| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the CP21R7_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.0934988 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0835994 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.068038 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0634069 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0567969 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0549979 |
| CADM2 | cell adhesion molecule 2 | 0.05464 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0529395 |
| FOXP2 | forkhead box P2 | 0.0485043 |
| HDAC9 | histone deacetylase 9 | 0.0436503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0394158 |
| USP25 | ubiquitin specific peptidase 25 | 0.0381172 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0379671 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0367757 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.035893 |
| TSC22D2 | TSC22 domain family, member 2 | 0.035557 |
| CDC73 | cell division cycle 73 | 0.0346871 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0336703 |
| ZFHX4 | zinc finger homeobox 4 | 0.033113 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0330225 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0325274 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0309797 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0303648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299463 |
| ITGAV | integrin, alpha V | 0.0296782 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0287323 |
| OPHN1 | oligophrenin 1 | 0.0287063 |
| ZNF608 | zinc finger protein 608 | 0.0285952 |
| METAP2 | methionyl aminopeptidase 2 | 0.0283854 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0283465 |
| ANK2 | ankyrin 2, neuronal | 0.028196 |
| NFIB | nuclear factor I/B | 0.0275504 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0270811 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0260139 |
| MYO10 | myosin X | 0.025954 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0253233 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0250454 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0248361 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0245481 |
| YAP1 | Yes-associated protein 1 | 0.0241283 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0241147 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.023876 |
| PCDH9 | protocadherin 9 | 0.0235497 |
| HMGA2 | high mobility group AT-hook 2 | 0.0234419 |
| TFG | TRK-fused gene | 0.0234268 |
| NRXN1 | neurexin 1 | 0.0234093 |
| SHROOM3 | shroom family member 3 | 0.0229853 |
| BRD2 | bromodomain containing 2 | 0.022783 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0226498 |
| FAM171B | family with sequence similarity 171, member B | 0.0223926 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0222253 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0222055 |
| GLCCI1 | glucocorticoid induced 1 | 0.0221534 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0218212 |
| UBN2 | ubinuclein 2 | 0.0215598 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0213249 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0209262 |
| SON | SON DNA binding protein | 0.0206396 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0205714 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0205425 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0204547 |
| YBX1 | Y box binding protein 1 | 0.0203167 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0201537 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0201279 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0199568 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0199493 |
| CCNYL1 | cyclin Y-like 1 | 0.0199474 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0197838 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0197428 |
| NHSL1 | NHS-like 1 | 0.0196481 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.019629 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0194302 |
| RNF145 | ring finger protein 145 | 0.0193506 |
| SUGT1 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 0.0193479 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0192234 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0192189 |
| CTBP2 | C-terminal binding protein 2 | 0.0191684 |
| FRYL | FRY-like | 0.0191652 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0191482 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0189724 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.018922 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0189017 |
| TPM3 | tropomyosin 3 | 0.0188058 |
| GPC4 | glypican 4 | 0.0187653 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0187412 |
| DPYD | dihydropyrimidine dehydrogenase | 0.018727 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0185733 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0185271 |
| TOP1 | topoisomerase (DNA) I | 0.0185101 |
| RAB10 | RAB10, member RAS oncogene family | 0.0185032 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183826 |
| UTRN | utrophin | 0.0182908 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.018097 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0180622 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0180389 |
| RREB1 | ras responsive element binding protein 1 | 0.0179392 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0178915 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0177666 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0176998 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0175521 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187661 |
| VIM | vimentin | -0.143021 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.130905 |
| PTMA | prothymosin, alpha | -0.0876799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0787622 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0663097 |
| COL1A2 | collagen, type I, alpha 2 | -0.0636526 |
| GPC3 | glypican 3 | -0.0519954 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0503499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0475055 |
| CALR | calreticulin | -0.0468394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0462223 |
| RFPL4B | ret finger protein-like 4B | -0.0449495 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0443934 |
| RPS8 | ribosomal protein S8 | -0.0439734 |
| NTM | neurotrimin | -0.0429934 |
| RAI1 | retinoic acid induced 1 | -0.0426137 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0425259 |
| RPLP0 | ribosomal protein, large, P0 | -0.0409972 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0400701 |
| RPS16 | ribosomal protein S16 | -0.0394684 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.03917 |
| MAP4 | microtubule-associated protein 4 | -0.0381196 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0375934 |
| COL3A1 | collagen, type III, alpha 1 | -0.037553 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0359391 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0357589 |
| RPL36A | ribosomal protein L36a | -0.0353245 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347279 |
| MEIS2 | Meis homeobox 2 | -0.0346046 |
| GNAS | GNAS complex locus | -0.0334118 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0324155 |
| RPS12 | ribosomal protein S12 | -0.0321087 |
| NRG1 | neuregulin 1 | -0.031975 |
| LYST | lysosomal trafficking regulator | -0.0305811 |
| PHIP | pleckstrin homology domain interacting protein | -0.0298734 |
| SNX6 | sorting nexin 6 | -0.0296386 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0296235 |
| MTF2 | metal response element binding transcription factor 2 | -0.0294737 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0290387 |
| PGK1 | phosphoglycerate kinase 1 | -0.0286127 |
| ACTG1 | actin gamma 1 | -0.0283482 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0283096 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0277468 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0276676 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276262 |
| PLPP1 | phospholipid phosphatase 1 | -0.0275872 |
| THOC2 | THO complex 2 | -0.0269994 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0267699 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0263842 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0262982 |
| EAPP | E2F-associated phosphoprotein | -0.0260384 |
| LPIN2 | lipin 2 | -0.0259717 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0256134 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0249097 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0246809 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0246265 |
| RPS6 | ribosomal protein S6 | -0.0244354 |
| EXOC1 | exocyst complex component 1 | -0.0244024 |
| UPP1 | uridine phosphorylase 1 | -0.0238742 |
| CALU | calumenin | -0.023566 |
| PDS5A | PDS5 cohesin associated factor A | -0.0232937 |
| TMSB4X | thymosin beta 4, X-linked | -0.0226397 |
| RPS27A | ribosomal protein S27a | -0.0225959 |
| CAVIN1 | caveolae associated protein 1 | -0.0225791 |
| PHF21A | PHD finger protein 21A | -0.0225216 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.022367 |
| RPL35A | ribosomal protein L35a | -0.0223507 |
| B2M | beta-2-microglobulin | -0.0223002 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0221103 |
| LMBR1 | limb development membrane protein 1 | -0.0217871 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0217327 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.021609 |
| COG5 | component of oligomeric golgi complex 5 | -0.0214136 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0213873 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0211245 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0211213 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0209611 |
| RPS24 | ribosomal protein S24 | -0.020956 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0208382 |
| RPS25 | ribosomal protein S25 | -0.0207553 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0207477 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.020739 |
| DMD | dystrophin | -0.0207022 |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | -0.0207013 |
| TPM4 | tropomyosin 4 | -0.0206837 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0205818 |
| TPR | translocated promoter region, nuclear basket protein | -0.0205372 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0205102 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0204046 |
| UBC | ubiquitin C | -0.0203132 |
| RPS19 | ribosomal protein S19 | -0.0202974 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0201515 |
| SFTPA2 | surfactant protein A2 | -0.0201136 |
| HM13 | histocompatibility (minor) 13 | -0.0197809 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0197157 |
| TPX2 | TPX2, microtubule-associated | -0.0195981 |
| EMP1 | epithelial membrane protein 1 | -0.0195938 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0194995 |
| ATXN1 | ataxin 1 | -0.0192116 |
