CRCGN008_HEPG2_24H:A17 Gene Set
Genes
60 genes differentially expressed following the CRCGN008_HEPG2_24H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
5.1099
|
|
UBQLN2
|
ubiquilin 2
|
5.1016
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.75095
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.6043
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.5572
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.42445
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.39135
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.30735
|
|
MOK
|
MOK protein kinase
|
3.8994
|
|
EGF
|
epidermal growth factor
|
3.8769
|
|
SATB1
|
SATB homeobox 1
|
3.7726
|
|
CDCA4
|
cell division cycle associated 4
|
3.5169
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.26505
|
|
CYCS
|
cytochrome c, somatic
|
3.19595
|
|
CCNF
|
cyclin F
|
3.11755
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.93665
|
|
CHEK2
|
checkpoint kinase 2
|
2.71655
|
|
NMU
|
neuromedin U
|
2.6976
|
|
ZNF589
|
zinc finger protein 589
|
2.5946
|
|
KIF20A
|
kinesin family member 20A
|
2.5183
|
|
DENND4B
|
DENN/MADD domain containing 4B
|
2.4095
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.405
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.35488
|
|
DTWD1
|
DTW domain containing 1
|
2.33795
|
|
KIF5C
|
kinesin family member 5C
|
2.32865
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.31015
|
|
AXIN1
|
axin 1
|
2.267
|
|
MTHFSD
|
methenyltetrahydrofolate synthetase domain containing
|
2.25955
|
|
DCAF16
|
DDB1 and CUL4 associated factor 16
|
2.2021
|
|
BAZ1A
|
bromodomain adjacent to zinc finger domain, 1A
|
2.09162
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
2.0354
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
2.01055
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.73505
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.22825
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.0982
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.09765
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.93895
|
|
DNM1L
|
dynamin 1-like
|
-4.90645
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.88208
|
|
LDHD
|
lactate dehydrogenase D
|
-4.87175
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-4.82635
|
|
MAP7
|
microtubule-associated protein 7
|
-4.78248
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.9837
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.81255
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.5273
|
|
CLIC4
|
chloride intracellular channel 4
|
-3.51958
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-3.4263
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.35208
|
|
TWF2
|
twinfilin actin binding protein 2
|
-3.3094
|
|
CD320
|
CD320 molecule
|
-2.94845
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.94255
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.8387
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.77845
|
|
SNX11
|
sorting nexin 11
|
-2.54993
|
|
RBM34
|
RNA binding motif protein 34
|
-2.26513
|
|
DNAJC12
|
DnaJ (Hsp40) homolog, subfamily C, member 12
|
-2.22155
|
|
MFGE8
|
milk fat globule-EGF factor 8 protein
|
-2.19135
|
|
NECTIN2
|
nectin cell adhesion molecule 2
|
-2.1371
|
|
HDAC1
|
histone deacetylase 1
|
-2.09855
|
|
CLTC
|
clathrin, heavy chain (Hc)
|
-2.0769
|
