CR2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description complement component (3d/Epstein Barr virus) receptor 2|This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 1380)
External Link https://ncbi.nlm.nih.gov/gene/1380
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Genes

499 genes differentially expressed following the CR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0170317
KRT14 keratin 14, type I 0.0168369
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0129799
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0128441
JCHAIN joining chain of multimeric IgA and IgM 0.0127512
AMIGO2 adhesion molecule with Ig-like domain 2 0.0126355
PLAAT3 phospholipase A and acyltransferase 3 0.0120623
S100A10 S100 calcium binding protein A10 0.0112589
FN1 fibronectin 1 0.0108736
FST follistatin 0.0105547
CRYAB crystallin, alpha B 0.0105456
KRT5 keratin 5, type II 0.0103564
DDIT3 DNA-damage-inducible transcript 3 0.0102911
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0101111
FKBP11 FK506 binding protein 11, 19 kDa 0.00998705
STK26 serine/threonine protein kinase 26 0.00993991
VEGFA vascular endothelial growth factor A 0.00966146
CSTA cystatin A (stefin A) 0.0096561
HTRA1 HtrA serine peptidase 1 0.00962594
AKR1C2 aldo-keto reductase family 1, member C2 0.00962312
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00962077
KRT17 keratin 17, type I 0.00961892
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00935426
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00925816
KDM5D lysine (K)-specific demethylase 5D 0.00922593
CA12 carbonic anhydrase XII 0.00916164
TM4SF1 transmembrane 4 L six family member 1 0.00906877
INAVA innate immunity activator 0.00893818
CXCL13 chemokine (C-X-C motif) ligand 13 0.00890619
ARMCX1 armadillo repeat containing, X-linked 1 0.00880718
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00866287
KRT16 keratin 16, type I 0.00847698
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00843081
MZB1 marginal zone B and B1 cell-specific protein 0.00836835
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00836197
TFPI2 tissue factor pathway inhibitor 2 0.0082301
MT1X metallothionein 1X 0.0082201
NVL nuclear VCP-like 0.0081782
HSPA1A heat shock 70kDa protein 1A 0.00817098
COCH cochlin 0.00808355
BPGM 2,3-bisphosphoglycerate mutase 0.00807679
CDC20 cell division cycle 20 0.00807165
KRT6A keratin 6A, type II 0.00805837
AMOTL2 angiomotin like 2 0.00805153
PLK2 polo-like kinase 2 0.00800757
AKR1C1 aldo-keto reductase family 1, member C1 0.00793868
FXYD2 FXYD domain containing ion transport regulator 2 0.00790594
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0078906
AHNAK2 AHNAK nucleoprotein 2 0.00788389
POU2AF1 POU class 2 associating factor 1 0.00783332
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00780445
TACSTD2 tumor-associated calcium signal transducer 2 0.00779925
SLPI secretory leukocyte peptidase inhibitor 0.00776405
PYCARD PYD and CARD domain containing 0.00772443
STC2 stanniocalcin 2 0.00766881
VAMP8 vesicle-associated membrane protein 8 0.00764402
UPP1 uridine phosphorylase 1 0.00758815
XCL1 chemokine (C motif) ligand 1 0.007438
COG7 component of oligomeric golgi complex 7 0.00738532
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00735442
CD9 CD9 molecule 0.00733566
IPO13 importin 13 0.00731877
CXCL9 chemokine (C-X-C motif) ligand 9 0.0073182
KRT6B keratin 6B, type II 0.00729356
SFN stratifin 0.00719675
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00718695
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00713377
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00713088
ASS1 argininosuccinate synthase 1 0.00712009
INHBA inhibin, beta A 0.00711657
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0070395
PERP PERP, TP53 apoptosis effector 0.0070275
SMAD7 SMAD family member 7 0.00702065
PEG10 paternally expressed 10 0.00702057
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00700611
KRT7 keratin 7, type II 0.00698263
KRT15 keratin 15, type I 0.00695948
DSP desmoplakin 0.00693952
PDZK1IP1 PDZK1 interacting protein 1 0.00690618
LITAF lipopolysaccharide-induced TNF factor 0.00689801
