CP21R7_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description CP21R7 perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the CP21R7_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.104287
INTS6 integrator complex subunit 6 0.0837203
EXT1 exostosin glycosyltransferase 1 0.0835016
PHF3 PHD finger protein 3 0.0815705
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0807862
TSC22D1 TSC22 domain family, member 1 0.0727419
SQSTM1 sequestosome 1 0.0699126
ANXA2 annexin A2 0.0640615
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0535708
GCLC glutamate-cysteine ligase, catalytic subunit 0.0498089
NCOA7 nuclear receptor coactivator 7 0.0488544
SPTBN1 spectrin, beta, non-erythrocytic 1 0.048583
MUC20 mucin 20, cell surface associated 0.0479608
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.047846
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0476077
GOLGB1 golgin B1 0.0474959
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0463671
TRIO trio Rho guanine nucleotide exchange factor 0.045724
RRBP1 ribosome binding protein 1 0.044043
ZBTB20 zinc finger and BTB domain containing 20 0.0422841
EZR ezrin 0.0417374
TMC5 transmembrane channel-like 5 0.0416272
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.041439
KLF5 Kruppel-like factor 5 (intestinal) 0.0407509
ATP11A ATPase, class VI, type 11A 0.039856
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0385443
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0374451
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0374042
ERRFI1 ERBB receptor feedback inhibitor 1 0.0372777
POF1B premature ovarian failure, 1B 0.037221
CANX calnexin 0.0364929
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0364402
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0362078
RNF213 ring finger protein 213 0.0360371
APP amyloid beta (A4) precursor protein 0.0340599
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0329993
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0328261
TFRC transferrin receptor 0.0310415
MUC13 mucin 13, cell surface associated 0.0306628
TOX3 TOX high mobility group box family member 3 0.0302996
STAU1 staufen double-stranded RNA binding protein 1 0.0300154
BICRAL BICRA like chromatin remodeling complex associated protein 0.0299148
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0298911
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0294353
IGF1R insulin-like growth factor 1 receptor 0.0283544
AHI1 Abelson helper integration site 1 0.0282831
MYH9 myosin, heavy chain 9, non-muscle 0.0281845
DSCAM Down syndrome cell adhesion molecule 0.0280962
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.0279959
BAIAP2L1 BAI1-associated protein 2-like 1 0.0277138
ASPH aspartate beta-hydroxylase 0.0271979
MX1 MX dynamin-like GTPase 1 0.0271861
EPCAM epithelial cell adhesion molecule 0.027075
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0270584
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0270237
XAF1 XIAP associated factor 1 0.0269966
MAP7 microtubule-associated protein 7 0.0267943
HDLBP high density lipoprotein binding protein 0.0266841
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0265842
KDM3A lysine (K)-specific demethylase 3A 0.0264029
RIGI RNA sensor RIG-I 0.0262052
TM9SF2 transmembrane 9 superfamily member 2 0.0261421
CTNND1 catenin (cadherin-associated protein), delta 1 0.0260848
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.025656
IQGAP1 IQ motif containing GTPase activating protein 1 0.0255971
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0250903
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0244312
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0235949
ITGA1 integrin, alpha 1 0.0235896
SPATA13 spermatogenesis associated 13 0.0235738
PLSCR2 phospholipid scramblase 2 0.0235047
NIPBL Nipped-B homolog (Drosophila) 0.0231423
EPHB2 EPH receptor B2 0.0229518
MAML2 mastermind-like 2 (Drosophila) 0.022546
ITGA6 integrin, alpha 6 0.0225151
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0224248
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0223959
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0221409
TUFT1 tuftelin 1 0.0219915
CTBP2 C-terminal binding protein 2 0.0219808
TPR translocated promoter region, nuclear basket protein 0.0218963
ALCAM activated leukocyte cell adhesion molecule 0.02189
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0218025
SMAD3 SMAD family member 3 0.0216847
SDCBP2 syndecan binding protein (syntenin) 2 0.0216621
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0216037
GCC2 GRIP and coiled-coil domain containing 2 0.0214349
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0213631
TOP1 topoisomerase (DNA) I 0.0212531
PDLIM5 PDZ and LIM domain 5 0.0210345
ACTN4 actinin, alpha 4 0.0210318
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.0209458
UGDH UDP-glucose 6-dehydrogenase 0.020895
OARD1 O-acyl-ADP-ribose deacylase 1 0.0208693
PKM pyruvate kinase, muscle 0.0207934
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0207558
