CRCGN008_HEPG2_24H:A04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1046 genes differentially expressed following the CRCGN008_HEPG2_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 10.0
PPARG peroxisome proliferator-activated receptor gamma 10.0
NR1H2 nuclear receptor subfamily 1, group H, member 2 10.0
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 10.0
MYLK myosin light chain kinase 10.0
ADRB2 adrenoceptor beta 2, surface 5.98865
STIMATE STIM activating enhancer 5.9272
INTS3 integrator complex subunit 3 5.54775
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.34185
E2F2 E2F transcription factor 2 5.33725
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.22445
ATP11B ATPase, class VI, type 11B 5.1528
CXCL2 chemokine (C-X-C motif) ligand 2 5.10105
EPHB2 EPH receptor B2 5.09487
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.03565
ANO1 anoctamin 1, calcium activated chloride channel 5.0
TAC4 tachykinin 4 (hemokinin) 5.0
CHMP6 charged multivesicular body protein 6 4.9615
VAV3 vav 3 guanine nucleotide exchange factor 4.9164
IL1B interleukin 1, beta 4.87667
CBR3 carbonyl reductase 3 4.8609
MCOLN1 mucolipin 1 4.8079
PNKP polynucleotide kinase 3'-phosphatase 4.76875
DYNLT3 dynein, light chain, Tctex-type 3 4.7584
AMDHD2 amidohydrolase domain containing 2 4.75315
GSTZ1 glutathione S-transferase zeta 1 4.6941
STAP2 signal transducing adaptor family member 2 4.6486
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.6237
ADGRE5 adhesion G protein-coupled receptor E5 4.59265
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.59016
MSRA methionine sulfoxide reductase A 4.49045
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.27495
NOTCH1 notch 1 4.26655
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.251
TIMP2 TIMP metallopeptidase inhibitor 2 4.2487
ETV1 ets variant 1 4.23925
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 4.228
PEX11A peroxisomal biogenesis factor 11 alpha 4.22227
BACE2 beta-site APP-cleaving enzyme 2 4.1924
MICALL1 MICAL-like 1 4.14435
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.14418
GPER1 G protein-coupled estrogen receptor 1 4.12165
CD40 CD40 molecule, TNF receptor superfamily member 5 4.09161
STK10 serine/threonine kinase 10 4.08695
PRKCH protein kinase C, eta 4.0568
CXCR4 chemokine (C-X-C motif) receptor 4 3.95702
LOC122526780 uncharacterized LOC122526780 3.9403
L1TD1 LINE-1 type transposase domain containing 1 3.9387
UTF1 undifferentiated embryonic cell transcription factor 1 3.91735
PFKL phosphofructokinase, liver 3.91662
ADIRF adipogenesis regulatory factor 3.91215
SSBP2 single-stranded DNA binding protein 2 3.89698
MTERF3 mitochondrial transcription termination factor 3 3.7863
GPS1 G protein pathway suppressor 1 3.7562
RRAGA Ras-related GTP binding A 3.7259
CARMIL1 capping protein regulator and myosin 1 linker 1 3.683
KIAA0513 KIAA0513 3.64715
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 3.62632
KLHL21 kelch-like family member 21 3.60775
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 3.60517
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 3.5498
PIH1D1 PIH1 domain containing 1 3.5447
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 3.54125
KLRC1 killer cell lectin-like receptor subfamily C, member 1 3.53045
KDM5A lysine (K)-specific demethylase 5A 3.52083
NAP1L2 nucleosome assembly protein 1-like 2 3.50285
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 3.49345
GATA3 GATA binding protein 3 3.47977
PRR15L proline rich 15-like 3.459
GARRE1 granule associated Rac and RHOG effector 1 3.4304
AP2M1 adaptor-related protein complex 2, mu 1 subunit 3.42435
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 3.4041
ARL4C ADP-ribosylation factor-like 4C 3.3923
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 3.3541
RXYLT1 ribitol xylosyltransferase 1 3.35225
TPGS1 tubulin polyglutamylase complex subunit 1 3.338
TIAM1 T-cell lymphoma invasion and metastasis 1 3.32057
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.28475
MARCHF8 membrane associated ring-CH-type finger 8 3.27865
ZNF365 zinc finger protein 365 3.27795
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.27617
MTM1 myotubularin 1 3.26478
SCRN1 secernin 1 3.22475
MIA melanoma inhibitory activity 3.21825
CCL4 chemokine (C-C motif) ligand 4 3.21325
KPTN kaptin (actin binding protein) 3.1683
FN3K fructosamine 3 kinase 3.16465
WNT5B wingless-type MMTV integration site family, member 5B 3.1622
PLS1 plastin 1 3.16125
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 3.15785
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 3.15363
JADE2 jade family PHD finger 2 3.14937
TTLL4 tubulin tyrosine ligase-like family member 4 3.12793
NAPSA napsin A aspartic peptidase 3.1245
TESK2 testis-specific kinase 2 3.11235
NANOS3 nanos homolog 3 (Drosophila) 3.10655
SATB1 SATB homeobox 1 3.10585
HOXA7 homeobox A7 3.0962
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.0944
ARHGAP19 Rho GTPase activating protein 19 3.07908
KIF5C kinesin family member 5C 3.05648
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 3.04935
SEC14L4 SEC14-like 4 (S. cerevisiae) 3.0378
PDLIM4 PDZ and LIM domain 4 3.02668
DCAF11 DDB1 and CUL4 associated factor 11 3.01823
CAPN5 calpain 5 3.01505
GATA2 GATA binding protein 2 3.00937
GPR161 G protein-coupled receptor 161 3.009
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.99875
SSTR1 somatostatin receptor 1 2.98885
EFNA4 ephrin-A4 2.9879
NKX2-8 NK2 homeobox 8 2.98505
GCM1 glial cells missing homolog 1 (Drosophila) 2.9848
PRSS3 protease, serine, 3 2.98382
CROT carnitine O-octanoyltransferase 2.98145
NR5A2 nuclear receptor subfamily 5, group A, member 2 2.97625
CCRL2 chemokine (C-C motif) receptor-like 2 2.9755
TNRC6B trinucleotide repeat containing 6B 2.9661
MTG1 mitochondrial ribosome-associated GTPase 1 2.9573
CCL8 chemokine (C-C motif) ligand 8 2.9517
MAGEC3 melanoma antigen family C3 2.9503
CRTAM cytotoxic and regulatory T cell molecule 2.9424
PLD3 phospholipase D family, member 3 2.938
MCTP1 multiple C2 domains, transmembrane 1 2.93345
CAPN11 calpain 11 2.91655
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 2.9005
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.8914
PLSCR1 phospholipid scramblase 1 2.89103
