| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diethyltoluamide 2.47 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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50 genes differentially expressed following the CRCGN008_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.2268 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.7021 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.50055 |
| IDE | insulin-degrading enzyme | 4.19712 |
| ZFP36 | ZFP36 ring finger protein | 3.9939 |
| CBR3 | carbonyl reductase 3 | 3.9038 |
| NOSIP | nitric oxide synthase interacting protein | 3.7696 |
| PRKCH | protein kinase C, eta | 3.57085 |
| SMIM40 | small integral membrane protein 40 | 3.3024 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.9332 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.9143 |
| STIMATE | STIM activating enhancer | 2.8816 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.76535 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.7495 |
| GPATCH8 | G patch domain containing 8 | 2.71275 |
| TBP | TATA box binding protein | 2.5601 |
| KLHL9 | kelch-like family member 9 | 2.4703 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.38665 |
| ELAC2 | elaC ribonuclease Z 2 | 2.2655 |
| WASF3 | WAS protein family, member 3 | 2.2179 |
| TMEM109 | transmembrane protein 109 | 2.12605 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.10315 |
| UNG | uracil-DNA glycosylase | 2.0796 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 2.02983 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.00237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC124907782 | dual specificity protein phosphatase 22 | -5.62975 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.62365 |
| ADI1 | acireductone dioxygenase 1 | -5.1686 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.35717 |
| JMJD6 | jumonji domain containing 6 | -3.97815 |
| CCNB1 | cyclin B1 | -3.8612 |
| CLIC4 | chloride intracellular channel 4 | -3.4894 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.3385 |
| CCNH | cyclin H | -3.31825 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -3.29425 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.29155 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.2776 |
| HSPA8 | heat shock 70kDa protein 8 | -3.15633 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.98052 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.7152 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.6401 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.6183 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.5695 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.421 |
| HNMT | histamine N-methyltransferase | -2.26043 |
| RPS5 | ribosomal protein S5 | -2.23585 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -2.11928 |
| SARAF | store-operated calcium entry-associated regulatory factor | -2.10025 |
| INPP1 | inositol polyphosphate-1-phosphatase | -2.09945 |
| BZW2 | basic leucine zipper and W2 domains 2 | -2.0588 |