COR-L23 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, large cell (Cell Line Ontology, CLO_0002585)
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Genes

341 genes with high or low expression in COR-L23 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
TEAD4 TEA domain family member 4 3.60177
PARP11 poly (ADP-ribose) polymerase family, member 11 3.60118
TSPAN9 tetraspanin 9 2.94216
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 2.80461
RUVBL1 RuvB-like AAA ATPase 1 2.80316
KISS1 KiSS-1 metastasis-suppressor 2.70257
NPAS2 neuronal PAS domain protein 2 2.37136
PRMT5 protein arginine methyltransferase 5 2.35187
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2.35125
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 2.34433
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.31781
RYK receptor-like tyrosine kinase 2.31329
PAEP progestagen-associated endometrial protein 2.299
TOP1 topoisomerase (DNA) I 2.25894
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.21823
MRPL3 mitochondrial ribosomal protein L3 2.21741
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 2.21285
RPL23AP7 ribosomal protein L23a pseudogene 7 2.20106
CNBP CCHC-type zinc finger, nucleic acid binding protein 2.18489
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.18242
RASA1 RAS p21 protein activator (GTPase activating protein) 1 2.11174
PALB2 partner and localizer of BRCA2 2.08257
SLC41A3 solute carrier family 41, member 3 1.95727
KRT33B keratin 33B, type I 1.93684
UMPS uridine monophosphate synthetase 1.90615
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.90476
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.90083
DKC1 dyskeratosis congenita 1, dyskerin 1.89084
SPATA5L1 spermatogenesis associated 5-like 1 1.86901
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.86671
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.85097
MARCO macrophage receptor with collagenous structure 1.84214
PLAT plasminogen activator, tissue 1.80503
PVT1 Pvt1 oncogene (non-protein coding) 1.77915
MMP9 matrix metallopeptidase 9 1.77628
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1.77048
SAV1 salvador family WW domain containing protein 1 1.76788
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 1.74764
LIPG lipase, endothelial 1.74184
ZXDC ZXD family zinc finger C 1.73761
REN renin 1.73358
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 1.72544
PODXL podocalyxin-like 1.69781
MARK3 MAP/microtubule affinity-regulating kinase 3 1.68275
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.67181
COPG1 coatomer protein complex, subunit gamma 1 1.67164
SRPX2 sushi-repeat containing protein, X-linked 2 1.66373
SLC35F2 solute carrier family 35, member F2 1.66138
NUP37 nucleoporin 37kDa 1.65006
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 1.6477
FLNB filamin B, beta 1.63769
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 1.62628
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.62512
KLF3 Kruppel-like factor 3 (basic) 1.61031
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 1.60852
NUP155 nucleoporin 155kDa 1.60017
ANO1 anoctamin 1, calcium activated chloride channel 1.59984
HBE1 hemoglobin, epsilon 1 1.59686
KRAS Kirsten rat sarcoma viral oncogene homolog 1.59522
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 1.59129
DOCK9 dedicator of cytokinesis 9 1.58568
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 1.58502
KRT34 keratin 34, type I 1.58186
ABHD10 abhydrolase domain containing 10 1.57792
KCTD5 potassium channel tetramerization domain containing 5 1.57772
DUSP5 dual specificity phosphatase 5 1.57241
LONRF3 LON peptidase N-terminal domain and ring finger 3 1.57021
KRT75 keratin 75, type II 1.55734
DNMBP dynamin binding protein 1.55337
ITCH itchy E3 ubiquitin protein ligase 1.55294
HBEGF heparin-binding EGF-like growth factor 1.54716
TMOD3 tropomodulin 3 (ubiquitous) 1.53606
FGD6 FYVE, RhoGEF and PH domain containing 6 1.53472
KRT33A keratin 33A, type I 1.53336
BRIX1 BRX1, biogenesis of ribosomes 1.53327
GJA5 gap junction protein, alpha 5, 40kDa 1.52334
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.52283
MPI mannose phosphate isomerase 1.521
ESM1 endothelial cell-specific molecule 1 1.51933
AKAP12 A kinase (PRKA) anchor protein 12 1.49556
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1.4797