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.8823
SPATA17 spermatogenesis associated 17 2.8799
GPATCH3 G patch domain containing 3 2.87265
CCNF cyclin F 2.86812
DHRS11 dehydrogenase/reductase (SDR family) member 11 2.86325
POU3F3 POU class 3 homeobox 3 2.8607
NAGK N-acetylglucosamine kinase 2.85775
SMG9 SMG9 nonsense mediated mRNA decay factor 2.84785
MYLIP myosin regulatory light chain interacting protein 2.8452
COQ8B coenzyme Q8B 2.84395
GDAP2 ganglioside induced differentiation associated protein 2 2.8417
SHH sonic hedgehog 2.8402
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 2.83
TNIP3 TNFAIP3 interacting protein 3 2.8281
EVA1B eva-1 homolog B (C. elegans) 2.82295
SASH1 SAM and SH3 domain containing 1 2.81998
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2.81871
IFNG interferon, gamma 2.8185
CCL1 chemokine (C-C motif) ligand 1 2.81525
BAX BCL2-associated X protein 2.81493
MRPL30 mitochondrial ribosomal protein L30 2.80755
FPGS folylpolyglutamate synthase 2.8068
SLC49A3 solute carrier family 49 member 3 2.8046
LPXN leupaxin 2.80305
CHN1 chimerin 1 2.8001
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.79705
RXFP3 relaxin/insulin-like family peptide receptor 3 2.7871
BBX bobby sox homolog (Drosophila) 2.7859
PNPLA6 patatin-like phospholipase domain containing 6 2.78585
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.7842
MCTP2 multiple C2 domains, transmembrane 2 2.7803
ZNF331 zinc finger protein 331 2.778
IL12A interleukin 12A 2.7738
FOXD2 forkhead box D2 2.7736
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.7735
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 2.77175
DUSP3 dual specificity phosphatase 3 2.76723
ITPKB inositol-trisphosphate 3-kinase B 2.76675
EPB42 erythrocyte membrane protein band 4.2 2.7667
IDUA iduronidase, alpha-L- 2.76642
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.7663
MAN2C1 mannosidase, alpha, class 2C, member 1 2.765
ATP13A2 ATPase type 13A2 2.76115
OPRPN opiorphin prepropeptide 2.76085
MOCS2 molybdenum cofactor synthesis 2 2.7589
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.7568
ULBP2 UL16 binding protein 2 2.7567
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.75625
ZMYM1 zinc finger, MYM-type 1 2.7525
MCPH1 microcephalin 1 2.7512
CEP97 centrosomal protein 97kDa 2.74715
BBS7 Bardet-Biedl syndrome 7 2.74075
CEP83 centrosomal protein 83kDa 2.73655
TUBGCP5 tubulin, gamma complex associated protein 5 2.73405
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.73175
KNG1 kininogen 1 2.72587
FOS FBJ murine osteosarcoma viral oncogene homolog 2.7228
FBXO2 F-box protein 2 2.72155
ELMO3 engulfment and cell motility 3 2.7136
DAAM2 dishevelled associated activator of morphogenesis 2 2.7011
PRSS2 protease, serine, 2 (trypsin 2) 2.69807
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.6977
PYY peptide YY 2.6975
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.6975
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.69715
FOXD3 forkhead box D3 2.6967
EHBP1L1 EH domain binding protein 1-like 1 2.69147
INPP5F inositol polyphosphate-5-phosphatase F 2.68865
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.68725
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.6843
SAYSD1 SAYSVFN motif domain containing 1 2.6823
CXCR6 chemokine (C-X-C motif) receptor 6 2.68132
PKLR pyruvate kinase, liver and RBC 2.67823
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.67365
AIRE autoimmune regulator 2.67355
WWP1 WW domain containing E3 ubiquitin protein ligase 1 2.6647
ARAF A-Raf proto-oncogene, serine/threonine kinase 2.66115
LIPG lipase, endothelial 2.6577
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.6541
ZNF385D zinc finger protein 385D 2.654
RNF38 ring finger protein 38 2.6539
EVL Enah/Vasp-like 2.65325
MKS1 Meckel syndrome, type 1 2.64935
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.64718
GALR2 galanin receptor 2 2.6463
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 2.6401
GSC2 goosecoid homeobox 2 2.6261
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.62595
TBX3 T-box 3 2.625
MAPK4 mitogen-activated protein kinase 4 2.6218
RASL12 RAS-like, family 12 2.6211
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.61875
MAGEA11 melanoma antigen family A11 2.6159
ZNF589 zinc finger protein 589 2.61325
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.6113
BIN3 bridging integrator 3 2.61015
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.60705
PEF1 penta-EF-hand domain containing 1 2.6029
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.60205
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.6017
TLR4 toll-like receptor 4 2.60135
TTPA tocopherol (alpha) transfer protein 2.601
TCF12 transcription factor 12 2.59995
HAUS6 HAUS augmin-like complex, subunit 6 2.59815
WDHD1 WD repeat and HMG-box DNA binding protein 1 2.59305
SYNPO2L synaptopodin 2-like 2.59295
MICA MHC class I polypeptide-related sequence A 2.59078
HELLS helicase, lymphoid-specific 2.5808
IKZF4 IKAROS family zinc finger 4 (Eos) 2.58055
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.5765
FKRP fukutin related protein 2.57115
KRT5 keratin 5, type II 2.5693
S1PR2 sphingosine-1-phosphate receptor 2 2.56835
FIRRM FIGNL1 interacting regulator of recombination and mitosis 2.56485
PDZRN4 PDZ domain containing ring finger 4 2.55815
TRAF1 TNF receptor-associated factor 1 2.55745
CLDN14 claudin 14 2.5568
IRGC immunity-related GTPase family, cinema 2.5563
FAM110A family with sequence similarity 110, member A 2.5551
TBX4 T-box 4 2.5506
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.5497
EXTL1 exostosin-like glycosyltransferase 1 2.5464
IL1A interleukin 1, alpha 2.54555
NLRP1 NLR family, pyrin domain containing 1 2.54452
UBA7 ubiquitin-like modifier activating enzyme 7 2.54405
EPHA3 EPH receptor A3 2.54128
NRG2 neuregulin 2 2.53813
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.53475
MAGEC1 melanoma antigen family C1 2.53435
PRDM8 PR domain containing 8 2.5313
SYNE1 spectrin repeat containing, nuclear envelope 1 2.52887
RIN3 Ras and Rab interactor 3 2.5268
CELA2B chymotrypsin-like elastase family, member 2B 2.5252
PRR5 proline rich 5 (renal) 2.52507
MORC3 MORC family CW-type zinc finger 3 2.52285
GMDS GDP-mannose 4,6-dehydratase 2.52087
