with high or low expression in COR-L105 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.33193
EPPIN epididymal peptidase inhibitor 3.21069
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.87839
BICC1 BicC family RNA binding protein 1 2.75213
ARL14 ADP-ribosylation factor-like 14 2.71614
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.66503
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.65536
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.62301
NPY4R neuropeptide Y receptor Y4 2.59724
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.56494
HYAL1 hyaluronoglucosaminidase 1 2.53981
PLAUR plasminogen activator, urokinase receptor 2.47302
SYT12 synaptotagmin XII 2.46535
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.44665
ERO1L ERO1-like (S. cerevisiae) 2.40451
EDA ectodysplasin A 2.33538
FA2H fatty acid 2-hydroxylase 2.32232
ZNF337 zinc finger protein 337 2.18626
TM4SF4 transmembrane 4 L six family member 4 2.18072
ZFAND5 zinc finger, AN1-type domain 5 2.18008
CLCF1 cardiotrophin-like cytokine factor 1 2.16817
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.14722
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.1464
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.11162
PCDHGB5 protocadherin gamma subfamily B, 5 2.07664
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.06879
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.04552
DEFB1 defensin, beta 1 2.04496
GYS1 glycogen synthase 1 (muscle) 2.02665
LBP lipopolysaccharide binding protein 1.97107
MYO1E myosin IE 1.95522
CFHR2 complement factor H-related 2 1.93516
TGFB2 transforming growth factor, beta 2 1.92946
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 1.88131
MYO15B myosin XVB 1.87239
ACADL acyl-CoA dehydrogenase, long chain 1.87191
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 1.87006
SKAP2 src kinase associated phosphoprotein 2 1.86777
ITGB4 integrin, beta 4 1.85233
HBE1 hemoglobin, epsilon 1 1.85178
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.83581
SMOX spermine oxidase 1.82477
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.82086
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 1.79949
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.78772
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.77849
PDE4D phosphodiesterase 4D, cAMP-specific 1.77534
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 1.76863
AKR1D1 aldo-keto reductase family 1, member D1 1.75788
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 1.75567
KLK11 kallikrein-related peptidase 11 1.73704
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 1.7317
PTPRM protein tyrosine phosphatase, receptor type, M 1.72563
AVPI1 arginine vasopressin-induced 1 1.72167
MMP15 matrix metallopeptidase 15 (membrane-inserted) 1.71547
CA9 carbonic anhydrase IX 1.70873
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.70574
HIST1H3D histone cluster 1, H3d 1.70369
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.69677
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.69444
KIAA1109 KIAA1109 1.68866
APLP1 amyloid beta (A4) precursor-like protein 1 1.68574
IL15 interleukin 15 1.68446
HIST1H2BC histone cluster 1, H2bc 1.6835
VEGFA vascular endothelial growth factor A 1.68313
PPARD peroxisome proliferator-activated receptor delta 1.67388
C1RL complement component 1, r subcomponent-like 1.66796
CER1 cerberus 1, DAN family BMP antagonist 1.6594
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.6583
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.65721
ACBD4 acyl-CoA binding domain containing 4 1.65692
SMAD6 SMAD family member 6 1.64797
HIST2H2AA3 histone cluster 2, H2aa3 1.6386
PSG2 pregnancy specific beta-1-glycoprotein 2 1.63393
BAGE B melanoma antigen 1.63253
OLFM4 olfactomedin 4 1.63224
PTGES prostaglandin E synthase 1.63002
GRB14 growth factor receptor-bound protein 14 1.6293
EGLN3 egl-9 family hypoxia-inducible factor 3 1.62737
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 1.61706
CCDC68 coiled-coil domain containing 68 1.61188
CTBP2 C-terminal binding protein 2 1.61113
UPK3B uroplakin 3B 1.60028
ATG4B autophagy related 4B, cysteine peptidase 1.5976
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 1.59446
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding) 1.58096
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.57513
VTN vitronectin 1.57512
ONECUT2 one cut homeobox 2 1.56114
F11 coagulation factor XI 1.55468
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 1.55038
PGK1 phosphoglycerate kinase 1 1.5422
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene 1.53615
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.5352
INVS inversin 1.53469
MT1F metallothionein 1F 1.53439
MPRIP myosin phosphatase Rho interacting protein 1.53186
MT1X metallothionein 1X 1.52831
SMAD2 SMAD family member 2 1.52755
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.52722
VNN1 vanin 1 1.52233
LIF leukemia inhibitory factor 1.52167
DAPK1 death-associated protein kinase 1 1.51936
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.51805
DSG2 desmoglein 2 1.50558
HLA-DMA major histocompatibility complex, class II, DM alpha 1.50545
TGM2 transglutaminase 2 1.50531
CRYGA crystallin, gamma A 1.50446
ADNP2 ADNP homeobox 2 1.50444
