CP-690334-01-4561 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the CP-690334-01-4561 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BCAS3 breast carcinoma amplified sequence 3
BTN3A2 butyrophilin, subfamily 3, member A2
C14ORF93 chromosome 14 open reading frame 93
CA5B carbonic anhydrase VB, mitochondrial
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC40 coiled-coil domain containing 40
CCDC71 coiled-coil domain containing 71
CCL11 chemokine (C-C motif) ligand 11
CDK20 cyclin-dependent kinase 20
CEP290 centrosomal protein 290kDa
CEP295 centrosomal protein 295kDa
CISH cytokine inducible SH2-containing protein
CNGA1 cyclic nucleotide gated channel alpha 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF21 chromosome X open reading frame 21
CYTH1 cytohesin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DPF1 D4, zinc and double PHD fingers family 1
E2F4 E2F transcription factor 4, p107/p130-binding
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC4 excision repair cross-complementation group 4
ESRRG estrogen-related receptor gamma
ETV6 ets variant 6
FBXL18 F-box and leucine-rich repeat protein 18
FGF18 fibroblast growth factor 18
FH fumarate hydratase
GPC3 glypican 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR19 G protein-coupled receptor 19
GRM8 glutamate receptor, metabotropic 8
HAP1 huntingtin-associated protein 1
HOXB2 homeobox B2
HPS6 Hermansky-Pudlak syndrome 6
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IDI2-AS1 IDI2 antisense RNA 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ING4 inhibitor of growth family, member 4
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCTD13 potassium channel tetramerization domain containing 13
KHSRP KH-type splicing regulatory protein
KIAA1109 KIAA1109
KIF13A kinesin family member 13A
KIF21B kinesin family member 21B
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LRP1 low density lipoprotein receptor-related protein 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBD2 methyl-CpG binding domain protein 2
MED16 mediator complex subunit 16
MMP3 matrix metallopeptidase 3
MUC3A mucin 3A, cell surface associated
NKTR natural killer cell triggering receptor
NOVA2 neuro-oncological ventral antigen 2
OASL 2'-5'-oligoadenylate synthetase-like
OCA2 oculocutaneous albinism II
OMG oligodendrocyte myelin glycoprotein
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBPL7 oxysterol binding protein-like 7
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PADI4 peptidyl arginine deiminase, type IV
PDLIM3 PDZ and LIM domain 3
PLCH1 phospholipase C, eta 1
PLSCR2 phospholipid scramblase 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKCQ protein kinase C, theta
PRPF18 pre-mRNA processing factor 18
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51B RAD51 paralog B
RBMS2 RNA binding motif, single stranded interacting protein 2
RCVRN recoverin
RND1 Rho family GTPase 1
RNF6 ring finger protein (C3H2C3 type) 6
RUFY3 RUN and FYVE domain containing 3
RUNX1 runt-related transcription factor 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIRAL2 SIR2 antiphage like 2
SLAMF7 SLAM family member 7
SLC16A4 solute carrier family 16, member 4
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK17A serine/threonine kinase 17a
STRN striatin, calmodulin binding protein
TBC1D30 TBC1 domain family, member 30
TBKBP1 TBK1 binding protein 1
THSD4 thrombospondin, type I, domain containing 4
TMPRSS4 transmembrane protease, serine 4
ZNF141 zinc finger protein 141

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AGMAT agmatine ureohydrolase (agmatinase)
AK5 adenylate kinase 5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARMCX4 armadillo repeat containing, X-linked 4
ATF3 activating transcription factor 3
BAAT bile acid CoA:amino acid N-acyltransferase
BAHD1 bromo adjacent homology domain containing 1
C3 complement component 3
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CD101 CD101 molecule
CEP131 centrosomal protein 131kDa
CHRDL1 chordin-like 1
CINP cyclin-dependent kinase 2 interacting protein
CPNE7 copine VII
CXCL3 chemokine (C-X-C motif) ligand 3
CXORF56 chromosome X open reading frame 56
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKE diacylglycerol kinase, epsilon 64kDa
EDC4 enhancer of mRNA decapping 4
EDIL3 EGF-like repeats and discoidin I-like domains 3
FADS2 fatty acid desaturase 2
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H1T histone cluster 1, H1t
HIST1H2BO histone cluster 1, H2bo
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI44L interferon-induced protein 44-like
IFT140 intraflagellar transport 140
IL12A interleukin 12A
IL7R interleukin 7 receptor
KIFC1 kinesin family member C1
KLF3 Kruppel-like factor 3 (basic)
KRT15 keratin 15, type I
LAX1 lymphocyte transmembrane adaptor 1
LINC00341 long intergenic non-protein coding RNA 341
LRRC61 leucine rich repeat containing 61
LYPLA2P1 lysophospholipase II pseudogene 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MGP matrix Gla protein
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MNMIP1 manchette microtubule inner protein 1
MT1M metallothionein 1M
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUD3 OTU deubiquitinase 3
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGPEP1 pyroglutamyl-peptidase I
PLA2G1B phospholipase A2, group IB (pancreas)
PLAC8 placenta-specific 8
PORCN porcupine homolog (Drosophila)
PRSS53 protease, serine, 53
RANBP17 RAN binding protein 17
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF122 ring finger protein 122
RNF31 ring finger protein 31
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETD1A SET domain containing 1A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPEG SPEG complex locus
ST5 suppression of tumorigenicity 5
STARD13 StAR-related lipid transfer (START) domain containing 13
TBX19 T-box 19
TEX40 testis expressed 40
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOR4A torsin family 4, member A
TSC22D4 TSC22 domain family, member 4
UNKL unkempt family zinc finger-like
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
USP19 ubiquitin specific peptidase 19
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
ZNF778 zinc finger protein 778