PLCD1 phospholipase C, delta 1 2.5198
CBARP CACN subunit beta associated regulatory protein 2.5179
RRAGB Ras-related GTP binding B 2.517
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 2.5132
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.5093
FRK fyn-related Src family tyrosine kinase 2.5062
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.50265
ZNF185 zinc finger protein 185 (LIM domain) 2.50115
SSH1 slingshot protein phosphatase 1 2.5007
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.5004
TCERG1 transcription elongation regulator 1 2.49795
PNLIPRP2 pancreatic lipase-related protein 2 2.49195
FAAP100 FA core complex associated protein 100 2.4913
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.4889
KHDC1L KH homology domain containing 1-like 2.4886
GBP1 guanylate binding protein 1, interferon-inducible 2.48455
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.4844
MYO9B myosin IXB 2.48375
ILF2 interleukin enhancer binding factor 2 2.4827
FAM222B family with sequence similarity 222, member B 2.47835
PORCN porcupine homolog (Drosophila) 2.474
ZNF148 zinc finger protein 148 2.47325
MX1 MX dynamin-like GTPase 1 2.4731
OMP olfactory marker protein 2.4718
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.4695
LTBP4 latent transforming growth factor beta binding protein 4 2.46892
KLHL41 kelch-like family member 41 2.46815
VRK3 vaccinia related kinase 3 2.46605
GUCY2C guanylate cyclase 2C 2.46405
SLIT2 slit homolog 2 (Drosophila) 2.464
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.46235
PILRB paired immunoglobin-like type 2 receptor beta 2.4603
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.4594
ACP6 acid phosphatase 6, lysophosphatidic 2.45925
PCGF3 polycomb group ring finger 3 2.45725
TTC31 tetratricopeptide repeat domain 31 2.4529
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.45245
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.4504
POU1F1 POU class 1 homeobox 1 2.44745
ETV2 ets variant 2 2.43795
NOD2 nucleotide-binding oligomerization domain containing 2 2.43595
PARP16 poly (ADP-ribose) polymerase family, member 16 2.434
NAP1L4 nucleosome assembly protein 1-like 4 2.4324
ACOXL acyl-CoA oxidase-like 2.4302
SLC30A10 solute carrier family 30, member 10 2.4292
FOXB1 forkhead box B1 2.42825
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.4256
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 2.42379
FLT3 fms-related tyrosine kinase 3 2.4228
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.4208
VSNL1 visinin-like 1 2.42077
PLA2G1B phospholipase A2, group IB (pancreas) 2.4189
GMEB1 glucocorticoid modulatory element binding protein 1 2.4114
CDADC1 cytidine and dCMP deaminase domain containing 1 2.41085
QPCTL glutaminyl-peptide cyclotransferase-like 2.4103
AFF3 AF4/FMR2 family, member 3 2.40945
NAGLU N-acetylglucosaminidase, alpha 2.40718
ZNF587 zinc finger protein 587 2.40525
STMN3 stathmin-like 3 2.40495
ZBTB25 zinc finger and BTB domain containing 25 2.4045
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.40435
MTNAP1 mitochondrial nucleoid associated protein 1 2.4035
NEUROG3 neurogenin 3 2.403
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.4028
LRRC19 leucine rich repeat containing 19 2.40185
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.4012
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 2.39992
PDCD1LG2 programmed cell death 1 ligand 2 2.3953
FSCN2 fascin actin-bundling protein 2, retinal 2.39115
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 2.38925
WDR46 WD repeat domain 46 2.38665
VSTM4 V-set and transmembrane domain containing 4 2.3865
LUC7L3 LUC7-like 3 (S. cerevisiae) 2.38525
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.38415
KDM4D lysine (K)-specific demethylase 4D 2.3813
RNF146 ring finger protein 146 2.37945
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.3763
RHOT2 ras homolog family member T2 2.3758
IRF3 interferon regulatory factor 3 2.37555
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.37215
MARCHF2 membrane associated ring-CH-type finger 2 2.3705
COL16A1 collagen, type XVI, alpha 1 2.3705
CPA1 carboxypeptidase A1 (pancreatic) 2.36875
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.36875
ITK IL2-inducible T-cell kinase 2.36795
EREG epiregulin 2.36725
TTYH1 tweety family member 1 2.3672
ULK1 unc-51 like autophagy activating kinase 1 2.3668
NPHP1 nephronophthisis 1 (juvenile) 2.3628
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.36215
PIAS4 protein inhibitor of activated STAT, 4 2.36167
F13B coagulation factor XIII, B polypeptide 2.36105
NUBPL nucleotide binding protein-like 2.35975
ASCL2 achaete-scute family bHLH transcription factor 2 2.3588
ADAT1 adenosine deaminase, tRNA-specific 1 2.3578
HOXA2 homeobox A2 2.3558
DIXDC1 DIX domain containing 1 2.35555
IRF5 interferon regulatory factor 5 2.35515
NOVA1 neuro-oncological ventral antigen 1 2.3543
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.3539
TEX11 testis expressed 11 2.35235
CAMTA2 calmodulin binding transcription activator 2 2.35125
GALK1 galactokinase 1 2.34995
PCDHGC3 protocadherin gamma subfamily C, 3 2.3461
ETNK2 ethanolamine kinase 2 2.34505
SYMPK symplekin 2.34442
PLTP phospholipid transfer protein 2.3424
RGSL1 regulator of G-protein signaling like 1 2.3418
MRPS18C mitochondrial ribosomal protein S18C 2.34045
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.3389
GLRA3 glycine receptor, alpha 3 2.33667
ZXDC ZXD family zinc finger C 2.33525
WRAP73 WD repeat containing, antisense to TP73 2.33445
PBX3 pre-B-cell leukemia homeobox 3 2.33245
SELE selectin E 2.3318
TLR6 toll-like receptor 6 2.3313
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.33125
SPTBN5 spectrin, beta, non-erythrocytic 5 2.32805
JMJD7 jumonji domain containing 7 2.32335
HNRNPM heterogeneous nuclear ribonucleoprotein M 2.3232
BUB1B-PAK6 BUB1B-PAK6 readthrough 2.32223
PRSS16 protease, serine, 16 (thymus) 2.3189
IL10 interleukin 10 2.31455
PCNX1 pecanex 1 2.31433
APOL3 apolipoprotein L, 3 2.31275
FOXF1 forkhead box F1 2.31125
TEX12 testis expressed 12 2.3107
TBXAS1 thromboxane A synthase 1 (platelet) 2.31045
EBF2 early B-cell factor 2 2.30915
APOM apolipoprotein M 2.30855
IGFBP6 insulin-like growth factor binding protein 6 2.30845
CNGA1 cyclic nucleotide gated channel alpha 1 2.30765