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 1.47613
UBA5 ubiquitin-like modifier activating enzyme 5 1.47553
PRSS1 protease, serine, 1 (trypsin 1) 1.46949
DAP death-associated protein 1.46918
UBFD1 ubiquitin family domain containing 1 1.4604
GALK2 galactokinase 2 1.45386
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.45052
LAMA3 laminin, alpha 3 1.44868
AVEN apoptosis, caspase activation inhibitor 1.4476
FGF13 fibroblast growth factor 13 1.44704
ACP6 acid phosphatase 6, lysophosphatidic 1.44428
AQR aquarius intron-binding spliceosomal factor 1.44251
CAB39 calcium binding protein 39 1.4344
ANGEL1 angel homolog 1 (Drosophila) 1.43198
WNT7A wingless-type MMTV integration site family, member 7A 1.42172
ASPH aspartate beta-hydroxylase 1.42004

low expression

Symbol Name Standardized Value
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -3.53725
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase -3.52977
ZNF235 zinc finger protein 235 -3.21742
FBXL15 F-box and leucine-rich repeat protein 15 -3.1279
SCAMP3 secretory carrier membrane protein 3 -3.08102
MYT1 myelin transcription factor 1 -2.9154
AMHR2 anti-Mullerian hormone receptor, type II -2.9119
ADAM12 ADAM metallopeptidase domain 12 -2.82495
HAUS5 HAUS augmin-like complex, subunit 5 -2.72862
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 -2.68327
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.66116
NPY5R neuropeptide Y receptor Y5 -2.62769
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -2.52181
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.47307
SIGLEC8 sialic acid binding Ig-like lectin 8 -2.4405
COL5A2 collagen, type V, alpha 2 -2.41585
HOXA5 homeobox A5 -2.41518
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -2.40334
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) -2.39826
ATRNL1 attractin-like 1 -2.3961
MGC2889 uncharacterized protein MGC2889 -2.34352
TM4SF4 transmembrane 4 L six family member 4 -2.33571
GVINP1 GTPase, very large interferon inducible pseudogene 1 -2.32063
JCHAIN joining chain of multimeric IgA and IgM -2.2961
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -2.27454
MUC3B mucin 3B, cell surface associated -2.24375
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -2.2423
SIRT2 sirtuin 2 -2.23515
HHAT hedgehog acyltransferase -2.23293
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.22027
HYMAI hydatidiform mole associated and imprinted (non-protein coding) -2.21109
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.20588
CLSPN claspin -2.19272
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.18876
GIPC2 GIPC PDZ domain containing family, member 2 -2.17782
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled -2.17038
IL17A interleukin 17A -2.16214
TACR1 tachykinin receptor 1 -2.15369
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.14466
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.14257
MXD3 MAX dimerization protein 3 -2.13969
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.11433
KLK15 kallikrein-related peptidase 15 -2.1005
LRRN3 leucine rich repeat neuronal 3 -2.08914
LOC257152 uncharacterized LOC257152 -2.07742
FGF2 fibroblast growth factor 2 (basic) -2.07211
SPATA1 spermatogenesis associated 1 -2.07146
MBD3 methyl-CpG binding domain protein 3 -2.04883
BIN2 bridging integrator 2 -2.04645
ASIC4 acid sensing (proton gated) ion channel family member 4 -2.04488
ZNF446 zinc finger protein 446 -2.0433
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) -2.03923
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.03898
FLT1 fms-related tyrosine kinase 1 -2.03641
NENF neudesin neurotrophic factor -2.02223
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -1.99624
NSG1 neuron specific gene family member 1 -1.9906
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -1.98808
NRN1 neuritin 1 -1.97304
ERN1 endoplasmic reticulum to nucleus signaling 1 -1.97301
F5 coagulation factor V (proaccelerin, labile factor) -1.96954
SAA3P serum amyloid A3 pseudogene -1.96414
BAD BCL2-associated agonist of cell death -1.9638
SDHAF3 succinate dehydrogenase complex assembly factor 3 -1.95769
DAPK2 death-associated protein kinase 2 -1.95353
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -1.94356
TTLL7 tubulin tyrosine ligase-like family member 7 -1.94292
MAN1C1 mannosidase, alpha, class 1C, member 1 -1.93062
