| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN008_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.0648 |
| HOXA10 | homeobox A10 | 5.40235 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.048 |
| SQOR | sulfide quinone oxidoreductase | 4.82595 |
| E2F2 | E2F transcription factor 2 | 4.8026 |
| UBQLN2 | ubiquilin 2 | 4.7641 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 4.04513 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.03947 |
| ARL4C | ADP-ribosylation factor-like 4C | 3.92133 |
| EGF | epidermal growth factor | 3.73 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.72355 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.53192 |
| MAP7 | microtubule-associated protein 7 | 3.19083 |
| SFTPB | surfactant protein B | 2.98542 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.83168 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.75902 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.72705 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 2.5611 |
| CD177 | CD177 molecule | 2.4636 |
| TSPYL1 | TSPY-like 1 | 2.41325 |
| APP | amyloid beta (A4) precursor protein | 2.36468 |
| TLR4 | toll-like receptor 4 | 2.3568 |
| TSPYL4 | TSPY-like 4 | 2.3495 |
| EIF4H | eukaryotic translation initiation factor 4H | 2.27515 |
| MACROD1 | MACRO domain containing 1 | 2.27435 |
| SFTPD | surfactant protein D | 2.2514 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G | 2.1709 |
| GATA2 | GATA binding protein 2 | 2.13663 |
| RPL34 | ribosomal protein L34 | 2.12155 |
| KLHL12 | kelch-like family member 12 | 2.10965 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.0873 |
| BEST2 | bestrophin 2 | 2.07735 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 2.06335 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.03708 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z | 2.02005 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.01775 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 2.0098 |
| COX6C | cytochrome c oxidase subunit VIc | 2.0011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -7.37735 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.014 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.85895 |
| PCNA | proliferating cell nuclear antigen | -4.81965 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.11508 |
| SCAND1 | SCAN domain containing 1 | -3.80345 |
| CCNB1 | cyclin B1 | -3.66215 |
| HMG20B | high mobility group 20B | -3.087 |
| PDZD2 | PDZ domain containing 2 | -2.99447 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.81975 |
| RNF167 | ring finger protein 167 | -2.723 |
| ADAP2 | ArfGAP with dual PH domains 2 | -2.6444 |
| SNX11 | sorting nexin 11 | -2.61125 |
| WASHC4 | WASH complex subunit 4 | -2.58013 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -2.55255 |
| MMD | monocyte to macrophage differentiation-associated | -2.54465 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.4435 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.43887 |
| ZW10 | zw10 kinetochore protein | -2.36685 |
| RAI14 | retinoic acid induced 14 | -2.33415 |
| AADAC | arylacetamide deacetylase | -2.32625 |
| NTS | neurotensin | -2.2323 |
| INHBB | inhibin, beta B | -2.2215 |
| CSRP2 | cysteine and glycine-rich protein 2 | -2.21133 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.1981 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -2.19785 |
| MTA1 | metastasis associated 1 | -2.12462 |
| LGMN | legumain | -2.1245 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.1236 |
| GBA1 | glucosylceramidase beta 1 | -2.11425 |
| ADRA2A | adrenoceptor alpha 2A | -2.07765 |
| DNAL4 | dynein, axonemal, light chain 4 | -2.0316 |
| MNT | MAX network transcriptional repressor | -2.02725 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 | -2.0268 |
| IL18RAP | interleukin 18 receptor accessory protein | -2.00605 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -2.0024 |
