CRCGN008_HEPG2_24H:A05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the CRCGN008_HEPG2_24H:A05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 6.6037
GPATCH8 G patch domain containing 8 5.93048
CBR3 carbonyl reductase 3 5.203
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.1128
CARMIL1 capping protein regulator and myosin 1 linker 1 4.78195
ATP11B ATPase, class VI, type 11B 4.71225
MAMLD1 mastermind-like domain containing 1 4.64555
LOC122526780 uncharacterized LOC122526780 4.2343
HOXA10 homeobox A10 4.08685
SNAP25 synaptosomal-associated protein, 25kDa 4.02525
CXCR4 chemokine (C-X-C motif) receptor 4 3.97673
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.68837
STK25 serine/threonine kinase 25 2.92075
TNIP1 TNFAIP3 interacting protein 1 2.7435
ADAT1 adenosine deaminase, tRNA-specific 1 2.61675
TLR4 toll-like receptor 4 2.5096
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.46915
STXBP1 syntaxin binding protein 1 2.1843
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.18135
FAM222B family with sequence similarity 222, member B 2.15395
RBM34 RNA binding motif protein 34 2.15328
TMEM11 transmembrane protein 11 2.11355
PPIG peptidylprolyl isomerase G (cyclophilin G) 2.09603
CREG1 cellular repressor of E1A-stimulated genes 1 2.0954
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.08655
LUM lumican 2.02335

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -8.26692
LOC124907782 dual specificity protein phosphatase 22 -8.114
NT5DC2 5'-nucleotidase domain containing 2 -5.0897
CDC20 cell division cycle 20 -5.0
FABP5 fatty acid binding protein 5 (psoriasis-associated) -5.0
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.9755
DNM1L dynamin 1-like -4.96225
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.8693
ZMIZ1 zinc finger, MIZ-type containing 1 -4.33065
CCNB2 cyclin B2 -3.37185
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.3637
ACAA1 acetyl-CoA acyltransferase 1 -2.8412
CCNH cyclin H -2.58055
LGALSL lectin, galactoside-binding-like -2.4221
BMP3 bone morphogenetic protein 3 -2.37485
PEG10 paternally expressed 10 -2.3496
COG7 component of oligomeric golgi complex 7 -2.2825
PRSS3 protease, serine, 3 -2.24755
PTK6 protein tyrosine kinase 6 -2.24465
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -2.2068
ENDOU endonuclease, polyU-specific -2.16875
EDN3 endothelin 3 -2.1542
KLK8 kallikrein-related peptidase 8 -2.13995
LY6G6C lymphocyte antigen 6 complex, locus G6C -2.1314
NRIP1 nuclear receptor interacting protein 1 -2.12765
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.1168
RIPPLY3 ripply transcriptional repressor 3 -2.11135
TMEM40 transmembrane protein 40 -2.0794
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.06075
POU2F3 POU class 2 homeobox 3 -2.05032
FKBP4 FK506 binding protein 4, 59kDa -2.02038
DAZL deleted in azoospermia-like -2.00955
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -2.00478
KLK5 kallikrein-related peptidase 5 -2.00305