ZBTB17 zinc finger and BTB domain containing 17 2.3062
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.3061
MYO5C myosin VC 2.30555
HLF hepatic leukemia factor 2.30522
TLR1 toll-like receptor 1 2.3046
WDR91 WD repeat domain 91 2.30355
CMTR1 cap methyltransferase 1 2.3004
OLFM4 olfactomedin 4 2.3003
TTLL3 tubulin tyrosine ligase-like family member 3 2.29943
LOC124900388 uncharacterized LOC124900388 2.2988
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.2983
FASLG Fas ligand (TNF superfamily, member 6) 2.29798
EPHB6 EPH receptor B6 2.29675
CD5L CD5 molecule-like 2.2967
CELA2A chymotrypsin-like elastase family, member 2A 2.2961
PTN pleiotrophin 2.29535
RPA4 replication protein A4, 30kDa 2.2952
EFHD2 EF-hand domain family, member D2 2.2948
CLEC2D C-type lectin domain family 2, member D 2.2943
TRPC3 transient receptor potential cation channel, subfamily C, member 3 2.29227
BAHCC1 BAH domain and coiled-coil containing 1 2.29165
ZNF276 zinc finger protein 276 2.2896
ADCY8 adenylate cyclase 8 (brain) 2.28935
CXCL3 chemokine (C-X-C motif) ligand 3 2.2853
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.2851
GOLGA4 golgin A4 2.28405
LCOR ligand dependent nuclear receptor corepressor 2.28355
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.2834
GOSR2 golgi SNAP receptor complex member 2 2.28288
MAGIX MAGI family member, X-linked 2.2811
PTHLH parathyroid hormone-like hormone 2.27912
CD96 CD96 molecule 2.2783
FAM110D family with sequence similarity 110, member D 2.27585
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.27445
PCDHA10 protocadherin alpha 10 2.2739
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.27295
SZT2 seizure threshold 2 homolog (mouse) 2.2727
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.27255
RSBN1 round spermatid basic protein 1 2.27185
TRIM2 tripartite motif containing 2 2.27133
ACO1 aconitase 1, soluble 2.27105
EMC10 ER membrane protein complex subunit 10 2.27055
WRN Werner syndrome, RecQ helicase-like 2.2704
MSTN myostatin 2.2696
ADH6 alcohol dehydrogenase 6 (class V) 2.26557
CDK9 cyclin-dependent kinase 9 2.26485
TLX1 T-cell leukemia homeobox 1 2.26295
NANOG Nanog homeobox 2.26265
TGM4 transglutaminase 4 2.25892
ZBTB20 zinc finger and BTB domain containing 20 2.25852
STXBP2 syntaxin binding protein 2 2.25775
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.25765
SIRT6 sirtuin 6 2.25735
ACP3 acid phosphatase 3 2.2573
OSBPL7 oxysterol binding protein-like 7 2.25655
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.2559
SMR3B submaxillary gland androgen regulated protein 3B 2.25555
RAB4A RAB4A, member RAS oncogene family 2.25512
SPHK1 sphingosine kinase 1 2.25505
PLAGL1 pleiomorphic adenoma gene-like 1 2.25363
ADGRE2 adhesion G protein-coupled receptor E2 2.25315
GRIK4 glutamate receptor, ionotropic, kainate 4 2.2524
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 2.2517
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.2504
ZBTB33 zinc finger and BTB domain containing 33 2.2499
EPHX2 epoxide hydrolase 2, cytoplasmic 2.24835
NANOS2 nanos homolog 2 (Drosophila) 2.2471
PRND prion protein 2 (dublet) 2.24655
CNMD chondromodulin 2.245
MNMIP1 manchette microtubule inner protein 1 2.2428
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.24045
FER fer (fps/fes related) tyrosine kinase 2.23985
SYNJ2BP synaptojanin 2 binding protein 2.2328
LPAR2 lysophosphatidic acid receptor 2 2.2327
REG3A regenerating islet-derived 3 alpha 2.2316
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.2306
KDM4C lysine (K)-specific demethylase 4C 2.22957
CCDC70 coiled-coil domain containing 70 2.22905
SNX24 sorting nexin 24 2.2284
SCRN3 secernin 3 2.22815
SIK3 SIK family kinase 3 2.22755
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.22725
PRKCE protein kinase C, epsilon 2.227
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.22698
JAM2 junctional adhesion molecule 2 2.2256
LGI2 leucine-rich repeat LGI family, member 2 2.22395
ATXN7L1 ataxin 7-like 1 2.2229
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.22275
HSPA1A heat shock 70kDa protein 1A 2.21985
NUCB1 nucleobindin 1 2.21917
OXCT2 3-oxoacid CoA transferase 2 2.2185
IFT70A intraflagellar transport 70A 2.21845
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.2177
NLRP3 NLR family, pyrin domain containing 3 2.21524
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.2147
FFAR2 free fatty acid receptor 2 2.2125
OR10H2 olfactory receptor, family 10, subfamily H, member 2 2.21225
RAD54B RAD54 homolog B (S. cerevisiae) 2.212
DZIP3 DAZ interacting zinc finger protein 3 2.21155
MCM3 minichromosome maintenance complex component 3 2.21105
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.2102
EGFR epidermal growth factor receptor 2.20909
S100PBP S100P binding protein 2.20555
ARMH3 armadillo like helical domain containing 3 2.2051
CCDC15 coiled-coil domain containing 15 2.20395
TRIM62 tripartite motif containing 62 2.20283
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.20278
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.20247
COL6A2 collagen, type VI, alpha 2 2.20173
CELA3B chymotrypsin-like elastase family, member 3B 2.201
SNX1 sorting nexin 1 2.19998
GBP2 guanylate binding protein 2, interferon-inducible 2.199
JPH3 junctophilin 3 2.1971
BFSP1 beaded filament structural protein 1, filensin 2.1966
CCL23 chemokine (C-C motif) ligand 23 2.19632
MGLL monoglyceride lipase 2.1962
ZCCHC4 zinc finger, CCHC domain containing 4 2.19545
FOCAD focadhesin 2.19335
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.19285
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.1915
SNX27 sorting nexin family member 27 2.18975
ELOA2 elongin A2 2.1894
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.18825
ARHGAP10 Rho GTPase activating protein 10 2.18605
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 2.18512
SCRT1 scratch family zinc finger 1 2.18305
HEATR3 HEAT repeat containing 3 2.18145
MAP7D3 MAP7 domain containing 3 2.18123
AANAT aralkylamine N-acetyltransferase 2.1803
EVX1 even-skipped homeobox 1 2.1788
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.17505
CASR calcium-sensing receptor 2.17438
POLR1A polymerase (RNA) I polypeptide A, 194kDa 2.17408
DZIP1 DAZ interacting zinc finger protein 1 2.1732
