Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the CP-863187-7512 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACACB | acetyl-CoA carboxylase beta |
AGO4 | argonaute RISC catalytic component 4 |
AMBRA1 | autophagy/beclin-1 regulator 1 |
ANK1 | ankyrin 1, erythrocytic |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BMP4 | bone morphogenetic protein 4 |
BMP8A | bone morphogenetic protein 8a |
C19ORF60 | chromosome 19 open reading frame 60 |
C4ORF29 | chromosome 4 open reading frame 29 |
CA12 | carbonic anhydrase XII |
CD34 | CD34 molecule |
CIDEC | cell death-inducing DFFA-like effector c |
CORO1A | coronin, actin binding protein, 1A |
CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
CTIF | CBP80/20-dependent translation initiation factor |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
DGKA | diacylglycerol kinase, alpha 80kDa |
DMTN | dematin actin binding protein |
DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
EPN1 | epsin 1 |
EPS8L1 | EPS8-like 1 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
EXOSC2 | exosome component 2 |
FBRS | fibrosin |
FBXL15 | F-box and leucine-rich repeat protein 15 |
FGFR1 | fibroblast growth factor receptor 1 |
FSCN3 | fascin actin-bundling protein 3, testicular |
FUS | FUS RNA binding protein |
GAS7 | growth arrest-specific 7 |
GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
GRTP1 | growth hormone regulated TBC protein 1 |
HIST1H2BB | histone cluster 1, H2bb |
ICOSLG | inducible T-cell co-stimulator ligand |
IFNA17 | interferon, alpha 17 |
IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
ITGA7 | integrin, alpha 7 |
KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
KIAA0040 | KIAA0040 |
KIF5C | kinesin family member 5C |
KRT31 | keratin 31, type I |
LOC399491 | |
LOXL2 | lysyl oxidase-like 2 |
LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LYPD3 | LY6/PLAUR domain containing 3 |
MAP2K5 | mitogen-activated protein kinase kinase 5 |
MAP2K7 | mitogen-activated protein kinase kinase 7 |
MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
MECP2 | methyl CpG binding protein 2 |
MED25 | mediator complex subunit 25 |
MINK1 | misshapen-like kinase 1 |
MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
MOCS1 | molybdenum cofactor synthesis 1 |
MTMR12 | myotubularin related protein 12 |
MVD | mevalonate (diphospho) decarboxylase |
MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
NOTCH3 | notch 3 |
PDE12 | phosphodiesterase 12 |
PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
PGAP3 | post-GPI attachment to proteins 3 |
PI4KB | phosphatidylinositol 4-kinase, catalytic, beta |
PIDD1 | p53-induced death domain protein 1 |
PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha |
PRDX2 | peroxiredoxin 2 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RAD51B | RAD51 paralog B |
RANBP3 | RAN binding protein 3 |
RNF2 | ring finger protein 2 |
RPL10 | ribosomal protein L10 |
RPLP2 | ribosomal protein, large, P2 |
RSU1 | Ras suppressor protein 1 |
RUNX3 | runt-related transcription factor 3 |
SCARA3 | scavenger receptor class A, member 3 |
SFTPB | surfactant protein B |
SGK2 | serum/glucocorticoid regulated kinase 2 |
SHROOM2 | shroom family member 2 |
SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
SPN | sialophorin |
STOML1 | stomatin (EPB72)-like 1 |
SYK | spleen tyrosine kinase |
TADA2A | transcriptional adaptor 2A |
TLR6 | toll-like receptor 6 |
TMEM209 | transmembrane protein 209 |
TMPRSS5 | transmembrane protease, serine 5 |
TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
TUBA3C | tubulin, alpha 3c |
TXNRD2 | thioredoxin reductase 2 |
VASH1 | vasohibin 1 |
VIPR2 | vasoactive intestinal peptide receptor 2 |
WDR62 | WD repeat domain 62 |
WSB1 | WD repeat and SOCS box containing 1 |
ZBTB39 | zinc finger and BTB domain containing 39 |
ZDHHC14 | zinc finger, DHHC-type containing 14 |
