CRCGN008_HEPG2_24H:A22 Gene Set
Genes
40 genes differentially expressed following the CRCGN008_HEPG2_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.10785
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.8567
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.8306
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.6812
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.55555
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
4.09745
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.98495
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.2567
|
|
PRKCH
|
protein kinase C, eta
|
3.17385
|
|
CYCS
|
cytochrome c, somatic
|
3.1544
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.081
|
|
CYB561
|
cytochrome b561
|
3.06655
|
|
MAP7
|
microtubule-associated protein 7
|
3.04312
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.6811
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.58205
|
|
SCRN1
|
secernin 1
|
2.41835
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.09957
|
|
SLC46A3
|
solute carrier family 46, member 3
|
2.08515
|
|
ADAMTSL4
|
ADAMTS-like 4
|
2.0729
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
2.05285
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.0182
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.24735
|
|
CD320
|
CD320 molecule
|
-5.06235
|
|
CDC20
|
cell division cycle 20
|
-5.0
|
|
CCNB2
|
cyclin B2
|
-4.9619
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.7978
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.7851
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-4.60835
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-4.44795
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.31805
|
|
CD58
|
CD58 molecule
|
-4.2209
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-3.69565
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.2887
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.1789
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.82215
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.72483
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.59195
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.5696
|
|
SLIRP
|
SRA stem-loop interacting RNA binding protein
|
-2.2306
|
|
CDC25B
|
cell division cycle 25B
|
-2.0062
|