CBR4 carbonyl reductase 4 2.173
BEST2 bestrophin 2 2.1721
CCDC134 coiled-coil domain containing 134 2.1702
MTA2 metastasis associated 1 family, member 2 2.1696
RASIP1 Ras interacting protein 1 2.16885
TRIM28 tripartite motif containing 28 2.1676
PEX12 peroxisomal biogenesis factor 12 2.16745
IFNA8 interferon, alpha 8 2.1657
CTTN cortactin 2.1656
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2.16438
FOXN1 forkhead box N1 2.15905
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.15795
CCDC82 coiled-coil domain containing 82 2.15785
PARP12 poly (ADP-ribose) polymerase family, member 12 2.1571
SLAMF1 signaling lymphocytic activation molecule family member 1 2.1564
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.1562
TOP3B topoisomerase (DNA) III beta 2.15583
PLAA phospholipase A2-activating protein 2.15427
CSPG4 chondroitin sulfate proteoglycan 4 2.15193
ZNF226 zinc finger protein 226 2.15185
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 2.1509
PTOV1 prostate tumor overexpressed 1 2.1503
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 2.14945
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.1486
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.1485
KANK1 KN motif and ankyrin repeat domains 1 2.1483
PISD phosphatidylserine decarboxylase 2.1481
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.14775
SGMS1 sphingomyelin synthase 1 2.14665
OLFML1 olfactomedin-like 1 2.14665
ZBTB6 zinc finger and BTB domain containing 6 2.1429
SLC12A9 solute carrier family 12, member 9 2.1425
CBX7 chromobox homolog 7 2.14195
TACC1 transforming, acidic coiled-coil containing protein 1 2.14062
ZBTB48 zinc finger and BTB domain containing 48 2.1394
RHD Rh blood group, D antigen 2.13755
CCDC40 coiled-coil domain containing 40 2.13447
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.1344
SACS sacsin molecular chaperone 2.12995
ONECUT1 one cut homeobox 1 2.12995
TBCEL tubulin folding cofactor E-like 2.12955
HOXA10 homeobox A10 2.1276
NGF nerve growth factor (beta polypeptide) 2.1267
IPP intracisternal A particle-promoted polypeptide 2.1257
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.12235
CPNE6 copine VI (neuronal) 2.12182
EP400 E1A binding protein p400 2.1209
SLC38A4 solute carrier family 38, member 4 2.12065
ARSL arylsulfatase L 2.12055
CCL15 chemokine (C-C motif) ligand 15 2.11935
MUC2 mucin 2, oligomeric mucus/gel-forming 2.11885
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.1186
ODR4 odr-4 GPCR localization factor homolog 2.11835
IFT74 intraflagellar transport 74 2.11825
SGSH N-sulfoglucosamine sulfohydrolase 2.11787
WNT2B wingless-type MMTV integration site family, member 2B 2.11753
FOXE3 forkhead box E3 2.11685
LBX1 ladybird homeobox 1 2.1167
SSX1 synovial sarcoma, X breakpoint 1 2.116
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 2.11495
ZNF750 zinc finger protein 750 2.11255
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.11206
JPH2 junctophilin 2 2.11205
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 2.11135
BPGM 2,3-bisphosphoglycerate mutase 2.11105
SYTL3 synaptotagmin-like 3 2.10905
TCF15 transcription factor 15 (basic helix-loop-helix) 2.104
AKR1C4 aldo-keto reductase family 1, member C4 2.1035
LEFTY1 left-right determination factor 1 2.1032
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.10295
TMEM47 transmembrane protein 47 2.10252
GCM2 glial cells missing homolog 2 (Drosophila) 2.1021
ZBTB32 zinc finger and BTB domain containing 32 2.1014
SLC43A3 solute carrier family 43, member 3 2.10133
ZNF442 zinc finger protein 442 2.10005
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 2.09947
ASPA aspartoacylase 2.0994
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2.09855
LRRC3 leucine rich repeat containing 3 2.096
CELA3A chymotrypsin-like elastase family, member 3A 2.09555
SBNO1 strawberry notch homolog 1 (Drosophila) 2.0942
GPC3 glypican 3 2.09385
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.09135
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.0913
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.0905
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 2.08805
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.08768
RPAIN RPA interacting protein 2.0854
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.08495
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.08455
SPOP speckle-type POZ protein 2.08285
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.08235
CDON cell adhesion associated, oncogene regulated 2.08205
HIC1 hypermethylated in cancer 1 2.0814
ZNF324 zinc finger protein 324 2.08095
MEOX2 mesenchyme homeobox 2 2.07955
TTC23 tetratricopeptide repeat domain 23 2.07915
PINK1 PTEN induced putative kinase 1 2.07877
ZNF254 zinc finger protein 254 2.07825
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.07795
MMP3 matrix metallopeptidase 3 2.0773
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.07695
MAP3K6 mitogen-activated protein kinase kinase kinase 6 2.0752
REG1B regenerating islet-derived 1 beta 2.0722
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.07075
LAG3 lymphocyte-activation gene 3 2.0705
ZNF460 zinc finger protein 460 2.07015
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.07005
UROD uroporphyrinogen decarboxylase 2.0687
CHODL chondrolectin 2.0682
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.0676
STX11 syntaxin 11 2.06675
IGSF6 immunoglobulin superfamily, member 6 2.06595
GPD1L glycerol-3-phosphate dehydrogenase 1-like 2.06585
STAG2 stromal antigen 2 2.06345
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.06322
TCF21 transcription factor 21 2.0631
EXTL3 exostosin-like glycosyltransferase 3 2.06308
CTRL chymotrypsin-like 2.0617
HOXD9 homeobox D9 2.06085
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2.0598
PRR5L proline rich 5 like 2.0585
TRIM45 tripartite motif containing 45 2.0582
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.0577
PBRM1 polybromo 1 2.05702
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.05699
RABAC1 Rab acceptor 1 (prenylated) 2.0565
IL21R interleukin 21 receptor 2.05535
PARP11 poly (ADP-ribose) polymerase family, member 11 2.05315
KRT14 keratin 14, type I 2.0531
CCNJL cyclin J-like 2.0531
SH3BP1 SH3-domain binding protein 1 2.05295
