CRCGN008_HEPG2_24H:A24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diethyltoluamide 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the CRCGN008_HEPG2_24H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.53705
E2F2 E2F transcription factor 2 5.0
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.9452
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.8328
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.721
CBR3 carbonyl reductase 3 4.5481
PEX11A peroxisomal biogenesis factor 11 alpha 4.5156
TBPL1 TBP-like 1 3.9128
SNAP25 synaptosomal-associated protein, 25kDa 3.64225
GSTZ1 glutathione S-transferase zeta 1 3.62595
GATA3 GATA binding protein 3 3.53908
PTK2 protein tyrosine kinase 2 3.38308
CDPF1 cysteine-rich, DPF motif domain containing 1 3.3663
ZNF589 zinc finger protein 589 3.11222
ADAT1 adenosine deaminase, tRNA-specific 1 3.0769
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.039
TLR4 toll-like receptor 4 2.7162
THOC2 THO complex 2 2.65625
ELAC2 elaC ribonuclease Z 2 2.6131
JADE2 jade family PHD finger 2 2.56995
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.39517
SIRT3 sirtuin 3 2.38415
SFTPB surfactant protein B 2.3824
WDTC1 WD and tetratricopeptide repeats 1 2.37027
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.3514
SCYL3 SCY1-like 3 (S. cerevisiae) 2.32385
RBM41 RNA binding motif protein 41 2.2213
ZNF281 zinc finger protein 281 2.19
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.16455
KCTD2 potassium channel tetramerization domain containing 2 2.13845
TMEM35A transmembrane protein 35A 2.12085
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.1023
MAP2K4 mitogen-activated protein kinase kinase 4 2.09963
CORO1A coronin, actin binding protein, 1A 2.0877
SYNC syncoilin, intermediate filament protein 2.0855
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.0812
MTNAP1 mitochondrial nucleoid associated protein 1 2.0481
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.03367
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.02685
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.02005
CDH18 cadherin 18, type 2 2.01025
MRPS33 mitochondrial ribosomal protein S33 2.0102

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -6.22725
NGRN neugrin, neurite outgrowth associated -5.58095
PUF60 poly-U binding splicing factor 60KDa -5.49495
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.4067
CDC20 cell division cycle 20 -5.0
CCNB2 cyclin B2 -4.9821
TUBB6 tubulin, beta 6 class V -4.93315
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.5086
ZW10 zw10 kinetochore protein -3.89645
MAPK13 mitogen-activated protein kinase 13 -3.84197
HLA-DMA major histocompatibility complex, class II, DM alpha -3.75555
FASTKD5 FAST kinase domains 5 -3.73835
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.74542
CD58 CD58 molecule -2.68623
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.6239
TXNDC9 thioredoxin domain containing 9 -2.50927
LASP1 LIM and SH3 protein 1 -2.39795
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.39608
GSDMD gasdermin D -2.35375
CCNH cyclin H -2.27735
MTCH1 mitochondrial carrier 1 -2.2579
DDIT4 DNA-damage-inducible transcript 4 -2.22975
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.2146
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough -2.14165
ASXL2 additional sex combs like transcriptional regulator 2 -2.1278
GLOD4 glyoxalase domain containing 4 -2.07905