ZNF205 | zinc finger protein 205 |
ZNF428 | zinc finger protein 428 |
ZNF862 | zinc finger protein 862 |
Symbol | Name |
---|---|
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ACOT13 | acyl-CoA thioesterase 13 |
ACVR1 | activin A receptor, type I |
ADAM15 | ADAM metallopeptidase domain 15 |
ADGRA3 | adhesion G protein-coupled receptor A3 |
AHR | aryl hydrocarbon receptor |
AIDA | axin interactor, dorsalization associated |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ANAPC10 | anaphase promoting complex subunit 10 |
ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
ARMCX5 | armadillo repeat containing, X-linked 5 |
ARSJ | arylsulfatase family, member J |
ATAD5 | ATPase family, AAA domain containing 5 |
BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
BPGM | 2,3-bisphosphoglycerate mutase |
C11ORF73 | chromosome 11 open reading frame 73 |
CDKN2AIP | CDKN2A interacting protein |
CHN1 | chimerin 1 |
CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
CIR1 | corepressor interacting with RBPJ, 1 |
CLDND1 | claudin domain containing 1 |
CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
CNN3 | calponin 3, acidic |
CTGF | connective tissue growth factor |
CYB5R4 | cytochrome b5 reductase 4 |
DCLRE1A | DNA cross-link repair 1A |
DCP2 | decapping mRNA 2 |
DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 |
DONSON | downstream neighbor of SON |
DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
ERCC8 | excision repair cross-complementation group 8 |
ERMP1 | endoplasmic reticulum metallopeptidase 1 |
ESM1 | endothelial cell-specific molecule 1 |
EXOC5 | exocyst complex component 5 |
FAM169A | family with sequence similarity 169, member A |
FAM188A | family with sequence similarity 188, member A |
FZD6 | frizzled class receptor 6 |
FZD8 | frizzled class receptor 8 |
GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
HIST1H2AE | histone cluster 1, H2ae |
HSPA4L | heat shock 70kDa protein 4-like |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IFI6 | interferon, alpha-inducible protein 6 |
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
KCTD9 | potassium channel tetramerization domain containing 9 |
KIF13A | kinesin family member 13A |
LMNB1 | lamin B1 |
METTL2B | methyltransferase like 2B |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MYOZ3 | myozenin 3 |
NCF2 | neutrophil cytosolic factor 2 |
NMD3 | NMD3 ribosome export adaptor |
NNT | nicotinamide nucleotide transhydrogenase |
NPY1R | neuropeptide Y receptor Y1 |
OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
PALMD | palmdelphin |
PANX1 | pannexin 1 |
PBK | PDZ binding kinase |
PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
PDZD2 | PDZ domain containing 2 |
PGM3 | phosphoglucomutase 3 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator |
PSAT1 | phosphoserine aminotransferase 1 |
RARS | arginyl-tRNA synthetase |
RIT1 | Ras-like without CAAX 1 |
RNF38 | ring finger protein 38 |
RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SEC24B | SEC24 family member B |
SELT | selenoprotein T |
SETD6 | SET domain containing 6 |
SIRT1 | sirtuin 1 |
SLCO1B3 | solute carrier organic anion transporter family, member 1B3 |
STAU2 | staufen double-stranded RNA binding protein 2 |
TBC1D12 | TBC1 domain family, member 12 |
TBCC | tubulin folding cofactor C |
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
TKFC | triokinase/FMN cyclase |
TMEM156 | transmembrane protein 156 |
TMEM230 | transmembrane protein 230 |
TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
TRAPPC2 | trafficking protein particle complex 2 |
TRPS1 | trichorhinophalangeal syndrome I |
TSPAN1 | tetraspanin 1 |
TTC17 | tetratricopeptide repeat domain 17 |
TTC33 | tetratricopeptide repeat domain 33 |
ZBTB10 | zinc finger and BTB domain containing 10 |
ZNF107 | zinc finger protein 107 |
ZNF124 | zinc finger protein 124 |
ZNF227 | zinc finger protein 227 |