STRBP spermatid perinuclear RNA binding protein 0.0207441
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.020649
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0205092
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.02048

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0956821
ERBIN erbb2 interacting protein -0.0720444
MACC1 metastasis associated in colon cancer 1 -0.063242
B2M beta-2-microglobulin -0.0564494
NDRG1 N-myc downstream regulated 1 -0.042019
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0417299
RPS6 ribosomal protein S6 -0.0410642
IFI27 interferon, alpha-inducible protein 27 -0.0395554
C6ORF132 chromosome 6 open reading frame 132 -0.0381295
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.037826
PTBP3 polypyrimidine tract binding protein 3 -0.0355444
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0345826
LY6E lymphocyte antigen 6 complex, locus E -0.0332607
UBE2H ubiquitin-conjugating enzyme E2H -0.0326613
CCNL1 cyclin L1 -0.0326427
UBC ubiquitin C -0.0325849
EFHD2 EF-hand domain family, member D2 -0.0317347
TXNIP thioredoxin interacting protein -0.0311613
PTMA prothymosin, alpha -0.0309482
TMSB10 thymosin beta 10 -0.0304351
ARHGAP26 Rho GTPase activating protein 26 -0.0287697
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0282186
PTEN phosphatase and tensin homolog -0.027955
RPL35A ribosomal protein L35a -0.0265501
RBM25 RNA binding motif protein 25 -0.0264614
CTSD cathepsin D -0.0264182
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.0261538
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0254788
POTEF POTE ankyrin domain family, member F -0.0253304
RAB7A RAB7A, member RAS oncogene family -0.025253
MXD1 MAX dimerization protein 1 -0.0250343
ENO1 enolase 1, (alpha) -0.0242006
CLDN4 claudin 4 -0.0241938
HLA-B major histocompatibility complex, class I, B -0.0240819
KRT19 keratin 19, type I -0.0240769
SERF2 small EDRK-rich factor 2 -0.0236873
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.0236698
ENO2 enolase 2 (gamma, neuronal) -0.0232846
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0230272
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0226679
HLA-C major histocompatibility complex, class I, C -0.0223148
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0222525
LYZ lysozyme -0.0221026
S100A11 S100 calcium binding protein A11 -0.0220658
PLIN2 perilipin 2 -0.0219503
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0217548
MUC1 mucin 1, cell surface associated -0.0214455
RPS19 ribosomal protein S19 -0.0211964
ZNF148 zinc finger protein 148 -0.0211101
HLA-A major histocompatibility complex, class I, A -0.0210527
NAV1 neuron navigator 1 -0.0206501
DIAPH3 diaphanous-related formin 3 -0.0206308
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0201774
RPS23 ribosomal protein S23 -0.0199455
PDE8A phosphodiesterase 8A -0.0198967
S100A9 S100 calcium binding protein A9 -0.0198106
TRIM2 tripartite motif containing 2 -0.01964
ARL4C ADP-ribosylation factor-like 4C -0.019496
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0194405
ADAM10 ADAM metallopeptidase domain 10 -0.019261
RPS21 ribosomal protein S21 -0.019208
RPS8 ribosomal protein S8 -0.0191906
SETD5 SET domain containing 5 -0.0191543
FTH1 ferritin, heavy polypeptide 1 -0.0190714
RPS24 ribosomal protein S24 -0.0188988
RPS11 ribosomal protein S11 -0.018854
OCLN occludin -0.0188074
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.0187754
RSF1 remodeling and spacing factor 1 -0.0187558
S100A6 S100 calcium binding protein A6 -0.0183218
MKI67 marker of proliferation Ki-67 -0.0182002
BCL2L1 BCL2-like 1 -0.0181374
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.0181214
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0179687
KDM2A lysine (K)-specific demethylase 2A -0.0178805
MDK midkine (neurite growth-promoting factor 2) -0.0176481
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.017278
IGFBP3 insulin-like growth factor binding protein 3 -0.0172402
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0169236
TMEM165 transmembrane protein 165 -0.016811
CDKN2A cyclin-dependent kinase inhibitor 2A -0.01679
CALR calreticulin -0.0167416
VIM vimentin -0.0166748
INO80 INO80 complex subunit -0.0165711
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -0.0165521
RPL19 ribosomal protein L19 -0.0165465
BCLAF1 BCL2-associated transcription factor 1 -0.0164364
PNN pinin, desmosome associated protein -0.0164258
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0164252
NCEH1 neutral cholesterol ester hydrolase 1 -0.0163379
GLS2 glutaminase 2 (liver, mitochondrial) -0.0161968
RPL23 ribosomal protein L23 -0.0161766
RPLP1 ribosomal protein, large, P1 -0.0160249
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0158757
PFN1 profilin 1 -0.0158534
RSRC1 arginine/serine-rich coiled-coil 1 -0.0155587
IL6ST interleukin 6 signal transducer -0.0155544
KLHL24 kelch-like family member 24 -0.0155193
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0154993
LCN2 lipocalin 2 -0.0154559