| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the CP21R7_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0879441 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0548692 |
| BMP10 | bone morphogenetic protein 10 | 0.0505477 |
| MKI67 | marker of proliferation Ki-67 | 0.0452964 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0433758 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0352196 |
| CENPF | centromere protein F, 350/400kDa | 0.0338099 |
| HDAC9 | histone deacetylase 9 | 0.0335972 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0324817 |
| HJURP | Holliday junction recognition protein | 0.0292661 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0283415 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0271973 |
| GLI3 | GLI family zinc finger 3 | 0.0271114 |
| AEBP2 | AE binding protein 2 | 0.0270557 |
| ANXA1 | annexin A1 | 0.0251031 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0238634 |
| DIAPH3 | diaphanous-related formin 3 | 0.0231816 |
| PDE7B | phosphodiesterase 7B | 0.0226222 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221297 |
| POTEF | POTE ankyrin domain family, member F | 0.0221244 |
| INTS6 | integrator complex subunit 6 | 0.0212247 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0204416 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0202235 |
| SMC4 | structural maintenance of chromosomes 4 | 0.020189 |
| ANLN | anillin, actin binding protein | 0.0198951 |
| BMP2K | BMP2 inducible kinase | 0.0191232 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.018754 |
| RPL3 | ribosomal protein L3 | 0.0187535 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0184378 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0183846 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0183842 |
| TXK | TXK tyrosine kinase | 0.0178723 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0175807 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.017333 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0169347 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0168783 |
| CPNE2 | copine II | 0.0163532 |
| CEP295 | centrosomal protein 295kDa | 0.0159015 |
| GSE1 | Gse1 coiled-coil protein | 0.015873 |
| DNAAF3 | dynein, axonemal, assembly factor 3 | 0.0150819 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0149187 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0147317 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0147173 |
| FMNL2 | formin-like 2 | 0.0146656 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0146311 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0145283 |
| ITGA10 | integrin, alpha 10 | 0.0144407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0143679 |
| PTMS | parathymosin | 0.0140725 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0139975 |
| TPX2 | TPX2, microtubule-associated | 0.0138044 |
| UTRN | utrophin | 0.013759 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0137555 |
| CCDC18 | coiled-coil domain containing 18 | 0.0136649 |
| RCOR1 | REST corepressor 1 | 0.0135756 |
| SGMS2 | sphingomyelin synthase 2 | 0.0134642 |
| VRK1 | vaccinia related kinase 1 | 0.013374 |
| CENPE | centromere protein E, 312kDa | 0.0133469 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | 0.0133041 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0132186 |
| FANCI | Fanconi anemia, complementation group I | 0.0131536 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0128952 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0128246 |
| SON | SON DNA binding protein | 0.0127747 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0126404 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0125844 |
| BRD4 | bromodomain containing 4 | 0.0125194 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0125035 |
| CCNH | cyclin H | 0.0123929 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0121987 |
| PRSS23 | protease, serine, 23 | 0.0121502 |
| NOTCH2 | notch 2 | 0.0121151 |
| HDGF | hepatoma-derived growth factor | 0.0120884 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0120285 |
| EFL1 | elongation factor like GTPase 1 | 0.0119981 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0119546 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0119187 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0118502 |
| PBK | PDZ binding kinase | 0.0118234 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0117451 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0117307 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0115805 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0115516 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0114923 |
| MYEOV | myeloma overexpressed | 0.0114068 |
| BSG | basigin (Ok blood group) | 0.0113592 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0112799 |
| CNTLN | centlein, centrosomal protein | 0.0112625 |
| ZNF438 | zinc finger protein 438 | 0.0112532 |
| CUX1 | cut-like homeobox 1 | 0.0112075 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0111986 |
| PSPC1 | paraspeckle component 1 | 0.0111646 |
| RPL21 | ribosomal protein L21 | 0.0111571 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.0111521 |
| SETD2 | SET domain containing 2 | 0.01109 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0110458 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.01103 |
| NMD3 | NMD3 ribosome export adaptor | 0.0109521 |
