CP-645525-01-7527 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the CP-645525-01-7527 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
ATAD5 ATPase family, AAA domain containing 5
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAIAP2 BAI1-associated protein 2
BMP1 bone morphogenetic protein 1
BTBD7 BTB (POZ) domain containing 7
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD47 CD47 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDV3 CDV3 homolog (mouse)
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL6A1 collagen, type VI, alpha 1
CTAGE5 CTAGE family, member 5
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGCR2 DiGeorge syndrome critical region gene 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ECE1 endothelin converting enzyme 1
EIF3M eukaryotic translation initiation factor 3, subunit M
EN1 engrailed homeobox 1
EN2 engrailed homeobox 2
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVI5 ecotropic viral integration site 5
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FBXO38 F-box protein 38
FGFR1OP FGFR1 oncogene partner
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
FLOT2 flotillin 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATA3 GATA binding protein 3
GPALPP1 GPALPP motifs containing 1
GPR176 G protein-coupled receptor 176
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4C lysine (K)-specific demethylase 4C
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
MOXD1 monooxygenase, DBH-like 1
MTAP methylthioadenosine phosphorylase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NID1 nidogen 1
OGFR opioid growth factor receptor
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCIF1 PDX1 C-terminal inhibiting factor 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLXNA3 plexin A3
PLXND1 plexin D1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRSS8 protease, serine, 8
RGS4 regulator of G-protein signaling 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCIN scinderin
SEC24D SEC24 family member D
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STAG3 stromal antigen 3
STX6 syntaxin 6
SURF1 surfeit 1
TBC1D22A TBC1 domain family, member 22A
TBXAS1 thromboxane A synthase 1 (platelet)
THBS3 thrombospondin 3
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF4 TNF receptor-associated factor 4
TRAPPC9 trafficking protein particle complex 9
TRIM25 tripartite motif containing 25
TWF1 twinfilin actin binding protein 1
UBOX5 U-box domain containing 5
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
YPEL1 yippee-like 1 (Drosophila)
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT5 zinc finger, matrin-type 5
ZNF350 zinc finger protein 350
ZNF480 zinc finger protein 480
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APH1A APH1A gamma secretase subunit
ARHGAP22 Rho GTPase activating protein 22
BAHD1 bromo adjacent homology domain containing 1
BAX BCL2-associated X protein
BBS10 Bardet-Biedl syndrome 10
BDNF brain-derived neurotrophic factor
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C14ORF79 chromosome 14 open reading frame 79
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C6ORF47 chromosome 6 open reading frame 47
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC106 coiled-coil domain containing 106
CCDC186 coiled-coil domain containing 186
CD82 CD82 molecule
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CPA4 carboxypeptidase A4
CRYGC crystallin, gamma C
CTC1 CTS telomere maintenance complex component 1
CTSO cathepsin O
DCLRE1A DNA cross-link repair 1A
E2F8 E2F transcription factor 8
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGF epidermal growth factor
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM169A family with sequence similarity 169, member A
FAM206A family with sequence similarity 206, member A
FAM50B family with sequence similarity 50, member B
GDAP1 ganglioside induced differentiation associated protein 1
GLT8D2 glycosyltransferase 8 domain containing 2
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
HAUS6 HAUS augmin-like complex, subunit 6
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HLX H2.0-like homeobox
HOXA4 homeobox A4
HOXC13 homeobox C13
IFT81 intraflagellar transport 81
INF2 inverted formin, FH2 and WH2 domain containing
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA1549L KIAA1549-like
KIF16B kinesin family member 16B
KLF7 Kruppel-like factor 7 (ubiquitous)
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MBD5 methyl-CpG binding domain protein 5
MCM9 minichromosome maintenance complex component 9
MDN1 MDN1, midasin homolog (yeast)
METTL8 methyltransferase like 8
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MOB3B MOB kinase activator 3B
MRAS muscle RAS oncogene homolog
MRPL52 mitochondrial ribosomal protein L52
MYH15 myosin, heavy chain 15
NHLRC2 NHL repeat containing 2
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NPR3 natriuretic peptide receptor 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
ORC1 origin recognition complex, subunit 1
PARPBP PARP1 binding protein
PGP phosphoglycolate phosphatase
PHKG2 phosphorylase kinase, gamma 2 (testis)
POLI polymerase (DNA directed) iota
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RINT1 RAD50 interactor 1
RNF146 ring finger protein 146
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TUBB2B tubulin, beta 2B class IIb
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC119 unc-119 homolog (C. elegans)
WDR47 WD repeat domain 47
ZBTB48 zinc finger and BTB domain containing 48
ZNF442 zinc finger protein 442
ZNF573 zinc finger protein 573
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749