CP-863187-7512 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the CP-863187-7512 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
AGO4 argonaute RISC catalytic component 4
AMBRA1 autophagy/beclin-1 regulator 1
ANK1 ankyrin 1, erythrocytic
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
BMP8A bone morphogenetic protein 8a
C19ORF60 chromosome 19 open reading frame 60
C4ORF29 chromosome 4 open reading frame 29
CA12 carbonic anhydrase XII
CD34 CD34 molecule
CIDEC cell death-inducing DFFA-like effector c
CORO1A coronin, actin binding protein, 1A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTIF CBP80/20-dependent translation initiation factor
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGKA diacylglycerol kinase, alpha 80kDa
DMTN dematin actin binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EPN1 epsin 1
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC2 exosome component 2
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FGFR1 fibroblast growth factor receptor 1
FSCN3 fascin actin-bundling protein 3, testicular
FUS FUS RNA binding protein
GAS7 growth arrest-specific 7
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GRTP1 growth hormone regulated TBC protein 1
HIST1H2BB histone cluster 1, H2bb
ICOSLG inducible T-cell co-stimulator ligand
IFNA17 interferon, alpha 17
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGA7 integrin, alpha 7
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0040 KIAA0040
KIF5C kinesin family member 5C
KRT31 keratin 31, type I
LOXL2 lysyl oxidase-like 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MECP2 methyl CpG binding protein 2
MED25 mediator complex subunit 25
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOCS1 molybdenum cofactor synthesis 1
MTMR12 myotubularin related protein 12
MVD mevalonate (diphospho) decarboxylase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NOTCH3 notch 3
PDE12 phosphodiesterase 12
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PGAP3 post-GPI attachment to proteins 3
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIDD1 p53-induced death domain protein 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PRDX2 peroxiredoxin 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51B RAD51 paralog B
RANBP3 RAN binding protein 3
RNF2 ring finger protein 2
RPL10 ribosomal protein L10
RPLP2 ribosomal protein, large, P2
RSU1 Ras suppressor protein 1
RUNX3 runt-related transcription factor 3
SCARA3 scavenger receptor class A, member 3
SFTPB surfactant protein B
SGK2 serum/glucocorticoid regulated kinase 2
SHROOM2 shroom family member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPN sialophorin
STOML1 stomatin (EPB72)-like 1
SYK spleen tyrosine kinase
TADA2A transcriptional adaptor 2A
TLR6 toll-like receptor 6
TMEM209 transmembrane protein 209
TMPRSS5 transmembrane protease, serine 5
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUBA3C tubulin, alpha 3c
TXNRD2 thioredoxin reductase 2
VASH1 vasohibin 1
VIPR2 vasoactive intestinal peptide receptor 2
WDR62 WD repeat domain 62
WSB1 WD repeat and SOCS box containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF205 zinc finger protein 205
ZNF428 zinc finger protein 428
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACOT13 acyl-CoA thioesterase 13
ACVR1 activin A receptor, type I
ADAM15 ADAM metallopeptidase domain 15
ADGRA3 adhesion G protein-coupled receptor A3
AHR aryl hydrocarbon receptor
AIDA axin interactor, dorsalization associated
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANAPC10 anaphase promoting complex subunit 10
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARMCX5 armadillo repeat containing, X-linked 5
ARSJ arylsulfatase family, member J
ATAD5 ATPase family, AAA domain containing 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BPGM 2,3-bisphosphoglycerate mutase
C11ORF73 chromosome 11 open reading frame 73
CDKN2AIP CDKN2A interacting protein
CHN1 chimerin 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CIR1 corepressor interacting with RBPJ, 1
CLDND1 claudin domain containing 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNN3 calponin 3, acidic
CTGF connective tissue growth factor
CYB5R4 cytochrome b5 reductase 4
DCLRE1A DNA cross-link repair 1A
DCP2 decapping mRNA 2
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DONSON downstream neighbor of SON
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERCC8 excision repair cross-complementation group 8
ERMP1 endoplasmic reticulum metallopeptidase 1
ESM1 endothelial cell-specific molecule 1
EXOC5 exocyst complex component 5
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FZD6 frizzled class receptor 6
FZD8 frizzled class receptor 8
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HIST1H2AE histone cluster 1, H2ae
HSPA4L heat shock 70kDa protein 4-like
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCTD9 potassium channel tetramerization domain containing 9
KIF13A kinesin family member 13A
LMNB1 lamin B1
METTL2B methyltransferase like 2B
MPDU1 mannose-P-dolichol utilization defect 1
MYOZ3 myozenin 3
NCF2 neutrophil cytosolic factor 2
NMD3 NMD3 ribosome export adaptor
NNT nicotinamide nucleotide transhydrogenase
NPY1R neuropeptide Y receptor Y1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PALMD palmdelphin
PANX1 pannexin 1
PBK PDZ binding kinase
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PDZD2 PDZ domain containing 2
PGM3 phosphoglucomutase 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PSAT1 phosphoserine aminotransferase 1
RARS arginyl-tRNA synthetase
RIT1 Ras-like without CAAX 1
RNF38 ring finger protein 38
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC24B SEC24 family member B
SELT selenoprotein T
SETD6 SET domain containing 6
SIRT1 sirtuin 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
STAU2 staufen double-stranded RNA binding protein 2
TBC1D12 TBC1 domain family, member 12
TBCC tubulin folding cofactor C
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TKFC triokinase/FMN cyclase
TMEM156 transmembrane protein 156
TMEM230 transmembrane protein 230
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAPPC2 trafficking protein particle complex 2
TRPS1 trichorhinophalangeal syndrome I
TSPAN1 tetraspanin 1
TTC17 tetratricopeptide repeat domain 17
TTC33 tetratricopeptide repeat domain 33
ZBTB10 zinc finger and BTB domain containing 10
ZNF107 zinc finger protein 107
ZNF124 zinc finger protein 124
ZNF227 zinc finger protein 227