CP-645525-01-7522 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the CP-645525-01-7522 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
APC adenomatous polyposis coli
APOLD1 apolipoprotein L domain containing 1
AQP3 aquaporin 3 (Gill blood group)
ARHGAP1 Rho GTPase activating protein 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP9A ATPase, class II, type 9A
C14ORF93 chromosome 14 open reading frame 93
CCDC93 coiled-coil domain containing 93
CD46 CD46 molecule, complement regulatory protein
CDH18 cadherin 18, type 2
CDV3 CDV3 homolog (mouse)
CLCN2 chloride channel, voltage-sensitive 2
COX11 COX11 cytochrome c oxidase copper chaperone
CTAGE9 CTAGE family, member 9
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DVL2 dishevelled segment polarity protein 2
FAS Fas cell surface death receptor
FCAR Fc fragment of IgA receptor
FER fer (fps/fes related) tyrosine kinase
FH fumarate hydratase
FNDC3A fibronectin type III domain containing 3A
FOSL2 FOS-like antigen 2
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GOLGA8A golgin A8 family, member A
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HIST1H4D histone cluster 1, H4d
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMHA1 histocompatibility (minor) HA-1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IDS iduronate 2-sulfatase
IFT27 intraflagellar transport 27
ING4 inhibitor of growth family, member 4
INSIG1 insulin induced gene 1
ITGB4 integrin, beta 4
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0586 KIAA0586
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MON2 MON2 homolog (S. cerevisiae)
MVP major vault protein
NBR1 neighbor of BRCA1 gene 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXT2 nuclear transport factor 2-like export factor 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAWR PRKC, apoptosis, WT1, regulator
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM4 PDZ and LIM domain 4
PHTF2 putative homeodomain transcription factor 2
PICALM phosphatidylinositol binding clathrin assembly protein
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRKCE protein kinase C, epsilon
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB35 RAB35, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RARG retinoic acid receptor, gamma
RCAN1 regulator of calcineurin 1
RNASEH2B ribonuclease H2, subunit B
RNF19B ring finger protein 19B
RNF43 ring finger protein 43
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCARB2 scavenger receptor class B, member 2
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SIX1 SIX homeobox 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SOX15 SRY (sex determining region Y)-box 15
SOX9 SRY (sex determining region Y)-box 9
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQLE squalene epoxidase
ST20 suppressor of tumorigenicity 20
STON1 stonin 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TICAM1 toll-like receptor adaptor molecule 1
TMEM259 transmembrane protein 259
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOX4 TOX high mobility group box family member 4
TSPAN1 tetraspanin 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF227 zinc finger protein 227
ZNF665 zinc finger protein 665

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTL8 actin-like 8
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AHNAK2 AHNAK nucleoprotein 2
AMPD1 adenosine monophosphate deaminase 1
ANXA2P3 annexin A2 pseudogene 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC6 armadillo repeat containing 6
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BBS7 Bardet-Biedl syndrome 7
BGLAP bone gamma-carboxyglutamate (gla) protein
BTNL3 butyrophilin-like 3
C11ORF30 chromosome 11 open reading frame 30
C1QB complement component 1, q subcomponent, B chain
C9 complement component 9
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC71 coiled-coil domain containing 71
CCL17 chemokine (C-C motif) ligand 17
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CENPO centromere protein O
CRYL1 crystallin, lambda 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DUSP26 dual specificity phosphatase 26 (putative)
DYSF dysferlin
EIF5A2 eukaryotic translation initiation factor 5A2
EMID1 EMI domain containing 1
EXD3 exonuclease 3'-5' domain containing 3
FAM110B family with sequence similarity 110, member B
FBXO22 F-box protein 22
FOXF2 forkhead box F2
FPGS folylpolyglutamate synthase
GADD45G growth arrest and DNA-damage-inducible, gamma
GLCE glucuronic acid epimerase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HDAC11 histone deacetylase 11
HIST1H2BM histone cluster 1, H2bm
IL15RA interleukin 15 receptor, alpha
INPPL1 inositol polyphosphate phosphatase-like 1
ITGA8 integrin, alpha 8
ITM2C integral membrane protein 2C
KATNBL1 katanin p80 subunit B-like 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LOC100131510 uncharacterized LOC100131510
LRP3 low density lipoprotein receptor-related protein 3
MCOLN3 mucolipin 3
MMRN2 multimerin 2
MRPL44 mitochondrial ribosomal protein L44
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MXD3 MAX dimerization protein 3
NAV2 neuron navigator 2
NEK11 NIMA-related kinase 11
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2H1 olfactory receptor, family 2, subfamily H, member 1
PALM paralemmin
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB13 protocadherin beta 13
PITX2 paired-like homeodomain 2
PLTP phospholipid transfer protein
POLL polymerase (DNA directed), lambda
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RPL13P5 ribosomal protein L13 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SFTPD surfactant protein D
SIRT6 sirtuin 6
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLPI secretory leukocyte peptidase inhibitor
SOBP sine oculis binding protein homolog (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STAG3 stromal antigen 3
SYNDIG1 synapse differentiation inducing 1
TCP10L t-complex 10-like
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
TXLNG taxilin gamma
UCN urocortin
VASH1 vasohibin 1
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324