| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diethyltoluamide 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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110 genes differentially expressed following the CRCGN008_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 5.41245 |
| ADRB2 | adrenoceptor beta 2, surface | 5.0 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.79255 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.564 |
| MEF2C | myocyte enhancer factor 2C | 4.41995 |
| LOC122526780 | uncharacterized LOC122526780 | 4.3265 |
| CBR3 | carbonyl reductase 3 | 4.2877 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.28422 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.9278 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.8439 |
| CCDC85B | coiled-coil domain containing 85B | 3.8007 |
| HOXA10 | homeobox A10 | 3.68845 |
| IDE | insulin-degrading enzyme | 3.63562 |
| NOSIP | nitric oxide synthase interacting protein | 3.58285 |
| CHN1 | chimerin 1 | 3.5319 |
| EGF | epidermal growth factor | 3.43265 |
| H2BC12 | H2B clustered histone 12 | 3.29715 |
| MAP7 | microtubule-associated protein 7 | 3.2897 |
| CYCS | cytochrome c, somatic | 3.09155 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.95865 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.8967 |
| PFKL | phosphofructokinase, liver | 2.75953 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.71505 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.66033 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.56893 |
| TBP | TATA box binding protein | 2.5328 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.44945 |
| JADE2 | jade family PHD finger 2 | 2.38993 |
| JUN | jun proto-oncogene | 2.3526 |
| SNX7 | sorting nexin 7 | 2.29275 |
| EPHA3 | EPH receptor A3 | 2.2779 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 2.27545 |
| PTK2 | protein tyrosine kinase 2 | 2.24903 |
| ZNF589 | zinc finger protein 589 | 2.21343 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 2.2026 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 2.19915 |
| PFKP | phosphofructokinase, platelet | 2.1925 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 2.16258 |
| AAMP | angio-associated, migratory cell protein | 2.13625 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 2.12225 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 2.12165 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 2.11165 |
| PRPF6 | pre-mRNA processing factor 6 | 2.10203 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.10108 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 2.09375 |
| CDK6 | cyclin-dependent kinase 6 | 2.09 |
| PHF10 | PHD finger protein 10 | 2.08225 |
| ZC3H11B | zinc finger CCCH-type containing 11B pseudogene | 2.05505 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 2.04715 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 2.0342 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 2.0289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -10.0 |
| LDHD | lactate dehydrogenase D | -10.0 |
| ZNF586 | zinc finger protein 586 | -5.54745 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.9329 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.61145 |
| TCTN1 | tectonic family member 1 | -4.59635 |
| USP6NL | USP6 N-terminal like | -4.30855 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.73698 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.73247 |
| PRPF4 | pre-mRNA processing factor 4 | -3.52605 |
| CCNB2 | cyclin B2 | -3.2802 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.22515 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -3.0003 |
| SNX11 | sorting nexin 11 | -2.79262 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -2.5759 |
| GRK1 | G protein-coupled receptor kinase 1 | -2.5607 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.5538 |
| TMEM164 | transmembrane protein 164 | -2.54235 |
| CRIPT | cysteine-rich PDZ-binding protein | -2.5162 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 | -2.50885 |
| MRPL48 | mitochondrial ribosomal protein L48 | -2.49695 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.47355 |
| ANKRD10 | ankyrin repeat domain 10 | -2.4722 |
| RBM34 | RNA binding motif protein 34 | -2.43765 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 | -2.40145 |
| ZNF426 | zinc finger protein 426 | -2.37755 |
| CCNB1 | cyclin B1 | -2.37405 |
| SSTR1 | somatostatin receptor 1 | -2.3532 |
| IFT22 | intraflagellar transport 22 | -2.32055 |
| ZNF134 | zinc finger protein 134 | -2.29425 |
| ZNF324B | zinc finger protein 324B | -2.2558 |
| AGRP | agouti related neuropeptide | -2.25265 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -2.2464 |
| RNF2 | ring finger protein 2 | -2.24185 |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 | -2.1878 |
| COG7 | component of oligomeric golgi complex 7 | -2.1867 |
| KRT76 | keratin 76, type II | -2.1858 |
| MTA2 | metastasis associated 1 family, member 2 | -2.159 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -2.1587 |
| LMAN2L | lectin, mannose-binding 2-like | -2.14865 |
| SYNDIG1 | synapse differentiation inducing 1 | -2.1394 |
| WDR70 | WD repeat domain 70 | -2.1334 |
| GATAD2A | GATA zinc finger domain containing 2A | -2.1274 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -2.1016 |
| PMF1-BGLAP | PMF1-BGLAP readthrough | -2.10085 |
| SPACA9 | sperm acrosome associated 9 | -2.10025 |
| ASTN2 | astrotactin 2 | -2.0964 |
| MRPS10 | mitochondrial ribosomal protein S10 | -2.094 |
| ZNF562 | zinc finger protein 562 | -2.0879 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -2.08565 |
| ICAM3 | intercellular adhesion molecule 3 | -2.0811 |
| DGKH | diacylglycerol kinase, eta | -2.07975 |
| EPCIP | exosomal polycystin 1 interacting protein | -2.06125 |
| GAP43 | growth associated protein 43 | -2.04885 |
| WDR83OS | WD repeat domain 83 opposite strand | -2.0416 |
| LOC124900193 | uncharacterized LOC124900193 | -2.02565 |
| ZNF197 | zinc finger protein 197 | -2.022 |
| ZNF415 | zinc finger protein 415 | -2.0146 |
| NKX6-1 | NK6 homeobox 1 | -2.00775 |