CEP112 centrosomal protein 112kDa 2.04925
BMP8B bone morphogenetic protein 8b 2.0486
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.0475
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.04745
SMTN smoothelin 2.04682
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 2.04602
SCRG1 stimulator of chondrogenesis 1 2.0457
HID1 HID1 domain containing 2.04502
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.0445
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.04395
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.04375
FBXO22 F-box protein 22 2.042
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 2.04152
GYPE glycophorin E (MNS blood group) 2.04135
PNLIP pancreatic lipase 2.0399
CD72 CD72 molecule 2.03765
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.0344
IL36A interleukin 36, alpha 2.0332
ELL2 elongation factor, RNA polymerase II, 2 2.03255
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.0323
KLK1 kallikrein 1 2.0323
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.03135
FHL5 four and a half LIM domains 5 2.0312
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.03115
GPR183 G protein-coupled receptor 183 2.03075
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.03044
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.0304
KMT2B lysine (K)-specific methyltransferase 2B 2.0304
MIMS2 mitochondrial inner membrane scaffold 2 2.0291
GOLGA3 golgin A3 2.028
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 2.02705
TRIM46 tripartite motif containing 46 2.026
SKA1 spindle and kinetochore associated complex subunit 1 2.0256
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.02557
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.02465
CD8A CD8a molecule 2.02445
PID1 phosphotyrosine interaction domain containing 1 2.0238
ZNF80 zinc finger protein 80 2.02345
NSF N-ethylmaleimide-sensitive factor 2.0222
GBA1 glucosylceramidase beta 1 2.02172
CCN3 cellular communication network factor 3 2.02132
DGKQ diacylglycerol kinase, theta 110kDa 2.0209
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 2.0205
RPAP2 RNA polymerase II associated protein 2 2.02025
PAQR5 progestin and adipoQ receptor family member V 2.02015
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 2.01945
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.01415
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.01415
ATG4A autophagy related 4A, cysteine peptidase 2.0135
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.0113
GATD3 glutamine amidotransferase class 1 domain containing 3 2.0109
TEF thyrotrophic embryonic factor 2.01085
UBE4B ubiquitination factor E4B 2.00799
MACO1 macoilin 1 2.00755
WDR19 WD repeat domain 19 2.0059
CXCL6 chemokine (C-X-C motif) ligand 6 2.0051
AVPR1A arginine vasopressin receptor 1A 2.0047
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.0041
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.00305
PRKD2 protein kinase D2 2.00243
STK11 serine/threonine kinase 11 2.0002

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -10.0
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -10.0
FASTKD5 FAST kinase domains 5 -9.02935
TLCD3A TLC domain containing 3A -8.9755
CCNB1 cyclin B1 -7.25875
GNAS GNAS complex locus -6.1755
ACOT9 acyl-CoA thioesterase 9 -6.1444
COG7 component of oligomeric golgi complex 7 -5.9843
KDM3A lysine (K)-specific demethylase 3A -5.74025
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.62365
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -5.5508
GADD45A growth arrest and DNA-damage-inducible, alpha -5.31045
SPAG4 sperm associated antigen 4 -5.2328
DNM1L dynamin 1-like -5.1332
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -5.10625
CCDC86 coiled-coil domain containing 86 -5.0631
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.02345
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.0
PEG10 paternally expressed 10 -5.0
DSG2 desmoglein 2 -4.9953
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.9886
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.9425
MRPS2 mitochondrial ribosomal protein S2 -4.90015
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.8858
ISOC1 isochorismatase domain containing 1 -4.87995
NGRN neugrin, neurite outgrowth associated -4.8304
PCNA proliferating cell nuclear antigen -4.77245
CHMP4B charged multivesicular body protein 4B -4.73365
NRIP1 nuclear receptor interacting protein 1 -4.67027
BLCAP bladder cancer associated protein -4.58275
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.5633
ITGB1BP1 integrin beta 1 binding protein 1 -4.531
DCK deoxycytidine kinase -4.5185
RGS19 regulator of G-protein signaling 19 -4.48275
TRIB3 tribbles pseudokinase 3 -4.30175
NVL nuclear VCP-like -4.2964
HSPE1 heat shock 10kDa protein 1 -4.0679
MZT2A mitotic spindle organizing protein 2A -3.99775
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.9242
YME1L1 YME1-like 1 ATPase -3.90575
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.88077
ZNF629 zinc finger protein 629 -3.823
PRPF4 pre-mRNA processing factor 4 -3.78692
THAP11 THAP domain containing 11 -3.628
COX7B cytochrome c oxidase subunit VIIb -3.5961
RABEPK Rab9 effector protein with kelch motifs -3.49885
TBCB tubulin folding cofactor B -3.45705
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -3.45595
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -3.41615
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.41265
UBFD1 ubiquitin family domain containing 1 -3.3983
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -3.3895
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.3556
NOL8 nucleolar protein 8 -3.35045
RPS27L ribosomal protein S27-like -3.33185
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -3.3309
CCDC59 coiled-coil domain containing 59 -3.3127
MAIP1 matrix AAA peptidase interacting protein 1 -3.3092
PRDX4 peroxiredoxin 4 -3.28635
RNFT1-DT RNFT1 divergent transcript -3.2588
MRPL33 mitochondrial ribosomal protein L33 -3.2548
RNF113A ring finger protein 113A -3.20785
USP6NL USP6 N-terminal like -3.2044
COX5B cytochrome c oxidase subunit Vb -3.19432
TOPBP1 topoisomerase (DNA) II binding protein 1 -3.18215
SAC3D1 SAC3 domain containing 1 -3.15245
PPP1R26 protein phosphatase 1, regulatory subunit 26 -3.13965