ZNF37BP zinc finger protein 37B, pseudogene -1.92118
HIST1H2AM histone cluster 1, H2am -1.92056
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -1.91362
BRSK2 BR serine/threonine kinase 2 -1.90359
ZNF442 zinc finger protein 442 -1.90192
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -1.8945
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -1.89201
RCN1 reticulocalbin 1, EF-hand calcium binding domain -1.87533
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.86888
PLN phospholamban -1.86054
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.85567
GH1 growth hormone 1 -1.84933
SLC17A4 solute carrier family 17, member 4 -1.84568
ALPPL2 alkaline phosphatase, placental-like 2 -1.84506
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -1.84397
CRYBA2 crystallin, beta A2 -1.83969
ACE2 angiotensin I converting enzyme 2 -1.83658
YIPF3 Yip1 domain family, member 3 -1.83581
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -1.82994
IRX5 iroquois homeobox 5 -1.82891
ETV2 ets variant 2 -1.82579
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.82128
PDYN prodynorphin -1.82088
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 -1.81828
LIME1 Lck interacting transmembrane adaptor 1 -1.8101
SMAD9 SMAD family member 9 -1.80761
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene -1.8046
SESN1 sestrin 1 -1.80294
ZFYVE16 zinc finger, FYVE domain containing 16 -1.80236
VAX2 ventral anterior homeobox 2 -1.79193
CLEC3B C-type lectin domain family 3, member B -1.79162
SCN1B sodium channel, voltage gated, type I beta subunit -1.77841
KIAA0232 KIAA0232 -1.77635
IL6 interleukin 6 -1.77175
RORC RAR-related orphan receptor C -1.7663
RGS9 regulator of G-protein signaling 9 -1.75895
ESR1 estrogen receptor 1 -1.75728
GRIK1 glutamate receptor, ionotropic, kainate 1 -1.75218
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -1.7473
SLC45A2 solute carrier family 45, member 2 -1.74446
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -1.73348
GH2 growth hormone 2 -1.72637
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 -1.71584
ZNF407 zinc finger protein 407 -1.70708
MYF5 myogenic factor 5 -1.70623
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -1.69
ANO3 anoctamin 3 -1.68529
NCOA1 nuclear receptor coactivator 1 -1.68321
ATP9B ATPase, class II, type 9B -1.68004
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 -1.67989
CCDC92 coiled-coil domain containing 92 -1.67881
TOR3A torsin family 3, member A -1.67751
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -1.67463
FASTK Fas-activated serine/threonine kinase -1.66975
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -1.66817
AES amino-terminal enhancer of split -1.66486
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 -1.66334
ZNF480 zinc finger protein 480 -1.6543
PLEK pleckstrin -1.65408
FSCN3 fascin actin-bundling protein 3, testicular -1.65351
ZXDB zinc finger, X-linked, duplicated B -1.65039
HESX1 HESX homeobox 1 -1.63999
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -1.63998
NEU3 sialidase 3 (membrane sialidase) -1.63984
RIC3 RIC3 acetylcholine receptor chaperone -1.63965
MKRN3 makorin ring finger protein 3 -1.63722
PKNOX2 PBX/knotted 1 homeobox 2 -1.63457
SHOX2 short stature homeobox 2 -1.63276
FZD10 frizzled class receptor 10 -1.63063
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.62923
ZNF189 zinc finger protein 189 -1.62693
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -1.62224
FKBP1B FK506 binding protein 1B, 12.6 kDa -1.62211
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -1.6139
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -1.61205
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 -1.60626
IL10 interleukin 10 -1.60391
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -1.5983
CABP2 calcium binding protein 2 -1.59707
TECTA tectorin alpha -1.59646
HOXB3 homeobox B3 -1.59448
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.59172
ELOVL2 ELOVL fatty acid elongase 2 -1.59069
PHEX phosphate regulating endopeptidase homolog, X-linked -1.59031
FAAH fatty acid amide hydrolase -1.58314
SLITRK5 SLIT and NTRK-like family, member 5 -1.583
ZSWIM1 zinc finger, SWIM-type containing 1 -1.58194
HOXA7 homeobox A7 -1.58187
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -1.57482
SNTA1 syntrophin, alpha 1 -1.57211
