| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the CP21R7_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.186879 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0936491 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0801882 |
| VIM | vimentin | 0.0604424 |
| CAPRIN2 | caprin family member 2 | 0.0565207 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0549103 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0502507 |
| POTEF | POTE ankyrin domain family, member F | 0.0497886 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473817 |
| FMNL2 | formin-like 2 | 0.0453817 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.044013 |
| TMSB10 | thymosin beta 10 | 0.0430488 |
| ENO1 | enolase 1, (alpha) | 0.0425816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0414591 |
| LDHA | lactate dehydrogenase A | 0.0364416 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0362835 |
| RPS4X | ribosomal protein S4, X-linked | 0.0361498 |
| MT1E | metallothionein 1E | 0.0348422 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.033924 |
| PKM | pyruvate kinase, muscle | 0.0317874 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0308843 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0303395 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0301641 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0295119 |
| DNER | delta/notch-like EGF repeat containing | 0.0273229 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0273228 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0268468 |
| PDE10A | phosphodiesterase 10A | 0.026593 |
| ANGPTL4 | angiopoietin-like 4 | 0.0262468 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0261282 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247968 |
| DST | dystonin | 0.0243978 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0236115 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231478 |
| SON | SON DNA binding protein | 0.022988 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0227391 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0226389 |
| B2M | beta-2-microglobulin | 0.022413 |
| RPL26 | ribosomal protein L26 | 0.0213285 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212709 |
| TP63 | tumor protein p63 | 0.0208233 |
| PLK2 | polo-like kinase 2 | 0.0206911 |
| RUNX1 | runt-related transcription factor 1 | 0.0203896 |
| EREG | epiregulin | 0.0198883 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0198339 |
| EGR1 | early growth response 1 | 0.0197818 |
| CD44 | CD44 molecule (Indian blood group) | 0.0195474 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0195165 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0194519 |
| CADM2 | cell adhesion molecule 2 | 0.0193578 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0191919 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.019069 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187513 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.018153 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0178205 |
| RPS19 | ribosomal protein S19 | 0.0176979 |
| VMP1 | vacuole membrane protein 1 | 0.0176002 |
| INTS6 | integrator complex subunit 6 | 0.0175779 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0175078 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173422 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0173317 |
| RPS3 | ribosomal protein S3 | 0.0171971 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0170897 |
| SQSTM1 | sequestosome 1 | 0.0170774 |
| RPS12 | ribosomal protein S12 | 0.0168974 |
| FTL | ferritin, light polypeptide | 0.0168467 |
| NEK10 | NIMA-related kinase 10 | 0.0167303 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0164991 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0164603 |
| RPL36 | ribosomal protein L36 | 0.01646 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0164437 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0156881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0156073 |
| RACK1 | receptor for activated C kinase 1 | 0.0155574 |
| JUN | jun proto-oncogene | 0.0153411 |
| HDAC9 | histone deacetylase 9 | 0.015284 |
| F2R | coagulation factor II (thrombin) receptor | 0.0152016 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0151529 |
| RPS18 | ribosomal protein S18 | 0.0150561 |
| VEGFC | vascular endothelial growth factor C | 0.0150347 |
| TPI1 | triosephosphate isomerase 1 | 0.0150319 |
| KLF6 | Kruppel-like factor 6 | 0.0149706 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0149308 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0147338 |
| MT1X | metallothionein 1X | 0.0145372 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0144589 |
| PRELID2 | PRELI domain containing 2 | 0.0144389 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0143469 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.013934 |
| ASPH | aspartate beta-hydroxylase | 0.0137834 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0137069 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0136194 |
| GOLGB1 | golgin B1 | 0.0130901 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0129529 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0128987 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0128791 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0128633 |
| DEK | DEK proto-oncogene | 0.0128627 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0128609 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0128297 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0692935 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0467856 |