ZW10 zw10 kinetochore protein -3.1311
TMEM258 transmembrane protein 258 -3.09775
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -3.0749
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.04335
TXNDC9 thioredoxin domain containing 9 -3.03758
PDZD2 PDZ domain containing 2 -3.02505
C2CD2 C2 calcium-dependent domain containing 2 -2.99385
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.99235
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -2.9892
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.9859
WDR37 WD repeat domain 37 -2.97745
SCAND1 SCAN domain containing 1 -2.974
SPDEF SAM pointed domain containing ETS transcription factor -2.96445
ZFP30 ZFP30 zinc finger protein -2.93245
BOLA2B bolA family member 2B -2.9187
ESYT1 extended synaptotagmin-like protein 1 -2.9155
RPS17 ribosomal protein S17 -2.90968
RUFY1 RUN and FYVE domain containing 1 -2.9049
CD320 CD320 molecule -2.90265
EMC7 ER membrane protein complex subunit 7 -2.8758
RNF139 ring finger protein 139 -2.87465
RPS12 ribosomal protein S12 -2.86015
GCC2 GRIP and coiled-coil domain containing 2 -2.85355
DCTPP1 dCTP pyrophosphatase 1 -2.8509
RPS4X ribosomal protein S4, X-linked -2.84952
RND3 Rho family GTPase 3 -2.8492
ZNF467 zinc finger protein 467 -2.8467
ATOX1 antioxidant 1 copper chaperone -2.82625
TOR1A torsin family 1, member A (torsin A) -2.82475
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.8234
CDKN3 cyclin-dependent kinase inhibitor 3 -2.82325
IER5 immediate early response 5 -2.8201
TXNL1 thioredoxin-like 1 -2.81525
WDR12 WD repeat domain 12 -2.8081
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.80585
MRPL40 mitochondrial ribosomal protein L40 -2.80272
FNTA farnesyltransferase, CAAX box, alpha -2.79593
IFNGR1 interferon gamma receptor 1 -2.79028
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.78375
CPTP ceramide-1-phosphate transfer protein -2.75725
PRR7 proline rich 7 (synaptic) -2.75445
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.7491
TTI1 TELO2 interacting protein 1 -2.74885
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.7446
ECT2 epithelial cell transforming 2 -2.7423
ANXA4 annexin A4 -2.73362
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.72575
TPT1 tumor protein, translationally-controlled 1 -2.72013
RPS10 ribosomal protein S10 -2.71737
RWDD1 RWD domain containing 1 -2.712
OSER1 oxidative stress responsive serine-rich 1 -2.7045
MZT2B mitotic spindle organizing protein 2B -2.701
RPS19 ribosomal protein S19 -2.67945
ASPHD1 aspartate beta-hydroxylase domain containing 1 -2.67065
RPL41 ribosomal protein L41 -2.66275
RPS18 ribosomal protein S18 -2.66115
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.65218
SINHCAF SIN3-HDAC complex associated factor -2.6495
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -2.63085
RPL12 ribosomal protein L12 -2.62693
FASTKD3 FAST kinase domains 3 -2.60875
RNF167 ring finger protein 167 -2.5877
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -2.58575
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.5802
RAB5IF RAB5 interacting factor -2.57495
NXT1 nuclear transport factor 2-like export factor 1 -2.57125
RMI1 RecQ mediated genome instability 1 -2.57085
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.56753
RPL7A ribosomal protein L7a -2.5537
NRDC nardilysin convertase -2.55195
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 -2.5512
ATP5F1E ATP synthase F1 subunit epsilon -2.54865
TPX2 TPX2, microtubule-associated -2.5459
CKS2 CDC28 protein kinase regulatory subunit 2 -2.54335
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -2.5408
MRPL35 mitochondrial ribosomal protein L35 -2.5356
BBLN bublin coiled coil protein -2.53147
CLIC4 chloride intracellular channel 4 -2.53013
CTSH cathepsin H -2.52525
TRAPPC12 trafficking protein particle complex 12 -2.525
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.5211
SPATS2 spermatogenesis associated, serine-rich 2 -2.5182
MRPL34 mitochondrial ribosomal protein L34 -2.51555
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.5065
UNC50 unc-50 homolog (C. elegans) -2.50385
SNRPG small nuclear ribonucleoprotein polypeptide G -2.50265
CYB5R3 cytochrome b5 reductase 3 -2.50165
RPL9 ribosomal protein L9 -2.49995
LIMS1 LIM and senescent cell antigen-like domains 1 -2.49178
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.4915
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.48655
RPL32 ribosomal protein L32 -2.4854
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.4826
RPS23 ribosomal protein S23 -2.4694
BCL7C B-cell CLL/lymphoma 7C -2.46225
RPL23A ribosomal protein L23a -2.46077
MRPL23 mitochondrial ribosomal protein L23 -2.46015
THOC7 THO complex 7 -2.45855
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.4529
PIEZO2 piezo-type mechanosensitive ion channel component 2 -2.45035
ZNF274 zinc finger protein 274 -2.4492
ND5 NADH dehydrogenase subunit 5 -2.44365
EMC8 ER membrane protein complex subunit 8 -2.44335
CCNG1 cyclin G1 -2.44175
ZNF133 zinc finger protein 133 -2.43985
RPL30 ribosomal protein L30 -2.4351
NKRF NFKB repressing factor -2.43105
WAC WW domain containing adaptor with coiled-coil -2.43095
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.4301
FBRS fibrosin -2.4155
TRIM8 tripartite motif containing 8 -2.41315
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.41155
TMEM268 transmembrane protein 268 -2.4048
FBXO28 F-box protein 28 -2.39723
YEATS2 YEATS domain containing 2 -2.3951
ATP5MJ ATP synthase membrane subunit j -2.39437
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.3934
AGFG1 ArfGAP with FG repeats 1 -2.38785
POMK protein-O-mannose kinase -2.37252
SMIM40 small integral membrane protein 40 -2.3668
ATRAID all-trans retinoic acid-induced differentiation factor -2.36595
TBC1D15 TBC1 domain family, member 15 -2.3656
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.36545
CTNND1 catenin (cadherin-associated protein), delta 1 -2.35848
CCL20 chemokine (C-C motif) ligand 20 -2.3575
NOPCHAP1 NOP protein chaperone 1 -2.35025
RAI14 retinoic acid induced 14 -2.34865
RPP25 ribonuclease P/MRP 25kDa subunit -2.3458
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough -2.34095
NFU1 NFU1 iron-sulfur cluster scaffold -2.33755
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.33215