ANXA4 annexin A4 0.00688683
AKAP9 A kinase (PRKA) anchor protein 9 0.00684413
PDGFC platelet derived growth factor C 0.00681971
WASHC4 WASH complex subunit 4 0.00669398
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00669383
MAMLD1 mastermind-like domain containing 1 0.00667904
HMOX1 heme oxygenase 1 0.0066349
DPP4 dipeptidyl-peptidase 4 0.00661508
BAMBI BMP and activin membrane-bound inhibitor 0.00660223
PTK2B protein tyrosine kinase 2 beta 0.00659391
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00657954
PXDC1 PX domain containing 1 0.00653385
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00651474
S100A11 S100 calcium binding protein A11 0.00651223
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00650065
KRT19 keratin 19, type I 0.00647853
APOD apolipoprotein D 0.00645624
CRISP3 cysteine-rich secretory protein 3 0.00644779
LGALS3 lectin, galactoside-binding, soluble, 3 0.00644057
TRIM29 tripartite motif containing 29 0.00643717
DEFB1 defensin, beta 1 0.00641763
NDRG1 N-myc downstream regulated 1 0.00639386
CD37 CD37 molecule 0.00635859
TUFT1 tuftelin 1 0.00632574
ZBED2 zinc finger, BED-type containing 2 0.00631292
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00630206
FRZB frizzled-related protein 0.00625106
ADM adrenomedullin 0.00623974
EPS8L2 EPS8-like 2 0.00623746
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00623457
KRT23 keratin 23, type I 0.00620459
MT1G metallothionein 1G 0.00618435
DUSP5 dual specificity phosphatase 5 0.00611978
SOWAHC sosondowah ankyrin repeat domain family member C 0.00609021
BMP4 bone morphogenetic protein 4 0.00607885
IGFBP6 insulin-like growth factor binding protein 6 0.00607589
RPS27L ribosomal protein S27-like 0.00606746
OSBPL10 oxysterol binding protein-like 10 0.00604116
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.00603904
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.00599135
SIX2 SIX homeobox 2 0.00597405
RALB v-ral simian leukemia viral oncogene homolog B 0.00596446
RBM47 RNA binding motif protein 47 0.00596284
CALB1 calbindin 1, 28kDa 0.00594911
OSBPL1A oxysterol binding protein-like 1A 0.00592867
MT1E metallothionein 1E 0.00591793
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00585744
TARP TCR gamma alternate reading frame protein 0.00584981
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00584056
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00582442
PTHLH parathyroid hormone-like hormone 0.00581224
TXN thioredoxin 0.00580783
GNLY granulysin 0.00579707
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00579444
CCNG2 cyclin G2 0.00578122
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00577334
MT1HL1 metallothionein 1H-like 1 0.00576558
FSCN1 fascin actin-bundling protein 1 0.00576057
CRCT1 cysteine-rich C-terminal 1 0.00572852
MINK1 misshapen-like kinase 1 0.00569091
RRAGC Ras-related GTP binding C 0.00568841
RHCG Rh family, C glycoprotein 0.00566985
NOTCH2NL notch 2 N-terminal like 0.00566133
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00566024
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00564393
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00562554
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00560424
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00560211
ANXA1 annexin A1 0.00559545
CRYBG1 crystallin beta-gamma domain containing 1 0.00559503
PFKP phosphofructokinase, platelet 0.00559424
TUBA4A tubulin, alpha 4a 0.00559227
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00557333
CALML3 calmodulin-like 3 0.00557105
ARHGAP22 Rho GTPase activating protein 22 0.00555059
LAMC2 laminin, gamma 2 0.00553045
CDA cytidine deaminase 0.00552948
KL klotho 0.00552723
MT1F metallothionein 1F 0.00552048
PTPRK protein tyrosine phosphatase, receptor type, K 0.00549591
IRF4 interferon regulatory factor 4 0.00548507
PDLIM1 PDZ and LIM domain 1 0.00545786
DOCK4 dedicator of cytokinesis 4 0.00545469
LDOC1 leucine zipper, down-regulated in cancer 1 0.00545312
CAPG capping protein (actin filament), gelsolin-like 0.0054512
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0054365