AMPD1 adenosine monophosphate deaminase 1 -1.56646
DGCR14 DiGeorge syndrome critical region gene 14 -1.56533
ARR3 arrestin 3, retinal (X-arrestin) -1.56216
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 -1.56207
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -1.55772
IGFALS insulin-like growth factor binding protein, acid labile subunit -1.55504
SPAG11B sperm associated antigen 11B -1.55434
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.55237
REEP2 receptor accessory protein 2 -1.55236
FOXL1 forkhead box L1 -1.55183
LALBA lactalbumin, alpha- -1.54514
ZNF132 zinc finger protein 132 -1.54419
MEGF9 multiple EGF-like-domains 9 -1.54195
TMPRSS5 transmembrane protease, serine 5 -1.53135
MYO3A myosin IIIA -1.52926
GP2 glycoprotein 2 (zymogen granule membrane) -1.52907
CYHR1 cysteine/histidine-rich 1 -1.52793
CPT1A carnitine palmitoyltransferase 1A (liver) -1.52371
PTMS parathymosin -1.52368
MAP2K6 mitogen-activated protein kinase kinase 6 -1.52294
GPR183 G protein-coupled receptor 183 -1.52086
LHFP lipoma HMGIC fusion partner -1.52029
HDAC4 histone deacetylase 4 -1.51979
EDF1 endothelial differentiation-related factor 1 -1.51948
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -1.51684
ARHGAP33 Rho GTPase activating protein 33 -1.51002
GRM6 glutamate receptor, metabotropic 6 -1.50737
ERCC8 excision repair cross-complementation group 8 -1.5061
IGHD immunoglobulin heavy constant delta -1.50551
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -1.49437
TFDP3 transcription factor Dp family, member 3 -1.4939
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.49239
DMXL1 Dmx-like 1 -1.49231
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 -1.49169
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -1.4916
MAP2 microtubule-associated protein 2 -1.49107
CA3 carbonic anhydrase III -1.4901
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 -1.48866
GPR1 G protein-coupled receptor 1 -1.48864
TP53TG1 TP53 target 1 (non-protein coding) -1.48683
IDE insulin-degrading enzyme -1.48642
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.48487
HGFAC HGF activator -1.48058
ZSCAN31 zinc finger and SCAN domain containing 31 -1.48042
EIF5A2 eukaryotic translation initiation factor 5A2 -1.47716
LPAR3 lysophosphatidic acid receptor 3 -1.47641
GPR37L1 G protein-coupled receptor 37 like 1 -1.47553
UNC119 unc-119 homolog (C. elegans) -1.47455
VNN2 vanin 2 -1.47116
LRMP lymphoid-restricted membrane protein -1.4702
SCUBE2 signal peptide, CUB domain, EGF-like 2 -1.46971
CSN3 casein kappa -1.46693
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.46541
SRF serum response factor (c-fos serum response element-binding transcription factor) -1.46391
CAPN6 calpain 6 -1.46127
CNTD2 cyclin N-terminal domain containing 2 -1.46034
MAGEB1 melanoma antigen family B1 -1.45956
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2 -1.45879
ZFP37 ZFP37 zinc finger protein -1.45838
CASKIN2 CASK interacting protein 2 -1.45571
GRM4 glutamate receptor, metabotropic 4 -1.45404
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -1.45239
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -1.45228
RAB35 RAB35, member RAS oncogene family -1.45143
ATOH1 atonal homolog 1 (Drosophila) -1.44958
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -1.44908
FAM215A family with sequence similarity 215, member A (non-protein coding) -1.44742
TRIM31 tripartite motif containing 31 -1.44667
RBM23 RNA binding motif protein 23 -1.44666
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.44043
C8A complement component 8, alpha polypeptide -1.43795
KCNK10 potassium channel, two pore domain subfamily K, member 10 -1.43774
CCDC33 coiled-coil domain containing 33 -1.43668
EVL Enah/Vasp-like -1.4366
CTNND2 catenin (cadherin-associated protein), delta 2 -1.43658
MXRA5 matrix-remodelling associated 5 -1.43624
IFNAR2 interferon (alpha, beta and omega) receptor 2 -1.43574
PSG5 pregnancy specific beta-1-glycoprotein 5 -1.43433
TLL1 tolloid-like 1 -1.43175
TSNAX translin-associated factor X -1.42989
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -1.42944
TRPC6 transient receptor potential cation channel, subfamily C, member 6 -1.4264
CBX2 chromobox homolog 2 -1.42527
PPP1R16B protein phosphatase 1, regulatory subunit 16B -1.42102
PROP1 PROP paired-like homeobox 1 -1.41814
SCAND1 SCAN domain containing 1 -1.41762