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.3266
ERH enhancer of rudimentary homolog (Drosophila) -2.32115
SMG8 SMG8 nonsense mediated mRNA decay factor -2.3178
RPL37 ribosomal protein L37 -2.3124
RNF39 ring finger protein 39 -2.3101
MOAP1 modulator of apoptosis 1 -2.30975
SESN1 sestrin 1 -2.30465
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.30225
HINT1 histidine triad nucleotide binding protein 1 -2.2969
RPL39 ribosomal protein L39 -2.29685
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.29395
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.2908
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough -2.2906
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.29047
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -2.28965
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.2875
MRPL48 mitochondrial ribosomal protein L48 -2.2874
COMMD1 copper metabolism (Murr1) domain containing 1 -2.27905
MRPS17 mitochondrial ribosomal protein S17 -2.27275
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -2.25678
OSMR oncostatin M receptor -2.2554
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.2538
COXFA4 cytochrome c oxidase associated subunit FA4 -2.25135
ZNF146 zinc finger protein 146 -2.2462
GMFG glia maturation factor, gamma -2.2388
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.23432
NANS N-acetylneuraminic acid synthase -2.2328
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.23135
LMAN2L lectin, mannose-binding 2-like -2.2288
NUP93 nucleoporin 93kDa -2.22395
DDRGK1 DDRGK domain containing 1 -2.2193
NOP10 NOP10 ribonucleoprotein -2.21475
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.2091
RPS24 ribosomal protein S24 -2.20815
CA8 carbonic anhydrase VIII -2.2019
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.2012
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.19985
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -2.1998
HRAS Harvey rat sarcoma viral oncogene homolog -2.1976
RALY RALY heterogeneous nuclear ribonucleoprotein -2.19665
RBM15 RNA binding motif protein 15 -2.19343
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.19075
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.19003
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1898
COA7 cytochrome c oxidase assembly factor 7 (putative) -2.1869
AP3M2 adaptor-related protein complex 3, mu 2 subunit -2.1846
TOR1AIP2 torsin A interacting protein 2 -2.18115
UTP25 UTP25 small subunit processome component -2.1755
MPC1 mitochondrial pyruvate carrier 1 -2.17115
ACTMAP actin maturation protease -2.17055
RPL36 ribosomal protein L36 -2.17
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.16595
GPN1 GPN-loop GTPase 1 -2.1649
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.16418
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -2.1561
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -2.15565
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -2.1502
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.13527
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.1338
PHF21A PHD finger protein 21A -2.1309
HLA-DMA major histocompatibility complex, class II, DM alpha -2.13055
BRIX1 BRX1, biogenesis of ribosomes -2.12775
KIF2A kinesin heavy chain member 2A -2.12702
TOR4A torsin family 4, member A -2.12515
RPS3A ribosomal protein S3A -2.1244
TSC1 tuberous sclerosis 1 -2.12425
UBC ubiquitin C -2.12402
PDCD5 programmed cell death 5 -2.12
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.1188
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1132
PPID peptidylprolyl isomerase D -2.11155
MRPL17 mitochondrial ribosomal protein L17 -2.1099
RNASET2 ribonuclease T2 -2.10847
GEMIN6 gem (nuclear organelle) associated protein 6 -2.10725
TMED1 transmembrane emp24 protein transport domain containing 1 -2.1063
PTPRA protein tyrosine phosphatase, receptor type, A -2.10486
TSPOAP1 TSPO associated protein 1 -2.10445
RPP38 ribonuclease P/MRP 38kDa subunit -2.10425
PNO1 partner of NOB1 homolog (S. cerevisiae) -2.103
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.09975
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.09955
MCFD2 multiple coagulation factor deficiency 2 -2.0976
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.09215
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.0863
RBP3 retinol binding protein 3, interstitial -2.08525
SH3GL3 SH3-domain GRB2-like 3 -2.08505
PLA2G15 phospholipase A2, group XV -2.0824
SYNGR3 synaptogyrin 3 -2.0779
MYNN myoneurin -2.0721
PPP1R13B protein phosphatase 1, regulatory subunit 13B -2.0709
CLDN6 claudin 6 -2.0703
SEC61G Sec61 gamma subunit -2.0702
KRT10 keratin 10, type I -2.06682
MYDGF myeloid-derived growth factor -2.06645
MNT MAX network transcriptional repressor -2.0591
F5 coagulation factor V (proaccelerin, labile factor) -2.05722
EXOSC8 exosome component 8 -2.0571
SLC61A1 solute carrier family 61 member 1 -2.0556
SEC16A SEC16 homolog A (S. cerevisiae) -2.05445
SNAP29 synaptosomal-associated protein, 29kDa -2.05405
CDC73 cell division cycle 73 -2.054
RGS10 regulator of G-protein signaling 10 -2.04873
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.0484
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -2.0422
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -2.03145
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.02845
SPATA5L1 spermatogenesis associated 5-like 1 -2.02413
RPL35 ribosomal protein L35 -2.0223
BTK Bruton agammaglobulinemia tyrosine kinase -2.0223
APMAP adipocyte plasma membrane associated protein -2.0214
TTC27 tetratricopeptide repeat domain 27 -2.0197
CYB5A cytochrome b5 type A (microsomal) -2.01953
TFRC transferrin receptor -2.0185
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -2.01628
ZMPSTE24 zinc metallopeptidase STE24 -2.01615
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.0161
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.0156
BFAR bifunctional apoptosis regulator -2.01305
COX7C cytochrome c oxidase subunit VIIc -2.01175
SQLE squalene epoxidase -2.00938
EFCAB14 EF-hand calcium binding domain 14 -2.0064
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.00443
PDCL3 phosducin-like 3 -2.00255
CAMLG calcium modulating ligand -2.00195
HOXC11 homeobox C11 -2.00175