CP-320650-01-4379 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the CP-320650-01-4379 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACRV1 acrosomal vesicle protein 1
ADORA1 adenosine A1 receptor
ADRA1A adrenoceptor alpha 1A
AGO4 argonaute RISC catalytic component 4
BCL2 B-cell CLL/lymphoma 2
BST2 bone marrow stromal cell antigen 2
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF53 chromosome 17 open reading frame 53
C17ORF59 chromosome 17 open reading frame 59
CALD1 caldesmon 1
CCDC57 coiled-coil domain containing 57
CCL5 chemokine (C-C motif) ligand 5
CD84 CD84 molecule
CLEC7A C-type lectin domain family 7, member A
CLPS colipase, pancreatic
COL1A1 collagen, type I, alpha 1
COL6A2 collagen, type VI, alpha 2
CT62 cancer/testis antigen 62
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYTH1 cytohesin 1
DCAF4 DDB1 and CUL4 associated factor 4
DRD2 dopamine receptor D2
DUSP13 dual specificity phosphatase 13
ECM1 extracellular matrix protein 1
ETV1 ets variant 1
FAM182B family with sequence similarity 182, member B
FBXO24 F-box protein 24
FER1L4 fer-1-like family member 4, pseudogene (functional)
FRMD1 FERM domain containing 1
FRMD8 FERM domain containing 8
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HMGN5 high mobility group nucleosome binding domain 5
HOXA1 homeobox A1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFNA17 interferon, alpha 17
IGKV3-20 immunoglobulin kappa variable 3-20
IGL immunoglobulin lambda locus
IMPG2 interphotoreceptor matrix proteoglycan 2
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KRT2 keratin 2, type II
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMNB1 lamin B1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MEGF6 multiple EGF-like-domains 6
MFGE8 milk fat globule-EGF factor 8 protein
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLXIP MLX interacting protein
MORN1 MORN repeat containing 1
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX2-5 NK2 homeobox 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11X protocadherin 11 X-linked
PCDHGC3 protocadherin gamma subfamily C, 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PML promyelocytic leukemia
POF1B premature ovarian failure, 1B
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRSS2 protease, serine, 2 (trypsin 2)
RBM5 RNA binding motif protein 5
SERHL2 serine hydrolase-like 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC17A4 solute carrier family 17, member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMG7-AS1 SMG7 antisense RNA 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
TACSTD2 tumor-associated calcium signal transducer 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TTC39A tetratricopeptide repeat domain 39A
TTLL3 tubulin tyrosine ligase-like family member 3
TTLL7 tubulin tyrosine ligase-like family member 7
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GALT alpha 1,4-galactosyltransferase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTA1 actin, alpha 1, skeletal muscle
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARC activity-regulated cytoskeleton-associated protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARR3 arrestin 3, retinal (X-arrestin)
ASAP1-IT1 ASAP1 intronic transcript 1
BIRC7 baculoviral IAP repeat containing 7
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CCDC134 coiled-coil domain containing 134
CD79B CD79b molecule, immunoglobulin-associated beta
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH18 cadherin 18, type 2
CES1 carboxylesterase 1
CLDN1 claudin 1
CNTNAP1 contactin associated protein 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DAGLA diacylglycerol lipase, alpha
DLK2 delta-like 2 homolog (Drosophila)
DNASE1L2 deoxyribonuclease I-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
DPYS dihydropyrimidinase
DRD1 dopamine receptor D1
EDAR ectodysplasin A receptor
EGFL7 EGF-like-domain, multiple 7
ERO1LB ERO1-like beta (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
FLJ22184
FOXI1 forkhead box I1
FSHB follicle stimulating hormone, beta polypeptide
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAS2 growth arrest-specific 2
GFI1 growth factor independent 1 transcription repressor
GPR39 G protein-coupled receptor 39
GREB1L growth regulation by estrogen in breast cancer-like
HAMP hepcidin antimicrobial peptide
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HOXC13 homeobox C13
HOXC5 homeobox C5
HOXD11 homeobox D11
IFNA14 interferon, alpha 14
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL2 interleukin 2
ISL1 ISL LIM homeobox 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1462 KIAA1462
KLHL29 kelch-like family member 29
KRT9 keratin 9, type I
LAX1 lymphocyte transmembrane adaptor 1
LGALS9 lectin, galactoside-binding, soluble, 9
LMTK1 lemur tail kinase 1
LMTK2 lemur tyrosine kinase 2
LRRTM2 leucine rich repeat transmembrane neuronal 2
LYPLA2P1 lysophospholipase II pseudogene 1
MAPK10 mitogen-activated protein kinase 10
MBTD1 mbt domain containing 1
MEFV Mediterranean fever
MGC2889 uncharacterized protein MGC2889
MSI1 musashi RNA-binding protein 1
NCALD neurocalcin delta
OSMR oncostatin M receptor
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHA5 protocadherin alpha 5
PCDHB3 protocadherin beta 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PICK1 protein interacting with PRKCA 1
PIPOX pipecolic acid oxidase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POU3F2 POU class 3 homeobox 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAI2 retinoic acid induced 2
RNF2 ring finger protein 2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SCARA3 scavenger receptor class A, member 3
SECTM1 secreted and transmembrane 1
SETBP1 SET binding protein 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
STEAP4 STEAP family member 4
TM4SF5 transmembrane 4 L six family member 5
TPSG1 tryptase gamma 1
VEGFB vascular endothelial growth factor B
ZIC3 Zic family member 3
ZNF205 zinc finger protein 205
ZNF304 zinc finger protein 304
ZNF41 zinc finger protein 41