| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the CP21R7_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.0700585 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0597854 |
| AADAC | arylacetamide deacetylase | 0.0530728 |
| FAM20C | family with sequence similarity 20, member C | 0.0520333 |
| VEGFA | vascular endothelial growth factor A | 0.052007 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0504752 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.046516 |
| CDH13 | cadherin 13 | 0.0450647 |
| INTS6 | integrator complex subunit 6 | 0.0443774 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0440505 |
| IFI44L | interferon-induced protein 44-like | 0.043238 |
| PKM | pyruvate kinase, muscle | 0.0430126 |
| GLCCI1 | glucocorticoid induced 1 | 0.0405139 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0398448 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0392045 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0369736 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0369233 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0368002 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0366377 |
| TGFB1 | transforming growth factor, beta 1 | 0.0317309 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0316838 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0315761 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0287369 |
| SEPTIN9 | septin 9 | 0.0285394 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.027269 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0271492 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0271302 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0269386 |
| ASPH | aspartate beta-hydroxylase | 0.0262871 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.026182 |
| NRG1 | neuregulin 1 | 0.0255024 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.025122 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0248992 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0246951 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0237933 |
| MTSS1 | metastasis suppressor 1 | 0.0222627 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0220262 |
| MT2A | metallothionein 2A | 0.0219926 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0208679 |
| AVIL | advillin | 0.0208665 |
| WLS | wntless Wnt ligand secretion mediator | 0.0203587 |
| NLK | nemo-like kinase | 0.0198824 |
| EGFR | epidermal growth factor receptor | 0.0198466 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0197515 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0197323 |
| FBN1 | fibrillin 1 | 0.0195247 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0193873 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0193375 |
| TGM2 | transglutaminase 2 | 0.0189516 |
| LOXL2 | lysyl oxidase-like 2 | 0.0186883 |
| ATF7 | activating transcription factor 7 | 0.0185321 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0180983 |
| SHISA5 | shisa family member 5 | 0.0178091 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0175704 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0168951 |
| MX1 | MX dynamin-like GTPase 1 | 0.0168184 |
| NTN4 | netrin 4 | 0.0167609 |
| LDHA | lactate dehydrogenase A | 0.0166567 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0166339 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0165596 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0164648 |
| NAV1 | neuron navigator 1 | 0.0164243 |
| MYO10 | myosin X | 0.0162914 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0162822 |
| RNF213 | ring finger protein 213 | 0.0162701 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0161109 |
| RPS3 | ribosomal protein S3 | 0.0160933 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0160738 |
| RPL3 | ribosomal protein L3 | 0.0158784 |
| VMP1 | vacuole membrane protein 1 | 0.0158343 |
| HDAC9 | histone deacetylase 9 | 0.0157483 |
| ANXA10 | annexin A10 | 0.0157286 |
| NOTCH2 | notch 2 | 0.0156533 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0156513 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0155468 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0154376 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0151183 |
| RCOR1 | REST corepressor 1 | 0.0149383 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0147875 |
| ATXN1 | ataxin 1 | 0.0146928 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0145839 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0145483 |
| SP100 | SP100 nuclear antigen | 0.0143235 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0142556 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0142429 |
| GLIS3 | GLIS family zinc finger 3 | 0.0142271 |
| R3HDM2 | R3H domain containing 2 | 0.0142158 |
| RIGI | RNA sensor RIG-I | 0.0142147 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0140775 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0140576 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0140283 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0133384 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0132675 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0132491 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0131164 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.013048 |
| KSR1 | kinase suppressor of ras 1 | 0.0129737 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0129506 |
| EFNA5 | ephrin-A5 | 0.0129139 |
| ANGPTL4 | angiopoietin-like 4 | 0.0127307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.216769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182993 |
| TMSB10 | thymosin beta 10 | -0.094274 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0940156 |
| RBM39 | RNA binding motif protein 39 | -0.0862013 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0825582 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.082082 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.079629 |
| VIM | vimentin | -0.0754022 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0709694 |
| OSMR | oncostatin M receptor | -0.0703792 |
| CD44 | CD44 molecule (Indian blood group) | -0.0678007 |
| GOLGA4 | golgin A4 | -0.065856 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0646909 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0628286 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0609723 |
| PTMA | prothymosin, alpha | -0.0609374 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0574849 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0568211 |
| IER3 | immediate early response 3 | -0.0530596 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0522712 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0521206 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0515656 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0502333 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0476365 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0473814 |
| OGA | O-GlcNAcase | -0.0466161 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0457463 |
| USP34 | ubiquitin specific peptidase 34 | -0.0452051 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0445565 |
| S100A6 | S100 calcium binding protein A6 | -0.0436995 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0427941 |
| FAM13A | family with sequence similarity 13, member A | -0.0413928 |
| RPS21 | ribosomal protein S21 | -0.0407808 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0406841 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0395016 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0388979 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0384933 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0383685 |
| ATP13A3 | ATPase type 13A3 | -0.0380702 |
| NF1 | neurofibromin 1 | -0.0375497 |
| SPAG9 | sperm associated antigen 9 | -0.0370053 |
| FTL | ferritin, light polypeptide | -0.0369507 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0368785 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0362733 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0362291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0356956 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0356878 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354234 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0352065 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0351626 |
| USP3 | ubiquitin specific peptidase 3 | -0.0350095 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0346276 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0345814 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0345034 |
| SBF2 | SET binding factor 2 | -0.0342132 |
| GPC6 | glypican 6 | -0.0339794 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.033754 |
| JMJD1C | jumonji domain containing 1C | -0.0333603 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0332474 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0324633 |
| UBC | ubiquitin C | -0.0310593 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0309689 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.030927 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0308275 |
| TMSB4X | thymosin beta 4, X-linked | -0.0306744 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0305175 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0303468 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0302318 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0301797 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0293436 |
| CALU | calumenin | -0.0293342 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0291204 |
| GLG1 | golgi glycoprotein 1 | -0.0290532 |
| TXNRD1 | thioredoxin reductase 1 | -0.0286893 |
| CANX | calnexin | -0.0285804 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0281445 |
| WDR45B | WD repeat domain 45B | -0.0279593 |
| SETD5 | SET domain containing 5 | -0.0279079 |
| SRP54 | signal recognition particle 54kDa | -0.0278088 |
| RPL34 | ribosomal protein L34 | -0.0276575 |
| S100A10 | S100 calcium binding protein A10 | -0.0275882 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0275803 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0274297 |
| TMEM263 | transmembrane protein 263 | -0.027165 |
| RNF149 | ring finger protein 149 | -0.0270649 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0270011 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0268625 |
| SNX9 | sorting nexin 9 | -0.0268312 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0267708 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0267213 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0265037 |
| RPLP1 | ribosomal protein, large, P1 | -0.0264275 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0261747 |
| CD109 | CD109 molecule | -0.0260767 |
| FOXO3 | forkhead box O3 | -0.025989 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0259207 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0258791 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0258775 |
| SYAP1 | synapse associated protein 1 | -0.0253693 |