BTF3P11 basic transcription factor 3 pseudogene 11 0.00542004
COL9A2 collagen, type IX, alpha 2 0.00539745
LGALS2 lectin, galactoside-binding, soluble, 2 0.00536877
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00535145
FAM117A family with sequence similarity 117, member A 0.00534844
FAM110B family with sequence similarity 110, member B 0.00533934
NEU1 sialidase 1 (lysosomal sialidase) 0.00533598
POSTN periostin, osteoblast specific factor 0.00532756
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00531362
CAVIN3 caveolae associated protein 3 0.00528427
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00527649
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.00525071
GLS glutaminase 0.0052485
SERTAD2 SERTA domain containing 2 0.00523307
CKS2 CDC28 protein kinase regulatory subunit 2 0.00522263
PKP1 plakophilin 1 0.0052143
CAPN2 calpain 2, (m/II) large subunit 0.00521194
MAST4 microtubule associated serine/threonine kinase family member 4 0.00520766
VEGFC vascular endothelial growth factor C 0.00520089
CDH16 cadherin 16, KSP-cadherin 0.00518943
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00518559
DIPK1A divergent protein kinase domain 1A 0.00518388
AKR1C3 aldo-keto reductase family 1, member C3 0.00515333
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00514746
S100A14 S100 calcium binding protein A14 0.00514341
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00514226
COMP cartilage oligomeric matrix protein 0.00514197
HDAC9 histone deacetylase 9 0.00514045
NRG1 neuregulin 1 0.00512675
MT1H metallothionein 1H 0.00512304
PPL periplakin 0.00508943
S100A2 S100 calcium binding protein A2 0.00505628
HOMER3 homer scaffolding protein 3 0.00505539
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00504635
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00504435
SCPEP1 serine carboxypeptidase 1 0.00503999
HMGN3 high mobility group nucleosomal binding domain 3 0.00502942
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.0050262
EFHD1 EF-hand domain family, member D1 0.00500986
FNDC3B fibronectin type III domain containing 3B 0.0050029
HK2 hexokinase 2 0.00499072
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00499
EN1 engrailed homeobox 1 0.00498818
COL11A1 collagen, type XI, alpha 1 0.00498024
CXCL11 chemokine (C-X-C motif) ligand 11 0.00496732
MIR22HG MIR22 host gene 0.00496001
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 0.00495624
USP3 ubiquitin specific peptidase 3 0.00495252
KRTAP1-1 keratin associated protein 1-1 0.00493765
RBM34 RNA binding motif protein 34 0.00493352
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00491881
BTG1 B-cell translocation gene 1, anti-proliferative 0.00491784
YBX3 Y box binding protein 3 0.00491672
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00490618
AKAP8 A kinase (PRKA) anchor protein 8 0.0049042
ACAN aggrecan 0.00486981
TGFA transforming growth factor, alpha 0.00486634
WARS1 tryptophanyl-tRNA synthetase 1 0.00485713
ODC1 ornithine decarboxylase 1 0.00485667
ANXA2P2 annexin A2 pseudogene 2 0.00483898
FOLR1 folate receptor 1 (adult) 0.00482704
GAS6 growth arrest-specific 6 0.00482689
TMPRSS4 transmembrane protease, serine 4 0.00480146
CD19 CD19 molecule 0.00479419
MYOF myoferlin 0.00479096
WNT5B wingless-type MMTV integration site family, member 5B 0.00477425
SSR4 signal sequence receptor, delta 0.00477286
COL4A6 collagen, type IV, alpha 6 0.0047691
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00476704
IQGAP1 IQ motif containing GTPase activating protein 1 0.00475638
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00474757
RBBP6 retinoblastoma binding protein 6 0.00473341
DGKA diacylglycerol kinase, alpha 80kDa 0.00471159
RND3 Rho family GTPase 3 0.00469098
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.00468287
CD79B CD79b molecule, immunoglobulin-associated beta 0.00465454
CTNND1 catenin (cadherin-associated protein), delta 1 0.0046492
MVP major vault protein 0.00464847
LTF lactotransferrin 0.00463935
STAT4 signal transducer and activator of transcription 4 0.00463655
LYPD3 LY6/PLAUR domain containing 3 0.00463201
USP9Y ubiquitin specific peptidase 9, Y-linked 0.0046228
