CP-944629-7502 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the CP-944629-7502 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI1 abl-interactor 1
ACAN aggrecan
AGGF1 angiogenic factor with G patch and FHA domains 1
AKR1C2 aldo-keto reductase family 1, member C2
ALAD aminolevulinate dehydratase
ALPK3 alpha-kinase 3
APOL2 apolipoprotein L, 2
ARFRP1 ADP-ribosylation factor related protein 1
ARL14 ADP-ribosylation factor-like 14
ARL4D ADP-ribosylation factor-like 4D
ASB1 ankyrin repeat and SOCS box containing 1
ASTN2 astrotactin 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BBC3 BCL2 binding component 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CIB2 calcium and integrin binding family member 2
CLCN6 chloride channel, voltage-sensitive 6
COL7A1 collagen, type VII, alpha 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DTNA dystrobrevin, alpha
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FKBP8 FK506 binding protein 8, 38kDa
FOXC1 forkhead box C1
GAS7 growth arrest-specific 7
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
HDAC9 histone deacetylase 9
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXB6 homeobox B6
INADL InaD-like (Drosophila)
IQSEC2 IQ motif and Sec7 domain 2
KRIT1 KRIT1, ankyrin repeat containing
LAMC2 laminin, gamma 2
LIG3 ligase III, DNA, ATP-dependent
LMF1 lipase maturation factor 1
LRRC23 leucine rich repeat containing 23
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCTP1 multiple C2 domains, transmembrane 1
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MKL1 megakaryoblastic leukemia (translocation) 1
MST1 macrophage stimulating 1
MXRA8 matrix-remodelling associated 8
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXF2 nuclear RNA export factor 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAX9 paired box 9
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLIN2 perilipin 2
PLSCR4 phospholipid scramblase 4
PSD4 pleckstrin and Sec7 domain containing 4
RAB2A RAB2A, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF121 ring finger protein 121
RNF216 ring finger protein 216
ROR1 receptor tyrosine kinase-like orphan receptor 1
SCARB2 scavenger receptor class B, member 2
SERHL2 serine hydrolase-like 2
SETBP1 SET binding protein 1
SGSM3 small G protein signaling modulator 3
SH2D4A SH2 domain containing 4A
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC43A3 solute carrier family 43, member 3
SMG6 SMG6 nonsense mediated mRNA decay factor
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNHG20 small nucleolar RNA host gene 20
SNW1 SNW domain containing 1
STK17A serine/threonine kinase 17a
SYMPK symplekin
SYT17 synaptotagmin XVII
TAGLN3 transgelin 3
TDRD3 tudor domain containing 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM80 transmembrane protein 80
TNK2 tyrosine kinase, non-receptor, 2
TRAF2 TNF receptor-associated factor 2
TTLL5 tubulin tyrosine ligase-like family member 5
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VWA9 von Willebrand factor A domain containing 9
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APH1B APH1B gamma secretase subunit
ARHGAP10 Rho GTPase activating protein 10
ARRB2 arrestin, beta 2
ATXN8OS ATXN8 opposite strand (non-protein coding)
AVEN apoptosis, caspase activation inhibitor
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BEX1 brain expressed, X-linked 1
BFSP1 beaded filament structural protein 1, filensin
BRIX1 BRX1, biogenesis of ribosomes
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
CCNJ cyclin J
CCRL2 chemokine (C-C motif) receptor-like 2
CDH7 cadherin 7, type 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEC cell death-inducing DFFA-like effector c
CLDND1 claudin domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL3 chemokine (C-X-C motif) ligand 3
DAGLA diacylglycerol lipase, alpha
DIO3 deiodinase, iodothyronine, type III
DNAL4 dynein, axonemal, light chain 4
DPF3 D4, zinc and double PHD fingers, family 3
DUSP8 dual specificity phosphatase 8
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERMP1 endoplasmic reticulum metallopeptidase 1
EXO5 exonuclease 5
FAM186A family with sequence similarity 186, member A
FER fer (fps/fes related) tyrosine kinase
FKBP10 FK506 binding protein 10, 65 kDa
GDAP2 ganglioside induced differentiation associated protein 2
GEMIN8 gem (nuclear organelle) associated protein 8
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRPR gastrin-releasing peptide receptor
HDAC11 histone deacetylase 11
HIST1H2AG histone cluster 1, H2ag
HIST1H3B histone cluster 1, H3b
IFT54 intraflagellar transport 54
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL33 interleukin 33
INSIG2 insulin induced gene 2
KCNK13 potassium channel, two pore domain subfamily K, member 13
KIF3A kinesin family member 3A
KLHL36 kelch-like family member 36
LAMC3 laminin, gamma 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
MYBPC3 myosin binding protein C, cardiac
MYO1F myosin IF
MYRIP myosin VIIA and Rab interacting protein
NDP Norrie disease (pseudoglioma)
PADI1 peptidyl arginine deiminase, type I
PCDHA9 protocadherin alpha 9
PEX26 peroxisomal biogenesis factor 26
POLL polymerase (DNA directed), lambda
PRR4 proline rich 4 (lacrimal)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RND1 Rho family GTPase 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
STBD1 starch binding domain 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TASP1 taspase, threonine aspartase, 1
TBC1D19 TBC1 domain family, member 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THAP1 THAP domain containing, apoptosis associated protein 1
THOC6 THO complex 6
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TMEM8A transmembrane protein 8A
ULBP2 UL16 binding protein 2
USP6NL USP6 N-terminal like
UTF1 undifferentiated embryonic cell transcription factor 1
VGF VGF nerve growth factor inducible
WASF3 WAS protein family, member 3
WDR76 WD repeat domain 76
ZNF124 zinc finger protein 124
ZNF286A zinc finger protein 286A
ZNF33B zinc finger protein 33B