| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the CP-690334-01-4380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACACB | acetyl-CoA carboxylase beta |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APC2 | adenomatosis polyposis coli 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD177 | CD177 molecule |
| CD53 | CD53 molecule |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDHR2 | cadherin-related family member 2 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCA1 | chloride channel accessory 1 |
| CNTN1 | contactin 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCR1 | chemokine (C-X-C motif) receptor 1 |
| DDO | D-aspartate oxidase |
| DOCK6 | dedicator of cytokinesis 6 |
| DSC3 | desmocollin 3 |
| EBF2 | early B-cell factor 2 |
| EMC3 | ER membrane protein complex subunit 3 |
| FAM46C | family with sequence similarity 46, member C |
| FAM49A | family with sequence similarity 49, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FRMD1 | FERM domain containing 1 |
| FRZB | frizzled-related protein |
| GLS | glutaminase |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H3J | histone cluster 1, H3j |
| HIST2H2BE | histone cluster 2, H2be |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IFT54 | intraflagellar transport 54 |
| INSIG1 | insulin induced gene 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAK | male germ cell-associated kinase |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAP2 | microtubule-associated protein 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MST1 | macrophage stimulating 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NPFF | neuropeptide FF-amide peptide precursor |
| NUP54 | nucleoporin 54kDa |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PAX8 | paired box 8 |
| PCDH9 | protocadherin 9 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRKCI | protein kinase C, iota |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAI2 | retinoic acid induced 2 |
| RFPL3 | ret finger protein-like 3 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| SAPCD1 | suppressor APC domain containing 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIRT4 | sirtuin 4 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SMOX | spermine oxidase |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa |
| TP63 | tumor protein p63 |
| TRIM36 | tripartite motif containing 36 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| XAF1 | XIAP associated factor 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF10 | zinc finger protein 10 |
| ZNF264 | zinc finger protein 264 |
| ZNF467 | zinc finger protein 467 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACKR3 | atypical chemokine receptor 3 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMC4 | armadillo repeat containing 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CALML5 | calmodulin-like 5 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CBX2 | chromobox homolog 2 |
| CDH18 | cadherin 18, type 2 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLDN1 | claudin 1 |
| CNTFR | ciliary neurotrophic factor receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DEPDC5 | DEP domain containing 5 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| FAM212B | family with sequence similarity 212, member B |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOSL1 | FOS-like antigen 1 |
| FRK | fyn-related Src family tyrosine kinase |
| GAS2 | growth arrest-specific 2 |
| GATA4 | GATA binding protein 4 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1E | histone cluster 1, H1e |
| HOXC4 | homeobox C4 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL17RB | interleukin 17 receptor B |
| IL4R | interleukin 4 receptor |
| IQCC | IQ motif containing C |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0125 | KIAA0125 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KRT24 | keratin 24, type I |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LIF | leukemia inhibitory factor |
| LRRC49 | leucine rich repeat containing 49 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| NPTX1 | neuronal pentraxin I |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OCLM | oculomedin |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PCDH17 | protocadherin 17 |
| PCDHA6 | protocadherin alpha 6 |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POPDC3 | popeye domain containing 3 |
| POU3F2 | POU class 3 homeobox 2 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRAMEF11 | PRAME family member 11 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSCA | prostate stem cell antigen |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RFXAP | regulatory factor X-associated protein |
| RGS20 | regulator of G-protein signaling 20 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RND1 | Rho family GTPase 1 |
| RNF208 | ring finger protein 208 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SOAT2 | sterol O-acyltransferase 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TCP10 | t-complex 10 |
| TH | tyrosine hydroxylase |
| THBS3 | thrombospondin 3 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRAIP | TRAF interacting protein |
| TRIM68 | tripartite motif containing 68 |
| WDR76 | WD repeat domain 76 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF41 | zinc finger protein 41 |
| ZNF532 | zinc finger protein 532 |
| ZNF750 | zinc finger protein 750 |