| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the CP-319743-7486 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ADAM7 | ADAM metallopeptidase domain 7 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHI1 | Abelson helper integration site 1 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARRB1 | arrestin, beta 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CARD9 | caspase recruitment domain family, member 9 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLTC | clathrin, heavy chain (Hc) |
| COPA | coatomer protein complex, subunit alpha |
| CRMP1 | collapsin response mediator protein 1 |
| CRYM | crystallin, mu |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| ECE1 | endothelin converting enzyme 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ESR1 | estrogen receptor 1 |
| FEM1B | fem-1 homolog b (C. elegans) |
| FLOT1 | flotillin 1 |
| FLOT2 | flotillin 2 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GFI1 | growth factor independent 1 transcription repressor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR143 | G protein-coupled receptor 143 |
| GYG2 | glycogenin 2 |
| HBP1 | HMG-box transcription factor 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIF21B | kinesin family member 21B |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LCT | lactase |
| LHX2 | LIM homeobox 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MCL1 | myeloid cell leukemia 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED25 | mediator complex subunit 25 |
| MEF2D | myocyte enhancer factor 2D |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MST1L | macrophage stimulating 1-like |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUDCD3 | NudC domain containing 3 |
| OGFR | opioid growth factor receptor |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PKP2 | plakophilin 2 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCRN3 | secernin 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNX13 | sorting nexin 13 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STMN1 | stathmin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUSD5 | sushi domain containing 5 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM259 | transmembrane protein 259 |
| TRIM23 | tripartite motif containing 23 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFA | vascular endothelial growth factor A |
| WSCD1 | WSC domain containing 1 |
| ZNF350 | zinc finger protein 350 |
| ZNF783 | zinc finger family member 783 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACPP | acid phosphatase, prostate |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFAP1 | actin filament associated protein 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ART1 | ADP-ribosyltransferase 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BARX2 | BARX homeobox 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC121 | coiled-coil domain containing 121 |
| CD48 | CD48 molecule |
| CERS4 | ceramide synthase 4 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLGN | calmegin |
| CNTFR | ciliary neurotrophic factor receptor |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEFA4 | defensin, alpha 4, corticostatin |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GPR157 | G protein-coupled receptor 157 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BM | histone cluster 1, H2bm |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA3 | homeobox A3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI35 | interferon-induced protein 35 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INO80D | INO80 complex subunit D |
| JMJD4 | jumonji domain containing 4 |
| JRKL | JRK-like |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LIN7B | lin-7 homolog B (C. elegans) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAK | male germ cell-associated kinase |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC2889 | uncharacterized protein MGC2889 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NIPAL3 | NIPA-like domain containing 3 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| ONECUT2 | one cut homeobox 2 |
| PADI3 | peptidyl arginine deiminase, type III |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCDHA5 | protocadherin alpha 5 |
| PLCD1 | phospholipase C, delta 1 |
| PODNL1 | podocan-like 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RASIP1 | Ras interacting protein 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RLN1 | relaxin 1 |
| RNF122 | ring finger protein 122 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SETD1A | SET domain containing 1A |
| SIRT6 | sirtuin 6 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| STXBP5L | syntaxin binding protein 5-like |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TCTN2 | tectonic family member 2 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM127 | transmembrane protein 127 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRAIP | TRAF interacting protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UCN | urocortin |
| UNC119 | unc-119 homolog (C. elegans) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF324 | zinc finger protein 324 |
| ZNF35 | zinc finger protein 35 |
| ZNF365 | zinc finger protein 365 |
| ZNF492 | zinc finger protein 492 |
| ZNF76 | zinc finger protein 76 |
| ZNF787 | zinc finger protein 787 |