| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | CP21R7 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the CP21R7_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.119509 |
| MT2A | metallothionein 2A | 0.10407 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0819135 |
| VEGFA | vascular endothelial growth factor A | 0.0715757 |
| IL6 | interleukin 6 | 0.070332 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0587944 |
| NDRG1 | N-myc downstream regulated 1 | 0.0581046 |
| FAM13A | family with sequence similarity 13, member A | 0.0533724 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0493606 |
| ARRDC3 | arrestin domain containing 3 | 0.0449131 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0439977 |
| MAP1B | microtubule-associated protein 1B | 0.0432178 |
| PKM | pyruvate kinase, muscle | 0.0422384 |
| KYNU | kynureninase | 0.0419256 |
| FNDC3B | fibronectin type III domain containing 3B | 0.041842 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0411316 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0408812 |
| LDHA | lactate dehydrogenase A | 0.0391106 |
| ZNF395 | zinc finger protein 395 | 0.0390443 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0385931 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0382895 |
| STC1 | stanniocalcin 1 | 0.0382064 |
| MATR3 | matrin 3 | 0.0365219 |
| MSN | moesin | 0.0358745 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0338908 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0338854 |
| CD44 | CD44 molecule (Indian blood group) | 0.0330887 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0318701 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0311823 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0311467 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.030342 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0302332 |
| FOSL1 | FOS-like antigen 1 | 0.0289138 |
| RND3 | Rho family GTPase 3 | 0.0272046 |
| ZNF292 | zinc finger protein 292 | 0.0267538 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0263591 |
| GSE1 | Gse1 coiled-coil protein | 0.0259146 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0256419 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0245931 |
| RPS4X | ribosomal protein S4, X-linked | 0.0244156 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0244013 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0243026 |
| RIOK3 | RIO kinase 3 | 0.0242793 |
| WDR43 | WD repeat domain 43 | 0.0240646 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0239508 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0234657 |
| TLN1 | talin 1 | 0.0232502 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0231502 |
| CCDC14 | coiled-coil domain containing 14 | 0.0231299 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0228633 |
| TANK | TRAF family member-associated NFKB activator | 0.0228098 |
| METTL15 | methyltransferase like 15 | 0.0224622 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0224249 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0224046 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0223645 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0220103 |
| ECE1 | endothelin converting enzyme 1 | 0.0220029 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.022002 |
| PCBP2 | poly(rC) binding protein 2 | 0.0219548 |
| SEM1 | SEM1 26S proteasome subunit | 0.0215893 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0214956 |
| NBAS | neuroblastoma amplified sequence | 0.0212667 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0212067 |
| MYO10 | myosin X | 0.0212013 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.020897 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0208925 |
| PRELID2 | PRELI domain containing 2 | 0.0208431 |
| ZNF451 | zinc finger protein 451 | 0.0206174 |
| BMERB1 | bMERB domain containing 1 | 0.0206098 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0205623 |
| L1CAM | L1 cell adhesion molecule | 0.0205472 |
| POTEF | POTE ankyrin domain family, member F | 0.0203985 |
| RNF24 | ring finger protein 24 | 0.0203985 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.020362 |
| RPL3 | ribosomal protein L3 | 0.0203144 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0202946 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0201423 |
| CDC27 | cell division cycle 27 | 0.0200628 |
| BRD2 | bromodomain containing 2 | 0.020054 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0197407 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0196926 |
| ANXA5 | annexin A5 | 0.0196725 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0196513 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0196042 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0194507 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.019434 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0193999 |
| ZNF148 | zinc finger protein 148 | 0.019322 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0190363 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0190105 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.018885 |
| TNS3 | tensin 3 | 0.0188057 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0187854 |
| VEGFC | vascular endothelial growth factor C | 0.0187462 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0186138 |
| OAF | OAF homolog (Drosophila) | 0.0185191 |
| RAB8B | RAB8B, member RAS oncogene family | 0.018505 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0184256 |