ZBTB25 zinc finger and BTB domain containing 25 1.50012
C1S complement component 1, s subcomponent 1.49058
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 1.48611
EHBP1 EH domain binding protein 1 1.48538
PDE8A phosphodiesterase 8A 1.4819
GCA grancalcin, EF-hand calcium binding protein 1.47885
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.4784
DLG5 discs, large homolog 5 (Drosophila) 1.47726
GBE1 glucan (1,4-alpha-), branching enzyme 1 1.47186
KAT2A K(lysine) acetyltransferase 2A 1.47122
WNT1 wingless-type MMTV integration site family, member 1 1.4694
GRIK2 glutamate receptor, ionotropic, kainate 2 1.46742
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.46583
RORC RAR-related orphan receptor C 1.46025
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.45702
MARC2 mitochondrial amidoxime reducing component 2 1.45689
TFPI2 tissue factor pathway inhibitor 2 1.45536
PLSCR4 phospholipid scramblase 4 1.45221
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.44189
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.44008
FAM90A1 family with sequence similarity 90, member A1 1.43925
AKAP3 A kinase (PRKA) anchor protein 3 1.43868
GP6 glycoprotein VI (platelet) 1.43866
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.43568
DHRS9 dehydrogenase/reductase (SDR family) member 9 1.4297
GPI glucose-6-phosphate isomerase 1.42735
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 1.42716
PI3 peptidase inhibitor 3, skin-derived 1.42557
RNASE4 ribonuclease, RNase A family, 4 1.42392

low expression

Symbol Name Standardized Value
MARS methionyl-tRNA synthetase -3.53715
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.53642
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -3.11609
H2AFZ H2A histone family, member Z -3.05819
DCP1A decapping mRNA 1A -3.03169
YARS tyrosyl-tRNA synthetase -2.9348
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit -2.92061
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -2.89025
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.74222
DENR density-regulated protein -2.66863
LSM1 LSM1, U6 small nuclear RNA associated -2.63051
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 -2.59187
ERI3 ERI1 exoribonuclease family member 3 -2.59027
ATAD3A ATPase family, AAA domain containing 3A -2.55048
SOX15 SRY (sex determining region Y)-box 15 -2.54777
ZW10 zw10 kinetochore protein -2.48372
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.45861
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.36512
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.33067
KDM1A lysine (K)-specific demethylase 1A -2.30243
MTMR12 myotubularin related protein 12 -2.27601
MED22 mediator complex subunit 22 -2.26827
RANBP1 RAN binding protein 1 -2.26797
EIF4E eukaryotic translation initiation factor 4E -2.25814
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.24229
TCEA1 transcription elongation factor A (SII), 1 -2.2412
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) -2.23698
SF3A1 splicing factor 3a, subunit 1, 120kDa -2.23301
SFPQ splicing factor proline/glutamine-rich -2.22232
ZFP69B ZFP69 zinc finger protein B -2.22072
EXOSC10 exosome component 10 -2.21661
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.20696
USP1 ubiquitin specific peptidase 1 -2.2046
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -2.18815
TXLNA taxilin alpha -2.17847
PHF10 PHD finger protein 10 -2.17043
CTPS1 CTP synthase 1 -2.16588
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.1567
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -2.12334
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.12172
EWSR1 EWS RNA-binding protein 1 -2.11744
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -2.11265
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) -2.11091
TMX2 thioredoxin-related transmembrane protein 2 -2.10773
LDHB lactate dehydrogenase B -2.06724
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.05795
ZMAT5 zinc finger, matrin-type 5 -2.03839
TATDN2 TatD DNase domain containing 2 -2.03668
UBE2K ubiquitin-conjugating enzyme E2K -2.01293
AGO1 argonaute RISC catalytic component 1 -2.00786
USP19 ubiquitin specific peptidase 19 -2.00617
HOXA2 homeobox A2 -1.9968
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.98002
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -1.97751
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.96513
CDC25A cell division cycle 25A -1.96253
DRG1 developmentally regulated GTP binding protein 1 -1.96201
NUDC nudC nuclear distribution protein -1.96128
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -1.94601
EIF5A eukaryotic translation initiation factor 5A -1.94331
LOC257152 uncharacterized LOC257152 -1.92463
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.92298
TOE1 target of EGR1, member 1 (nuclear) -1.91711
TMED2 transmembrane emp24 domain trafficking protein 2 -1.91593
PISD phosphatidylserine decarboxylase -1.90416
TCEAL2 transcription elongation factor A (SII)-like 2 -1.9014
DCTN2 dynactin 2 (p50) -1.89603
CDH10 cadherin 10, type 2 (T2-cadherin) -1.89599
TARDBP TAR DNA binding protein -1.89017
NASP nuclear autoantigenic sperm protein (histone-binding) -1.89
VLDLR very low density lipoprotein receptor -1.86599
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -1.86583
