| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the CP21R7_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.0699122 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0615615 |
| MYO1E | myosin IE | 0.0578939 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.052889 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0512667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0469577 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0469233 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0442116 |
| KYNU | kynureninase | 0.0421634 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0409234 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0408484 |
| PARD3 | par-3 family cell polarity regulator | 0.0361676 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0337915 |
| NEBL | nebulette | 0.0324777 |
| ANXA2 | annexin A2 | 0.0323188 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0318928 |
| RBM47 | RNA binding motif protein 47 | 0.030451 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0301076 |
| ASPH | aspartate beta-hydroxylase | 0.0299274 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0289893 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0288004 |
| EGFR | epidermal growth factor receptor | 0.028464 |
| TXNRD1 | thioredoxin reductase 1 | 0.027534 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0274941 |
| LAMC2 | laminin, gamma 2 | 0.0271864 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0270176 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0268512 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0263818 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0261365 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0260826 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0254581 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0244867 |
| RGS6 | regulator of G-protein signaling 6 | 0.0242091 |
| AHNAK | AHNAK nucleoprotein | 0.0235776 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0229838 |
| LAMA4 | laminin, alpha 4 | 0.0229747 |
| MXD1 | MAX dimerization protein 1 | 0.0227522 |
| SVIL | supervillin | 0.0227042 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.021988 |
| LMO7 | LIM domain 7 | 0.021544 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0213679 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.021332 |
| ANXA1 | annexin A1 | 0.0210709 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0203409 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0202829 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0201476 |
| RAB10 | RAB10, member RAS oncogene family | 0.0199913 |
| LDHA | lactate dehydrogenase A | 0.0198467 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0193692 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0192283 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0190451 |
| SMAD3 | SMAD family member 3 | 0.0190377 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0186082 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0183952 |
| MYOF | myoferlin | 0.0178976 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0177785 |
| DTNA | dystrobrevin, alpha | 0.0174283 |
| CLTC | clathrin, heavy chain (Hc) | 0.0174193 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0168643 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0168435 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0168376 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0168004 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0167253 |
| RIGI | RNA sensor RIG-I | 0.0167116 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0166556 |
| PRELID2 | PRELI domain containing 2 | 0.0166095 |
| CDCP1 | CUB domain containing protein 1 | 0.0164209 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0161819 |
| DSG2 | desmoglein 2 | 0.0159052 |
| KIF5B | kinesin family member 5B | 0.015791 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0156665 |
| CEP350 | centrosomal protein 350kDa | 0.0155913 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0155165 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0152796 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0151521 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0149843 |
| TSC22D2 | TSC22 domain family, member 2 | 0.014952 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0143651 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0143032 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0142018 |
| OGA | O-GlcNAcase | 0.0140189 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0138351 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0138345 |
| MUC13 | mucin 13, cell surface associated | 0.0137346 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0136683 |
| GOLGB1 | golgin B1 | 0.0136269 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0132952 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0132466 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0130914 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0130245 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0130042 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0130032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0127187 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0127125 |
| DSPP | dentin sialophosphoprotein | 0.012544 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0124984 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.012446 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0122855 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0122416 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0121906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0692683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0601959 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0481412 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0456098 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0377603 |
| RPL35A | ribosomal protein L35a | -0.0374269 |
| SPAG9 | sperm associated antigen 9 | -0.0371106 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0341358 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0331061 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0292724 |
| S100A6 | S100 calcium binding protein A6 | -0.028943 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0284563 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0278282 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0275424 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0266258 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261721 |
| RPL15 | ribosomal protein L15 | -0.0260887 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0259964 |
| POTEF | POTE ankyrin domain family, member F | -0.0257469 |
| RPS12 | ribosomal protein S12 | -0.0250865 |
| RPL28 | ribosomal protein L28 | -0.0248134 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.024809 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0245143 |
| RPS16 | ribosomal protein S16 | -0.0242935 |
| TPM4 | tropomyosin 4 | -0.0241113 |
| RPL12 | ribosomal protein L12 | -0.0237444 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.02308 |
| RPL37 | ribosomal protein L37 | -0.0229934 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0226144 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0225298 |
| RPS20 | ribosomal protein S20 | -0.022469 |
| MRTFA | myocardin related transcription factor A | -0.021796 |
| TMSB10 | thymosin beta 10 | -0.0215463 |
| RPL37A | ribosomal protein L37a | -0.0214785 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.021173 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.020866 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0201666 |
| RPS25 | ribosomal protein S25 | -0.0201012 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.019992 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0199788 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -0.0199166 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.019545 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0190763 |
| HLA-A | major histocompatibility complex, class I, A | -0.0189168 |
| NRG1 | neuregulin 1 | -0.0187689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0186333 |
| COG5 | component of oligomeric golgi complex 5 | -0.0184191 |
| RHOA | ras homolog family member A | -0.0180408 |
| RPS19 | ribosomal protein S19 | -0.0178431 |
| PAPOLA | poly(A) polymerase alpha | -0.0177082 |
| S100A9 | S100 calcium binding protein A9 | -0.0176817 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0172207 |
| THOC2 | THO complex 2 | -0.0172059 |
| STC1 | stanniocalcin 1 | -0.0169885 |
| UBC | ubiquitin C | -0.0167557 |
| GNAS | GNAS complex locus | -0.01667 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0166436 |
| RPLP2 | ribosomal protein, large, P2 | -0.0165926 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.016309 |
| COPA | coatomer protein complex, subunit alpha | -0.0161845 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0160572 |
| CUL3 | cullin 3 | -0.0157925 |
| SLMAP | sarcolemma associated protein | -0.0156507 |
| RPS6 | ribosomal protein S6 | -0.0154296 |
| RPL36 | ribosomal protein L36 | -0.0151105 |
| RPS8 | ribosomal protein S8 | -0.0149638 |
| VIM | vimentin | -0.0146771 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0146476 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0146463 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0143564 |
| RPS24 | ribosomal protein S24 | -0.0141772 |
| RPS27A | ribosomal protein S27a | -0.0138104 |
| FAT1 | FAT atypical cadherin 1 | -0.0137355 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137243 |
| CREBBP | CREB binding protein | -0.0136465 |
| RPL11 | ribosomal protein L11 | -0.0134414 |
| RNF145 | ring finger protein 145 | -0.0134142 |
| DST | dystonin | -0.0133698 |
| PTMA | prothymosin, alpha | -0.0131037 |
| STK17A | serine/threonine kinase 17a | -0.013097 |
| RUNX1 | runt-related transcription factor 1 | -0.0130171 |
| GPC6 | glypican 6 | -0.0129663 |
| PRKCA | protein kinase C, alpha | -0.012922 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0128449 |
| FRMD5 | FERM domain containing 5 | -0.0127844 |
| PTK2 | protein tyrosine kinase 2 | -0.0125261 |
| RPS3 | ribosomal protein S3 | -0.0125035 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0124748 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0123461 |
| FNDC3A | fibronectin type III domain containing 3A | -0.012333 |
| FTL | ferritin, light polypeptide | -0.0122109 |
| RPL26 | ribosomal protein L26 | -0.0120385 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.011926 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0117882 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0115846 |
| USP34 | ubiquitin specific peptidase 34 | -0.0114903 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0113943 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0112102 |
| RTN4 | reticulon 4 | -0.0112099 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.011202 |