| TTYH3 | tweety family member 3 | 0.0183096 |
| CBX3 | chromobox homolog 3 | 0.0182349 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.164132 |
| COL1A1 | collagen, type I, alpha 1 | -0.161683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126133 |
| COL1A2 | collagen, type I, alpha 2 | -0.109513 |
| HLA-B | major histocompatibility complex, class I, B | -0.105719 |
| LOX | lysyl oxidase | -0.0856499 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0856392 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0756822 |
| HLA-C | major histocompatibility complex, class I, C | -0.0642175 |
| FN1 | fibronectin 1 | -0.0626274 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0597465 |
| VIM | vimentin | -0.0559347 |
| CAVIN1 | caveolae associated protein 1 | -0.055514 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0545727 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0522568 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0486737 |
| TMSB10 | thymosin beta 10 | -0.0485602 |
| TPM4 | tropomyosin 4 | -0.0481293 |
| COL3A1 | collagen, type III, alpha 1 | -0.0470106 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0441049 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0436892 |
| CALU | calumenin | -0.041889 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0411133 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0390383 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0388712 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0367868 |
| CALR | calreticulin | -0.0362512 |
| B2M | beta-2-microglobulin | -0.0359088 |
| CDH13 | cadherin 13 | -0.0354556 |
| AHNAK | AHNAK nucleoprotein | -0.0341846 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0324997 |
| GNAS | GNAS complex locus | -0.0320917 |
| JMJD1C | jumonji domain containing 1C | -0.0320325 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0318831 |
| PTMA | prothymosin, alpha | -0.0313897 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0307822 |
| TMEM263 | transmembrane protein 263 | -0.0307722 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0304374 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0299256 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0298966 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0296858 |
| RRBP1 | ribosome binding protein 1 | -0.0296333 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0287889 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0276913 |
| RPL34 | ribosomal protein L34 | -0.0276359 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0272894 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.027255 |
| AUTS2 | autism susceptibility candidate 2 | -0.0272034 |
| S100A10 | S100 calcium binding protein A10 | -0.0270821 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0265964 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0263882 |
| SIL1 | SIL1 nucleotide exchange factor | -0.0263454 |
| PGK1 | phosphoglycerate kinase 1 | -0.0259875 |
| RPS13 | ribosomal protein S13 | -0.0259544 |
| TNNC1 | troponin C type 1 (slow) | -0.0257219 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0255434 |
| CDK12 | cyclin-dependent kinase 12 | -0.0252775 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0251634 |
| RPS23 | ribosomal protein S23 | -0.0246336 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0245759 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0245375 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0241425 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0240398 |
| TMEM41B | transmembrane protein 41B | -0.0240357 |
| PLCB4 | phospholipase C, beta 4 | -0.0239775 |
| EGFR | epidermal growth factor receptor | -0.0238956 |
| NUP98 | nucleoporin 98kDa | -0.0237448 |
| RPS29 | ribosomal protein S29 | -0.0233462 |
| OXR1 | oxidation resistance 1 | -0.0231585 |
| SEC24D | SEC24 family member D | -0.0231208 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0230441 |
| DSTN | destrin (actin depolymerizing factor) | -0.0228707 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0228382 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0228082 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0227337 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0225892 |
| RPS24 | ribosomal protein S24 | -0.0225805 |
| CDK6 | cyclin-dependent kinase 6 | -0.0224728 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0223854 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0220594 |
| TNPO1 | transportin 1 | -0.022034 |
| KIF1B | kinesin family member 1B | -0.0216224 |
| ERBIN | erbb2 interacting protein | -0.021544 |
| CANX | calnexin | -0.0214733 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0213315 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0212285 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0212023 |
| ATG7 | autophagy related 7 | -0.0211306 |
| PRKCA | protein kinase C, alpha | -0.0209706 |
| CTSB | cathepsin B | -0.0208908 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0207727 |
| FBXO11 | F-box protein 11 | -0.0205097 |
| FLOT1 | flotillin 1 | -0.0204821 |
| DMXL1 | Dmx-like 1 | -0.02043 |
| RPL37A | ribosomal protein L37a | -0.020366 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0202793 |
| GPR173 | G protein-coupled receptor 173 | -0.0200623 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0199628 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0199222 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0197969 |