| KNL1 | kinetochore scaffold 1 | 0.01095 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0109463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.172119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164441 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156032 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0953102 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0920722 |
| GOLGA4 | golgin A4 | -0.0736966 |
| FLNB | filamin B, beta | -0.0722025 |
| TMSB4X | thymosin beta 4, X-linked | -0.0700745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0694748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0692824 |
| S100A6 | S100 calcium binding protein A6 | -0.064069 |
| RBM39 | RNA binding motif protein 39 | -0.0596481 |
| NF1 | neurofibromin 1 | -0.0574608 |
| AHNAK | AHNAK nucleoprotein | -0.055069 |
| RPLP1 | ribosomal protein, large, P1 | -0.0545584 |
| RPL35A | ribosomal protein L35a | -0.0526365 |
| RPL13A | ribosomal protein L13a | -0.052422 |
| FBXO11 | F-box protein 11 | -0.0522327 |
| RPS6 | ribosomal protein S6 | -0.0520745 |
| RTN4 | reticulon 4 | -0.0517789 |
| ANK2 | ankyrin 2, neuronal | -0.0504974 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0501595 |
| ACTG1 | actin gamma 1 | -0.0478843 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0468879 |
| TXNRD1 | thioredoxin reductase 1 | -0.0464456 |
| ZNF292 | zinc finger protein 292 | -0.0454336 |
| PGK1 | phosphoglycerate kinase 1 | -0.0452051 |
| RPL11 | ribosomal protein L11 | -0.0447527 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.044113 |
| TMSB10 | thymosin beta 10 | -0.0429104 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0415591 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0415286 |
| RPS19 | ribosomal protein S19 | -0.0405875 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0405336 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0403791 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.039152 |
| RPL36 | ribosomal protein L36 | -0.0383502 |
| RPS25 | ribosomal protein S25 | -0.0380902 |
| PYGB | phosphorylase, glycogen; brain | -0.0377034 |
| RPS13 | ribosomal protein S13 | -0.0373061 |
| RPL31 | ribosomal protein L31 | -0.0372002 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0368091 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0349632 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0348721 |
| RPS27A | ribosomal protein S27a | -0.0346499 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0345202 |
| RPL27A | ribosomal protein L27a | -0.0344124 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0343762 |
| RPL37A | ribosomal protein L37a | -0.0342995 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0336181 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333327 |
| RPL26 | ribosomal protein L26 | -0.0327637 |
| RPL9 | ribosomal protein L9 | -0.0326498 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0326031 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0324049 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0320961 |
| RPS24 | ribosomal protein S24 | -0.0319818 |
| CDC73 | cell division cycle 73 | -0.031843 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0317942 |
| TMEM41B | transmembrane protein 41B | -0.0317222 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.03153 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0310853 |
| HDLBP | high density lipoprotein binding protein | -0.031028 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0308105 |
| QKI | QKI, KH domain containing, RNA binding | -0.0306304 |
| RPL19 | ribosomal protein L19 | -0.0306085 |
| RPL34 | ribosomal protein L34 | -0.0303514 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0297468 |
| RPLP0 | ribosomal protein, large, P0 | -0.029486 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0292857 |
| RPS12 | ribosomal protein S12 | -0.0289791 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0285852 |
| EXOC6B | exocyst complex component 6B | -0.0285035 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0284832 |
| TBC1D22A | TBC1 domain family, member 22A | -0.028397 |
| RPS20 | ribosomal protein S20 | -0.0283799 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0280939 |
| TJP1 | tight junction protein 1 | -0.0280131 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0277615 |
| TUT4 | terminal uridylyl transferase 4 | -0.0276223 |
| NCKAP1 | NCK-associated protein 1 | -0.0275419 |
| CALR | calreticulin | -0.0275071 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0274886 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0273709 |
| JMJD1C | jumonji domain containing 1C | -0.0272402 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0269722 |
| GNAS | GNAS complex locus | -0.026837 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0266079 |
| RPL12 | ribosomal protein L12 | -0.0265766 |
| FUS | FUS RNA binding protein | -0.0265334 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264526 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0262138 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0261896 |
| CCNL1 | cyclin L1 | -0.0261671 |
| GPHN | gephyrin | -0.0261317 |
| RPS27 | ribosomal protein S27 | -0.0259426 |
| RBM25 | RNA binding motif protein 25 | -0.0258711 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0258249 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0255164 |
| RPS21 | ribosomal protein S21 | -0.0255134 |