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.00462057
HIST1H2BD histone cluster 1, H2bd 0.00461701

decreased expression

Symbol Name Standardized Value
ARID4A AT rich interactive domain 4A (RBP1-like) -0.011804
HBB hemoglobin, beta -0.011225
XIC X chromosome inactivation center -0.0108495
C8ORF4 chromosome 8 open reading frame 4 -0.0106708
SDC2 syndecan 2 -0.0100833
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.0100205
FZD6 frizzled class receptor 6 -0.00995508
NRN1 neuritin 1 -0.00965769
FABP4 fatty acid binding protein 4, adipocyte -0.00936263
MTUS1 microtubule associated tumor suppressor 1 -0.00906836
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00901984
SPARCL1 SPARC-like 1 (hevin) -0.00901412
OLFM1 olfactomedin 1 -0.00886107
FKBP5 FK506 binding protein 5 -0.00884234
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00880784
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00865413
ALCAM activated leukocyte cell adhesion molecule -0.00864373
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00859334
APOLD1 apolipoprotein L domain containing 1 -0.00825127
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0082462
C7 complement component 7 -0.00814176
CFI complement factor I -0.00804641
SCAMP1 secretory carrier membrane protein 1 -0.00802197
LAMA4 laminin, alpha 4 -0.00778755
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00773325
FGFR3 fibroblast growth factor receptor 3 -0.00770758
EGR3 early growth response 3 -0.00768022
GLUL glutamate-ammonia ligase -0.00767154
PLAT plasminogen activator, tissue -0.00763873
CD93 CD93 molecule -0.0075401
RAD23B RAD23 homolog B (S. cerevisiae) -0.00753658
SEPP1 selenoprotein P, plasma, 1 -0.00752976
TMEM204 transmembrane protein 204 -0.00747505
AKAP12 A kinase (PRKA) anchor protein 12 -0.0074094
LAPTM5 lysosomal protein transmembrane 5 -0.00740265
NLGN4X neuroligin 4, X-linked -0.00723996
ADD3 adducin 3 (gamma) -0.00723929
MECOM MDS1 and EVI1 complex locus -0.00721224
HSPB1 heat shock 27kDa protein 1 -0.00720174
SCD5 stearoyl-CoA desaturase 5 -0.00707003
LMNB1 lamin B1 -0.00696354
RRAGA Ras-related GTP binding A -0.00688649
SLIT2 slit homolog 2 (Drosophila) -0.00688045
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00686076
GPC3 glypican 3 -0.00683828
VWF von Willebrand factor -0.00680197
SRPX sushi-repeat containing protein, X-linked -0.00676011
COPS7A COP9 signalosome subunit 7A -0.0067395
PRMT1 protein arginine methyltransferase 1 -0.00671691
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00670832
DPYSL3 dihydropyrimidinase-like 3 -0.00669383
DDHD2 DDHD domain containing 2 -0.00667
SMC1A structural maintenance of chromosomes 1A -0.0065985
OPHN1 oligophrenin 1 -0.00657878
FBN1 fibrillin 1 -0.00646728
SELL selectin L -0.00640393
TSPAN13 tetraspanin 13 -0.00638902
CYBRD1 cytochrome b reductase 1 -0.00638363
ANOS1 anosmin 1 -0.00635707
LEF1 lymphoid enhancer-binding factor 1 -0.00631229
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00626171
GPM6A glycoprotein M6A -0.00624998
PBK PDZ binding kinase -0.00623765
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00622863
B3GNT1 -0.00619888
SRSF1 serine/arginine-rich splicing factor 1 -0.00619724
CD36 CD36 molecule (thrombospondin receptor) -0.00617997
CAVIN2 caveolae associated protein 2 -0.00617651
SPON1 spondin 1, extracellular matrix protein -0.0061382
HP haptoglobin -0.00608976
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0060824
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00607585
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00606849
PDGFRL platelet-derived growth factor receptor-like -0.00606283
EIF5A eukaryotic translation initiation factor 5A -0.00605693
CST3 cystatin C -0.00604365
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00604227
CTSK cathepsin K -0.00602989
PEA15 phosphoprotein enriched in astrocytes 15 -0.00597977
CDH5 cadherin 5, type 2 (vascular endothelium) -0.005976
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00596374
EPHB2 EPH receptor B2 -0.00596203
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00595014
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00592265
