CRCGN008_HEPG2_24H:A18 Gene Set
Genes
56 genes differentially expressed following the CRCGN008_HEPG2_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.2217
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.9574
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.8361
|
|
RPL39L
|
ribosomal protein L39-like
|
4.6857
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.49045
|
|
NMU
|
neuromedin U
|
4.0903
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.85295
|
|
EGF
|
epidermal growth factor
|
3.77435
|
|
PRR15L
|
proline rich 15-like
|
3.6881
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.61617
|
|
TRIM13
|
tripartite motif containing 13
|
3.1812
|
|
BAX
|
BCL2-associated X protein
|
2.93913
|
|
KLHL9
|
kelch-like family member 9
|
2.86005
|
|
CYB561
|
cytochrome b561
|
2.85544
|
|
VGLL4
|
vestigial-like family member 4
|
2.83683
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.82932
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.7903
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
2.77255
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.7481
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.65875
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.60825
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.48273
|
|
SMC3
|
structural maintenance of chromosomes 3
|
2.23425
|
|
VDAC3
|
voltage-dependent anion channel 3
|
2.04848
|
|
TSPYL5
|
TSPY-like 5
|
2.027
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.02415
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.7668
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.10825
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-5.05855
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.8984
|
|
ZNF586
|
zinc finger protein 586
|
-4.72955
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.66275
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.5633
|
|
CD320
|
CD320 molecule
|
-4.28355
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.22647
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.9945
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.82167
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.1217
|
|
SESN1
|
sestrin 1
|
-3.08535
|
|
SNX11
|
sorting nexin 11
|
-2.5639
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.4764
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.41795
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.3639
|
|
ZNHIT3
|
zinc finger, HIT-type containing 3
|
-2.30115
|
|
PUS3
|
pseudouridylate synthase 3
|
-2.272
|
|
HMG20B
|
high mobility group 20B
|
-2.2462
|
|
ZNF671
|
zinc finger protein 671
|
-2.1312
|
|
MPHOSPH10
|
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
|
-2.12825
|
|
ACY1
|
aminoacylase 1
|
-2.12735
|
|
NSF
|
N-ethylmaleimide-sensitive factor
|
-2.08535
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
-2.0708
|
|
MED17
|
mediator complex subunit 17
|
-2.06105
|
|
MAP3K14
|
mitogen-activated protein kinase kinase kinase 14
|
-2.05985
|
|
NLRP1
|
NLR family, pyrin domain containing 1
|
-2.0454
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.02915
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.0232
|
