| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the CP21R7_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.172295 |
| GRAMD1B | GRAM domain containing 1B | 0.0892997 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0860597 |
| SLTM | SAFB-like, transcription modulator | 0.0726688 |
| SEC61G | Sec61 gamma subunit | 0.0722328 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.06386 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0636291 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0631766 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0610654 |
| ASPH | aspartate beta-hydroxylase | 0.0600662 |
| LAMC2 | laminin, gamma 2 | 0.0559924 |
| STC1 | stanniocalcin 1 | 0.0532425 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0516871 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.049361 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0483155 |
| ENO1 | enolase 1, (alpha) | 0.0430815 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0427358 |
| ATP11A | ATPase, class VI, type 11A | 0.0425488 |
| CES1 | carboxylesterase 1 | 0.0424419 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0418513 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0380157 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037709 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0374951 |
| EGFR | epidermal growth factor receptor | 0.036308 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0357704 |
| CSNK1E | casein kinase 1, epsilon | 0.0351668 |
| HOMER1 | homer scaffolding protein 1 | 0.0328433 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0324792 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0316852 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0315456 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0313938 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0308547 |
| HSPA8 | heat shock 70kDa protein 8 | 0.030794 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301998 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0293973 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0285623 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0284675 |
| LAMA4 | laminin, alpha 4 | 0.028338 |
| SON | SON DNA binding protein | 0.0273108 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0270301 |
| DTNA | dystrobrevin, alpha | 0.0270227 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0267648 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265552 |
| OSMR | oncostatin M receptor | 0.0264914 |
| B2M | beta-2-microglobulin | 0.0261542 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0260793 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0257854 |
| MKI67 | marker of proliferation Ki-67 | 0.0257841 |
| RAD51B | RAD51 paralog B | 0.0255922 |
| AREG | amphiregulin | 0.0254842 |
| TPM3 | tropomyosin 3 | 0.0249859 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0247363 |
| PYGL | phosphorylase, glycogen, liver | 0.0247079 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0244722 |
| YBX3 | Y box binding protein 3 | 0.0242258 |
| ATP13A3 | ATPase type 13A3 | 0.0240406 |
| JMJD1C | jumonji domain containing 1C | 0.0240149 |
| FHL2 | four and a half LIM domains 2 | 0.0237973 |
| KYNU | kynureninase | 0.0237134 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0236293 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0235272 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0235249 |
| MSN | moesin | 0.0231227 |
| SMAD3 | SMAD family member 3 | 0.023056 |
| AGO2 | argonaute RISC catalytic component 2 | 0.022994 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0227314 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0226133 |
| RUNX1 | runt-related transcription factor 1 | 0.0222711 |
| GPATCH2L | G patch domain containing 2-like | 0.0218961 |
| RPLP1 | ribosomal protein, large, P1 | 0.02148 |
| BMP6 | bone morphogenetic protein 6 | 0.0214367 |
| VEGFC | vascular endothelial growth factor C | 0.0211985 |
| CHMP1B | charged multivesicular body protein 1B | 0.0210588 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0207429 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0202762 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.019875 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0197755 |
| RNF149 | ring finger protein 149 | 0.0196054 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0195373 |
| SP100 | SP100 nuclear antigen | 0.0195284 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0193639 |
| FOXP1 | forkhead box P1 | 0.0192978 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0191829 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0190946 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0189649 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0188139 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0187108 |
| FMNL2 | formin-like 2 | 0.0185228 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0185144 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0184992 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0183572 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0183493 |
| ACTN1 | actinin, alpha 1 | 0.0182366 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0181907 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0181634 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0177671 |
| MT1X | metallothionein 1X | 0.017552 |
| PKM | pyruvate kinase, muscle | 0.0174886 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0174194 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0173183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.124227 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.08592 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0804747 |
| TXNRD1 | thioredoxin reductase 1 | -0.0559242 |
| ANXA2 | annexin A2 | -0.0526059 |
| MYOF | myoferlin | -0.0499962 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0495128 |
| KRT7 | keratin 7, type II | -0.0445916 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0414525 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0394129 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0384238 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0381204 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.036943 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0368494 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0365139 |
| RPL37A | ribosomal protein L37a | -0.0353921 |
| TPD52 | tumor protein D52 | -0.0352875 |
| CCND1 | cyclin D1 | -0.0350602 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0347543 |
| PTMA | prothymosin, alpha | -0.0333093 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0331324 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331136 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0330017 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0326798 |
| SCEL | sciellin | -0.032584 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0317225 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0304951 |
| KRT8 | keratin 8, type II | -0.0298076 |
| ACTG1 | actin gamma 1 | -0.0297528 |
| RAB10 | RAB10, member RAS oncogene family | -0.0290316 |
| NDRG1 | N-myc downstream regulated 1 | -0.0280043 |
| H1-0 | H1.0 linker histone | -0.0273866 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0271773 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.025353 |
| KRT19 | keratin 19, type I | -0.0252921 |
| S100A10 | S100 calcium binding protein A10 | -0.0251314 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0241998 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0241508 |
| AHNAK | AHNAK nucleoprotein | -0.0241208 |
| PGK1 | phosphoglycerate kinase 1 | -0.0236207 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.023537 |
| TMSB10 | thymosin beta 10 | -0.0234281 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231547 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0229916 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0222424 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0221726 |
| MCU | mitochondrial calcium uniporter | -0.0218516 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0214738 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0212016 |
| CPE | carboxypeptidase E | -0.0211075 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0207824 |
| BMP7 | bone morphogenetic protein 7 | -0.020553 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0203341 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.019678 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0193766 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0192525 |
| FNIP1 | folliculin interacting protein 1 | -0.0192008 |
| PERP | PERP, TP53 apoptosis effector | -0.0191671 |
| TMEM165 | transmembrane protein 165 | -0.0191519 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0191173 |
| KRT18 | keratin 18, type I | -0.018842 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0183615 |
| MGAT4C | MGAT4 family, member C | -0.0183019 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0181154 |
| AGR2 | anterior gradient 2 | -0.0177157 |
| TES | testin LIM domain protein | -0.0174972 |
| HDLBP | high density lipoprotein binding protein | -0.0167743 |
| DENND5B | DENN/MADD domain containing 5B | -0.0167643 |
| GOLGA4 | golgin A4 | -0.0167002 |
| FLNB | filamin B, beta | -0.0165943 |
| RPL31 | ribosomal protein L31 | -0.0164632 |
| OGA | O-GlcNAcase | -0.0163711 |
| EZR | ezrin | -0.016348 |
| PRKCA | protein kinase C, alpha | -0.0161742 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0161379 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0160838 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0155521 |
| RASAL2 | RAS protein activator like 2 | -0.0154955 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0154662 |
| WDR45B | WD repeat domain 45B | -0.0154636 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0154014 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0153752 |
| JAK1 | Janus kinase 1 | -0.0153738 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0152641 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0152589 |
| CAV2 | caveolin 2 | -0.0152391 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0150576 |
| TNS3 | tensin 3 | -0.0149079 |
| GNAS | GNAS complex locus | -0.0148591 |
| RPS25 | ribosomal protein S25 | -0.0148254 |
| FBXO34 | F-box protein 34 | -0.0148147 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0147637 |
| WASF2 | WAS protein family, member 2 | -0.0147131 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0146498 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0146378 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.014632 |
| RPS12 | ribosomal protein S12 | -0.0145511 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0145385 |
| RPL35A | ribosomal protein L35a | -0.0144077 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0142306 |