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00590694
TWIST1 twist family bHLH transcription factor 1 -0.00589191
GPR183 G protein-coupled receptor 183 -0.00589127
MSL1 male-specific lethal 1 homolog (Drosophila) -0.00586355
INSR insulin receptor -0.00585624
F13A1 coagulation factor XIII, A1 polypeptide -0.00582116
IFI16 interferon, gamma-inducible protein 16 -0.00581428
NID1 nidogen 1 -0.00579078
AKAP7 A kinase (PRKA) anchor protein 7 -0.00578394
COL18A1 collagen, type XVIII, alpha 1 -0.0057647
PRKD3 protein kinase D3 -0.0057623
GARS1 glycyl-tRNA synthetase 1 -0.00575787
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00574085
TYRP1 tyrosinase-related protein 1 -0.00572951
ITGA6 integrin, alpha 6 -0.00571453
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00570869
PBX1 pre-B-cell leukemia homeobox 1 -0.00569837
FXYD6 FXYD domain containing ion transport regulator 6 -0.00569022
KIF20A kinesin family member 20A -0.00569012
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.0056857
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00565714
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00565617
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00564975
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00563594
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00562917
CLEC2B C-type lectin domain family 2, member B -0.00562827
FOXF1 forkhead box F1 -0.0056279
PDZD2 PDZ domain containing 2 -0.0056029
DMD dystrophin -0.00559896
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00559113
CD163 CD163 molecule -0.00556609
FPGS folylpolyglutamate synthase -0.00555753
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00554382
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00554381
ADCY3 adenylate cyclase 3 -0.00553313
LIG1 ligase I, DNA, ATP-dependent -0.00551658
TFF3 trefoil factor 3 (intestinal) -0.00550409
PLPBP pyridoxal phosphate binding protein -0.005503
DIO2 deiodinase, iodothyronine, type II -0.00549222
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00548317
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00546924
RELN reelin -0.00546783
EDNRB endothelin receptor type B -0.00546096
ELOVL2 ELOVL fatty acid elongase 2 -0.00545699
MMD monocyte to macrophage differentiation-associated -0.00545433
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00544464
CPVL carboxypeptidase, vitellogenic-like -0.00544382
FABP1 fatty acid binding protein 1, liver -0.00542798
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00542411
AZIN1 antizyme inhibitor 1 -0.00541614
HYOU1 hypoxia up-regulated 1 -0.00541329
PRRX1 paired related homeobox 1 -0.00541002
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00540644
NMU neuromedin U -0.00539639
BIRC5 baculoviral IAP repeat containing 5 -0.00539352
CHN1 chimerin 1 -0.00537185
CLDN5 claudin 5 -0.00536736
LAPTM4B lysosomal protein transmembrane 4 beta -0.0053666
SUB1 SUB1 homolog (S. cerevisiae) -0.00535447
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00534495
MARCKSL1 MARCKS-like 1 -0.00533935
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00533912
BTBD3 BTB (POZ) domain containing 3 -0.00530712
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00529547
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00527842
CD320 CD320 molecule -0.00527337
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00526779
MEF2C myocyte enhancer factor 2C -0.00524892
MOXD1 monooxygenase, DBH-like 1 -0.00519663
F2R coagulation factor II (thrombin) receptor -0.0051917
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00518563
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00512524
TUBB2A tubulin, beta 2A class IIa -0.00512168
AQP4 aquaporin 4 -0.00511419
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00510671
CADPS2 Ca++-dependent secretion activator 2 -0.00510579
TERF2 telomeric repeat binding factor 2 -0.00509226
TCF4 transcription factor 4 -0.00509049
HPF1 histone PARylation factor 1 -0.00507937
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00507314
LOX lysyl oxidase -0.00507204
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00505673
