CP466722 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

64 kinases inhibited by the CP466722 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
ACVR1 activin A receptor, type I 1.35325
NEK6 NIMA-related kinase 6 1.35325
CDKL5 cyclin-dependent kinase-like 5 1.34449
BMPR1B bone morphogenetic protein receptor, type IB 1.34449
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.34449
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.33582
AURKB aurora kinase B 1.33582
HIPK1 homeodomain interacting protein kinase 1 1.31878
MAPK15 mitogen-activated protein kinase 15 1.31878
CLK1 CDC-like kinase 1 1.31878
HIPK2 homeodomain interacting protein kinase 2 1.3104
NEK7 NIMA-related kinase 7 1.25436
BMPR1A bone morphogenetic protein receptor, type IA 1.25436
STK17A serine/threonine kinase 17a 1.23916
CSNK1E casein kinase 1, epsilon 1.23916
CLK2 CDC-like kinase 2 1.22432
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.20983
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.20983
RIOK2 RIO kinase 2 1.20983
EPHB6 EPH receptor B6 1.19568
CLK4 CDC-like kinase 4 1.19568
NEK9 NIMA-related kinase 9 1.19568
GAK cyclin G associated kinase 1.16838
RIPK2 receptor-interacting serine-threonine kinase 2 1.16838
IRAK1 interleukin-1 receptor-associated kinase 1 1.15523
CSNK1D casein kinase 1, delta 1.15523
STK16 serine/threonine kinase 16 1.15523
ULK2 unc-51 like autophagy activating kinase 2 1.1424
TAOK1 TAO kinase 1 1.12988
DAPK1 death-associated protein kinase 1 1.10576
CLK3 CDC-like kinase 3 1.10576
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.06105
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.05577
DAPK3 death-associated protein kinase 3 1.05057
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.03041
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.03041
LCK LCK proto-oncogene, Src family tyrosine kinase 1.02071
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.02071
CDKL3 cyclin-dependent kinase-like 3 1.01596
CDK7 cyclin-dependent kinase 7 1.01127
AXL AXL receptor tyrosine kinase 0.984392
HIPK4 homeodomain interacting protein kinase 4 0.984392
AURKC aurora kinase C 0.975893
STK33 serine/threonine kinase 33 0.967615
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.967615
NLK nemo-like kinase 0.959553
ULK1 unc-51 like autophagy activating kinase 1 0.959553
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.955601
AAK1 AP2 associated kinase 1 0.947851
BMP2K BMP2 inducible kinase 0.940302
STK36 serine/threonine kinase 36 0.929345
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.922275
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 0.902136
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.895762
BLK BLK proto-oncogene, Src family tyrosine kinase 0.883492
ERBB3 erb-b2 receptor tyrosine kinase 3 0.877587
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.877587
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.874689
MELK maternal embryonic leucine zipper kinase 0.871827
STK17B serine/threonine kinase 17b 0.866209
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.860727
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.855378
ADCK3 aarF domain containing kinase 3 0.850157
ULK3 unc-51 like kinase 3 0.850157