CP-319743-7491 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the CP-319743-7491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADCK2 aarF domain containing kinase 2
ADRBK1 adrenergic, beta, receptor kinase 1
AHNAK AHNAK nucleoprotein
AKAP7 A kinase (PRKA) anchor protein 7
ANXA10 annexin A10
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARL14 ADP-ribosylation factor-like 14
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BTBD18 BTB (POZ) domain containing 18
C11ORF30 chromosome 11 open reading frame 30
C1ORF116 chromosome 1 open reading frame 116
C9ORF116 chromosome 9 open reading frame 116
C9ORF156 chromosome 9 open reading frame 156
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNO cyclin O
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC14B cell division cycle 14B
CDIP1 cell death-inducing p53 target 1
CDKL3 cyclin-dependent kinase-like 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CGREF1 cell growth regulator with EF-hand domain 1
CIB2 calcium and integrin binding family member 2
CNGB3 cyclic nucleotide gated channel beta 3
COL3A1 collagen, type III, alpha 1
CTH cystathionine gamma-lyase
DEDD death effector domain containing
DENND2A DENN/MADD domain containing 2A
DHODH dihydroorotate dehydrogenase (quinone)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMTN dematin actin binding protein
DNPEP aspartyl aminopeptidase
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EXD3 exonuclease 3'-5' domain containing 3
FABP4 fatty acid binding protein 4, adipocyte
FAM184A family with sequence similarity 184, member A
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GK glycerol kinase
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTCD glutathione S-transferase, C-terminal domain containing
HAUS6 HAUS augmin-like complex, subunit 6
HEMK1 HemK methyltransferase family member 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
JUND jun D proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
KCTD20 potassium channel tetramerization domain containing 20
KLF13 Kruppel-like factor 13
LAMA4 laminin, alpha 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MEIS3P1 Meis homeobox 3 pseudogene 1
NCAPH2 non-SMC condensin II complex, subunit H2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEX7 peroxisomal biogenesis factor 7
PKP2 plakophilin 2
PRUNE prune exopolyphosphatase
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB26 RAB26, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RNASEH2B ribonuclease H2, subunit B
SBF1 SET binding factor 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETDB1 SET domain, bifurcated 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SS18 synovial sarcoma translocation, chromosome 18
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCTN1 tectonic family member 1
TEX261 testis expressed 261
TMEM259 transmembrane protein 259
TRAPPC10 trafficking protein particle complex 10
TRIM9 tripartite motif containing 9
TSKU tsukushi, small leucine rich proteoglycan
UBE3B ubiquitin protein ligase E3B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
YLPM1 YLP motif containing 1
ZNF112 zinc finger protein 112
ZNF778 zinc finger protein 778
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AFAP1 actin filament associated protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARRB1 arrestin, beta 1
ATG10 autophagy related 10
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
C22ORF46 chromosome 22 open reading frame 46
CARD9 caspase recruitment domain family, member 9
CASZ1 castor zinc finger 1
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD70 CD70 molecule
CD82 CD82 molecule
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CISH cytokine inducible SH2-containing protein
CLEC2B C-type lectin domain family 2, member B
CLSTN3 calsyntenin 3
CNTD2 cyclin N-terminal domain containing 2
CTGF connective tissue growth factor
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DENND3 DENN/MADD domain containing 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP13 dual specificity phosphatase 13
EIF5A2 eukaryotic translation initiation factor 5A2
EPN1 epsin 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP6 FK506 binding protein 6, 36kDa
FLT3 fms-related tyrosine kinase 3
FMO4 flavin containing monooxygenase 4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L galactosidase, beta 1-like
GMIP GEM interacting protein
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HHLA1 HERV-H LTR-associating 1
HIST1H4C histone cluster 1, H4c
HSPB8 heat shock 22kDa protein 8
IFT54 intraflagellar transport 54
IL11RA interleukin 11 receptor, alpha
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LGALS4 lectin, galactoside-binding, soluble, 4
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MED9 mediator complex subunit 9
MEGF8 multiple EGF-like-domains 8
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP10 matrix metallopeptidase 10
MTERF4 mitochondrial transcription termination factor 4
MXRA8 matrix-remodelling associated 8
MYH15 myosin, heavy chain 15
NDE1 nudE neurodevelopment protein 1
NT5M 5',3'-nucleotidase, mitochondrial
OR7A10 olfactory receptor, family 7, subfamily A, member 10
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PCBP4 poly(rC) binding protein 4
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIP prolactin-induced protein
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLG plasminogen
PODNL1 podocan-like 1
PRF1 perforin 1 (pore forming protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF43 ring finger protein 43
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCRG1 stimulator of chondrogenesis 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SNRPN small nuclear ribonucleoprotein polypeptide N
SP4 Sp4 transcription factor
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBX19 T-box 19
TCP11 t-complex 11, testis-specific
TENM1 teneurin transmembrane protein 1
TESK2 testis-specific kinase 2
TM4SF5 transmembrane 4 L six family member 5
TMEM62 transmembrane protein 62
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TUBA3C tubulin, alpha 3c
TXK TXK tyrosine kinase
WT1-AS WT1 antisense RNA
ZNF219 zinc finger protein 219
ZNF226 zinc finger protein 226
ZNF276 zinc finger protein 276
ZNF480 zinc finger protein 480