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00505561
THBS4 thrombospondin 4 -0.00505248
GANAB glucosidase, alpha; neutral AB -0.00505213
SOX17 SRY (sex determining region Y)-box 17 -0.00503548
BCL2 B-cell CLL/lymphoma 2 -0.00502468
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00501977
STK10 serine/threonine kinase 10 -0.00501353
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00501294
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00500126
GAA glucosidase, alpha; acid -0.00499498
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.0049924
MDK midkine (neurite growth-promoting factor 2) -0.00498371
FKBP10 FK506 binding protein 10, 65 kDa -0.00498317
CDC42 cell division cycle 42 -0.00497119
EMP2 epithelial membrane protein 2 -0.00497025
EDN3 endothelin 3 -0.00496463
GLTP glycolipid transfer protein -0.0049644
KIF1B kinesin family member 1B -0.00495656
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.0049528
LRRC17 leucine rich repeat containing 17 -0.00494844
STMN2 stathmin 2 -0.00494449
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00491976
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.0049179
SORD sorbitol dehydrogenase -0.00491534
EPAS1 endothelial PAS domain protein 1 -0.00490313
MSX1 msh homeobox 1 -0.00490266
CIRBP cold inducible RNA binding protein -0.00490177
MAB21L2 mab-21-like 2 (C. elegans) -0.00489133
WFDC2 WAP four-disulfide core domain 2 -0.00488825
FCGBP Fc fragment of IgG binding protein -0.0048354
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00483442
IL1R1 interleukin 1 receptor, type I -0.00482881
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00482577
ASF1B anti-silencing function 1B histone chaperone -0.00482573
PCYOX1L prenylcysteine oxidase 1 like -0.0048204
SPC25 SPC25, NDC80 kinetochore complex component -0.00481659
RAPSN receptor-associated protein of the synapse -0.00480216
SCARB2 scavenger receptor class B, member 2 -0.00479769
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00479593
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00478975
SAMM50 SAMM50 sorting and assembly machinery component -0.00478732
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00478622
CCNF cyclin F -0.00478516
ALPL alkaline phosphatase, liver/bone/kidney -0.00478225
SYK spleen tyrosine kinase -0.00477348
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00477252
LDB2 LIM domain binding 2 -0.00476589
ANO1 anoctamin 1, calcium activated chloride channel -0.00475809
PLP1 proteolipid protein 1 -0.00475673
RER1 retention in endoplasmic reticulum sorting receptor 1 -0.00475288
SPP1 secreted phosphoprotein 1 -0.00475177
DHCR24 24-dehydrocholesterol reductase -0.00474156
TMOD1 tropomodulin 1 -0.00472324
CALCRL calcitonin receptor-like -0.00472089
LMAN1 lectin, mannose-binding, 1 -0.00471606
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00470828
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0047071
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.0047019
CTBP1 C-terminal binding protein 1 -0.00469752
KIF15 kinesin family member 15 -0.00469436
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00468679
ERLIN2 ER lipid raft associated 2 -0.00468488
LRP4 low density lipoprotein receptor-related protein 4 -0.00467433
VCP valosin containing protein -0.00466573
KLF9 Kruppel-like factor 9 -0.0046616
EXOC5 exocyst complex component 5 -0.00465561
NFIB nuclear factor I/B -0.00464775
SYBU syntabulin (syntaxin-interacting) -0.00463503
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00463461
NEK2 NIMA-related kinase 2 -0.00463384
OIP5 Opa interacting protein 5 -0.00462718
CD302 CD302 molecule -0.00462244
TSPAN5 tetraspanin 5 -0.00461887
C1R complement component 1, r subcomponent -0.00459911
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.00459654
PTCH1 patched 1 -0.00459058
DLAT dihydrolipoamide S-acetyltransferase -0.00458893
DCAF10 DDB1 and CUL4 associated factor 10 -0.00458549
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0045837
LYZ lysozyme -0.00458316
CCNB1 cyclin B1 -0.00458166
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.00457504
BEX1 brain expressed, X-linked 1 -0.00456375