PITPNB phosphatidylinositol transfer protein, beta -1.85275
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -1.85111
GLMN glomulin, FKBP associated protein -1.84647
TXK TXK tyrosine kinase -1.83467
RAN RAN, member RAS oncogene family -1.80076
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -1.79848
GPS1 G protein pathway suppressor 1 -1.78711
GPKOW G patch domain and KOW motifs -1.779
RANGAP1 Ran GTPase activating protein 1 -1.77461
GPATCH3 G patch domain containing 3 -1.7671
SF3B5 splicing factor 3b, subunit 5, 10kDa -1.75695
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -1.75193
PRPF6 pre-mRNA processing factor 6 -1.74144
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -1.73878
PTDSS1 phosphatidylserine synthase 1 -1.73744
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -1.73671
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -1.73591
NAV1 neuron navigator 1 -1.73014
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -1.72245
ZPR1 ZPR1 zinc finger -1.71751
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.71662
ADSL adenylosuccinate lyase -1.70968
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.70209
WRAP73 WD repeat containing, antisense to TP73 -1.70175
FBXO7 F-box protein 7 -1.70042
KPNA5 karyopherin alpha 5 (importin alpha 6) -1.69676
IMPG2 interphotoreceptor matrix proteoglycan 2 -1.68625
NOL10 nucleolar protein 10 -1.68397
UBE4B ubiquitination factor E4B -1.67984
TARS threonyl-tRNA synthetase -1.67924
STOML2 stomatin (EPB72)-like 2 -1.66376
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.66345
STRN striatin, calmodulin binding protein -1.662
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -1.63696
COPS3 COP9 signalosome subunit 3 -1.63347
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.62488
RPA2 replication protein A2, 32kDa -1.61958
SNRPC small nuclear ribonucleoprotein polypeptide C -1.61908
HAO2 hydroxyacid oxidase 2 (long chain) -1.61232
AMD1 adenosylmethionine decarboxylase 1 -1.60455
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.5978
VCP valosin containing protein -1.59174
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -1.59168
CASC3 cancer susceptibility candidate 3 -1.59002
CTRL chymotrypsin-like -1.58998
TMEM110 transmembrane protein 110 -1.58553
RBX1 ring-box 1, E3 ubiquitin protein ligase -1.58028
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -1.57639
CDCA8 cell division cycle associated 8 -1.57625
SRSF3 serine/arginine-rich splicing factor 3 -1.5751
CHAT choline O-acetyltransferase -1.56901
THOC5 THO complex 5 -1.55921
MTERF3 mitochondrial transcription termination factor 3 -1.55631
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -1.5563
LEFTY1 left-right determination factor 1 -1.55303
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -1.55186
GSTP1 glutathione S-transferase pi 1 -1.54758
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.54162
LYPLA1 lysophospholipase I -1.54046
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -1.53558
ART3 ADP-ribosyltransferase 3 -1.53171
COPZ1 coatomer protein complex, subunit zeta 1 -1.53017
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.52927
FIG4 FIG4 phosphoinositide 5-phosphatase -1.52831
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene -1.523
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.51541
MCM5 minichromosome maintenance complex component 5 -1.51303
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.50858
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -1.50222
EXOG endo/exonuclease (5'-3'), endonuclease G-like -1.50017
AARS alanyl-tRNA synthetase -1.49834
SCNM1 sodium channel modifier 1 -1.49437
STK17B serine/threonine kinase 17b -1.49387
SLN sarcolipin -1.49305
TM2D3 TM2 domain containing 3 -1.49269
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -1.48241
TEX14 testis expressed 14 -1.48206
ZMPSTE24 zinc metallopeptidase STE24 -1.4787
SRP72 signal recognition particle 72kDa -1.47415
SRSF2 serine/arginine-rich splicing factor 2 -1.47359
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.47129
TIMELESS timeless circadian clock -1.47077
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -1.46676
MAEA macrophage erythroblast attacher -1.4647
CDK2 cyclin-dependent kinase 2 -1.46015
CDK4 cyclin-dependent kinase 4 -1.45951
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -1.45929
CCT8 chaperonin containing TCP1, subunit 8 (theta) -1.45538
GZMK granzyme K (granzyme 3; tryptase II) -1.45517
HCFC1 host cell factor C1 -1.45459
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.45248
DHRS7B dehydrogenase/reductase (SDR family) member 7B -1.4521
KLHL18 kelch-like family member 18 -1.44833
ASCC2 activating signal cointegrator 1 complex subunit 2 -1.44759
DNASE2B deoxyribonuclease II beta -1.44541
EXOSC7 exosome component 7 -1.44299
RANGRF RAN guanine nucleotide release factor -1.43745
GOSR2 golgi SNAP receptor complex member 2 -1.43612
FBXO5 F-box protein 5 -1.42897
MTDH metadherin -1.42884
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -1.4286
NEUROD6 neuronal differentiation 6 -1.42697
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.42617
DBR1 debranching RNA lariats 1 -1.4226
AP1B1 adaptor-related protein complex 1, beta 1 subunit -1.41806
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -1.41634