| TXNRD1 | thioredoxin reductase 1 | -0.0388881 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0362298 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0274648 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0268233 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0228457 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0183086 |
| COL5A2 | collagen, type V, alpha 2 | -0.0172428 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0169785 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0167856 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0166983 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0165632 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0164145 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0162266 |
| TMEM123 | transmembrane protein 123 | -0.0158605 |
| RPS8 | ribosomal protein S8 | -0.0156179 |
| ERBIN | erbb2 interacting protein | -0.0155625 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0148812 |
| FNDC3B | fibronectin type III domain containing 3B | -0.014735 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0147212 |
| AHNAK | AHNAK nucleoprotein | -0.0141734 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0141244 |
| UBE3C | ubiquitin protein ligase E3C | -0.0139993 |
| FBXO11 | F-box protein 11 | -0.0139127 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0138648 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0138498 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0137194 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0135284 |
| RPL38 | ribosomal protein L38 | -0.0135228 |
| THOC2 | THO complex 2 | -0.0134324 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0131884 |
| RPL36A | ribosomal protein L36a | -0.0131362 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.013108 |
| RPL8 | ribosomal protein L8 | -0.0130506 |
| CEP95 | centrosomal protein 95kDa | -0.0129736 |
| RPL28 | ribosomal protein L28 | -0.0129351 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0128603 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0127342 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0126854 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0125387 |
| NF1 | neurofibromin 1 | -0.0124522 |
| RPS24 | ribosomal protein S24 | -0.0124323 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0122111 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0121763 |
| DIAPH3 | diaphanous-related formin 3 | -0.0121476 |
| RPS29 | ribosomal protein S29 | -0.0121009 |
| RPS21 | ribosomal protein S21 | -0.012 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0119641 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.011933 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0118858 |
| GLG1 | golgi glycoprotein 1 | -0.0118845 |
| RPLP2 | ribosomal protein, large, P2 | -0.0118523 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0118348 |
| SRPK2 | SRSF protein kinase 2 | -0.0116613 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0116531 |
| RPL35A | ribosomal protein L35a | -0.0115623 |
| RASA2 | RAS p21 protein activator 2 | -0.0114798 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0114631 |
| RPS16 | ribosomal protein S16 | -0.0114433 |
| RPL27A | ribosomal protein L27a | -0.0113732 |
| DENND5A | DENN/MADD domain containing 5A | -0.0113274 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0113184 |
| RAI1 | retinoic acid induced 1 | -0.0112214 |
| ETNK1 | ethanolamine kinase 1 | -0.0111868 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0111692 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.011062 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0108695 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0107518 |
| WDR45B | WD repeat domain 45B | -0.0106932 |
| MAP4 | microtubule-associated protein 4 | -0.0106799 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0106538 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.0105603 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0105516 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0105181 |
| FOXJ3 | forkhead box J3 | -0.0104525 |
| USP34 | ubiquitin specific peptidase 34 | -0.0104378 |
| CCDC91 | coiled-coil domain containing 91 | -0.0103906 |
| XPO1 | exportin 1 | -0.0103288 |
| XAF1 | XIAP associated factor 1 | -0.0103263 |
| ZNF207 | zinc finger protein 207 | -0.0102507 |
| FUS | FUS RNA binding protein | -0.0102407 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0101768 |
| SNX9 | sorting nexin 9 | -0.0101655 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0100847 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0100469 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0100358 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0100183 |
| UBC | ubiquitin C | -0.00994389 |
| GOLGA4 | golgin A4 | -0.00986152 |
| POM121 | POM121 transmembrane nucleoporin | -0.00985745 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.00981206 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0097873 |
| SETD5 | SET domain containing 5 | -0.00975481 |
| TP53 | tumor protein p53 | -0.00974304 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.0097257 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.00963801 |
| NBEAL1 | neurobeachin-like 1 | -0.00960777 |
| CLIC4 | chloride intracellular channel 4 | -0.00958786 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | -0.00952396 |
